In this paper, A miniaturized dual-band implantable antenna using meandered line resonator is proposed for bio-telemetry applications. The proposed antenna has dual-band (0.91 GHz and 2.45 GHz) operation, covering the important Industrial, Scientific and Medical (ISM) bands. Miniaturization is achieved using meandered resonator and a square slot etched in the ground plane. The performance of the proposed antenna inside a quasi-implantable biomedical device (IBD) is analysed in a homogeneous skin model, human intestine and human head. The measurements are performed by implanting the quasi-IBD inside a saline solution and minced pork meat. The quasi-IBD consists of the proposed antenna, batteries and printed circuit board (PCB) with electronic components on it. The proposed antenna has compact dimensions of 5.6 ×5.8× 0.25 mm3. The measured peak gains in the minced pork meat are −22.9 dBi and −22.1 dBi at 0.91 GHz and 2.45 GHz, respectively. The low specific absorption rate (SAR) of the proposed antenna allows maximum input power of 3.32 mW at 0.91 GHz and 4.37 mW at 2.45 GHz. To the best of the authors’ knowledge, this is the most compact dual-band implantable antenna reported in the literature for 0.91 GHz and 2.45 GHz ISM bands.