This paper investigated the quasi-static and dynamic behavior of 3D auxetic metamaterial structures made from carbon fiber reinforced polymer (CFRP) laminated composite. The aim of the study was to enhance design methodologies for load-bearing and energy absorption applications of these 3D novel structures, filling the research gap in understanding their response to quasi-static and especially dynamic loadings. The two novel 3D structures were designed and fabricated by using an interlocking assembly method based on the 2D auxetic CFRP sheets, which were formed with hybrid double-arrow-head with re-entrant and star unit-cells and made with plain weave carbon epoxy prepregs. The finite element (FE) method was adopted to analyze the mechanical characteristics of the structures under the quasi-static and dynamic loading, and Hashin failure criteria were used to define damage in the structures. The study showed that the designed 3D auxetic CFRP structures simultaneously exhibit superior auxeticity, load-bearing, and energy absorption capacity.