Advanced sensing equipment exhibits high sensitivity and reliability in detecting food additives, enabling the practical assessment of the safety of processed foods. Currently, chemical detection methods are commonly utilized for identifying food additives. However, these approaches tend to be intricate and time-consuming. In this study, we designed and fabricated an integrated terahertz microfluidic sensor, which achieves high sensitivity by incorporating a metasurface within the microfluidic chip. The metasurface comprises metal wires and split-ring resonators, with three optional sensing sites within the frequency domain of 0.1–1.2 THz, thereby enhancing the reliability of the sensor. Additionally, the use of a self-injection micropump improves the stability of the liquid flow rate, preventing experimental errors caused by manual injection. Utilizing this sensor, we conducted concentration sensing experiments on potassium sorbate and sodium benzoate solutions, successfully identifying sugar-containing and sugar-substituted beverages with high sensitivity and rapid sensing speed. The average sensitivity of the sensor is 152.8 GHz·RIU−1. The results of this study provide a feasible method for the development of microfluidic metasurface sensors.