MgTa2O6 is a very promising microwave dielectric material, but the residual Ta2O5 which produced during the reaction process of MgO and Ta2O5 with stoichiometric ratio limits its further development. In this study, B2O3 and MgO sintering additives were applied to reduce Ta2O5 phase and enhance the microstructure and microwave dielectric properties. Results show that B2O3 has an advantages over MgO in improving the material properties, the best microwave dielectric properties (εr = 27.8, Qf = 184000 GHz, τf = 53 ppm/oC) were acquired at x(B2O3) = 0.5 wt%. The mechanisms of both B2O3 and MgO additives were analyzed in detail.