A small-pillar gob-side roadway showed rockburst appearance during the mining of a gob-side working face located in the Shaanxi-Inner Mongolia mining area. This study examines the 2202 gob-side working face of a coal mine in Inner Mongolia as a case study. A stress evolution model was built for the static-stress spatial islands formed by drainage regions and goafs based on the spatial relationships between drainage regions and goafs. The average microseismic frequency and energy of the high-stress zone of spatial islands were at least 1.37 times of those of other zones, validating the presence of spatial islands. The dynamic and static load effects of working face squaring were obtained based on the evolution of the stope roof as well as changes in microseismic data. Microseismically active zones were advanced to 200 m–300 m on working faces. The rockbursts induced by high static loads and dynamic and static loads formed by spatial islands and squaring were calculated. According to calculation results, the critical stress concentration value under high static loads was 3.27; the critical static stress concentration value under dynamic and static loads was 1.81. The superposition of drainage boundary stress, goaf lateral stress, and lead stress might reach the critical stress concentration under dynamic load disturbances, causing rockbursts. A stress adjustment scheme was established, including overall hydraulic fracturing of the external roof of the drainage region, reduction of stoping speed, and pressure relief of large-diameter boreholes. The stress adjustment scheme was implemented on-site and supplemented by monitoring and early warning methods to safely advance by the first squaring region.