The Hemlo AuMo deposit, in the Superior Province of the Canadian Shield, is composed mainly of metamorphosed, metasomatized and intensely deformed volcano-sedimentary rocks. The ore consists dominantly of microclinized rocks and pyrite-sericite ± biotite schists with disseminated Au, molybdenite and a variety of other minerals. UPb zircon data presented in the companion paper indicate the occurrence of at least two periods of volcanism at 2772 and 2695 Ma, and three main generations of granitoid plutons, the most widespread phase forming at ∼ 2684–2688 Ma. UPb data for titanite, rutile and monazite presented here show that the rocks within and adjacent to the Hemlo deposit experienced protracted metamorphic and hydrothermal activity postdating the bulk of the magmatism. Titanite ages of 2676–2678 Ma from granodiorite units proximal to, but outside of the deposit, are interpreted as dating amphibolite-facies metamorphism which correlates with the zircon and titanite age of intrusion of the late-tectonic Gowan Lake Pluton. Titanite from schists and dikes within the deposit is uniformly 2670–2672 Ma old, which probably reflects a phase of lower-grade metamorphism and metasomatism that affected the deposit but not its surroundings. Structural and petrographic evidence suggests that these phases of medium- and subsequent lower-grade metamorphism correlate with early and late phases of dextral shearing (F 3) . Rutile and monazite were observed only in a variety of altered units within the Hemlo deposit. Rutile coexists, in part, with titanite but yields much younger ages: 2632 ± 5, 2632 ± 3 and 2635 ± 14 Ma in adjacent outcrops of the Page-Williams Property, 2641± 4 Ma in a drill-core sample of the same property, and a combined rutile-monazite age of 2645 ± 4 Ma at a different location within the Golden Sceptre Property. These rutile and monazite ages are interpreted as reflecting low-grade hydrothermal activity probably accompanied by episodic deformation and dynamic recrystallization; this protracted activity is thought to be the expression of magmatic and related metamorphic processes in the lower crust. The geological record suggests that the most active period of alteration and hence, likely, mineralization, occurred sometime from the medium- to the low-grade metamorphic phases which correlate with early and late stages of dextral shearing, respectively, between ∼2680 and ∼2670 Ma ago. The role of the younger (2630–2650 Ma) hydrothermal activity with respect to mineralization is not completely understood. PbPb data, mostly on K-feldspar, indicate relatively uniform isotopic compositions for a variety of rocks inside and outside the deposit. The 207 Pb 204 Pb ratios are relatively non-radiogenic, indicating that the bulk of the rocks and the mineralizing fluids were derived from juvenile crust and/or from the mantle without significant involvement of much older (pre-2800 Ma) crust.