Mean Quality Of Life Score Research Articles

MP67-13 RELATIONSHIP BETWEEN FRAILTY AND MENTAL HEALTH AND QUALITY OF LIFE IN LONG-TERM PROSTATE CANCER SURVIVORS AFTER RADICAL PROSTATECTOMY

You have accessJournal of UrologyCME1 Apr 2023MP67-13 RELATIONSHIP BETWEEN FRAILTY AND MENTAL HEALTH AND QUALITY OF LIFE IN LONG-TERM PROSTATE CANCER SURVIVORS AFTER RADICAL PROSTATECTOMY Kathleen Herkommer, Valentin Meissner, Lukas Lunger, Kolja Imhof, Matthias Jahnen, Donna Ankerst, Andreas Dinkel, Stefan Schiele, and Juergen Gschwend Kathleen HerkommerKathleen Herkommer More articles by this author , Valentin MeissnerValentin Meissner More articles by this author , Lukas LungerLukas Lunger More articles by this author , Kolja ImhofKolja Imhof More articles by this author , Matthias JahnenMatthias Jahnen More articles by this author , Donna AnkerstDonna Ankerst More articles by this author , Andreas DinkelAndreas Dinkel More articles by this author , Stefan SchieleStefan Schiele More articles by this author , and Juergen GschwendJuergen Gschwend More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000003330.13AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Aging-related deficits that eventually manifest as frailty are emerging as an important determinant for mental health and quality of life in older patients with cancer. The objective of the current study was (I) to assess the prevalence of frailty and (II) to elucidate the relationship between frailty and mental health as well as quality of life in long-term prostate cancer survivors after radical prostatectomy. METHODS: 2979 prostate cancer survivors from the multicenter German Familial Prostate Cancer Database were included. Patients completed standardized patient-reported outcome measures on the outcomes of interest frailty (Groningen Frailty indicator), quality of life (EORTC QLQ-C30), and anxiety/depressive symptoms (PHQ-4). Additionally, sociodemographic and clinicopathological factors as well as cancer-related self-perception were assessed. Chi square tests were used to detect differences of selected variables in frail and non-frail patients. RESULTS: The patients’ mean age was 79 years (SD=6.4) and mean time since radical prostatectomy was 18 years (SD=3.7). 33% (985/2979) of the patients were classified as frail. Regarding mental health and quality of life, frail patients reported more often depressive (24% vs. 4.0%; p<0.01) and anxiety (21% vs. 2.0%; p<0.01) symptoms and lower quality of life (mean quality of life score of 50 out of 100 vs. 70 out of 100; p<0.01) compared to non-frail patients. Frail patients were older (81 vs. 79 years; p<0.01), less often partnered (80% vs. 90%; p<0.01), and less often satisfied with their economic situation 96% vs. 99%; p<0.01) compared to non-frail patients. Frail patients had more often a secondary cancer (16% vs 12%; p<0.01), biochemical recurrence since radical prostatectomy (41% vs. 34%; p<0.01), and were more often under current prostate cancer therapy (15% vs. 8.0%; p<0.01). Cancer-related self-perception showed significant differences between frail and non-frail patients (p<0.01). For instance, frail patients perceived themselves more often as “victim” (3.0% vs. 1.4%), whereas non-frail patients favored the term “cancer conqueror” (10% vs. 7.4%). CONCLUSIONS: Prevalence of frailty is high in elderly long-term prostate cancer survivors. The association with poorer mental health and lower quality of life indicates the need for an integrated care approach including further geriatric assessment and possible interventions to improve health outcomes of these patients. Source of Funding: None © 2023 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 209Issue Supplement 4April 2023Page: e948 Advertisement Copyright & Permissions© 2023 by American Urological Association Education and Research, Inc.MetricsAuthor Information Kathleen Herkommer More articles by this author Valentin Meissner More articles by this author Lukas Lunger More articles by this author Kolja Imhof More articles by this author Matthias Jahnen More articles by this author Donna Ankerst More articles by this author Andreas Dinkel More articles by this author Stefan Schiele More articles by this author Juergen Gschwend More articles by this author Expand All Advertisement PDF downloadLoading ...

Anterior mediastinal tumor surgery applying single-port thoracoscopy using the subxiphoid approach.

This study aims to investigate the effectiveness of application of single-port thoracoscopy using the subxiphoid approach in anterior mediastinal tumor surgery. Between June 2014 and June 2016, a total of 108 patients (59 males, 49 females; mean age: 64.9±7.5 years; range, 45 to 79 years) with anterior mediastinal tumors were randomized into subxiphoid (experimental) or right chest (control) groups. Single-port thoracoscopy using the subxiphoid approach was performed in the subxiphoid group, while thoracoscopy using the right thoracic approach was performed in the control group. Preand postoperative pain stress indicators, Visual Analog Scale scores, quality of life scores, postoperative tumor recurrence, and five-year survival rates were compared between the groups. There were no mortality or serious complications in either group. The mean Visual Analog Scale pain scores on postoperative Days 1 and 7 were 6.5±0.8 and 2.9±0.8 in the subxiphoid group, respectively, compared to 7.2±0.8 and 3.4±0.8 in the control group (p<0.05 for all), respectively. The mean quality of life scores on postoperative Days 1 and 7 were 81.5±5.0 and 79.3±7.7, respectively, in the subxiphoid group compared to 72.4±4.3 and 71.3±4.8 in the control group, respectively (p<0.05 for all). Postoperative pain and pain mediator indexes were lower in the subxiphoid group (p<0.05 for all). The postoperative tumor recurrence rates were 3.70% and 20.37% in the subxiphoid and control groups, respectively (p=0.008). The five-year survival rates were 85.2% and 63.0% in the subxiphoid and control groups, respectively (p=0.008). Single-port thoracoscopy using the subxiphoid approach is technically feasible, safe, and effective in performing surgery for anterior mediastinal tumors with an intact capsule and a tumor diameter of ≤5 cm.

MP65-07 IMPACT OF SURGICAL INTERVENTION ON IRRADIATED PATIENTS' QUALITY OF LIFE

You have accessJournal of UrologyCME1 Apr 2023MP65-07 IMPACT OF SURGICAL INTERVENTION ON IRRADIATED PATIENTS' QUALITY OF LIFE Elizabeth Bearrick, Mazeed Aro-Lambo, Bridget Findlay, Paige Nichols, Katherine Anderson, and Boyd Viers Elizabeth BearrickElizabeth Bearrick More articles by this author , Mazeed Aro-LamboMazeed Aro-Lambo More articles by this author , Bridget FindlayBridget Findlay More articles by this author , Paige NicholsPaige Nichols More articles by this author , Katherine AndersonKatherine Anderson More articles by this author , and Boyd ViersBoyd Viers More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000003323.07AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: The impact of surgical intervention following radiation injury on patient quality of life (QOL) is not well studied. The objective of this study was to evaluate the effect of definitive surgical intervention on health burden and QOL among patients with a history of radiation. METHODS: Patients who underwent major intra-abdominal intervention to address radiation injury were included in the study (N=24). A validated 36-item short form (SF-36) survey was used to assess QOL domains (0-100, low-high) pre- and post-operatively. The scores obtained from these surveys were used to assess the difference in QOL before and after intervention across the group and on a per-individual basis (pairwise students-t). RESULTS: Median time from radiation to surgical intervention was 7.6 years. The etiology of radiation injury was urologic in 20(83%), colorectal in 2(8%), gynecologic in 2(8%). In total, 10(42%) patients had fistula and 8(33%) had strictures. In assessment of radiation injury burden on health in the year before surgery vs the year after, there was significantly greater hospitalizations (median 1 vs 0.5), hospitalized days (3.5 vs 0.5), and ER visits (1 vs 0; all p<0.05). There was no significant difference in hospitalizations or ER visits according to injury etiology. Pre- and post SF-36 survey was conducted a median 1.6 months prior to surgery and 5.1 months after. Figure 1. outlines the differences in pre- and post-operative QOL. Mean QOL scores improved in every domain following surgery, including physical functioning (54.6 vs 76.1), role limitations due to physical health (29.8 vs 55.6), role limitations due to emotional problems (47.4 vs 75.9), energy/fatigue (34.7 vs 55.6), emotional well-being (64.2 vs 80.1), social functioning (41.4 vs 81.3), pain (48.9 vs 78.2), and general health (45.8 vs 61.7) (all p<0.05). Per-individual pairwise comparisons were clinically significant except for physical health. CONCLUSIONS: Following definitive surgical intervention for radiation induced urinary injury there is a significant reduction in health-related complications and improved QOL across all measured domains. Such information may prove useful in directing earlier intervention and appropriately counseling patients. Source of Funding: None © 2023 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 209Issue Supplement 4April 2023Page: e893 Advertisement Copyright & Permissions© 2023 by American Urological Association Education and Research, Inc.MetricsAuthor Information Elizabeth Bearrick More articles by this author Mazeed Aro-Lambo More articles by this author Bridget Findlay More articles by this author Paige Nichols More articles by this author Katherine Anderson More articles by this author Boyd Viers More articles by this author Expand All Advertisement PDF downloadLoading ...

MP80-17 RACIAL DIFFERENCES IN PATIENT-REPORTED OUTCOMES AMONG MEN TREATED WITH RADICAL PROSTATECTOMY FOR PROSTATE CANCER

You have accessJournal of UrologyCME1 Apr 2023MP80-17 RACIAL DIFFERENCES IN PATIENT-REPORTED OUTCOMES AMONG MEN TREATED WITH RADICAL PROSTATECTOMY FOR PROSTATE CANCER Mara Koelker, Muhieddine Labban, Nicola Frego, Jamie Ye, Stuart R. Lipsitz, Harrison Taylor Hubbell, Maria Edelen, Dejan K. Filipas, Grant L. Steele, Kevin Salinas, Jonathan Makanjuola, Caroline M. Moore, Christian P. Meyer, Adam S. Kibel, Alexander P. Cole, and Quoc-Dien Trinh Mara KoelkerMara Koelker More articles by this author , Muhieddine LabbanMuhieddine Labban More articles by this author , Nicola FregoNicola Frego More articles by this author , Jamie YeJamie Ye More articles by this author , Stuart R. LipsitzStuart R. Lipsitz More articles by this author , Harrison Taylor HubbellHarrison Taylor Hubbell More articles by this author , Maria EdelenMaria Edelen More articles by this author , Dejan K. FilipasDejan K. Filipas More articles by this author , Grant L. SteeleGrant L. Steele More articles by this author , Kevin SalinasKevin Salinas More articles by this author , Jonathan MakanjuolaJonathan Makanjuola More articles by this author , Caroline M. MooreCaroline M. Moore More articles by this author , Christian P. MeyerChristian P. Meyer More articles by this author , Adam S. KibelAdam S. Kibel More articles by this author , Alexander P. ColeAlexander P. Cole More articles by this author , and Quoc-Dien TrinhQuoc-Dien Trinh More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000003357.17AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: We aim to evaluate differences in patient-reported outcomes (PROM) using the Expanded Prostate Cancer Index Composite for Clinical Practice (EPIC-CP) questionnaire to measure patient-reported health-related quality of life (QoL) after radical prostatectomy. METHODS: We retrospectively assessed prospectively collected patient-reported outcomes using EPIC-CP scores at a tertiary care center using the institutional electronic health record between 2015 and 2021 for men with prostate cancer undergoing radical prostatectomy. The primary endpoint was overall QoL scores. An imputed mixed linear regression model was used to examine the effect of covariates on the change in overall QoL scores. A pairwise comparison was used to estimate the mean QoL scores before surgery as well as 3 months, 6 months, 12 months, and 24 months after surgery for Non-Hispanic Black (NHB) and Non-Hispanic White (NHW) men. RESULTS: Our cohort consisted of 2,229 men that answered at least one EPIC-CP questionnaire before or after surgery of which 110 (4.94%) were NHB and 2,119 (95.07%) were NHW men. The worst QoL scores were reported 3 months after radical prostatectomy with an average score of 21.52 (95%CI 19.83-23.21). The QoL scores were worse for NHB vs. NWH with a difference of (2.34, 95%CI 0.36-4.31, p=0.02) at baseline, (4.36, 95%CI 2.29-6.42, p<0.01) at 3 months after surgery, and (3.26, 95%CI 1.10-5.43, p<0.01) 6 months after surgery (Figure 1). However, there was no difference in QoL between NHB and NWH men at 12 months and 24 months after surgery. CONCLUSIONS: We found that NHB had worse QoL score than NHW men before surgery, 3 months, and 6 months after surgery. However, there was no long-term difference in reported QoL between NHB and NHW men at 12 months and 24 months after surgery. Our findings can inform preoperative counseling of men undergoing radical prostatectomy. Further research is warranted to understand the racial differences in postoperative recovery after radical prostatectomy. Source of Funding: None © 2023 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 209Issue Supplement 4April 2023Page: e1159 Advertisement Copyright & Permissions© 2023 by American Urological Association Education and Research, Inc.MetricsAuthor Information Mara Koelker More articles by this author Muhieddine Labban More articles by this author Nicola Frego More articles by this author Jamie Ye More articles by this author Stuart R. Lipsitz More articles by this author Harrison Taylor Hubbell More articles by this author Maria Edelen More articles by this author Dejan K. Filipas More articles by this author Grant L. Steele More articles by this author Kevin Salinas More articles by this author Jonathan Makanjuola More articles by this author Caroline M. Moore More articles by this author Christian P. Meyer More articles by this author Adam S. Kibel More articles by this author Alexander P. Cole More articles by this author Quoc-Dien Trinh More articles by this author Expand All Advertisement PDF downloadLoading ...

MP65-08 EVALUATION OF FUNCTIONAL OUTCOMES AND QUALITY OF LIFE IN ELDERLY PATIENTS (≥75 Y.O.) UNDERGOING MINIMALLY INVASIVE RADICAL CYSTECTOMY WITH SINGLE STOMA URETEROCUTANEOSTOMY VS. BRICKER INTRACORPOREAL ILEAL CONDUIT URINARY DIVERSION

You have accessJournal of UrologyCME1 Apr 2023MP65-08 EVALUATION OF FUNCTIONAL OUTCOMES AND QUALITY OF LIFE IN ELDERLY PATIENTS (≥75 Y.O.) UNDERGOING MINIMALLY INVASIVE RADICAL CYSTECTOMY WITH SINGLE STOMA URETEROCUTANEOSTOMY VS. BRICKER INTRACORPOREAL ILEAL CONDUIT URINARY DIVERSION Antonio Luigi Pastore, Yazan AL Salhi, Andrea Fuschi, Alessia Martoccia, Fabio Maria Valenzi, Alessandro Sciarra, Stefano Salciccia, De Nunzio Cosimo, Andrea Tubaro, Costantino Leonardo, Giorgio Franco, Silvio Scalzo, Paolo Pietro Suraci, Onofrio Antonio Rera, and Antonio Carbone Antonio Luigi PastoreAntonio Luigi Pastore More articles by this author , Yazan AL SalhiYazan AL Salhi More articles by this author , Andrea FuschiAndrea Fuschi More articles by this author , Alessia MartocciaAlessia Martoccia More articles by this author , Fabio Maria ValenziFabio Maria Valenzi More articles by this author , Alessandro SciarraAlessandro Sciarra More articles by this author , Stefano SalcicciaStefano Salciccia More articles by this author , De Nunzio CosimoDe Nunzio Cosimo More articles by this author , Andrea TubaroAndrea Tubaro More articles by this author , Costantino LeonardoCostantino Leonardo More articles by this author , Giorgio FrancoGiorgio Franco More articles by this author , Silvio ScalzoSilvio Scalzo More articles by this author , Paolo Pietro SuraciPaolo Pietro Suraci More articles by this author , Onofrio Antonio ReraOnofrio Antonio Rera More articles by this author , and Antonio CarboneAntonio Carbone More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000003323.08AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Diversion after radical cystectomy (RC) is crucial when considering elderly subjects. Data on the quality of life (QoL) impact with different diversions is scarce. This study aims to compare complications and QoL in patients aged≥75 y.o., who underwent minimally invasive (MI) RC with Bricker intracorporeal urinary derivation and single stoma ureterocutaneostomy. METHODS: In this retrospective analysis, we investigated elderly patients who underwent MIRC and intracorporeal diversion. The 78 subjects were divided into two groups: group A, ileal conduit, and group B, single stoma ureterocutaneostomy. We evaluated the bowel's recovery time and complications rate. We investigated QoL 3 and 6 months after surgery using the Stoma-QoL questionnaire. RESULTS: Mean age was 77.2 in group A and 82.4 in group B. The mean ASA score and Charlson Comorbidity index were comparable between the two groups. Rates of complications were 57.6% and 37.4% in groups A and B, respectively. The mean postoperative Stoma-QoL score 3 months after surgery was 52.2 and 52.4 in groups A and B, respectively. At 6 months of follow-up the Stoma QoL mean score was 63.4, showing homogeneity between the groups. CONCLUSIONS: MIRC with single stoma ureterocutaneostomy represents an alternative to ileal conduit, with comparable QoL and ostomy management 6 months after surgery, reporting fewer complications especially in frail patients aged≥75 y.o. Source of Funding: None © 2023 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 209Issue Supplement 4April 2023Page: e893 Advertisement Copyright & Permissions© 2023 by American Urological Association Education and Research, Inc.MetricsAuthor Information Antonio Luigi Pastore More articles by this author Yazan AL Salhi More articles by this author Andrea Fuschi More articles by this author Alessia Martoccia More articles by this author Fabio Maria Valenzi More articles by this author Alessandro Sciarra More articles by this author Stefano Salciccia More articles by this author De Nunzio Cosimo More articles by this author Andrea Tubaro More articles by this author Costantino Leonardo More articles by this author Giorgio Franco More articles by this author Silvio Scalzo More articles by this author Paolo Pietro Suraci More articles by this author Onofrio Antonio Rera More articles by this author Antonio Carbone More articles by this author Expand All Advertisement PDF downloadLoading ...

Quality of Life in People With Unilateral Lower Limb Amputation at a Tertiary Rehabilitation Centre in Northern India: A Cross-Sectional Study.

Background and purpose The patients after amputation undergo a sudden transformation in their quality of life. In India, amputation done at the appropriate time is a rare phenomenon because usually, the patients present themselves at the later stages. The surgeons, however, while performing amputation surgeries, primarily consider saving the life of a patient under adverse conditions when patients report to them very late that the surgeries are carried out urgently. Assessing the quality of life (QOL) and the various sociodemographic factors affecting the QOL paves the way for future rehabilitation programs. Aims and objectives To evaluate the quality of life of subjects with unilateral lower limb amputation among the North Indian population. Materials and methods This cross-sectional study was conducted in the tertiary rehabilitation center. A total of 106 Subjects were recruited. Informed consent was taken. WHOQOL-BREF contains 26 items covering four important aspects of QOL. The WHOQOL-BREF self-administered free questionnaire was used as a data collection tool, and the Hindi version downloaded from the WHO website was also used for those who can't understand English. Results The range of the physical domain, psychological domain, social domain, and environmental domain were 0 and 100. The mean score of different QOL transformed domain scores (on a scale of 100) were 47.91±20.12, 57.37±20.46, 59.36±25.32 and 51.50±21.96, respectively. Trauma was the leading cause of amputation, followed by diabetes mellitus, cancer, peripheral vascular disease, and other causes. Transtibial amputees were more in number compared to transfemoral. The percentage of male and female amputees was 78.30%, and 21.70%, respectively. Conclusion The physical domain was the most affected domain, followed by the psychological, social, and environmental domains. A delay in the prosthesis fitment aggravates the physical burden of amputees. Early prosthesis & psychological counseling will improve the QOL significantly.

Investigation of Quality of Life After Coronary Artery Bypass Surgery: A 10-Year Long-Term Follow-Up Study

Background. Quality of life (QoL) is a multifactorial concept that is used to assess physical and mental health. This cross-sectional study administered the Short Form 36 Health Survey Questionnaire (SF-36) and a sociodemographic datasheet to evaluate the QoL of patients who underwent coronary artery bypass grafting (CABG).&#x0D; Aim. With this study, we aimed to determine the quality of life of patients who had open heart surgery years later.&#x0D; Methods. Patients who underwent elective isolated CABG from January to December 2011 in the cardiovascular disease’s clinic of a hospital in Eastern Turkey were recruited, after which data were collected from them via telephone and mail. One patient was contacted by mail, and 32 others were contacted by telephone. The data were examined through the analysis of numbers of percentages, mean values, and standard deviations. The Mann–Whitney U test, Kruskal–Walli’s test, and correlation analysis were also conducted.&#x0D; Results. Of the patients who underwent surgery, 33 responded to our survey. Their mean age was 69.03±10.91 years. The results showed that gender, marital status, and educational attainment affected the mean SF-36 scores of the participants (p &lt; 0.05) and that the mean QoL score of the patients was low.&#x0D; Conclusion. Considering the mean age of the respondents, studies that compare such patients with those who did not undergo surgery should be carried out.

QUALITY OF LIFE OF OLDER PEOPLE RESIDING IN A RURAL COMMUNITY AT BANKE DISTRICT, NEPAL

Background: The quality of life of older people reflects their health status and well-being and is an important area of concern for those involved in the care of older people. The objective of the study was to assess the quality of life of older people residing in a rural community at Banke district, Nepal. Methods: A cross-sectional study was conducted among 368 older people aged 60 years and above in ward number-3 (Karmona, Radhaypur, and Indrapur) of Janaki rural municipality of Banke district. Purposive sampling technique was used to recruit participants. Data were collected through face-to-face interviews using World Health Organization Quality of Life Scale- BREF. T-test and ANOVA test were used to compare the mean scores of different variables and domains of quality of life. The significance level was set at p &lt;0.05. Results: The mean score and standard deviation of total quality of life were 72.97±6.91. The mean quality of life score was lowest in the psychological domain (63.39±7.11) compared to environment (71.56±7.40), social (77.68±10.49), and physical domains (79.24±12.39). A statistically significant difference was observed on total quality of life scores between age groups (p=.001), sex (p=0.047), marital status (p=.001), occupation (p=.004), educational status (p=.001), living status (p=.007), source of livelihood (p=0.001), and physical health problems (p=.001) of older people. Conclusions: In older people, the psychological domain of quality of life necessitates particular attention along with their environment, social, and physical health.

Physical Activity, Mental Health, and Quality of Life among School Students in the Jazan Region of Saudi Arabia: A Cross-Sectional Survey When Returning to School after the COVID-19 Pandemic.

Increasing evidence suggests that physical activity (PA) can reduce depression and anxiety in adolescents. At the same time, quality of life (QoL) is sensitive to both mental health and PA, but little is known about the mechanism between these three variables among adolescents. This study aimed to assess the physical activity, mental health, and quality of life of school students when they returned to school after two years of distance learning in the Jazan region. This current investigation represented an observational cross-sectional survey conducted in January 2022 among a random sample of 601 students from intermediate and high schools in the Jazan region, Saudi Arabia. Three standardized questionnaires were used for data collection; the Arabic version of the Pediatric Quality of Life Inventory (PedsQL), Depression Anxiety Stress Scales (DASS21), and the Fels PAQ for children. The analysis revealed a moderate level of physical activity, decreased HRQoL, and symptoms of mental health problems (anxiety, depression, and stress) among the schools' students when they returned to school following COVID-19 lockdown. The overall Pediatric Quality of Life mean score was (81.4 ± 16.4), which differed significantly according to gender, age groups, and grade levels (p < 0.05 for all). There was a negative correlation between the overall quality of life and mental health domains. Sport was negatively correlated with mental illness symptoms and positively correlated (p < 0.05) with Pediatric Quality of Life. The regression models revealed that stress was a significant predictor for the quality of life of male and female adolescents ([β = -0.30, (95% CI (-0.59) to (-0.02), p < 0.05)] and [β = -0.40, (95% CI (-0.70) to (-0.01), p < 0.05)], respectively). The analysis revealed a moderate level of physical activity among the schools' students when they returned to school following COVID-19 lockdown. Children's involvement in physical activity was associated with improved quality of life and mental health. The results call for the need to develop appropriate intervention programs to increase school students' physical activity levels.

Comparing the effects of smartphone-based and face-to-face pulmonary rehabilitation education on caregiver burden and quality of life among the family caregivers of patients with chronic obstructive pulmonary disease: a randomized controlled field trial

BackgroundFunctional limitation among patients with chronic obstructive pulmonary disorder (COPD) and their dependence on their family caregivers (FCs) can significantly increase caregiver burden (CB) and reduce the quality of life (QOL) among FCs. Education of pulmonary rehabilitation (PR) to FCs is a strategy with potential positive effects on CB. This study was conducted to compare the effects of smartphone-based and face-to-face (FTF) PR education on CB and QOL among the FCs of patients with COPD.MethodsThis randomized controlled field trial was conducted in 2021–2022. Participants were purposefully selected from the PR unit of Khorshid comprehensive respiratory care clinic in Isfahan, Iran, and randomly allocated to a control and an intervention group. Participants in the control group received PR education in twelve 30–60-min FTF sessions held twice weekly in six consecutive weeks. Their counterparts in the intervention group received PR education for 6 weeks through an android application. The Zarit Burden Interview and the 12-item Short Form Health Survey (SF-12) were used for data collection before and immediately after the study intervention. The SPSS software (v. 24.0) was used to analyze the data through the independent-sample t, paired-sample t, chi-square, and Fisher’s exact tests.ResultsThe means of participants’ age was 47.7 ± 13.8 years in the control group and 44.1 ± 14.8 years in the intervention group. Most participants in these groups were female (82.9% vs. 71.4%). The pretest mean scores of CB and QOL were respectively 50.77 ± 10.64 and 27.82 ± 3.9 in the control group and 49.77 ± 7.65 and 26.71 ± 3.5 in the intervention group with no significant between-group difference (P > 0.05). At the posttest, these values were respectively 51.57 ± 7.32 and 27.74 ± 3.28 in the control group and 37.31 ± 6.95 and 34.37 ± 2.8 in the intervention group, and between-group differences were significant (P < 0.05). The mean scores of CB and QOL did not significantly change in the control group (P > 0.05), but respectively decreased and increased significantly in the intervention group (P < 0.05).ConclusionsSmartphone-based PR education is effective in significantly decreasing CB and improving QOL among the FCs of patients with COPD.Trial registrationIranian Registry of Clinical Trials IRCT20161203031200N3

The Effect of Religious-Spiritual Education and Care on the Life Quality of Iranian Elderly: A Systematic Review and Meta-Analysis.

Aging causes the reduction in physical and physiological strength and an increase in the odds of affliction with chronic physical and mental diseasesultimately affectingthe quality of life (QoL). So far, several primary studies have been conducted on the impact of religious-spiritual education and care on the QoL of the elderly. However, to the best of our knowledge, a study that compiles and represents these findings in a published paper is lacking. Therefore, the current study conducted a systematic review and meta-analysis to investigate the effect of religious-spiritual education and care on the QoL of the elderly population. To access studies related to the aim of the study, SID, MagIran, IranMedex, IranDoc, Embase, PubMed, Scopus, Web of Science, and Google Scholar databases were searched. The search was done using relevant and validated keywords with MeSH/Emtree without time limitations until December 2021. The qualitative appraisal of the papers was done using the JBI checklist. To estimate the heterogeneity of studies, I2 index was used, and to combine the data and carry out a meta-analysis, Random Effects model was used. In the primary research, 1065 studies were found. The omission of the redundant cases led to a total number of 12 papers with a sample size of 317 in the intervention group and 321 in the control to be included in the meta-analysis. After the intervention, the mean score of QoL showed a significant increase by 1.42 ± 0.31 with a Confidence Interval of 95% (P<0.001). Meta-regression results showed that the increase in the year of conducting the study, and the number of intervention sessions,that the standardized mean difference had a decreasing trend, and thatwith the increase in the average age of the elderly, there was a rising trend (P<0.001). Therefore, it seems that the application of religious-spiritual education and care could be part of aprogram to improve the QoL of the elderly.

Examining the relationship between health literacy and quality of life: evidence from older people admitted to the hospital

IntroductionLiteracy has become an increasingly serious problem, especially as it relates to health care. In this regard, health literacy (HL), as a cognitive skill, has proven to be an influential factor to improve of the quality of life (QOL). This study aimed to examine the level of HL and its relationship with the QOL of older people at the time of discharge from the hospital in the south of Iran.MethodsThis descriptive-analytical cross-sectional study included 300 older people admitted and treated in 10 teaching-therapeutic hospitals affiliated with the Shiraz University of Medical Sciences in 2021. The standard Health Literacy for Iranian Adults (HELIA) questionnaire and the World Health Organization Quality of Life Questionnaire (WHOQOL-BREF) were used to collect the required data. Data were analyzed with SPSS software version 23 software using descriptive and inferential statistics, Pearson’s correlation coefficient, T-test, ANOVA, and multiple linear regression at p = 0.05.ResultsThe mean scores of Hl and QOL for older people were 48.22 ± 9.63 (out of 100) and 61.59 ± 12.43 (out of 120), respectively. Moreover, there was a significant direct correlation between the participants’ HL and their QOL (r=0.388, p<0.001). All dimensions of HL, including comprehension (β=0.461, p<0.001), decision-making and behavior (β=0.434, p<0.001), access (β=0.397, p<0.001), reading skill (β=0.362, p=0.002), and assessment (β=0.278, p=0.004), were significant relationship with QOL. A statistically significant difference was revealed between the mean scores of HL regarding the participants’ gender (p=0.04) and level of education (p=0.001). Furthermore, the mean scores of QOL were significantly different with regard to older people’s gender (p=0.02), marital status (p=0.03), level of education (p=0.002), and income (p=0.01).ConclusionThe findings revealed the participants’ inadequate HL and average QOL. Considering the relationship of HL with QOL, it is recommended to develop comprehensive programs and effective interventions to develop HL skills and subsequently improve QOL among older people.

Quality of life of patients on Continuous Ambulatory Peritoneal Dialysis

End Stage Renal Disease (ESRD) is a serious medical disorder leading to impaired Quality oflife (QOL). QOL as perceived by patients with ESRD is an important measure of patient outcome. However, there is paucity of literature that assesses the QOL of patients on Continuous Ambulatory Peritoneal Dialysis (CAPD) in our country. A descriptive study was undertaken to assess the QOL of patients on CAPD and to determine the relationship between QOL and selected demographic and clinical variables. A total of 33 subjects were chosen by consecutive sampling technique. Data was collected using self-administered Questionnaire - Kidney Disease Quality of life (KDQOL-SF™ 1.3) questionnaire. The mean age was 53.06+80yrs and the most common cause of ESRD was chronic disease (66.7%) i.e. Diabetes mellitus (33.3%). The overall QOL was satisfactory (58.28+11.5). Highest mean QOL scores were in the area of dialysis staff encouragement (87.50), and symptoms (83.01). The lowest mean score of QOL was in the area of burden of kidney disease (32.27), and role physical (38.78). Highest QOL scores in the area of ‘dialysis staff encouragement’ emphasises on the role of nurses and health care team in optimising the QOL of patients on CAPD.

Quality of Life and Related Factors in Patients Undergoing Renal Replacement Therapy at the Hospital General Universitario de Ciudad Real: Cross Sectional Descriptive Observational Study.

Background: The aim of the present study was to determine the relationship between the quality of life of patients on renal replacement therapy and the Symptomatology they presented. Methods: Cross-sectional descriptive observational study: quality of life was assessed by means of the KDQOL-SF questionnaire, Symptomatology by the Palliative Care Outcome Scale-Symptoms Renal questionnaire, and sociodemographic and clinical data of patients in the Hemodialysis Unit (HD) of the Hospital General Universitario de Ciudad Real (HGUCR) by means of personal interviews and clinical history data. Results: A total of 105 patients participated in the study, 63 (60.57%) men and 42 (40.38%) female. The mean age was 62.5 dt (14.84) years. Of these, 43 (41%) were on peritoneal dialysis and 62 (59%) were on hemodialysis. The mean quality of life score was 44.89 dt (9.73). People on hemodialysis treatment presented a better quality of life than those on PD treatment: 49.66 dt (9.73) vs. 38.13 dt (9.12) t = 7.302, p < 0.001. A higher score on the symptom impairment scale (post-renal) correlated with worse scores on the total quality of life score: r = -0.807, p < 0.001. It was observed that those who improved the distress symptom scored better on the total quality of life questionnaire: 50.22 dt (8.44) vs. 46.42 dt (9.05), p < 0.001. Conclusions: The presence and management of the large number of symptoms that appear as side effects, such as distress or depression, could determine changes in some components of quality of life.

Quality of life associated with immunosuppressant treatment adherence in liver transplant recipients: A cross-sectional study.

Purpose: Transplanted organ survival after solid organ transplantation highly correlates with the adherence levels of the patients to their immunosuppressive drugs. On the other hand, one of the main goals of liver transplantation is to increase the overall quality of life (QOL) for the patient. This study is aimed to analyze the relationship between adherence and QOL in adult liver transplant recipients of the biggest liver transplant center in Asia. Methods: All of the included patients were older than 18 years and at least 6 months had passed from their liver transplantation. The adherence level was measured with BAASIS method and the QOL was assessed by SF-36 questionnaire in real-time interviews. The relationship between adherence and different aspects of QOL in addition to qualitative and quantitative influential factors on these two outcomes was calculated with statistical analysis. Results: Among the 122 included patients, 41% of the were categorized in the non-adherent group. The most important reasons for non-adherence in these patients included forgetfulness (62%), lack of medication (12%), financial problems for drug supply (9%), and side effects (2%). According to the results of the multivariate linear regression model, rejection was the only influential factor in the occurrence of non-adherence among patients (OR = 8.226 CI (1.404-48.196)). The overall mean QOL score of patients was reported 51.09 ± 21.86. The lowest is given to social functioning, while mental health has achieved the highest score. The mean QOL scores in different dimensions in patients with adherence were higher than non-adherents, which was only significant in mental health (p-value = 0.01). Additionally, in total scores related to Physical Composite Score (PSC) and Mental Composite Score (MCS), the mean MSC scores in adherent patients were significantly higher than non-adherent patients (p-value: 0.02). Although adherent patients have an overall greater QOL, the only meaningful effect on QOL total score was from income level. Conclusion: The overall QoL score has been in all parameters higher in the adherent group compared with non-adherent patients. The difference in QoL was most meaningfully significant in mental composite score among other parameters of QoL.

Long-term postoperative quality of life in childhood survivors with cerebellar mutism syndrome.

To investigate the long-term quality of life (QoL) of children with cerebellar mutism syndrome (CMS) and explore the risk factors for a low QoL. This cross-sectional study investigated children who underwent posterior fossa surgery using an online Pediatric Quality of Life Inventory questionnaire. CMS and non-CMS patients were included to identify QoL predictors. Sixty-nine patients were included (male, 62.3%), 22 of whom had CMS. The mean follow-up time was 45.2 months. Children with CMS had a significantly lower mean QoL score (65.3 vs. 83.7, p < 0.001) and subdomain mean scores (physical; 57.8 vs. 85.3, p < 0.001; social: 69.5 vs. 85.1, p = 0.001; academic: p = 0.001) than those without CMS, except for the emotional domain (78.0 vs. 83.7, p = 0.062). Multivariable analysis revealed that CMS (coefficient = -14.748.61, p = 0.043), chemotherapy (coefficient = -7.629.82, p = 0.013), ventriculoperitoneal (VP) shunt placement (coefficient = -10.14, p = 0.024), and older age at surgery (coefficient = -1.1830, p = 0.007) were independent predictors of low total QoL scores. Physical scores were independently associated with CMS (coefficient = -27.4815.31, p = 0.005), VP shunt placement (coefficient = -12.86, p = 0.025), and radiotherapy (coefficient = -13.62, p = 0.007). Emotional score was negatively associated with age at surgery (coefficient = -1.92, p = 0.0337) and chemotherapy (coefficient = -9.11, p = 0.003). Social scores were negatively associated with male sex (coefficient = -13.68, p = 0.001) and VP shunt placement (coefficient = -1.36, p = 0.005), whereas academic scores were negatively correlated with chemotherapy (coefficient = -17.45, p < 0.001) and age at surgery (coefficient = -1.92, p = 0.002). Extent of resection (coefficient = 13.16, p = 0.021) was a good predictor of higher academic scores. CMS results in long-term neurological and neuropsychological deficits, negatively affecting QoL, and warranting early rehabilitation.

Homecare patients’ quality of life and the burden of family caregivers: a descriptive cross-sectional study

ABSTRACT The aim of the present study is to evaluate the quality of life of homecare patients and the burden of their family caregivers. The study was conducted in the home health care unit of a state hospital using a descriptive cross-sectional design. The data were collected from patients (n = 105) who agreed to participate in the study and their family caregivers (n = 105). The mean quality of life score of homecare patients was 68.15 ± 9.90 (M ± SD). The mean caregiving burden score was estimated to be at a moderate/high level with a value of 53.72 ± 13.30. A significant moderate negative correlation was found between the homecare patients’ quality of life and caregiver burden (r = −0.649; p < .05). The finding that higher family caregiver burden was associated with lower quality of life among homecare patients suggests that health professionals approach homecare patients together with their family caregivers.

Clinical and Patient reported outcomes following open reduction and internal fixation for distal tibial intra-articular fractures

IntroductionIntra-articular distal tibial plafond fractures are rare injuries, provide a challenge for the surgeon and can often have poor outcomes. The aim of this paper was to report long term patient reported functional outcomes, health related quality of life (QoL) scores and rates of complications in order to fully counsel the patient on likely outcomes and set realistic post-operative expectations for the patient. MethodsWe conducted a retrospective review of 20 patients with distal tibial intra-articular fractures that presented to our institution between September 2014 and September 2020. All patients underwent open reduction and internal fixation (ORIF). Clinical, radiological and patient reported outcome measures (PROMS), quality of life (QoL) scores and complications were collected. ResultsThe mean age of the patients at the time of surgery was 50.6 years (24−71). There were 7 males and 13 females. There were 4 open and 16 closed fractures. There were 7 Rüedi and Allgöwer (RA) Type 1, 9 Type 2 and 4 Type 3 fractures. The mean follow-up was 3.8 years [1–7]. The mean OMAS score was 54.3, reaching a peak at 2 years from injury. The mean QoL score (EQ5D5L) was 0.602, representing only 70 % of aged matched, UK population based norms. ConclusionsWhilst clinical outcomes are comparable with other studies, this report highlights this is a devastating injury, with most people taking 2 years to reach peak recovery. QoL outcome scores only reach 70 % normal and only 35 % of patients return to within 10 % of age matched population based norms.

Assessment of quality of life in children with epilepsy in Oman

PurposeThe study aims to describe the quality of life (QoL) in Omani children with epilepsy at Sultan Qaboos University Hospital, Oman.MethodsOne hundred and one Omani children, with an age range from 5 to 18 years, diagnosed with epilepsy were enrolled in the study over 3 months. Descriptive epidemiology was used to characterize QoL in these children. QoL was measured using the PedsQL (4.0) questionnaire, a 23-item child and parent report questionnaire. Analysis of variance (ANOVA) was used to compare mean QoL scores, and agreement between the QoL reports of children and parents was evaluated using Spearman’s rho; while, Multivariate analysis of variance (MANOVA) was performed to determine differences in subscale ratings.ResultsFactors affecting QoL included family status, income level, social security coverage, type of treatment, seizure frequency, age of onset, and seizure-free duration in years. Children between 5 and 7 years and females, in general, were most affected, as reflected by the overall QoL subscale. Consistency between the children's self-reports and parent proxy reports on the PedsQL™ was moderate to low.ConclusionOmani children with epilepsy have poor QoL, and their psychosocial function is severely affected. Therefore, QoL should be an important outcome measure in managing children with epilepsy rather than just seizure control.

Effectiveness of Symptom Management Intervention for Improving the QOL of Cancer Patients.

Managing the symptoms of cancer patients is challenging for health care providers and interventions individually designed are required to improve the quality of life (QOL) of cancer patients. to assess the efficacy of symptom management intervention on symptom reduction and the QOL of cancer patients. A Quasi-experimental study using pre and post-test design was conducted among 200 cancer patients selected by a convenient sampling technique from the selected cancer hospitals. The intervention group received symptom management intervention and the control group received routine clinical care. The data were collected from individuals who had been diagnosed with breast/head and neck cancer and were in the third or fourth stages of cancer, using symptom assessment and Functional Assessment of Cancer Therapy (FACT) QOL tool. After the pre-test, symptom management intervention was provided, and a post-test was conducted at one month and three months after the intervention. The mean age was 50.93 years among the participants. Fifty-two percent and 68% of them were in stage IV cancer in the intervention group and control group respectively. The mean QOL score of head and Neck cancers in the intervention group increased from 20.76 (1.82) to 97.03 (3.33) and the mean scores of QOL of breast cancer patients in the intervention group increased from 22.44 (2.92) to 94.39 (8.30). Repeated measure ANOVA showed that the intervention program was effective in enhancing symptom reduction and QOL among cancer patients (Head and Neck cancers F(1.3, 114) =391.62, p< 0.001 and Breast cancer F (1, 75) =177.41.41, p=.001). Nurses play a vital role in providing care to cancer patients and improving their quality of life since nurses are more involved in care.