The increasing development in the computational field that allowed software and hardware advances enables more refined building performance analysis. Simulation-based optimization (SBO) methods allow high standards to be achieved by combining parametric modeling, simulation, and optimization methods. However, SBO methods still need development, especially regarding the correct choice of the optimization algorithm based on the specific characteristics of each problem. This study proposes a multi-objective optimization algorithms benchmark by comparing seven multi-objective optimization algorithms: RBFMOpt, NSGA2, MHACO, NSPSO, MOEA/D, HypE, and SPEA2, across nine building-related problems, including thermal, energy, and daylight simulation. The problems varied from 5 to 18 discrete, continuous, and mixed parameters. The objective functions varied between two and three. We used the hypervolume indicator, IGD+, GD+, and EPS + to compare algorithms’ performance and assess the tendency to reduce computational costs. We also performed the Kruskal-Wallis non-parametric test to analyze the impact of multiple runs on the hypervolume indicator. The results showed that RBFMOpt and HypE perform best across all problems. However, RBFMOpt tends to reduce computational costs since the algorithm requires fewer simulations to obtain the best results.