We synthesised the new initiator,N-methyl bis [(nonafluorobutane) sulfonyl] imide (Nf2NMe) for 2-oxazolines derived from bis [(nonafluorobutane) sulfonyl] imide (Nf2NH). Also we compared activity of initiator of Nf2NMe with methyl triflate (TfOMe) and whether it was living polymerization. Furtheremore, not only we synthesized new initiator (Nf2NMe) for 2-oxazolines and evaluated it, but also we created a new hybride with a bioactive glass (Bioglass®45S5) by electrophoretic deposition (EPD) because poly (2-oxazoline) s have biocompatibility. Subsequently, we immersed the poly (2-oxazoline) s / bioactive glass composite film made by EPD in simulated body fluid (SBF) to form the hydroxyapatite.