Increasing pressures from stakeholders, government and non-government agencies are forcing the industries to implement Green Supply Chain Management (GSCM) initiatives. A successful implementation of GSCM is important for industries to increase economic-environmental performances and to ensure sustainability in business. The prime objective of this research is to evaluate the important factors associated with the successful implementation of GSCM. This paper proposes a Decision Making Trial and Evaluation Laboratory (DEMATEL) approach to develop a structural model for evaluating the influential factors among recognized factors. The proposed DEMATEL method enables to study the interrelationship between the evaluated factors through a causal diagram. To show the real-life applicability of the proposed DEMATEL based model, an empirical case studyof an Indian manufacturing company is conducted. Research findings indicate that Top Management Commitment, Human Technical Expertise, Financial Factors, has obtained the highest influential power for accomplishing the successful GSCM adoption. Conclusions and implications for managers are also discussed.