Professional YouTubers are developing a new culture through which they stage health content in pervasive ways. The present article aims to provide a methodological approach to analyse this type of content by adopting a critical perspective in health psychology. To achieve this, we first define our theoretical framework. Second, we formulate a multi-method design combining narrative and visual analyses, as well as automatised linguistic procedures. We then illustrate the potential of our methodology through concrete examples. Implications of this methodology in health psychology are discussed with regard to healthism, a dominant contemporary trend that strongly values the individualised pursuit of health. • Multi-method design in critical health psychology on lifestyle YouTubers' videos. • Targeting YouTubers' staged health practices within the contemporary media culture. • Recommendations on ethical and practical challenges raised by YouTube's affordances. • Methodological design including narrative, visual, and automatised analyses. • Illustrations of analyses and interpretations of YouTubers' health video content.