“Ayurveda, the ancient Indian system of medicine, elucidates a comprehensive framework for understanding the pathogenesis and progression of diseases. A critical concept within this framework is the “Shatkriya kala”, explained by Acharya Sushruta which describes the six stages of disease development. These stages- Sanchaya, Prakopa, Prasara, Sthana Samshraya, Vyakta, Bheda- offer insight into the dynamic process of disease evaluation and guide timely intervention. It shows the stepwise progression of Dosha and Rogas. A clear understanding about the consecutive stages of disease, early diagnosis, prognosis, to adopt preventive and curative measures in Ayurvedic Pathology, the Shatkriya kala becomes essential. Likewise, understanding and inervening at the appropriate stages of Shatkriya Kala is crucial for the effective management and treatment of Amavata. In Ayurveda, Amavata is a debilitating condition compared to Rheumatoid Arthritis in modern, characterised by the accumulation of Ama(toxins) and the aggravation of Vata dosha. So, through this article, an attempt is made to highlight the importance of Shatkriya kala in the context of Amavata.