The study sought to assess the level of awareness regarding osteoarthritisand itsmanagement. This study was cross-sectional, using data from a sample of389individualsfromthecentral regionofSaudi Arabia. The participants completed an online questionnaireand ensured anonymity. Results:A total of 389 participants made up the sample for this study, which had a predominance offemales (56.6%, n=220), a majorityaged <50 years(66.6%, n=259),and most of them (51.7%, n=201) weighing 60-80 kg, substantialproportionlived in the Riyadh region (27.5%, n=107), with more than half (59.4%, n=231) havingauniversity education and working in offices (28.3%, n=110). The majority(73.3%, n=285) of participants were married, andavast majority (87.9%, n=342) were not smokers. The findings revealed that only 32.9%(n=128)of the participants had good knowledge about osteoarthritis. The studyfound thatstiffness (80.2%, n=312) and swelling (97.9%,n = 381) arethe most common signs and symptoms of osteoarthritis; the risk factorsforosteoarthritis were genetic factors (79.7%, n=310) and age (91.3%, n=355). The treatment of osteoarthritis identified in the studyincludedexercisessuch as swimming (85.1%, n=331), physical therapy (86.6%, n=337),and joint replacement surgery (92.0%, n=358). The study establishedastatistically significant association between age, education level, previous diagnosis of osteoarthritis,family history of osteoarthritis (p=0.004, 0.001, 0.002,and 0.001,respectively),andlevel of knowledge aboutosteoarthritis. However, therewasno statistically significant association between gender, marital status, smoking status, previous knee injuries, physical activity level, and the level of knowledge aboutosteoarthritis(p>0.05). Conclusion: Overall, the study revealed that 32.9% (n=128) of the participants had good knowledge about osteoarthritis. Participants aged 50-60 years, those with a university and post-graduate level of education, as well as those who had a previous diagnosis of osteoarthritis and those with a family history of osteoarthritis, had greater and better knowledge and awareness about osteoarthritis. Joint stiffness and swelling were identified, as the most common signs and symptoms of osteoarthritis. The risk factors identified in the study were genetic factors and age, while the treatment options noted by the study were exercise, such as swimming, physical therapy, and joint replacement surgery. The study notes the need for enhanced public awareness of the problems associated with osteoarthritis among the Saudi Arabian population.