Mental Well-being Of Patients Research Articles

Quality of Life in Patients with Hyperthyroidism: Where do we stand?

Introduction. Increasing interest exists concerning the physical and mental wellbeing of patients with hyperthyroidism. Aim. This review aims at gathering the most updated literature on the quality of life (QoL) in patients with hyperthyroidism. Method: We searched PubMed from inception to May 20, 2020 for English language studies using the following entries: “hyperthyroidism AND quality of life”, “Graves’ disease AND quality of life”, “diffuse toxic goiter AND quality of life”, “toxic nodular goiter AND quality of life”, “subclinical hyperthyroidism AND quality of life”. Thirty-nine papers were finally reviewed. Results: Patients with hyperthyroidism have worse QoL than euthyroid subjects, especially if they have Graves’ disease and Graves’ orbitopathy. Treatment of hyperthyroidism with restoration of euthyroidism may not fully restore QoL even after many years, indicating that such patients have difficulties adapting to and coping with their illness, thus experiencing marked and longstanding limitations in physical, mental and psychosocial functioning. Conclusion. As differences exist on long-term outcomes between therapeutic options for hyperthyroidism, it is logical to hypothesize related differences in long-term changes in QoL. Future clinical and psychological studies could monitor QoL and its related domains across different stages of disease and deepen patients’ trajectories of illness experience and the use of coping strategies to face their condition.

Effect of Exercise on Quality of Life in Parkinson's Disease: A Systematic Review and Meta-Analysis.

Background Exercise has an integral impact on the physical and mental wellbeing of patients with Parkinson's disease (PD), yet no comprehensive and quantitative analysis has been conducted on the effect of exercise on quality of life (QoL) in these patients. This study aimed to evaluate the effect of exercise on overall QoL and different domains of QoL in people with PD, as well as investigating the influence of factors such as the exercise type and intervention period. Methods Databases, such as PubMed, Embase, and Cochrane Central Register of Controlled Trials, were searched since inception to August 14, 2018 to identify randomized controlled trials that compare the effect of exercise versus no intervention on QoL in PD patients. Following the subgroup analysis, heterogeneity was further explored. The quality of eligible studies was assessed according to PRISMA guidelines. Results 20 studies were included with 1,143 participants in total. A meta-analysis showed a significant improvement in QoL after exercise intervention in PD patients (SMD = −0.24, 95% CI = −0.36 to −0.12, P < 0.001). A subgroup analysis of exercise types revealed significant QoL improvement with aerobic exercise, martial arts, and dance, but not anaerobic exercise and combined exercise. Interventions lasting 12 weeks or longer improved QoL significantly. Conclusions Exercise interventions, especially aerobic exercise, dance, and Tai Chi, significantly improve QoL in PD patients. At least 12 weeks of exercise is needed to bring about significant benefits.

Is there an association between serum 25(OH)D3 and mental well-being in patients with type 2 diabetes? Results from a cohort study in primary care

PurposeThere are limited and inconsistent results on the correlation between vitamin D and mental health in patients with type 2 diabetes (T2D). Thus, our aim was to explore the association between vitamin D and mental well-being in a community-based sample of participants with T2D.MethodsWe analyzed serum 25-hydroxyvitamin D3 (25(OH)D3) in 698 patients with T2D at the baseline examination. The cohort was reinvestigated after 4 years. Data from SF-36 questionnaires measuring vitality and mental health at baseline and after 4 years were used for analyses.ResultsSerum 25(OH)D3 was inversely associated with poor mental health at baseline (odds ratio (OR) for 10 nmol/l increase in 25(OH)D3, 0.90 (95% confidence interval (CI) 0.83–0.96, p = 0.003)) but not at follow-up (p > 0.05). Serum 25(OH)D3 was not associated with vitality at baseline (p > 0.05). At follow-up, there was an inverse association between 25(OH)D3 and low vitality (OR for 10 nmol/l increase in 25(OH)D3, 0.89 (95% CI 0.82–0.97, p = 0.009)) but not after adjustment.ConclusionWe found an inverse association between 25(OH)D3 and mental health in patients with T2D at baseline. We found no association between 25(OH)D3 and vitality after adjustment. Future studies are needed to determine the association between vitamin D and mental well-being in patients with T2D.

Newborn with incarcerated inguinal hernia and complete androgen insensitivity syndrome

Abstract Disorders of sex development represent a large and heterogeneous group of diseases that have an important impact on physical and mental well-being of patients and their families. An early diagnosis and a multidisciplinary approach are fundamental to guarantee the highest standard of care.

The Impact of Laughter Yoga on Mental Well-being of Cancer Patients under Chemotherapy

Background: It is generally accepted thatcancer affects the concept of mental well-being by changing the physical, psychological, spiritual, and social dimensions of the patient's life. Laughter yoga as one of the complementary therapies may promote mental well-being in patients undergoing chemotherapy. Aim: This study aimed to determine the effect of laughter yoga on the mental well-being of cancer patients undergoing chemotherapy. Method: This randomized controlled trial was conducted on 69 cancer patients undergoing chemotherapy at Reza Medical Center, Mashhad, Iran, in 2018. The intervention group was subjected to four 20-30 min sessions of laughter yoga prior to chemotherapy. On the other hand, the control group received routine self-care training. The mental well-being scores were measured using the Warwick-Edinburgh Mental Well-being Scale (WEMWBS) before and after the laughter yoga sessions. Data were analyzed in SPSS software (version 20) using an independent t-test, Mann-Whitney test, Wilcoxon test, and repeated measures ANOVA. Results: According to the results,the mean age values of the patients were 49.0±9.6 and 45.2±12.6 years in the intervention and control groups, respectively. Regarding the independent t-test results, the mean post-test WEMWBS score in the intervention group (50.0±8.9) was significantly higher than that in the control group (47.9±10.4, P=0.004). Moreover, the repeated measures ANOVA showed a significant increase in the mean post-test WEMWBS score in the intervention group (P<0.001). Implications for Practice: Laughter yoga can promote the mental well-being of patients undergoing chemotherapy; therefore, its clinical applications are recommended in this study.

Green exercise and mg-ca-SO4 thermal balneotherapy for the treatment of non-specific chronic low back pain: a randomized controlled clinical trial

BackgroundNon-specific chronic low back pain (nscLBP) has a high socio-economic relevance due to its high incidence, prevalence and associated costs. Therefore, it is essential to evaluate effective therapeutic strategies. This study examines the effects of moderate mountain exercise and spa therapy on orthopedic and psychophysiological parameters. Based on a three-armed randomized controlled trial, guided mountain hiking tours and balneotherapy in thermal water were compared to a control group.MethodsEighty patients with diagnosed nscLBP were separated into three groups: The two intervention groups GE (green exercise) and GEBT (green exercise and balneotherapy) undertook daily mountain hiking tours, whereas the GEBT group got an additional treatment with baths in Mg-Ca-SO4 thermal water. The third group (CO) received no intervention. GE and GEBT group were treated for 6 days; all groups were followed up for 120 days.ResultsCompared to GE and CO group, the GEBT treatment showed significant improvements of pain, some orthopedic parameters, health-related quality of life and mental well-being in patients with nscLBP.ConclusionsThe results of this study confirmed a benefit of mountain hiking combined with Mg-Ca-SO4 spa therapy as a multimodal treatment of patients with nscLBP. Further studies should focus on long-term-effects of this therapeutic approach.Trial registrationISRCTN, ISRCTN99926592. Registered 06. July 2018 - Retrospectively registered.

Applicability and cross-cultural validation of the Chinese version of the Warwick-Edinburgh mental well-being scale in patients with chronic heart failure

BackgroundThe mental well-being of patients with chronic heart failure is likely to influence their health-related quality of life and decrease the utilization of public health resources. This study assessed the mental well-being of patients with chronic heart failure and evaluated the reliability and validity of the Warwick-Edinburgh Mental Well-Being Scale.MethodsWe conducted a cross-sectional survey from July 2016 to July 2017 among 191 patients with chronic heart failure, and examined psychometric properties of the Warwick-Edinburgh Mental Well-Being Scale, such as internal consistency, reliability, test-retest reliability, and factorial validity of the Chinese version of the Warwick-Edinburgh Mental Well-Being Scale.ResultsOne-dimensional construct validity was demonstrated by confirmatory factor analysis. The psychometric properties of the Chinese version of the Warwick-Edinburgh Mental Well-Being Scale were satisfactory in our sample of patients with chronic heart failure. The internal consistency reliability was .948 and the test-retest reliability .925. The item-total correlations ranged from .405 to .872. There was a strong correlation (r = .79) between the Chinese version of the Warwick-Edinburgh Mental Well-Being Scale and the five-item World Health Organization Well-Being Index. The Chinese version of the Warwick-Edinburgh Mental Well-Being Scale appears acceptable for use in patients with chronic heart failure, and we were able to verify its reliability and validity with our sample.ConclusionsThe Chinese version of the Warwick-Edinburgh Mental Well-Being Scale is a reliable quantitative tool for evaluating mental well-being in patients with chronic heart failure in clinical settings, and this has important implications for overall assessments of mental well-being in patients with chronic heart failure.

The effect of nature exposure on the mental health of patients: a systematic review

The effect of nature-based interventions on self-reported mental well-being in patients with physical disease is gaining increasing attention. However, there is a lack of randomized controlled trials investigating this area. Due to the massive costs in health care systems, there is a need for new strategies to address these issues and an urgent need for attention to this field. Nature-based interventions are low cost, easy to implement, and should get attention within the health care field. Therefore, the objective was to find the impact of nature interventions on mental well-being in humans with a physical disease. In four major databases (PubMed, Cinahl, PsycINFO, and Cochrane Library), a systematic review of quantitative studies of nature's impact on self-reported mental health in patients with physical disease was performed. A total of 1909 articles were retrieved but only five met the inclusion criteria and were summarized. All five studies were quantitative, with a control group and a nature-based intervention. A source of heterogeneity was identified: the patients in one of the five studies were psychosomatic. In the four studies with somatic patients, significant benefit of nature on self-reported mental health outcomes was found; the only study that failed to show a significant benefit was the one with psychosomatic patients. A significant effect of nature on mental well-being of patients with somatic disease was found. The result in patients with psychosomatic disease is inconclusive, and more studies in this category are needed. Further research on the effect of nature on mental health is merited, with special attention to standardizing intervention type and dose as well as outcome measures within each medical discipline.

Evaluation of body image perception in multiple sclerosis patients without neurological deficit.

There is a lack of research on the association between body image perception (BIP) and multiple sclerosis (MS). The aim of this study was to evaluate BIP in MS patients and its correlation with depression, anxiety, duration of the disease, and sociodemographic characteristics of the patients. Fifty patients with MS who applied to our outpatient clinic were examined. Forty-five healthy control were recruited for the study. All patients were diagnosed with MS according to 2010 revisions of McDonald criteria. Expanded Disability Status Scale (EDSS) was performed by the same neurologist for all patients. The participants were asked to complete a sociodemographic form, Body Cathexis Scale (BCS), Beck Depression Inventory (BDI), and Beck Anxiety Inventory (BAI). The mean BCS score was 86.54 ± 32.24 in MS patients and 155.00 ± 20.90 in the healthy subjects (p<0.001). While MS patients had significantly higher anxiety levels, depression scores were similar in both groups. The mean BAI score was 18.50 ± 14.03 for MS patients and 10.06 ± 7.96 in the control group (p=0.001). The BDI score of the patients was 13.77 ± 11.61 and 11.91 ± 8.65 for the controls (p=0.34). Early age of the disease onset, increased number of attacks, increased depressive symptoms, and higher anxiety levels were significantly correlated with higher BCS scores. Age and being single/ divorced/ widowed were also correlated with BCS scores. It is important to preserve the mental well-being of patients. Even in apparently healthy patients, the body perception may be severely impaired.

Urological cancers and mental wellbeing: are we helping our patients? A systematic review of current interventions to support patients

Urological cancers and mental wellbeing: are we helping our patients? A systematic review of current interventions to support patients

Patient reported barriers are associated with low physical and mental well-being in patients with co-morbid diabetes and chronic kidney disease

BackgroundLittle is known about how patient reported barriers to health care impact the quality of life (HRQoL) of patients with comorbid disease. We investigated patient reported barriers to health care and low physical and mental well-being among people with diabetes and chronic kidney disease (CKD).MethodsAdults with diabetes and CKD (estimated Glomerular Filtration Rate < 60 ml/min/1.73m2) were recruited and completed a questionnaire on barriers to health care, the 12-Item HRQoL Short Form Survey and clinical assessment. Low physical and mental health status were defined as mean scores < 50. Logistic regression models were used.ResultsThree hundred eight participants (mean age 66.9 ± 11 years) were studied. Patient reported ‘impact of the disease on family and friends’ (OR 2.07; 95% CI 1.14 to 3.78), ‘feeling unwell’ (OR 4.23; 95% CI 1.45 to 12.3) and ‘having other life stressors that make self-care a low priority’ (OR 2.59; 95% CI 1.20 to 5.61), were all associated with higher odds of low physical health status. Patient reported ‘feeling unwell’ (OR 2.92; 95% CI 1.07 to 8.01), ‘low mood’ (OR 2.82; 95% CI 1.64 to 4.87) and ‘unavailability of home help’ (OR 1.91; 95% CI 1.57 to 2.33) were all associated with higher odds of low mental health status. The greater the number of patient reported barriers the higher the odds of low mental health but not physical health status.ConclusionsPatient reported barriers to health care were associated with lower physical and mental well-being. Interventions addressing these barriers may improve HRQoL among people with comorbid diabetes and CKD.

The Effects of Music Therapy on Cognition, Psychiatric Symptoms, and Activities of Daily Living in Patients with Alzheimer's Disease.

Alzheimer's disease (AD) is the most common type of dementia, affecting millions of older people worldwide. However, pharmacological therapies have not achieved desirable clinical efficacy in the past decades. Non-pharmacological therapies have been receiving increased attention to treat dementia in recent years. This study explores the effects of music therapy on cognitive function and mental wellbeing of patients with AD. A total number of 298 AD patients with mild, moderate, or severe dementia participated in the study. The participants with each grade of severity were randomly divided into three groups, which were a singing group, a lyric reading group, and a control group. These three groups received different interventions for three months. All participants underwent a series of tests on cognitive functions, neuropsychological symptoms, and activities of daily living at baseline, three months, and six months. The analysis shows that music therapy is more effective for improving verbal fluency and for alleviating the psychiatric symptoms and caregiver distress than lyrics reading in patients with AD. Stratified analysis shows that music therapy is effective for enhancing memory and language ability in patients with mild AD and reducing the psychiatric symptoms and caregiver distress in patients with moderate or severe AD. However, no significant effect was found for activities of daily living in patients with mild, moderate, or severe AD. This study suggests that music therapy is effective in enhancing cognitive function and mental wellbeing and can be recommended as an alternative approach to manage AD associated symptoms.

RETRACTED ARTICLE: Esoteric Connective Tissue Therapy for chronic low back pain to reduce pain, and improve functionality and general well-being compared with physiotherapy: study protocol for a randomised controlled trial

BackgroundLow back pain causes more global disability than any other condition. Once the acute pain becomes chronic, about two-thirds of sufferers will not fully recover after 1–2 years. There is a paucity of effective treatments for non-specific, chronic low back pain.It has been noted that low back pain is associated with changes in the connective tissue in the affected area, and a very low-impact treatment, Esoteric Connective Tissue Therapy (ECTT), has been developed to restore flexibility in connective tissue. ECTT uses patterns of very small, circular movements, to the legs, arms, spine, sacrum and head, which anecdotally are effective in pain relief. In an unpublished single-arm phase I/II trial with chronic pain patients, ECTT showed a 56% reduction in pain after five treatments and 45% and 54% improvements at 6 months and 7–9 years of follow-up respectively.MethodsThe aim of this randomised controlled trial is to compare ECTT with physiotherapy for reducing pain and improving physical function and physical and mental well-being in patients with chronic low back pain.The trial will be held at two hospitals in Vietnam. One hundred participants with chronic low back pain greater than or equal to 40/100 on the visual analogue scale will be recruited and randomised to either ECTT or physiotherapy. Four weekly treatments will be provided by two experienced ECTT practitioners (Treatment Group, 40 minutes each) and hospital-employed physiotherapy nurses (Control Group, 50 minutes).The primary outcomes will be changes in pain, physical function per the Quebec Pain Functionality Questionnaire and physical and mental well-being recorded by the Short Form Health Survey (SF-36), with mixed modelling used as the primary statistical tool because the data are longitudinal. Initial follow-up will be at either 4 or 8 months, with a second follow-up after 12 months.DiscussionThe trial design has important strengths, because it is to be conducted in hospitals under medical supervision, because ECTT is to be compared with a standard therapy and because the assessor and analyst are to be blinded. The findings from this trial will provide evidence of the efficacy of ECTT for chronic low back pain compared with standard physiotherapy treatment.Trial registrationAustralian New Zealand Clinical Trials Registry, ACTRN12616001196437. Registered on 30 August 2016.

The Psychological Processes of Adaptation and Hope in Patients with Multiple Sclerosis: A Thematic Synthesis

Purpose: The purpose of the current research was to review the lived experiences of patients with multiple sclerosis (MS) in order to extrapolate the psychological process of adaptation. Methods: A thematic synthesis was undertaken within 3 phases: systematic search for literature, critical appraisal of included studies and synthesis of research. Results: A total of 47 studies were included in this review, this included 1146 (812 females, 265 males, and 69 unknown) unique patients with MS (aggregated mean age: 49.3 years [30/47 studies], aggregated time with illness: 12.3 years [28/47 studies]). The critical appraisal of research illustrated that the design of the studies and the reference to reflexivity in studies were not well considered. The synthesis was able to identify a primary response of psychological adaptation as well as distinct coping strategies. A model of emotion, hope, and adjustment was identified. Conclusion: Simple processes of adaptation for people with MS can be considered by clinicians and utilised to promote mental well-being in patients. Clinicians and researchers also need to be aware of the important psychological needs of patients during interactions. Discussion and clinical implications are provided.

The Effect of Breathing Exercise on Fatigue and Stress in Patients with Coronary Artery Diseases: A Randomized Controlled Trial

The Effect of Breathing Exercise on Fatigue and Stress in Patients with Coronary Artery Diseases: A Randomized Controlled Trial Complementary and alternative medicine methods, when used in addition to medical treatments, increase the physical and mental well-being of patients. This study was planned to examine the effects of breathing exercises, which are a complementary and alternative medicine method, on the stress and fatigue levels of patients with coronary artery disease. The study was planned as a randomized, controlled, and experimental study. A patient identification form, the Perceived Stress Scale, and the Piper Fatigue Scale were used in data collection. In the experimental group, the rate of phase 1-3 hypertension fell to 8.4% in the second monitoring from 30.0% (p<0.05).

Crying Without Tears: Dimensions of Crying and Relations With Ocular Dryness and Mental Well-Being in Patients With Sjögren's Syndrome.

This study examined dimensions of crying and its relations with ocular dryness and mental well-being in patients with Sjögren's syndrome, a systemic autoimmune disease with dryness as primary symptom. Three-hundred patients with Sjögren's syndrome completed questionnaires on crying, dryness, and well-being. The crying questionnaire revealed four dimensions: "Cryability" (comprising both crying sensibility and ability to cry), Somatic consequences, Frustration, and Suppression. Compared to 100 demographically-matched control participants from the general population, patients scored low on Cryability and high on Somatic consequences and Frustration. The crying dimensions generally showed significant but weak associations with ocular dryness and mental well-being in patients. This is the first quantitative study indicating that crying problems are more common in patients with Sjögren's syndrome than in the general population. Perhaps, patients who experience problems with crying could be helped to rely on other ways of expressing emotions than crying in tear-inducing situations.

Diagnosis and treatment of Graves' disease with particular emphasis on appropriate techniques in nuclear medicine. General state of knowledge.

Graves' disease is an autoimmune disease. It accounts for 50-80% of cases of hyperthyroidism. Antibodies against the TSH receptor (TRAb) are responsible for hyperthyroidism (TRAB). The key role in monitoring and diagnosis of Graves' disease plays the level of hormones of free thyroxine and triiodothyronine. Helpful is an ultrasound of the thyroid scintigraphy which due to its functional character is both a valuable addition to morphological studies as well as plays an important role in the diagnosis and therapy in patients with Graves' disease. There is no perfect treatment for Graves' disease. The reason for this is the lack of therapy directed against primary pathogenic mechanisms. Currently available treatments need to be thoroughly discussed during the first visit as the patient's understanding of the choice of a treatment constitutes a vital role in the success of therapy. Graves' disease treatment is based on three types of therapies that have been carried out for decades including: pharmacological treatment anti-thyroid drugs, I131 therapy and radical treatment - thyroidectomy. The purpose of the treatment is to control symptoms and patient to return to euthyreosis. Treatment of Graves' disease is of great importance because if left untreated, it can lead to long-term harmful effects on the heart, bone and mental well-being of patients.

Effects of Group-based versus Individual-based Spinal Stability Exercises (SSE) on Physical Health and Mental Wellbeing of Patients with Chronic Low Back Pain (LBP): A Randomized Controlled Trial (RCT)

Background: Several studies have demonstrated the efficacy of spinal stability exercises in physiotherapy management of back pain disorders. Physiotherapists traditionally can administer this exercise treatment either with the patient in group or one to one basis. There is dearth of information on the relative efficacy of group-based and individual-based spinal stabilisation exercise treatment approach. This raises the question of which method is more effective in symptom remediation and improvement in the health status of patients with chronic LBP? Purpose: The purpose of this study was to compare the effect of group-based and individual-based SSE on bodily pain, functional limitation, physical health and mental wellbeing of patients with chronic LBP. Method: Thirty-five participants with chronic LBP were randomly assigned to undergo a SSE twice weekly week for 8 consecutive weeks in a group setting, and 35 participants received the same SSE on an individual basis during the same period. Functional limitation was assessed with Rolland Morris Disability Questionnaires. Bodily pain, physical health and mental well-being were evaluated with Rand 36 questionnaire. Assessments were carried out preintervention, post-intervention and at 3-month follow up. Results: Significant improvement in bodily pain, functional limitation, physical health and mental well-being were found in both the group-based SSE and individual-based SSE post intervention (P=0.00). Functional limitation did not show significant difference between the two groups post intervention (P=0.497). Friedman ANOVA showed significant within-group differences over time in bodily pain, functional limitation. Physical health and mental well-being over time (P=0.00) that favoured the group-based SSE. Conclusion: Findings from this study showed that group-based spinal stabilisation exercise interventions, is more effective in reducing pain, improving physical health and mental well-being of patients with chronic LBP than individually-based programs.

Impact of medication, nutrition and routine exercise on mental health of patients

Mental Health of a patient is one of the most prior concerns for all over well-being of an individual. Mental health is a level of psychological well-being or absence of a mental disorders. It is a psychological state of someone who is functioning at a satisfactory level of emotional and behavioral adjustment. The effect of good nutrition, routine exercise and medication were examined on mental well-being of patients in comparison to patients who were only using medication. The sample comprised of 20 patients suffering from hypertension. The sample was further divided into two groups. For about (10) patients practiced exercise twice a day for about 25–30 minutes with healthy nutritious diet and medication, whereas the other (10) patients depend only on medication. Mental well-being scale was used for recording the mental assessment of the subject. Self-devised questionnaire was the main tool for collecting the primary data. The research analysis was carried out by percentage evaluation method and t-test was used to see the significant difference between the two groups. The result shows that routine exercise and proper nutrition leads to significant improvement in the mental state of patients as compared to the patients using only medicine. The result showed that routine exercise with good nutrition has a very significant effect on mental health of the patients with loss of anxiety aggression and depression with increased vitality and life balance.

PARE0021 Challenging Mental Health Disorder in Long Term Rheumatic Disease Clinics

BackgroundThe prevalence of mental health disorder in individuals with Rheumatic disease is higher than that of the general population1,2. An audit of 240 patients attending general and specialist Rheumatology clinics...