A field experiment was conducted at Chandra Shekhar Azad University of Agriculture and Technology, Kanpur during Kharif season of 2021, to evaluate effect of different doses of Mesotrione 2.27% w/w + Atrazine 22.7% w/w SC on growth and yield of maize (Zea mays L.). The experiment was laid down in the Randomized block design with ten treatments which was replicated three times. At 45, 60 and 90 DAS among different herbicidal treatments maximum plant height was observed in Mesotrione 2.27% w/w + Atrazine 22.7% w/w SC) @ 1.0 kg a.i. ha-1. Among the herbicidal treatments, highest cob length (15.67 cm), grain rows per cob (13.26), grains per row (26.93) and grains per cob (370.83) was observed in the treatment T4 (Mesotrione 2.27% w/w + Atrazine 22.7% w/w SC) @ 1.0 kg a.i. ha-1) followed by treatment T3 (Mesotrione 2.27% w/w + Atrazine 22.7% w/w SC) @ 0.875 kg a.i. ha-1). Data from experiment revealed that significantly highest grain yield was recorded in weed free plot (35.65 q ha-1). While among herbicidal treatments, application of Mesotrione 2.27% w/w + Atrazine 22.7% w/w SC @ 1.0 kg a.i. ha-1 (35.18) resulted in significantly higher grain yield followed by (T3) Mesotrione 2.27% w/w + Atrazine 22.7% w/w SC @ 0.875 kg a.i. ha-1 (34.38 q ha-1). Among all the treatments all the parameters of crop growth and yield was highest in the weed free treatment (T9).