MP80-17 RACIAL DIFFERENCES IN PATIENT-REPORTED OUTCOMES AMONG MEN TREATED WITH RADICAL PROSTATECTOMY FOR PROSTATE CANCER

Abstract

You have accessJournal of UrologyCME1 Apr 2023MP80-17 RACIAL DIFFERENCES IN PATIENT-REPORTED OUTCOMES AMONG MEN TREATED WITH RADICAL PROSTATECTOMY FOR PROSTATE CANCER Mara Koelker, Muhieddine Labban, Nicola Frego, Jamie Ye, Stuart R. Lipsitz, Harrison Taylor Hubbell, Maria Edelen, Dejan K. Filipas, Grant L. Steele, Kevin Salinas, Jonathan Makanjuola, Caroline M. Moore, Christian P. Meyer, Adam S. Kibel, Alexander P. Cole, and Quoc-Dien Trinh Mara KoelkerMara Koelker More articles by this author , Muhieddine LabbanMuhieddine Labban More articles by this author , Nicola FregoNicola Frego More articles by this author , Jamie YeJamie Ye More articles by this author , Stuart R. LipsitzStuart R. Lipsitz More articles by this author , Harrison Taylor HubbellHarrison Taylor Hubbell More articles by this author , Maria EdelenMaria Edelen More articles by this author , Dejan K. FilipasDejan K. Filipas More articles by this author , Grant L. SteeleGrant L. Steele More articles by this author , Kevin SalinasKevin Salinas More articles by this author , Jonathan MakanjuolaJonathan Makanjuola More articles by this author , Caroline M. MooreCaroline M. Moore More articles by this author , Christian P. MeyerChristian P. Meyer More articles by this author , Adam S. KibelAdam S. Kibel More articles by this author , Alexander P. ColeAlexander P. Cole More articles by this author , and Quoc-Dien TrinhQuoc-Dien Trinh More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000003357.17AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: We aim to evaluate differences in patient-reported outcomes (PROM) using the Expanded Prostate Cancer Index Composite for Clinical Practice (EPIC-CP) questionnaire to measure patient-reported health-related quality of life (QoL) after radical prostatectomy. METHODS: We retrospectively assessed prospectively collected patient-reported outcomes using EPIC-CP scores at a tertiary care center using the institutional electronic health record between 2015 and 2021 for men with prostate cancer undergoing radical prostatectomy. The primary endpoint was overall QoL scores. An imputed mixed linear regression model was used to examine the effect of covariates on the change in overall QoL scores. A pairwise comparison was used to estimate the mean QoL scores before surgery as well as 3 months, 6 months, 12 months, and 24 months after surgery for Non-Hispanic Black (NHB) and Non-Hispanic White (NHW) men. RESULTS: Our cohort consisted of 2,229 men that answered at least one EPIC-CP questionnaire before or after surgery of which 110 (4.94%) were NHB and 2,119 (95.07%) were NHW men. The worst QoL scores were reported 3 months after radical prostatectomy with an average score of 21.52 (95%CI 19.83-23.21). The QoL scores were worse for NHB vs. NWH with a difference of (2.34, 95%CI 0.36-4.31, p=0.02) at baseline, (4.36, 95%CI 2.29-6.42, p<0.01) at 3 months after surgery, and (3.26, 95%CI 1.10-5.43, p<0.01) 6 months after surgery (Figure 1). However, there was no difference in QoL between NHB and NWH men at 12 months and 24 months after surgery. CONCLUSIONS: We found that NHB had worse QoL score than NHW men before surgery, 3 months, and 6 months after surgery. However, there was no long-term difference in reported QoL between NHB and NHW men at 12 months and 24 months after surgery. Our findings can inform preoperative counseling of men undergoing radical prostatectomy. Further research is warranted to understand the racial differences in postoperative recovery after radical prostatectomy. Source of Funding: None © 2023 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 209Issue Supplement 4April 2023Page: e1159 Advertisement Copyright & Permissions© 2023 by American Urological Association Education and Research, Inc.MetricsAuthor Information Mara Koelker More articles by this author Muhieddine Labban More articles by this author Nicola Frego More articles by this author Jamie Ye More articles by this author Stuart R. Lipsitz More articles by this author Harrison Taylor Hubbell More articles by this author Maria Edelen More articles by this author Dejan K. Filipas More articles by this author Grant L. Steele More articles by this author Kevin Salinas More articles by this author Jonathan Makanjuola More articles by this author Caroline M. Moore More articles by this author Christian P. Meyer More articles by this author Adam S. Kibel More articles by this author Alexander P. Cole More articles by this author Quoc-Dien Trinh More articles by this author Expand All Advertisement PDF downloadLoading ...