This study establishes a life cycle assessment model to quantitively evaluate and predict material resource consumption, fossil energy consumption and environmental emissions of plug-in hybrid electric vehicles (PHEVs) by employing the GaBi software. This study distinguishes the environmental impact of different vehicle working conditions, power battery degradation scenarios, and mileage scenarios on the operation and use stages of PHEVs, BEVs, and HEVs. The findings indicate that under urban, highway, and aggressive driving conditions, PHEVs’ life cycle material resource and fossil fuel consumption exceed that of BEVs but are less than HEVs. Battery degradation leads to increased material resource consumption, energy use, and environmental emissions for both PHEVs and BEVs. When the power battery degrades to 85%, the material resource and fossil energy consumption during the operation and use phase increases by 51.43%, 72.68% for BEVs and 29.37%, 36.21% for PHEVs compared with no degradation, respectively, indicating that the environmental impact of BEVs are more sensitive than those of PHEVs to the impact of power battery degradation. Among different mileage scenarios, PHEVs demonstrate the lowest sensitivity to increased mileage regarding life cycle material resource consumption, with the smallest increase. Future projections for 2025 and 2035 suggest life cycle GWP of HEV, PHEV and BEV in 2035 is 1.21 × 104, 1.12 × 104 and 1.01 × 104 kg CO2-eq, respectively, which shows reductions of 48.7%, 30.9% and 36.1% compared with those in 2025. The outcomes of this study are intended to bolster data support for the manufacturing and development of PHEV, BEV and HEV under different scenarios and offer insights into the growth and technological progression of the automotive sector.