Prediction Accuracy Of Method Research Articles

Prediction Method for Pomegranate Chlorophyll Content Based on Multi-feature Fusion of Unmanned Aerial Vehicle

The aim of this study was to obtain RGB and multispectral images of fruit tree canopy during the flowering period of pomegranate by multispectral unmanned aerial vehicle (UAV) to quickly and accurately predict the chlorophyll content in order to improve the monitoring efficiency of the orchard. A handheld chlorophyll meter was used to obtain the actual chlorophyll values, and image processing techniques were combined to extract parameters such as color features and texture features of the RGB images as well as vegetation index of the multispectral images. A chlorophyll content prediction method based on the support vector regression model and the convolutional neural network model (CNN-Attention) combined with the attention mechanism was established. The results showed that (1) the accuracy of the prediction model was improved by the fusion of RGB image features and multispectral image vegetation index. (2) After model comparison, the CNN-Attention model built under the fused features was the best in chlorophyll content prediction with R2, RE, and RMSE of 0.9699, 0.0052, and 0.6013, respectively.This study provides a more accurate method for fruit tree chlorophyll content prediction using UAVs, which provides a practical reference for orchard management.

An Improved Decline Curve Analysis Method via Ensemble Learning for Shale Gas Reservoirs

As a clean unconventional energy source, shale gas reservoirs are increasingly important globally. Accurate prediction methods for shale gas production capacity can bring significant economic benefits by reducing construction and operating costs. Decline curve analysis (DCA) is an efficient method that uses mathematical formulas to describe production trends with minimal reliance on geological or engineering parameters. However, traditional DCA models often fail to capture the complex production dynamics of shale gas wells, especially in complex environments. To overcome these limitations, this study proposes an Improved DCA method that integrates multiple base empirical DCA models through ensemble learning. By combining the strengths of individual models, it offers a more robust and accurate prediction framework. We evaluated this method using data from 22 shale gas wells in region L, China, comparing it to six traditional DCA models, including Arps and the Logistic Growth Model (LGM). The results show that the Improved DCA model achieved superior performance—with an mean absolute error (MAE) of 0.0660, an mean squared error (MSE) of 0.0272, and an R2 value of 0.9882—and exhibited greater stability across various samples and conditions. This method provides a reliable tool for long-term production forecasting and optimization without extensive geological or engineering information.

Vessel Trajectory Prediction Based on AIS Data: Dual-Path Spatial–Temporal Attention Network with Multi-Attribute Information

With the rapid growth of the global shipping industry, the increasing number of vessels has brought significant challenges to navigation safety and management. Vessel trajectory prediction technology plays a crucial role in route optimization and collision avoidance. However, current prediction methods face limitations when dealing with complex vessel interactions and multi-dimensional attribute information. Most models rely solely on global modeling in the temporal dimension, considering spatial interactions only later, failing to capture dynamic changes in trajectory interactions at different time points. Additionally, these methods do not fully utilize the multi-attribute information in AIS data, and the simple concatenation of attributes limits the model’s potential. To address these issues, this paper proposes a dual spacial–temporal attention network with multi-attribute information (DualSTMA). This network models vessel behavior and interactions through two distinct paths, comprehensively considering individual vessel intentions and dynamic interactions. Moreover, we divide vessel attributes into dynamic and static categories, with dynamic attributes fused during feature preprocessing, and with static attributes being controlled through a gating mechanism during spatial interactions to regulate the importance of neighboring vessel features. Benchmark tests on real AIS data show that DualSTMA significantly outperforms existing methods in prediction accuracy. Ablation studies and visual analyses further validate the model’s reliability and advantages.

Benchmark Investigation of SARS-CoV-2 Mutants' Immune Escape with 2B04 Murine Antibody: A Step Towards Unraveling a Larger Picture.

Even though COVID-19 is no longer the primary focus of the global scientific community, its high mutation rate (nearly 30 substitutions per year) poses a threat of a potential comeback. Effective vaccines have been developed and administered to the population, ending the pandemic. Nonetheless, reinfection by newly emerging subvariants, particularly the latest JN.1 strain, remains common. The rapid mutation of this virus demands a fast response from the scientific community in case of an emergency. While the immune escape of earlier variants was extensively investigated, one still needs a comprehensive understanding of how specific mutations, especially in the newest subvariants, influence the antigenic escape of the pathogen. Here, we tested comprehensive in silico approaches to identify methods for fast and accurate prediction of antibody neutralization by various mutants. As a benchmark, we modeled the complexes of the murine antibody 2B04, which neutralizes infection by preventing the SARS-CoV-2 spike glycoprotein's association with angiotensin-converting enzyme (ACE2). Complexes with the wild-type, B.1.1.7 Alpha, and B.1.427/429 Epsilon SARS-CoV-2 variants were used as positive controls, while complexes with the B.1.351 Beta, P.1 Gamma, B.1.617.2 Delta, B.1.617.1 Kappa, BA.1 Omicron, and the newest JN.1 Omicron variants were used as decoys. Three essentially different algorithms were employed: forced placement based on a template, followed by two steps of extended molecular dynamics simulations; protein-protein docking utilizing PIPER (an FFT-based method extended for use with pairwise interaction potentials); and the AlphaFold 3.0 model for complex structure prediction. Homology modeling was used to assess the 3D structure of the newly emerged JN.1 Omicron subvariant, whose crystallographic structure is not yet available in the Protein Database. After a careful comparison of these three approaches, we were able to identify the pros and cons of each method. Protein-protein docking yielded two false-positive results, while manual placement reinforced by molecular dynamics produced one false positive and one false negative. In contrast, AlphaFold resulted in only one doubtful result and a higher overall accuracy-to-time ratio. The reasons for inaccuracies and potential pitfalls of various approaches are carefully explained. In addition to a comparative analysis of methods, some mechanisms of immune escape are elucidated herein. This provides a critical foundation for improving the predictive accuracy of vaccine efficacy against new viral subvariants, introducing accurate methodologies, and pinpointing potential challenges.

Deep generative design of RNA aptamers using structural predictions.

RNAs represent a class of programmable biomolecules capable of performing diverse biological functions. Recent studies have developed accurate RNA three-dimensional structure prediction methods, which may enable new RNAs to be designed in a structure-guided manner. Here, we develop a structure-to-sequence deep learning platform for the de novo generative design of RNA aptamers. We show that our approach can design RNA aptamers that are predicted to be structurally similar, yet sequence dissimilar, to known light-up aptamers that fluoresce in the presence of small molecules. We experimentally validate several generated RNA aptamers to have fluorescent activity, show that these aptamers can be optimized for activity in silico, and find that they exhibit a mechanism of fluorescence similar to that of known light-up aptamers. Our results demonstrate how structural predictions can guide the targeted and resource-efficient design of new RNA sequences.

SPLENDID incorporates continuous genetic ancestry in biobank-scale data to improve polygenic risk prediction across diverse populations.

Polygenic risk scores are widely used in disease risk stratification, but their accuracy varies across diverse populations. Recent methods large-scale leverage multi-ancestry data to improve accuracy in under-represented populations but require labelling individuals by ancestry for prediction. This poses challenges for practical use, as clinical practices are typically not based on ancestry. We propose SPLENDID, a novel penalized regression framework for diverse biobank-scale data. Our method utilizes ancestry principal component interactions to model genetic ancestry as a continuum within a single prediction model for all ancestries, eliminating the need for discrete labels. In extensive simulations and analyses of 9 traits from the All of Us Research Program (N=224,364) and UK Biobank (N=340,140), SPLENDID significantly outperformed existing methods in prediction accuracy and model sparsity. By directly incorporating continuous genetic ancestry in model training, SPLENDID stands as a valuable tool for robust risk prediction across diverse populations and fairer clinical implementation.

Traffic Flow Prediction: A Method Using Bagging-Based Ensemble Learning Model

For the development of the national economy, transportation is strategically significant. As the increasing ownership of automobiles, traffic jams are a common occurrence. Accurate prediction of traffic flow contributes to diverting traffic effectively and improving the quality of urban traffic, in turn improving the operation of the overall transportation system. The rapid development of artificial intelligence technologies, especially machine learning and deep learning, has provided effective methods for accurate prediction of traffic flow. Based on the above, in order to improve the accuracy of the prediction and to extend the application of machine learning and deep learning in the prediction of traffic flow, this study proposed a bagging-based ensemble learning model. Firstly, normalization method is used to preprocess the data. Subsequently, base prediction models including decision tree, random forest, logistic regression, convolution neural network, long short-term memory and multilayer perceptron are selected for training the prediction model, respectively. Finally, bagging-based ensemble learning method is used to integrate these base prediction models to further predict traffic flow. The results of comparison between the single base prediction models and the bagging-based ensemble learning model on the five evaluation indicators show that, for predicting the traffic flow, the bagging-based ensemble learning model outperforms the base prediction models. Meanwhile, this study explores the potential in the application of machine learning, deep learning, and especially bagging-based ensemble learning to predict traffic flow.

Thermo-hydraulic performance of concentric tube heat exchangers with turbulent flow: Predictive correlations and iterative methods for pumping power and heat transfer

This research addresses the problem of predicting the thermo-hydraulic performance of concentric tube heat exchangers (CTHE) under turbulent flow conditions, a critical aspect in energy-efficient industrial systems such as HVAC, power generation, and chemical processing. Existing studies often lack accurate predictive methods for balancing heat transfer performance with pumping power requirements. To tackle this issue, novel correlations and an iterative Newton–Raphson method were developed for predicting pumping power and heat transfer rates. Three-dimensional CFD simulations of a water-to-water counter-flow CTHE were conducted, with Reynolds numbers ranging from 4000 to 8000 for both the hot and cold fluids. The simulations employed the Reynolds-Averaged Navier–Stokes (RANS) equations with the k−ω SST turbulence model. The results demonstrated that increasing the Reynolds number enhances both heat transfer rates and pumping power, with the cold fluid requiring consistently higher pumping power. New correlations were developed to predict pumping power, capturing the impact of both entry and fully developed flow regions. These correlations showed an average error of less than 2.33% when compared with the CFD data. The iterative Newton–Raphson method for predicting heat transfer rates demonstrated high accuracy, with an average error of 0.66% for heat transfer rate, 0.03% for hot fluid outlet temperature, and 0.01% for cold fluid outlet temperature. Additionally, we identified optimal operating conditions for efficient cooling and heating based on the heat capacity ratio (Cr). The novelty of this work lies in the development of new, highly accurate predictive correlations and iterative methods for optimizing CTHE performance, going beyond existing literature by providing comprehensive insights into the relationship between pumping power, heat transfer efficiency, and flow conditions.

Fragmentomics of plasma mitochondrial and nuclear DNA inform prognosis in COVID-19 patients with critical symptoms

BackgroundThe mortality rate of COVID-19 patients with critical symptoms is reported to be 40.5%. Early identification of patients with poor progression in the critical cohort is essential to timely clinical intervention and reduction of mortality. Although older age, chronic diseases, have been recognized as risk factors for COVID-19 mortality, we still lack an accurate prediction method for every patient. This study aimed to delve into the cell-free DNA fragmentomics of critically ill patients, and develop new promising biomarkers for identifying the patients with high mortality risk.MethodsWe utilized whole genome sequencing on the plasma cell-free DNA (cfDNA) from 33 COVID-19 patients with critical symptoms, whose outcomes were classified as survival (n = 16) and death (n = 17). Mitochondrial DNA (mtDNA) abundance and fragmentomic properties of cfDNA, including size profiles, ends motif and promoter coverages were interrogated and compared between survival and death groups.ResultsSignificantly decreased abundance (~ 76% reduction) and dramatically shorter fragment size of cell-free mtDNA were observed in deceased patients. Likewise, the deceased patients exhibited distinct end-motif patterns of cfDNA with an enhanced preference for “CC” started motifs, which are related to the activity of nuclease DNASE1L3. Several dysregulated genes involved in the COVID-19 progression-related pathways were further inferred from promoter coverages. These informative cfDNA features enabled a high PPV of 83.3% in predicting deceased patients in the critical cohort.ConclusionThe dysregulated biological processes observed in COVID-19 patients with fatal outcomes may contribute to abnormal release and modifications of plasma cfDNA. Our findings provided the feasibility of plasma cfDNA as a promising biomarker in the prognosis prediction in critically ill COVID-19 patients in clinical practice.

Operation prediction of open sun drying based on mathematical-physical model, drying kinetics and machine learning

In order to determine the moisture ratio of dried material whether the storage requirements are met, it was crucial to find an accurate prediction and convenient method in the open sun drying process. Therefore, the mathematical-physical model, drying dynamics model and machine learning methods were employed and compared in this study. The machine learning methods were first applied to predict the moisture ratio change of sweet potato during open sun drying. A large number of sweet potatoes drying experiments were carried out under open sun drying for theoretical analysis. The results shown that the drying kinetic model of sweet potato was also different under different drying climate conditions. The heat and mass transfer model of sweet potato was established and validated with R2 0.8990 and RMSE 0.0826. Different optimal machine learning prediction methods have be selected based on statistical metrics. Finaly, the machine learning prediction method was considered to be superior to the mathematical-physical model and the drying kinetic model in predicting moisture ratio. The results of this study can be analogized to drying process control of other agricultural products in the future.

Prediction and classification of obesity risk based on a hybrid metaheuristic machine learning approach.

As the global prevalence of obesity continues to rise, it has become a major public health concern requiring more accurate prediction methods. Traditional regression models often fail to capture the complex interactions between genetic, environmental, and behavioral factors contributing to obesity. This study explores the potential of machine-learning techniques to improve obesity risk prediction. Various supervised learning algorithms, including the novel ANN-PSO hybrid model, were applied following comprehensive data preprocessing and evaluation. The proposed ANN-PSO model achieved a remarkable accuracy rate of 92%, outperforming traditional regression methods. SHAP was employed to analyze feature importance, offering deeper insights into the influence of various factors on obesity risk. The findings highlight the transformative role of advanced machine-learning models in public health research, offering a pathway for personalized healthcare interventions. By providing detailed obesity risk profiles, these models enable healthcare providers to tailor prevention and treatment strategies to individual needs. The results underscore the need to integrate innovative machine-learning approaches into global public health efforts to combat the growing obesity epidemic.

Empirical investigation of a data analytics model in medical settings

This article centers around the development and analysis of machine learning and deep learning models aimed at enhancing diabetes diagnosis. In the swiftly evolving landscape of data technologies, it becomes crucial to explore the applications of these methods for accurate predictions and improved medical decision-making. Our research encompasses diverse datasets, leveraging state-of-the-art algorithms and technologies for model training and testing. The primary emphasis lies in evaluating the accuracy, sensitivity, and specificity of models within the realm of diabetes diagnosis. The study results reveal significant advancements in disease prediction, underscoring the potential of machine learning and deep learning in medical applications. This work introduces fresh perspectives on the utilization of computational methods in healthcare and serves as a foundation for prospective research in this domain.

Machine learning-based surrogate models for fast impact assessment of a new building on urban local microclimate at design stage

The rapid urbanization introduces changes in the local urban microclimate. Many efforts have been paid on the impact assessment of building design on local microclimate. However, there is still a lack of efficient and accurate prediction method for assessing the impacts on local microclimate when making the design of individual buildings. Two complementary machine learning-based surrogate models are proposed, including an SVR-based local air temperature model and a LightGBM-based local wind velocity model. They are identified by evaluating and comparing eight alternative machine learning models, four for each model development. 200 sets of CFD simulation data corresponding to different building designs are used for the model training and validation. The results show that the developed surrogate models can dramatically reduce computation time (from over 5 h to less than a second for a single prediction) while keeping the same order of accuracy of CFD simulations for local microclimate prediction of individual buildings. It therefore facilitates the fast, comprehensive and accurate prediction of the impacts on the local microclimate at the early design stage of new construction and renovation of individual buildings, for designers to deliver preferred local microclimate and/or avoid unacceptable microclimate changes.

OligoFormer: an accurate and robust prediction method for siRNA design.

RNA interference (RNAi) has become a widely used experimental approach for post-transcriptional regulation and is increasingly showing its potential as future targeted drugs. However, the prediction of highly efficient siRNAs (small interfering RNAs) is still hindered by dataset biases, the inadequacy of prediction methods, and the presence of off-target effects. To overcome these limitations, we propose an accurate and robust prediction method, OligoFormer, for siRNA design. OligoFormer comprises three different modules including thermodynamic calculation, RNA-FM module, and Oligo encoder. Oligo encoder is the core module based on the transformer encoder. Taking siRNA and mRNA sequences as input, OligoFormer can obtain thermodynamic parameters, RNA-FM embedding, and Oligo embedding through these three modules, respectively. We carefully benchmarked OligoFormer against six comparable methods on siRNA efficacy datasets. OligoFormer outperforms all the other methods, with an average improvement of 9% in AUC, 6.6% in PRC, 9.8% in F1 score, and 5.1% in PCC compared to the best method among them in our inter-dataset validation. We also provide a comprehensive pipeline with prediction of siRNA efficacy and off-target effects using PITA score and TargetScan score. The ablation study shows RNA-FM module and thermodynamic parameters improved the performance and accelerated convergence of OligoFormer. The saliency maps by gradient backpropagation and base preference maps show certain base preferences in initial and terminal region of siRNAs. The source code of OligoFormer is freely available on GitHub at: https://github.com/lulab/OligoFormer. Docker image of OligoFormer is freely available on the docker hub at https://hub.docker.com/r/yilanbai/oligoformer.

Assessment of Additive Manufactured Micro-Channel Characteristics: Impact of Hydraulic Diameter Evaluation

Abstract Among internal cooling techniques for gas turbines components, skin cooling is recognized as one of the most promising, especially thanks to the spread of additive manufacturing techniques. In this regard, several studies have tried to characterize heat transfer and pressure loss performance of additive manufactured micro-channels, as well as the impact of AM characteristic parameters, mainly in the form of building angle, and resulting surface roughness and channel shape. The open literature offers several correlations in terms of friction and heat transfer coefficient using a representative hydraulic diameter. Despite that, little attention is given on the importance of such characteristic length definition which may lead to under/over estimation of the cooling rates when correlations are used in the design In this work, coupons featuring circular micro-channelswith diameters of 0.5 and 1 mm and different building angles have been tested, to retrieve pressure losses and an average heat transfer coefficient through a lumped approach. The coupons were additive manufactured using the Laser Powder Bed Fusion (L-PBF) technique. Exploiting the experimental survey, the impact of the considered hydraulic diameter was investigated, by comparing different approaches based on a direct measurement. An additional and new approach, aimed at the identification of an “effective” diameter, based on fluid-dynamic considerations, was also considered. The data correlation and the comparison with available correlations from different authors showed the newly proposed approach to provide superior scaling capabilities and, in turn, allowing for the development of more accurate prediction methods

An optimal goose lithium-ion batteries accurate and rapid RUL prediction method with automatic initial hyperparameters settings

Abstract Machine learning has emerged as a highly effective tool for addressing complex data problems, garnering significant attention in the field of equipment degradation and remaining service life prediction. Existing prediction models typically exhibit two primary shortcomings: on the one hand, the accuracy of life prediction reaches the desired level of precision while failing to achieve a sufficiently fast prediction speed, and on the other hand, generalization is not guaranteed while requiring the model to be robust. These two aspects present a significant challenge to the field of machine learning. In light of the aforementioned issues, we propose a prediction model based on the goose algorithm. Initially, we set the goose algorithm using adaptive initialization of the goose population to guarantee that the goose population is set at the appropriate interval, and we incorporate it into the extreme learning machine model through the improved goose algorithm. goose algorithm is used to predict the service life. Finally, we utilize different types of lithium batteries with varying operational conditions to conduct pertinent case studies to validate the proposed prediction model. The results demonstrated that the average accuracy was above 98% in all validated datasets. The shortest computation time was 0.19 s.

Pantograph fault prediction of urban rail transit vehicles based on edge feature extraction and detection

Nowadays, as an indispensable part of urban infrastructure, urban rail transit (URT) vehicles have also developed rapidly. A large amount of manpower, material resources, and financial resources need to be invested in the construction process of URT. For URT vehicles, research on more accurate fault prediction methods can save a lot of maintenance costs and improve the reliability of URT construction. As an important electrical equipment for urban rail transit vehicles to obtain electric energy from the catenary, the operation of rail transit vehicles puts forward higher performance requirements for the pantograph. For solving the problems of low accuracy of fault prediction, over reliance on practical experience and high cost of fault prediction in the application of traditional URT vehicle pantograph fault prediction model. Combining sensor network and artificial intelligence algorithm, this paper analyzed the traditional rail transit vehicle pantograph fault prediction model, and verified it through comparative experiments. Through the comparative analysis of the experimental results, this paper can draw a conclusion that compared with the traditional rail transit vehicle pantograph fault prediction model, the rail transit vehicle pantograph fault prediction model has higher fault prediction accuracy, less model response time, lower risk of pantograph failure, higher model application satisfaction, and the accuracy of fault prediction increased by about 6.6%. The rail transit vehicle pantograph fault prediction model can effectively improve the accuracy of vehicle pantograph fault prediction, which can greatly promote the safety of URT and promote the intelligent process of URT.

Long Short-Term Memory and Gated Recurrent Unit Modeling for Stock Price Forecasting

The rapid advancement of deep learning technology offers significant benefits, particularly for time series data forecasting. LSTM and GRU are two deep learning methods used for forecasting. This study aims to compare the LSTM and GRU methods in predicting the stock prices of PT Mayora Indah Tbk, listed on the Indonesia Stock Exchange (IDX), accessed through Yahoo Finance. The model architecture was developed using combinations of data splitting, learning rate, epoch count, and neuron count. The combinations used in this study include data splits of 70:30 and 80:20, with varying parameter combinations of learning rates at 0.01, 0.001, and 0.0001, epoch counts of 50, 100, and 150, and neuron counts of 50 and 100. The results indicate that the GRU method outperforms the LSTM method in prediction accuracy. The RMSE and MAPE tests show that the GRU method yields RMSE and MAPE of 34.4233 and 1.27%, respectively, compared to the LSTM method with RMSE and MAPE of 35.3775 and 1.28%. The best GRU architecture was achieved with a learning rate of 0.001, 50 neurons, and 150 epochs, while the best LSTM architecture was achieved with a learning rate of 0.001, 100 neurons, and 150 epochs. The optimal architecture for both methods was found with a data split of 70:30

Improving embedding-based link prediction performance using clustering

Incomplete knowledge graphs are common problem that can impair task accuracy. As knowledge graphs grow extensively, the probability of incompleteness increases. Link prediction addresses this problem, but accurate and efficient link prediction methods are needed to handle incomplete and extensive knowledge graphs. This study proposed modifications to the embedding-based link prediction using clustering to improve performance. The proposed method involves four main processes: embedding, clustering, determining clusters, and scoring. Embedding converts entities and relations into vectors while clustering groups these vectors. Selected clusters are determined based on the shortest distance between the centroid and the incomplete knowledge graph. Scoring measures relation rankings, and link prediction result is selected based on highest scores. The link prediction performance is evaluated using Hits@1, Mean Rank, Mean Reciprocal Rank and prediction time on three knowledge graph datasets: WN11, WN18RR, and FB13. The link prediction methods used are TransE and ComplEx, with BIRCH as the clustering technique and Mahalanobis for short-distance measurement. The proposed method significantly improves link prediction performance, achieving accuracy up to 98% and reducing prediction time by 99%. This study provides effective and efficient solution for improving link prediction, demonstrating high accuracy and efficiency in handling incomplete and extensive knowledge graphs.

Local buckling behaviour of web perforated cold-formed steel lipped channel columns

To connect beams and bracings with storage rack uprights, closely spaced perforations are provided along the web, flanges, and rear flanges of uprights. These perforations can significantly lower the ultimate capacity of such compression members with the possible influence of its natural buckling modes. This capacity reduction can depend on various parameters such as (a) geometrical shape, proportioning of cross-section, and stiffeners; (b) perforation shape, size, spacing, and location; (b) slenderness of member, cross-section, and elements of cross-section; and (d) material properties. A thorough understanding of the influence of the above-mentioned factors is necessary for the accurate strength prediction of perforated Cold-formed steel (CFS) compression members. Even though the current design standards are updated for the accurate strength prediction of unperforated CFS compression members, they do not collectively account for the influence of all the aforementioned factors on the load-carrying capacity of the perforated CFS members, particularly for the local buckling capacity. Though the Direct Strength Method (DSM) of design is the most accepted method for accurate strength prediction of CFS members even for complex cross-sectional shapes, recent research on the strength evaluation of perforated CFS members using DSM has emphasized the need for refinement in DSM. The Modified Direct Strength Method (MDSM), which accounts for the simultaneous buckling of flanges and web, includes the cross-section aspect ratio and cross-section slenderness to predict more accurately the local buckling design strength. However, it was developed only for unperforated specimens. Hence, a systematic experimental and numerical investigation was done to understand the influence of the perforation in the local buckling behavior of the lipped channel section. In total, 14 specimens, including 2 unperforated and 12 web perforated CFS lipped channel stub columns were physically tested with fixed support conditions. The Finite Element Analysis using ABAQUS software was used to conduct an extensive parametric numerical study. The results were used to compare the strength curves of DSM and MDSM and the modification in the design curves has been proposed by considering the erosion in strength due to the presence of perforation.