Mesoporous Nd-doped SrTiO3 nanospheres and nanoplates with high specific surface areas have been successfully synthesized using tetra-n-butyl titanate, Sr(NO3)2, Nd(NO3)3 and NaOH in mixed solvents of ethylene glycol and deionized water by a rapid microwave-assisted solvothermal method at 200°C for 10min. Mesoporous Nd-doped SrTiO3 nanospheres are obtained at lower concentrations of the reactants. However, the product undergoes a dramatic morphological change from nanosphere to nanoplate when the concentrations of the reactants are increased. The photocatalytic activities of the samples for the degradation of methylene blue under simulated solar light irradiation (λ>290nm) and visible light irradiation (λ>420nm) are also evaluated. Both the mesoporous Nd-doped SrTiO3 nanospheres and nanoplates show higher photocatalytic activities than that of the commercial TiO2 (P25) under visible light irradiation.