A new coronavirus infection (COVID-19) caused by acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has changed the lives of many people around the world. During the pandemic, hundreds of thousands of genomic sequences of the new coronavirus were formed, and its steady transmission from person to person remains. The use of disposable personal protective equipment (PPE) has become necessary to combat the COVID-19 pandemic, which has led to an unprecedented increase in the number of their production. Is of great concern the accumulation of the number of used PPE (medical and household waste), as well as their further disposal. The presence of various fragments of plastic and chemicals in disposable PPE can cause ecotoxicological effects on representatives of aquatic and terrestrial habitats at different levels of biological organization. In addition, PPE is a great danger for the further spread of various viruses, including SARS-CoV-2, since viruses can remain on different surfaces for several days. In the current situation, it is obvious that there is a need to conduct research to assess environmental risks and the impact of used PPE on the environment and human health