Case Reports1 March 1961HEMOCHROMATOSIS AND HEART FAILURE: PRESENTATION OF A CASE WITH SURVIVAL AFTER THREE YEARS' TREATMENT BY REPEATED VENESECTIONSAUL J. GROSBERG, M.D.SAUL J. GROSBERG, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-54-3-550 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptINTRODUCTIONSince Trousseau1 first described hemochromatosis, much has been written about the disease, as to both its pathology and its possible causation. In the classic monograph by Sheldon,2 myocardial failure is mentioned as an infrequent cause of death in hemochromatosis.With the advent of the use of insulin, diabetes has ceased to be the prime cause of death in hemochromatosis, and has been replaced by hepatic and cardiac failure.The reports which have appeared in recent years dealing with the heart in hemochromatosis have all stressed the fact that, once failure has manifested itself, deterioration is rapid, with survival usually...Bibliography1. Duncan GG: Diseases of metabolism. W. B. Saunders Co., Philadelphia, 1959. Google Scholar2. Sheldon JH: Hemochromatosis. Oxford University Press, London, 1935. Google Scholar3. Schreiber A: Hemochromatosis and the heart. Ann. Intern. Med. 47: 1015, 1957. LinkGoogle Scholar4. Lewis HP: Cardiac involvement in hemochromatosis. Amer. J. Med. Sci. 227: 544, 1954. CrossrefMedlineGoogle Scholar5. TuckerMossWilliams HSLFJP: Hemochromatosis with death from heart failure. Amer. 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DavisArrowsmith WDWR: Effect of repeated phlebotomies in hemochromatosis. J. Lab. Clin. Med. 39: 526, 1952. MedlineGoogle Scholar20. Crosby WH: Treatment of hemochromatosis by energetic phlebotomy. Brit. J. Haematol. 4: 82, 1958. CrossrefMedlineGoogle Scholar21. NorcrossO'Hollaren JWJD: Hematology clinics. I. Hemochromatosis. Lahey Clin. Bull. 10: 221, 1958. MedlineGoogle Scholar22. MyersonCarroll RMIN: Treatment of hemochromatosis by massive venesection. Arch. Intern. Med. 93: 349, 1955. CrossrefGoogle Scholar23. WarthinPetersonBarr TAEWJH: The treatment of idiopathic hemochromatosis by repeated phlebotomy. Ann. Intern. Med. 38: 1066, 1953. LinkGoogle Scholar24. Nay CP: Exogenous hemochromatosis: a case of typical hemochromatosis caused by repeated transfusions of blood. New York J. Med. 57: 3003, 1957. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Oakland, California*Received for publication December 14, 1959.From the Veterans Administration Hospital, Oakland, California.Requests for reprints should be addressed to Saul J. Grosberg, M.D., Veterans Administration Hospital, Brooklyn 9, N. Y. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byPhlebotomies as a treatment of serious heart failure due to haemochromatosis: a case reportCardiac Abnormalities in Primary HemochromatosisThe Restrictive CardiomyopathiesPrimary hemochromatosis: Anatomic and physiologic characteristics of the cardiac ventricles and their response to phlebotomyCardiac hemochromatosis: Beneficial effects of iron removal therapyIron OverloadIron Overload Disorders: Natural History, Pathogenesis, Diagnosis, and TherapyMyocardial involvement in idiopathic hemochromatosisHemochromatosis heart disease: An unemphasized cause of potentially reversible restrictive cardiomyopathyReversible Cardiomyopathy Associated with HemochromatosisThe Treatment of Hemochromatosis by PhlebotomyIdiopathic hemochromatosisIdiopathic haemochromatosis in childrenA Genetical View of Cardiovascular DiseaseMedical genetics 1961 1 March 1961Volume 54, Issue 3Page: 550-559KeywordsElectrocardiographyHeart failureHeart rateHemochromatosisHemoglobinInsulinLiverPathogenesisPhlebotomyThorax ePublished: 1 December 2008 Issue Published: 1 March 1961 PDF downloadLoading ...