Proactive Interference Research Articles

Dual-Task Interference in the Assessment of Listening Effort: Results of Normal-Hearing Adults, Cochlear Implant Users, and Hearing Aid Users.

The purpose of the current study was to assess dual-task interference (i.e., changes between the dual-task and baseline condition) in a listening effort dual-task paradigm in normal-hearing (NH) adults, hearing aid (HA) users, and cochlear implant (CI) users. Three groups of 31 participants were included: (a) NH adults, (b) HA users, and (c) CI users. The dual-task paradigm consisted of a primary speech understanding task in a quiet condition, and a favorable and unfavorable noise condition, and a secondary visual memory task. Dual-task interference was calculated for both tasks, and participants were classified based on their patterns of interference. Descriptive analyses were established and differences between the three groups were examined. The descriptive results showed varying patterns of dual-task interference between the three listening conditions. Most participants showed the pattern of visual memory interference (i.e., worse results for the secondary task in the dual-task condition and no difference for the primary task) in the quiet condition, whereas the pattern of speech understanding priority trade-off (i.e., worse results for the secondary task in the dual-task condition and better results for the primary task) was most prominent in the unfavorable noise condition. Particularly, in HA and CI users, this shift was seen. However, the patterns of dual-task interference were not statistically different between the three groups. Results of this study may provide additional insight into the interpretation of dual-task paradigms for measuring listening effort in diverse participant groups. It highlights the importance of considering both the primary and secondary tasks for accurate interpretation of results. https://doi.org/10.23641/asha.26409088.

The proactive and reactive mechanisms of learned spatial suppression.

Selection history refers to the notion that previous allocations of attention or suppression have the potential to elicit lingering and enduring selection biases that are isolated from goal-driven or stimulus-driven attention. However, in the singleton detection mode task, manipulating the selection history of distractors cannot give rise to pure proactive inhibition. Therefore, we employed a combination of a working memory task and a feature search mode task, simultaneously recording cortical activity using EEG, to investigate the mechanisms of suppression guided by selection history. The results from event-related potential and reaction times showed an enhanced inhibitory performance when the distractor was presented at the high-probability location, along with instances where the target appeared at the high-probability location of distractors. These findings demonstrate that a generalized proactive inhibition bias is learned and processed independent of cognitive resources, which is supported by selection history. In contrast, reactive rejection toward the low-probability location was evident through the Pd component under varying cognitive resource conditions. Taken together, our findings indicated that participants learned proactive inhibition when the distractor was at the high-probability location, whereas reactive rejection was involved at low-probability location.

The economic butterfly effect of agriculture supply chains: A comparative assessment of the United States of America and Nigeria

This study will seek to explore the disruptions and enhancements that can occur in the agricultural supply chains of the United States of America and Nigeria, which can cause the butterfly effect and subsequently affect economic results in both countries. Using case studies, economic modeling, and a qualitative analysis of government documents and academic sources, this comparative study explores the link between agriculture and other industries in the US and Nigeria. According to the paper, there is need for proactive administrative interferences and advocacy for technological advancement in efforts to enhance supply chain robustness against future shocks such as climate change, trade policies or pandemics. Responding to the negative economic externalities and maximizing the potential benefits entails comprehending how minor events in agriculture can cause ripple effects throughout the economy.

Rats show up to 72h of significant retention for spatial memory in the radial maze.

This study explored long-term retention of spatial memory in rats using an eight-arm radial maze. Crystal and Babb (Learning and motivation, 39(4), 278-284, 2008) previously demonstrated that rats could retain spatial memory for up to 25h in the radial maze. Notably, they found performance improved with 48-h intertrial intervals compared with 24-h intervals. Our study investigated the effects of extending intertrial intervals on long-term retention of spatial memory by reducing the potential for proactive interference. Each trial comprised a learning phase, during which subjects were required to sequentially visit four randomly selected arms, followed by a free-choice test that included all eight arms, conducted after increasing the retention and intertrial intervals. The retention intervals were systematically increased from 1h to 24, 48, and, ultimately, 72h, with corresponding intertrial intervals expanding from 24 to 48, 120, and 144h. Performance significantly surpassed chance levels across all conditions, demonstrating that rats are capable of retaining spatial memory for up to 72h.

Pilot Study of Acute Behavioral Effects of Pallidal Burst Stimulation in Parkinson's Disease.

Burst-patterned pallidal deep brain stimulation (DBS) in an animal model of Parkinson's disease (PD) yields significantly prolonged therapeutic benefit compared to conventional continuous DBS, but its value in patients remains unclear. The aims were to evaluate the safety and tolerability of acute (<2 hours) burst DBS in PD patients and to evaluate preliminary clinical effectiveness relative to conventional DBS. Six PD patients were studied with DBS OFF, conventional DBS, and burst DBS. Unified Parkinson's Disease Rating Scale III (UPDRS-III) and proactive inhibition (using stop-signal task) were evaluated for each condition. Burst and conventional DBS were equally tolerated without significant adverse events. Both stimulation patterns provided equivalent significant UPDRS-III reduction and increased proactive inhibition relative to DBS OFF. This pilot study supports the safety and tolerability of burst DBS, with acute effects similar to conventional DBS. Further larger-scale studies are warranted given the potential benefits of burst DBS due to decreased total energy delivery. © 2024 The Author(s). Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.

The impact of transcranial direct current stimulation combined with interim testing on spatial route learning in patients with schizophrenia

BackgroundCognitive deficits in patients with schizophrenia have drawn widespread attention. Transcranial direct current stimulation (tDCS) can modulate cognitive processes by altering neuronal excitability. Previous studies have found that interim testing can enhance spatial route learning and memory in patients with schizophrenia. However, there has been limited research on the combined effects of these two methods on spatial route learning in these patients. ObjectiveTo investigate whether the combination of tDCS and interim testing can effectively contribute to the maintenance of spatial route memory in patients with schizophrenia. The study involved conducting route learning using interim testing after anodal tDCS treatment on the left dorsolateral prefrontal cortex (L-DLPFC). MethodsNinety-two patients with schizophrenia were recruited and divided into groups receiving anodal, sham, or no stimulation. The anodal group received L-DLPFC tDCS treatment 10 times over 5 days (twice daily for 20 min). After treatment, spatial route learning was assessed in interim testing. Correct recall rates of landmark positions and proactive interference from prior learning were compared among the groups. ResultsRegardless of stimulation type, the interim testing group outperformed the relearning group. Additionally, recall scores were higher following anodal stimulation, indicating the efficacy of tDCS. ConclusionsBoth tDCS and interim testing independently enhance the ability to learn new information in spatial route learning for patients with schizophrenia, indicating that tDCS of the left DLPFC significantly improves memory in these patients.

Inhibitory control of gait initiation in humans: An electroencephalography study.

Response inhibition is a crucial component of executive control. Although mainly studied in upper limb tasks, it is fully implicated in gait initiation. Here, we assessed the influence of proactive and reactive inhibitory control during gait initiation in healthy adult participants. For this purpose, we measured kinematics and electroencephalography (EEG) activity (event-related potential [ERP] and time-frequency data) during a modified Go/NoGo gait initiation task in 23 healthy adults. The task comprised Go-certain, Go-uncertain, and NoGo conditions. Each trial included preparatory and imperative stimuli. Our results showed that go-uncertainty resulted in delayed reaction time, without any difference for the other parameters of gait initiation. Proactive inhibition, that is, Go uncertain versus Go certain conditions, influenced EEG activity as soon as the preparatory stimulus. Moreover, both proactive and reactive inhibition influenced the amplitude of the ERPs (central P1, occipito-parietal N1, and N2/P3) and theta and alpha/low beta band activities in response to the imperative-Go-uncertain versus Go-certain and NoGo versus Go-uncertain-stimuli. These findings demonstrate that the uncertainty context; induced proactive inhibition, as reflected in delayed gait initiation. Proactive and reactive inhibition elicited extended and overlapping modulations of ERP and time-frequency activities. This study shows the protracted influence of inhibitory control in gait initiation.

Enhancement of piezoelectric energy harvesting for flexural waves by a metasurface-assisted phononic cavity

Piezoelectric energy harvesting of mechanical waves exhibits great potential applications in electricity generation for low-powered electronic devices. In this work, the metasurface-assisted phononic cavity is proposed for the enhancement of piezoelectric energy harvesting of elastic flexural waves. By employing the two-dimensional plate-type metamaterial, we construct a phononic cavity that possesses the ability to localize and amplify the flexural waves. On the other hand, for the purpose of flexural wave focusing, a sparse metasurface is inversely designed based on the interference theory through the particle swarm optimization algorithm. For collaborative wave manipulation, the sparse metasurface is set in front of the phononic cavity. Additionally, piezoelectric patches are attached within the phononic cavities. The wave characteristics of the metasurface-assisted phononic cavity are studied by using the finite element method. For comparison, a conventional phononic cavity (i.e., cavity without metasurface) and a reference bare plate are also considered. Due to the wavefront control ability of the metasurface, more flexural waves are guided into the phononic cavity region. Thus, compared with the reference plate, the power amplification ratios of the metasurface-assisted cavity and the conventional cavity are 102 and 7, respectively. The electrical outputs of the phononic cavity are remarkably boosted by the assistance of the sparse metasurface.

Modelling and analysis of a triple-band metamaterial absorber for early-stage cervical cancer HeLa cell detection

The paper introduces a unique design and analysis of a terahertz metamaterial absorber (MMA) that can be used for early detection of cervical cancer by employing microwave imaging techniques. Computer Simulation Technology (CST) is used to design and analyze the proposed absorber. The MMA operates in the frequency range of 6–8 THz and can absorb energy in three specific spectral bands: 6.606 THz, 6.824 THz, and 7.426 THz, with absorption peaks of 99.75 %, 99.87 %, and 99.73 % correspondingly. The working principle of the absorber is described using the impedance matching and interference theory. The electric field (E), magnetic field (H), and surface current of the MMA are also examined. Finally, detecting cancerous HeLa cells is also being investigated by analyzing the E-field and H-field using microwave imaging. The suggested biosensor features a high-quality factor of 494.3, a frequency shifts per refractive index of 1.08 THz/RIU, and a figure of merit (FOM) of 42. The suggested MMA-based sensor has numerous advantages and can be utilized for early-stage cervical cancer detection.

Bimodal Absorber Frequencies Shift Induced by the Coupling of Bright and Dark Modes.

In this paper, we demonstrate that the absorption frequencies of the bimodal absorber shift with the coupling strength of the bright and dark modes. The coupling between the bright mode and the dark mode can acquire electromagnetically induced transparency, we obtain the analytical relationship between the absorbing frequencies, the resonant frequencies, losses of the bright mode and dark mode, and the coupling strength between two modes by combining the coupled mode theory with the interference theory. As the coupling strength between the bright mode and the dark mode decreases, the two absorption peaks gradually move closer to each other, inversely, they will move away from each other. The simulation employs three distinct metasurface structures with coupling of the bright and dark modes, thereby verifying the generality of the theoretical findings.

The auditory stimulus facilitates memory guidance in distractor suppression in males with substance use disorder.

Representations in working memory can affect distractor suppression in human visual search, and this process is modulated by a separate top-down cognitive control. An increasing body of research has demonstrated that patients with substance use disorder (SUD) have deficits in cognitive control over filtering interference by perceptual distractors. However, their ability to resist proactive interference from working memory has received comparatively less attention. Here, we investigate this issue by employing a working memory/visual search dual-task paradigm. An intervening gap-location search task was instructed to be performed while participants memorized a written color word, with congruent auditory information present during the memory encoding phase on half of the trials. Results showed that there was a reliable response time (RT) advantage when the meaning of the memory sample agreed with the color of one of the distractors under the visual alone condition. However, such a result was only found in the control group. More importantly, both groups exhibited comparable facilitation under the audiovisual condition, with the facilitation effect appearing later in the SUD group. Furthermore, the facilitation effect was superior in magnitude and time course under the audiovisual condition to the visual alone condition. These findings highlight how patients with SUD resist distractor interference at the memory level and extend our understanding of how working memory, selective attention, and audiovisual enhancement interact to optimize perceptual decisions in patients with SUD.

Vulnerability to semantic and phonological interference in normal aging and amnestic mild cognitive impairment (aMCI).

To determine whether the increased vulnerability to semantic interference previously observed in amnestic mild cognitive impairment (aMCI) is specifically associated with semantic material or if it also affects other types of material, suggesting generalized executive and inhibitory impairment. Seventy-two participants divided into two groups (33 aMCI, 39 normal control [NC]) matched for age and education were included. They completed a comprehensive neuropsychological examination, the French version of the Loewenstein Acevedo Scale for Semantic Interference and Learning (LASSI-L; semantic interference test), and a homologous experimental phonological test, the phonological interference and learning test. Independent sample t tests, mixed analysis of variance (ANOVA), and analysis of covariance (ANCOVA) on memory and interference scores were conducted to compare memory and interference in both conditions for both groups. For memory scores, results revealed significant main effects of group (NC > aMCI) and condition (semantic > phonological) and significant interactions (poorer performance in the semantic condition for aMCI). aMCI committed more phonological false recognition errors, were disproportionately more vulnerable to retroactive semantic interference, and showed a higher percentage of intrusion errors associated with proactive semantic interference than NC. To our knowledge, this is the first study to compare vulnerability to interference in aMCI and normal aging with two similarly designed semantic and phonological word list learning tasks. Taken together, our results suggest that aMCI present with broad difficulties in source memory and inhibition, but that impaired deep semantic processing results in additional semantic intrusion errors during proactive interference and impacts their ability to show good recall after an interference list (greater semantic retroactive interference). Results are discussed according to the level-of-processing and activation/monitoring theories. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

Effect of Mixed Morphology (Simple Cubic, Face-Centered Cubic, and Body-Centered Cubic)-Based Electrodes on the Electric Double Layer Capacitance of Supercapacitors.

Supercapacitors store energy due to the formation of an electric double layer (EDL) at the interface of the electrodes and electrolyte. The present article deals with the finite element study of equilibrium electric double layer capacitance (EDLC) in the mixed morphology electrodes comprising all three fundamental crystal structures, simple cubic (SC), body-centered cubic (BCC), and face-centered cubic morphologies (FCC). Mesoporous-activated carbon forms the electrode in the supercapacitor with (C2H5)4NBF4/propylene carbonate organic electrolyte. Electrochemical interference is clearly demonstrated in the supercapacitors with the formation of the potential bands, as in the case of interference theory due to the increasing packing factor. The effects of electrode thickness varying from a wide range of 50 nm to 0.04 mm on specific EDLC have been discussed in detail. The interfacial geometry of the unit cell in contact with the electrolyte is the most important parameter determining the properties of the EDL. The critical thickness of the electrodes is 1.71 μm in all the morphologies. Polarization increases the interfacial potential and leads to EDL formation. The Stern layer specific capacitance is 167.6 μF cm-2 in all the morphologies. The maximum capacitance is in the decreasing order of interfacial geometry, as FCC > BCC > SC, dependent on the packing factor. The minimum transmittance in all the morphologies is 98.35%, with the constant figure of merit at higher electrode thickness having applications in the chip interconnects. The transient analysis shows that the interfacial current decreases with increasing polarization in the EDL. The capacitance also decreases with the increase of the scan rate.

Detection of cerebrospinal fluid biomarkers changes of Alzheimer's disease using a cognitive stress test in persons with subjective cognitive decline and mild cognitive impairment.

Timely and accurate diagnosis of the earliest manifestations of Alzheimer's disease (AD) is critically important. Cognitive challenge tests such as the Loewenstein Acevedo Scales for Semantic Interference and Learning (LASSI-L) have shown favorable diagnostic properties in a number of previous investigations using amyloid or FDG PET. However, no studies have examined LASSI-L performance against cerebrospinal fluid biomarkers of AD, which can be affected before the distribution of fibrillar amyloid and other changes that can be observed in brain neuroimaging. Therefore, we aimed to evaluate the relationship between LASSI-L scores and CSF biomarkers and the capacity of the cognitive challenge test to detect the presence of amyloid and tau deposition in patients with subjective cognitive decline and amnestic mild cognitive impairment (MCI). One hundred and seventy-nine patients consulting for memory loss without functional impairment were enrolled. Patients were examined using comprehensive neuropsychological assessment, the LASSI-L, and cerebrospinal fluid (CSF) biomarkers (Aβ1-42/Aβ1-40 and ptau181). Means comparisons, correlations, effect sizes, and ROC curves were calculated. LASSI-L scores were significantly associated with CSF biomarkers Aβ1-42/Aβ1-40 in patients diagnosed with MCI and subjective cognitive decline, especially those scores evaluating the capacity to recover from proactive semantic interference effects and delayed recall. A logistic regression model for the entire sample including LASSI-L and age showed an accuracy of 0.749 and an area under the curve of 0.785 to detect abnormal amyloid deposition. Our study supports the biological validity of the LASSI-L and its semantic interference paradigm in the context of the early stages of AD. These findings emphasize the utility and the convenience of including sensitive cognitive challenge tests in the assessment of patients with suspicion of early stages of AD.

The resolution of proactive interference in a novel visual working memory task: A behavioral and pupillometric study.

Proactive interference (PI) occurs when previously learned information impairs memory for more recently learned information. Most PI studies have employed verbal stimuli, while the role of PI in visual working memory (VWM) has had relatively little attention. In the verbal domain, Johansson and colleagues (2018) found that pupil diameter - a real-time neurophysiological index of cognitive effort - reflects the accumulation and resolution of PI. Here we use a novel, naturalistic paradigm to test the behavioral and pupillary correlates of PI resolution for what-was-where item-location bindings in VWM. Importantly, in our paradigm, trials (PI vs. no-PI condition) are mixed in a block, and participants are naïve to the condition until they are tested. This design sidesteps concerns about differences in encoding strategies or generalized effort differences between conditions. Across three experiments (N = 122 total) we assessed PI's effect on VWM and whether PI resolution during memory retrieval is associated with greater cognitive effort (as indexed by the phasic, task-evoked pupil response). We found strong support for PI's detrimental effect on VWM (even with our spatially distributed stimuli), but no consistent link between interference resolution and effort during memory retrieval (this, even though the pupil was a reliable indicator that higher-performing individuals tried harder during memory encoding). We speculate that when explicit strategies are minimized, and PI resolution relies primarily on implicit processing, the effect may not be sufficient to trigger a robust pupillometric response.

Age differences in the principal temporo-spatial components of EEG activity during a proactive interference task

Proactive interference (PI) is the disruptive effect of no longer relevant information on current working memory (WM) processing. PI effects in EEG data have been previously found to be altered in healthy aging, although it remains unclear the extent to which such changes reflect delayed or different brain mechanisms employed to overcome PI. Hence, we had twenty-six young (18–34 years) and sixteen old (53–68 years) healthy adults complete a Recent Probes task while EEG was recorded. Compared to young adults, old adults were slower, less accurate and less able to discriminate when they last saw a given stimulus, but PI effects on reaction time were greater in the former, likely due to a general difficulty that old adults had in the task. Temporo-spatial principal component analysis of the EEG data showed young and older adults to differ in terms of temporal and spatial characteristics of brain activity associated with resolving PI. YA showed a factor indicative of a medial frontal negativity (MFN) that showed greater amplitude in low compared to high PI trials. OA, in contrast, showed a late positive component (LPC), although similarly with larger amplitude in low compared to high PI trials. The modulation of the MFN component in YA may reflect the recruitment of cognitive control to overcome PI. The modulation of the LPC in OA may represent the detection of conflict between familiarity and context recollection during PI.

A dual mechanisms of control account of age differences in working memory.

Age-related differences in working memory (WM) can be large, but the exact sources are unclear. We hypothesized that young adults outperform older adults on WM tasks because they use controlled attention processes to prioritize the maintenance of relevant information in WM in a proactive mode, whereas older adults tend to rely on the strength of familiarity signals to make memory decisions in a reactive mode. We used a WM task that cued participants to prioritize one item over others and presented repeated lure probes that cause errors when one is engaged in a reactive mode. Results showed that, relative to young adults with full attention available to use proactive control during the delays, older adults with full attention (and young adults with divided attention) during the delays had exaggerated error rates to repeated lure probes compared to control probes. When the amount of proactive interference was increased (by repeating stimuli across trials), older adults were able to engage in proactive control, and this eliminated their exaggerated error rate (while young adults with divided attention could not). These results provide evidence for a dual mechanisms of control account of age differences in WM. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

Interference underlies attenuation upon relearning in sensorimotor adaptation.

Savings refers to the gain in performance upon relearning a task. In sensorimotor adaptation, savings is tested by having participants adapt to perturbed feedback and, following a washout block during which the system resets to baseline, presenting the same perturbation again. While savings has been observed with these tasks, we have shown that the contribution from implicit sensorimotor adaptation, a process that uses sensory prediction errors to recalibrate the sensorimotor map, is actually attenuated upon relearning (Avraham et al., 2021). In the present study, we test the hypothesis that this attenuation is due to interference arising from the washout block, and more generally, from experience with a different relationship between the movement and the feedback. In standard adaptation studies, removing the perturbation at the start of the washout block results in a salient error signal in the opposite direction to that observed during learning. As a starting point, we replicated the finding that implicit adaptation is attenuated following a washout period in which the feedback now signals a salient opposite error. When we eliminated visual feedback during washout, implicit adaptation was no longer attenuated upon relearning, consistent with the interference hypothesis. Next, we eliminated the salient error during washout by gradually decreasing the perturbation, creating a scenario in which the perceived errors fell within the range associated with motor noise. Nonetheless, attenuation was still prominent. Inspired by this observation, we tested participants with an extended experience with veridical feedback during an initial baseline phase and found that this was sufficient to cause robust attenuation of implicit adaptation during the first exposure to the perturbation. This effect was context-specific: It did not generalize to movements that were not associated with the interfering feedback. Taken together, these results show that the implicit sensorimotor adaptation system is highly sensitive to memory interference from a recent experience with a discrepant action-outcome contingency.

The role of culture and semantic organization in working memory updating

ABSTRACT Westerners tend to relate items in a categorical manner, whereas Easterners focus more on functional relationships. The present study extended research on semantic organization in long-term memory to working memory. First, Americans’ and Turks’ preferences for categorical versus functional relationships were tested. Second, working memory interference was assessed using a 2-back working memory paradigm in which lure items were categorically and functionally related to targets. Next, a mediation model tested direct effects of culture and semantic organization on working memory task behaviour, and the indirect effect, whether semantic organization mediated the relationship between culture and working memory interference. Whereas Americans had slower response times to correctly rejecting functional lures compared to categorical lures, conditions did not differ for Turks. However, semantic organization did not mediate cultural difference in working memory interference. Across cultures, there was evidence that semantic organization affected working memory errors, with individuals who endorsed categorical more than functional pairings committing more categorical than functional errors on the 2-back task. Results align with prior research suggesting individual differences in use of different types of semantic relationships, and further that literature by indicating effects on interference in working memory. However, these individual differences may not be culture-dependent.

Proactive interference of visual working memory chunks implicates long-term memory.

Visual working memory (VWM) is a limited cognitive resource that can be functionally expanded through chunking (Miller, 1956). For example, participants can hold an increasing number of colours in mind as they learn to chunk reliably paired combinations (Bradyet al.,2009). We investigated whether this benefit is mediated through the in situ compression of VWM representations (Brady et al.,2009) or the offloading of chunks to long-term memory (LTM; Huang & Awh, 2018; Ngiam et al., 2019) by asking if a vulnerability of LTM - proactive interference - influences VWM performance. We adapted previous designs using deterministic (Experiment 1, N = 60) and probabilistic pairings (Experiments 2 and 3, N = 64 and 80, respectively), to include colour pairings that swapped in sequence along with pairings that were consistent in sequence. Generally, participants reported colours from consistent pairs more accurately than from swapping pairs, which we designed to drive interference in LTM (Experiments 1 and 2). The error profiles also pointed to proactive interference between swapping pairs in all three experiments. Moreover, participants who had explicit awareness of frequent colour pairings had higher VWM accuracy, and their errors reflected more proactive interference than their unaware counterparts (Experiment 3). This pattern of long-term proactive interference in a VWM task lends support for accounts of VWM chunking that propose LTM offloading.