Carboxyl Methyl Research Articles

Pre-post redox electron transfer regioselectivity at the alanine modified nano graphene electrode interface

Alanine (AL) has been used as a electrode modifier to alter the carbon paste interface for sensing applications. Unfortunately, still, electron transfer (ET) properties of AL modified graphene (GR) interface are not known. Density Functional Theory (DFT) based GR interface will help to know the molecular view of interface. In the current article AL modified GR interface modeled using DFT-based frontier molecular orbital (FMO) theory and analytical Fukui functions. At the AL modified GR interface, the N atom of AL acts like an additional electron donor site, and a carboxylic acid, methyl, and amine group act like a reduction center.

Fluorinated carbon dots/carboxyl methyl cellulose sodium composite with a temperature-sensitive fluorescence/phosphorescence applicable for anti-counterfeiting marking

Carbon dots (CDs) have attracted extensive attention due to their excellent optical properties, especially in the tunable photoluminescence (PL) (including fluorescence, delayed fluorescence and phosphorescence) and high photostability. However, the thermal stimuli-responsive PL from CDs based materials is still rare reported so far. In this work, we report a facile, large-scale synthesis of a polymer nanocomposite containing fluorinated carbon dots (FCDs) by using a commercial, water-soluble polymer carboxyl methyl cellulose sodium (CMCNa) as a stabilizing matrix. The as-synthesized FCDs-CMCNa shows both solid-state fluorescence and room temperature phosphorescence (RTP). More interestingly, with temperature decreasing from 300 to 90 K, the FCDs-CMCNa presents a peculiar temperature-sensitive optical property that its fluorescence/phosphorescence intensity both increase with temperature decreasing to a turning point of 150 K and then decline gradually as temperature decreasing to 90 K. This peculiar temperature-sensitive optical property of FCDs-CMCNa can be applied in advanced anti-counterfeiting, information encryption and thermo-sensitive sensors.

A new anti-proliferative compound from an endophytic fungus, Phoma sp.

A new oxazole-type compound (1), named macrooxazole E, and three known macrooxazoles A-C (2–4), were isolated from ethyl acetate (EtOAc) extracts of Phoma sp. JS0228 cultures, an endophytic fungus of Morus alba (M. alba). Structures of the isolated compounds were determined using spectroscopic methods, such as 1 D- and 2 D-nuclear magnetic resonance (NMR) and high-resolution mass spectrometry (HRMS). Macrooxazole E (1) differed from macrooxazole C only in the presence of methyl carboxylate instead of free carboxylic acid. Macrooxazole C showed moderate anti-proliferative activities against human breast cancer (MCF-7) and prostate cancer (LNCaP) cell lines with IC50 values of 0.29 mM and 0.36 mM, respectively. This study presents the possibility of the endophytic fungus Phoma sp. JS0228 to produce new bioactive natural compounds.

Morphological and histological kidney structure in diabetic rats model treated with ethanol extracts of jengkol fruit peel (Archidendron pauciflorum)

In a long term, diabetes mellitus (DM) leads to nephropathy due to glomerular hyperfiltration. One of the plant used as a diabetic drug by the community in Karangwangi Village, Cianjur Regency, West Java is the fruit peel of jengkol. Therefore, this study aims to determine the effect of the ethanolic extract of Jengkol fruit peel (EEJFP) toward the morphological and histological structure on the kidney of the diabetic rat model. The method adopted was the Randomized Design (CRD) with 6 treatments namely NC (Carboxyl Methyl Cellulose (CMC) 0.5%), PC (CMC 0.5%), Pb (Glibenclamide 5 mg/kg BW), P1, P2, and P3 (EEJFP 385; 770; and 1,540 mg/kg BW) with 4 replications for 14 consecutive days. Furthermore, the induction of diabetes with streptozotocin dose of 60 mg/Kg BW was performed intravenously in experimental animals except for the NC group. The parameters observed include relative weight, morphological, and histological structure of kidney which include glomerular diameter, Bowman space distance, and percentage of proximal tubular cell necrosis. The non-parametric and parametric data were tested by Kruskal Wallis and ANOVA test as well as Duncan's follow-up test, respectively. The results showed that there was no significant difference in the morphological structure of the kidney between treatment groups. Furthermore, the relative weights of kidney in the PC, Pb, P1, and P3 groups were larger and significantly different compared to NC and P2 also, the histological structure showed that the glomerular diameter (65.43 ± 0.7 m), Bowman space distance (4.19 ± 1.7 µm), and the percentage of proximal tubular cell necrosis (24.6 ± 5.5%) at P2 were not significantly different from NC. Based on this results, it was concluded that EEJFP has no effect on the kidney’s morphological structure, however, it decreases its relative weight and repair the kidney’s histological damage of the diabetic rat model with the optimum dose of 770 mg/kg BW.

Ni‐Catalyzed Direct Carboxylation of Aryl C−H Bonds in Benzamides with CO2

AbstractThe direct carboxylation of inert aryl C−H bond catalyzed by abundant and cheap nickel is still facing challenge. Herein, we report the Ni‐catalyzed direct carboxylation of aryl C−H bonds in benzamides under 1 atm of CO2 to afford various methyl carboxylates or phthalimides, dealing with different post‐processing. The reaction displays excellent functional group tolerance and affords moderate to high carboxylation yields under mild conditions. Detail mechanistic studies suggest that a Ni(0)−Ni(II)−Ni(I) catalytic cycle may be involved in this reaction.magnified image

Skin Regeneration by Hybrid Carboxyl Methyl Cellulose/Calcium Alginate Fibers Electrospun Scaffold

ABSTRACT This study aimed to investigate on elasticity, degradation, and mechanical strength of sodium carboxyl methyl cellulose (SCMC) and calcium alginate (CA)-based scaffolds and their effect on fibroblasts’ proliferation and adhesion. Using electrospinning technique by employing natural polymers provides a progressive approach in tissue engineering by producing similar structure with adjustable properties. Scanning electron microscope (SEM) was applied to observe the morphological and textural properties. Physico-chemical properties were studied using FTIR, tensile strain, contact angle, in vitro degradation, and water absorption test, and the biological properties were conducted by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay and SEM observations. The results showed that a bead-free fibers was produced with over 80% porosity. CA resulted in enhancing elasticity, wettability, water uptake absorption, and increasing the rate of biodegradation. Biological assessment revealed that fibroblast cells were adhered and proliferated on SCMC/CA scaffold better comparable with pure SCMC scaffold. The overall findings denoted to the chemical, mechanical, hydrophilicity and biological suitability of SCMC/CA nanofiber scaffolds that make it a promising candidate for further studies toward skin tissue engineering applications.

Characterization and Topical Study of Aloe Vera Hydrogel on Wound-Healing Process.

Wound healing is fundamental to restore the tissue integrity. A topical study of the influence of Aloe vera hydrogel, formulated with 1,2-propanediol (propanediol) and triethanolamine (TEA), on the skin wound-healing process was investigated in female Wistar rats. FTIR spectroscopy confirms the presence of carboxylic acid and methyl ester carboxylate groups related with important compounds that confer the hydrogel a good interaction with proteins and growth factors. SEM images show a microstructure and micro-roughness that promote a good adhesion to the wound. Therefore, the swelling kinetics and the contact angle response contribute to the understanding of the in vivo results of the animal test. The results indicated that the Aloe vera hydrogel, prepared with propanediol and TEA, together with its superficial characteristics, improve its rapid penetration without drying out the treated tissue. This produced a positive influence on inflammation, angiogenesis, and wound contraction, reducing 29% the total healing time, reaching the total closure of the wound in 15 days.

Cellulose Degrading Ability of Bacterial Strains Isolated from Gut of Termites in Vinhlong Province - Vietnam

Cellulose are the most abundant renewable biomass. The bioconversion of cellulose plays an important role for sustainable development and application in alcohol production, compost production and waste treatment. Termites were known as the most successful wood-degrading species on the earth, can degrade in large quantities of cellulosic biomass by activities of enzymes secreted by the termites and/or their gut. A total of 70 bacterial isolates were isolated from the gut of termites obtained from thirteen termite nests in TraOn district, VinhLong province, Mekong Delta, Vietnam. Of the 70 bacterial isolates, 60 (86%) are able to degrade CMC (Carboxyl Methyl Cellulose) after culturing in media containing CMC agar and halo formation after staining with Congo red. Among of them, 5 isolates having high CMC degradation efficiency are chosen to evaluate the potential ability to liberate glucose from cellulose of straw for 5, 10, 15 and 20 days respectively at room temperatures. The results showed that all of the 5 isolates have the cellulose degradation ability and produce the highest glucose contents after 15 days. Out of the 5 isolates, 2 produced glucose in large quantities are 2T1 isolate (0.73 g/L) and 5T6 isolate (0.79 g/L) in hydrolysis solutions. The 2T1, 5T6 strains were 98.99%, 99.01% of identity Paenibacillus humicus strain T20C, Psychrobacter faecalis strain AP3Ka respectively by 16S rRNA genes sequencing and could be potential sources of enzymes for cellulose hydrolysis from cellulosic biomass in future.

Morphological identification of phosphate solubilizing and cellulolytic fungi from mangrove soil under Rhizophora stylosa stands

Mangrove forest is one of the forest ecosystems that can be found in tidal areas. Mangrove forest have ecological, socio-economic benefits for organisms that live in the sea. One of the microorganism that live in mangrove forest is fungus. Therefore, this study aimed to isolate and identify phosphate solubilizing and cellulolytic fungi from mangrove soil. Soil samples were collected from a stands of Rhizophora stylosa in Lubuk Kertang Village, West Brandan District, Langkat Regency, North Sumatra. Soil samples were taken randomly with a dept of 0-20 cm. Isolation of phosphate solubilizing fungi was carried out using Pikovskaya medium and cellulolytic fungi using carboxyl methyl cellulose (CMC) medium. To determine the effectiveness of fungi qualitatively, the phosphate solubility and cellulolytic index were calculated. All isolates obtained were identified morphologically by observing colonies macroscopically and microscopically. This study obtained 12 isolates of phosphate solubilizing and 8 isolates of cellulolytic fungi. Phosphate solubility index ranging from 2.06-2.87 and cellulolytic index of 0.33-3.00. Morphological identifications showed that all isolates of phosphate solubilizing fungi belonged to the genus Aspergillus, while all isolates of cellulolytic fungi belonged to the genus Chaetomium.

Rod-shaped nintedanib nanocrystals improved oral bioavailability through multiple intestinal absorption pathways

Nintedanib (BIBF) is a biopharmaceutical classification system II (BCS II) drug that has a good therapeutic effect for the treatment of nonsmall cell lung cancer; however, it shows poor oral bioavailability due to low dissolution and intestinal absorption. This study aims to fabricate rod-shaped nanocrystals to enhance oral bioavailability by improving the dissolution and absorption of BIBF in the intestine. By prescription screening, BIBF nanocrystals (BIBF-NCs) with a particle size of 325.30 ± 1.03 nm and zeta potential of 32.70 ± 1.24 mV were fabricated by an antisolvent precipitation-ultrasound approach with a stabilizer of sodium carboxyl methyl cellulose (CMC-Na). BIBF-NCs exhibited a rod-shaped morphology by transmission electron microscopy (TEM). The results of powder X-ray diffraction (PXRD) and differential scanning calorimetry (DSC) showed that the crystal form of BIBF in BIBF-NCs was altered. The BIBF-NCs remarkably improved the saturation solubility and dissolution of BIBF compared with BIBF powder. According to the results of in situ single-pass intestinal perfusion (SPIP), BIBF-NCs showed improved absorption and membrane permeability, with Ka and Papp values in the jejunum of 0.21 ± 0.01 min−1 and (4.34 ± 0.11) × 10−4 cm/min, respectively. Further, the Ka and Papp values of BIBF-NCs were all reduced significantly after the addition of inhibitors colchicine, chlorpromazine and indomethacin, which demonstrated that BIBF-NCs could be absorbed by endocytosis mediated by caveolae and clathrin and micropinocytosis in the intestine. The cell evaluation results showed that BIBF-NCs could be taken up by macrophages and transported from Caco-2 monolayers. The in vivo pharmacokinetic results showed that the bioavailability of the BIBF-NCs was 2.51-fold higher than that of the BIBF solution (BIBF-Sol) after oral administration with a longer Tmax (4.50 ± 1.00 h vs. 2.60 ± 1.92 h). In summary, rod-shaped BIBF-NCs could significantly improve oral bioavailability through multiple intestinal absorption pathways.

Proximate Composition of Coated Tomato During Storage

Postharvest loss is one of the major problems militating against all year access to tomato. This study investigated the proximate composition of tomato coated with gelatin, carboxyl methyl cellulose, honey and alkalinized starch, with uncoated tomatoes serving as control. Moisture content, crude protein, ash, crude fat, crude fibre and carbohydrates were determined during storage of tomato at room temperature. Results showed that the control tomato sample kept for 60 days and the moisture content, crude protein, crude fat, ash, and carbohydrates were 94.56, 0.21, 0.04, 0.15 and 4.98%, respectively. The results also showed that tomato coated with gelatine kept till 69 days and the moisture content, crude protein, crude fat, ash and carbohydrates were 91.89, 0.25, 0.07, 0.13 and 7.53%, respectively. The results further showed that tomato coated with carboxyl methyl cellulose kept for 75 days and the moisture content, crude protein, crude fat, ash and carbohydrates were 91.83, 0.12, 0.05, 0.09 and 7.74%, respectively. Results showed that tomato coated with honey kept for 90 days and the moisture content, crude protein, crude fat, ash and carbohydrates were 89.50, 0.10, 0.05, 0.06 and 10.08%, respectively. Results however showed that tomato coated with alkalinized starch kept for 90 days and the moisture content, crude protein, crude fat, ash and carbohydrates were 89.35, 0.17, 0.05, 0.07 and 10.11%, respectively. The study showed that both honey and alkalinized starch were able to preserve retain appreciable amount of nutrients in tomato for additional 30 days.

Chronic toxicity studies of gandhaka rasayana - A herbo-mineral preparation used in Ayurvedic practice

BackgroundGandhaka rasayana (GR) is an important component of many Ayurvedic formulations besides being used as a standalone therapy. However, literature review revealed a chronic toxicity studies with longer duration. ObjectivesTo delineate the safety profile of GR for 180 days administration in rats. Materials and methodsWistar albino rats of both sexes weighing 150 ± 10 g body weight in groups of 20 (10 male and 10 female) for each of the three GR dose levels i.e., 0.54 g, 1.08 g, and 5.4 g/kg were employed. Carboxyl methyl cellulose was administered to the control group in equal volume. Toxicity was assessed based on the changes observed, compared to control, in body weight gain, food and water consumption, organ weight and histopathology, clinical biochemistry, and hematological parameters as per AYUSH guidelines. ResultsGR repeated dose administration caused significant changes in body weight gain, organ ponderal changes, few hematologic and biochemical parameters. Male rats administered with GR at 1.08 g/kg dose showed a significant decrease in the MCV and MCH compared to control, whereas female rat’s administred with 1.08 g/kg and 0.54 g/kg dose showed a significant increase in the MCV and MCH. GR administered at 0.54 g/kg showed a significant increase in the serum glucose level in male rats, whereas female rats showed a significant elevation in the cholesterol level. GR at 0.54 g/kg and 5.4 g/kg showed a significant elevation in the serum SGPT level in male rats. These changes were not observed in female rats. Histological examination revealed mild pathological changes in organs like kidney, liver, spleen and jejunum. ConclusionThe data generated shows that GR is safe and does not have any toxicity potential at the doses used in therapeutics. Some of the changes observed were at higher dose levels which is not likely to be used clinically.

Diradicals or Zwitterions: The Chemical States of m -Benzoquinone and Structural Variation after Storage of Li Ions

Diradicals or Zwitterions: The Chemical States of <i>m</i> -Benzoquinone and Structural Variation after Storage of Li Ions

Analytical study on Fungal Cellulase Produced by Penicillium Expansum grown on Malus Domestica (Apple Fruits)

The rise in world industrialization and the cost of importing enzyme by local industries have led to arise in the search for novel and native enzyme producing microorganisms. Cellulase is an enzyme that catalyzes the breaking down of carbon chains in cellulose and hemicellulose, this research therefore aimed at studying fungal cellulase produced by Penicillium expansum grown on malus domestica (apple fruits). Fresh apple fruit was allowed to deteriorate under laboratory condition until there was visible mould growth. The mould with desired features of the organism of interest was subcultured by direct plating on PDA plates to which 10 % streptomycin has been added to prevent bacterial contaminants. The plates were incubated at 28±2 0C for 7 days until a visible mass of blue mycelia appear. The isolate was further subcultured onto freshly prepared media until pure culture was obtained. Characterization and identification of isolate were done using macroscopy and microscopy techniques. The isolate was re-inoculated into healthy apple fruits and the fruits were incubated at temperature of 28±2 oC for 8 days. Cellulolytic activity was examined every day throughout the incubation period. Crude enzyme was extracted each day using standard methods. Carboxyl methyl cellulose was used as standard for the crude cellulase activity assay after extraction from the infected apple fruits using Dinitrosalicylic acid (DNSA). Culture parameters like pH and temperature were also optimized to determine their effect on cellulolytic activity of the fungus. Cellulase activity was defined as the amount of glucose produced in μmol/mg/min under the assay condition. The highest cellulase activity of 86.84±0.52 μmol/mg/min was observed on day 6 of incubation at 28±2 oC and at pH 7. In conclusion, it is evident from this research that P. expansum isolated could be used as potential novel organism for industrial production of cellulase under optimized fermentation conditions.

Rheological Properties Of (NR/SBR/CMC/C.B) Nanocomposites

This research focuses on the impact of adding materials such as carbon black and polymer of carboxyl methylcellulose on the the rheological properties of styrene butadiene rubber (SBR) and natural rubber (NR) which was studied as a matrix. The present study was a carried out by two groups according to the loading level of carboxyl methylcellulose (CMC) and carbon black(C.B) its molecular weight (N660) which their used as stiffeners in the composites. on the other side, rheometer tests carried according to ASTM D 2705 For the purpose use these composites in various tire making and fender ship. All composites are consisting of carbon black (C.B) N660 (0, 10, 10, 10, 10) pphr and carboxyl methyl cellulose (CMC) (0, 0, 10, 20, 30) pphr respectively for the first group (A) and (0, 20, 20, 20, 20) pphr for C.B, (0, 0, 10, 20, 30) pphr for CMC for the second group (B). The maximum torque, minimum torque, scorch time, viscosity and Tc90 optimum curing time were checked. The results revealed that the parameters differ according to the level of loading. Viscosity, lower torque, maximum torque and optimal curing were reduced for increasing loading ratio of the C.B and CMC. As well, an optimal curing time of the TC90 burning time was reduced as addition ratios of the carbon black (C.B) and carboxyl methyl cellulose (CMC) increased.

Effect of tannic and gallic acid on glycation of egg white protein and formation N-(Carboxyl methyl) lysine

The present study assessed the effect of incorporation of different concentrations of tannic acid (TA) and gallic acid (GA) (0.12, 0.5 and 1%w/v) in heat-treated egg white (EW) protein and glucose (Gl) (120 °C within 20 min) at 3:3% w/w on Carboxyl methyllysine (CML) formation using RP-HPLC and fluorescence detector. TA and GA at concentrations of 0.12 %w/v led to 6-folds decrease in CML content in comparison with EW-Gl where the CML level reached nearly 50 and 42 μg/mL, respectively, after 20 min heating. The evaluation of Maillard reaction products (MRP) formation during the heating process using antioxidant activity and fluorescence intensity tests indicated that there were significant inverse relationships between fluorescence intensity and antioxidant activity in all samples especially at the first minute of the heating process. The result of FTIR and SDS-PAGE confirmed that in the presence of TA and GA, the rate of glycation of protein significantly diminished in comparison with EW-Gl. The level of intercellular reactive oxygen species in Human umbilical vein endothelial cells (HUVEC) using TA and GA-containing samples were lower than when using heat treated EW-Gl samples. Moreover heat-treated TA and GA containing samples showed high antibacterial activities. The results indicated that TA and GA have a good potential in the enhancement of safety heat-treated food products through its antioxidant and antimicrobial activities, and also preventing CML production.

The Effect of Weighting Materials on the Rheological Properties of Iraqi and Commercial Bentonite in Direct Emulsion

Numerous drilling additives and materials are used continuously because they are necessary to support and give the required properties of the drilling fluid so that to ensure the stability of the borehole. This paper aspires to evaluate the rheological properties of bentonite (montmorillonite) Trefawey as an alternative to using commercial bentonite. Monitoring and evaluating of the rheological and filtration properties were prepared. This exertion aims to focus on the effect of hematite, and barite on the rheological properties of the three aforementioned bentonite types. An improvement in the rheological properties of bentonite (montmorillonite). Trefawey was observed after adding the previous heavy materials. Hematite has by some means better ability to improve rheological properties compared to other heavy materials. The emulsifying agent used was Carboxyl Methyl Cellulose (HOCH2COONA), as it has provided excellent results parallel to the lignite. The rheological properties of bentonite (montmorillonite) Trefawey are enhanced by doubling the amount of carboxyl methyl cellulose (HOCH2COONA). The results have proved that the use of weighting materials and emulsifying agent affected the rheological properties of bentonite (montmorillonite) Trefawey in a direct emulsion. The results have shown that it is more appropriate to use carboxyl methyl cellulose as an emulsifying agent to prepare a direct emulsion than bentonite (montmorillonite) Trefawey due to its excellent effect in improving the rheological properties of bentonite (montmorillonite) Trefawey. And it can be said that this effort has succeeded in studying two effects simultaneously. In other words, both heavy substances and emulsifying agent have effects on bentonite (montmorillonite) Trefawey, in order to obtain a stable emulsion and a clearer view of the behavior of Iraqi bentonite. The above effort has focused on making bentonite (montmorillonite) Trefawey suitable for the nature of geological layers such as oil shale, limestone and sandstone. This means preparing drilling fluid using bentonite (montmorillonite) Trefawey to drill the above structures. The study has concluded that it is better to use bentonite (montmorillonite) Trefawey in preparing direct oil emulsions as a stable and successful alternative of imported bentonite.

Electrochemical Fluorination of (Arylthio)methyl Carboxylates and γ-Phenylthio-γ-butyrolactone Derivative

Electrochemical fluorination of various (arylthio)methyl carboxylates was carried out in aprotic organic solvents containing poly(HF) salts to provide the corresponding O-fluoromethyl carboxylates in good to moderate yield. Electrochemical fluorination of a cyclic analogue, a γ-phenylthio-γ-butyrolactone derivative was also achieved under ultrasonication to give the corresponding 4-fluorinated product in moderate yield.

Number of macrophages and transforming growth factor β expression in Citrus limon L. Tlekung peel oil-treated traumatic ulcers in diabetic rats

Purpose: To analyse the potential use of Citrus limon L. Tlekung peel oil in the treatment of traumatic ulcers in diabetic rats based on number of macrophages and transforming growth factor β (TGF-β) expression.&#x0D; Method: Standard steam distillation was performed to produce Citrus limon L. peel oil with its components subsequently analysed by gas chromatography-mass spectrometry (GC-MS). Diabetes was induced with streptozotocin (STZ) via administration of a single 50 mg/kg dose. A traumatic ulcer was subsequently induced with a 5 mm burnisher heated for 30 s and applied without pressure for 1 s to the lower labial mucosa of the animals. Citrus limon L. oil gel containing 3% carboxyl methyl cellulose sodium was then topically administered to the traumatic ulcer for a period of three or five days. TGF-β expression was analysed through immunohistochemical staining and the macrophage number calculated with haematoxylin-eosin stain.&#x0D; Results: The major identified compounds in Citrus limon L. peel oil include fumaric (31.78 %), dlimonene (17.38 %), z-citral (13.55 %), L-linalool (8.51 %), geraniol nerol (3.56 %), geraniol (2.94 %,), αterpineol (1.25 %) and γ-terpinene (1.03 %) together with other minor constituents. Treatment of traumatic ulcers with Citrus limon L peel oil produced higher number of macrophages and TGF-β expression (p = 0.000). Treatment over a period of five days also indicated higher expression of TGF-β and number of macrophages compared to that lasting three days with Citrus limon L peel oil (p = 0.000).&#x0D; Conclusion: Citrus limon L peel oil stimulates TGF-β expression and an increase of macrophage numbers in diabetic subjects during traumatic ulcer healing after three and seven days. Clinical application of Citrus limon L peel oil constitutes a potential therapy in the treatment of traumatic ulcers in diabetic subjects.

Direct catalytic conversion of bagasse fibers to furan building blocks in organic and ionic solvents

The applications of lignocellulosic wastes to produce a wide variety of products, including biochemicals, biomaterials, and biofuels, can be an effective solution for utilizing these valuable waste materials. In this study, the production of furan building blocks from bagasse fibers was investigated by treating unbleached fibers with NMMO, [Bmim]Cl, and TMAH at different temperatures using AlCl3 and CrCl2 as the catalysts. The resulted liquors were extracted with CH2Cl2 to obtain furan rich fraction. Analysis of extracted fractions with GC/MS indicates the production of various furanic compounds due to catalytic solvolysis with different solvents at elevated temperatures. 2(3H)-Furanone and 2-methyl-THF were the main products of catalytic treatment of bagasse fibers with NMMO. Treatment by [Bmim]Cl resulted in 2,5-dihydro furanone as the dominant product at elevated temperatures. Furan carboxylic acid methyl ester and 2,5-furan dicarboxylic acid dimethyl ester were the main TMAH reaction products with unbleached fibers. The results indicate that the type of solvent affects the solvolysis rate and dehydration of cellulose to furanic compounds. Moreover, increasing the temperature led to an increase in the formation of the furanic compounds.Graphical abstract