Management Of Amavata Research Articles

Importance of Shatkriya Kala in the Manifestation and Management of Amavata

“Ayurveda, the ancient Indian system of medicine, elucidates a comprehensive framework for understanding the pathogenesis and progression of diseases. A critical concept within this framework is the “Shatkriya kala”, explained by Acharya Sushruta which describes the six stages of disease development. These stages- Sanchaya, Prakopa, Prasara, Sthana Samshraya, Vyakta, Bheda- offer insight into the dynamic process of disease evaluation and guide timely intervention. It shows the stepwise progression of Dosha and Rogas. A clear understanding about the consecutive stages of disease, early diagnosis, prognosis, to adopt preventive and curative measures in Ayurvedic Pathology, the Shatkriya kala becomes essential. Likewise, understanding and inervening at the appropriate stages of Shatkriya Kala is crucial for the effective management and treatment of Amavata. In Ayurveda, Amavata is a debilitating condition compared to Rheumatoid Arthritis in modern, characterised by the accumulation of Ama(toxins) and the aggravation of Vata dosha. So, through this article, an attempt is made to highlight the importance of Shatkriya kala in the context of Amavata.

A REVIEW ON ROLE OF VIRECHANA IN AMAVATA

Amavata is made up of two words: Ama and Vata. It is a condition caused by the accumulation of Ama and Vata, and it resembles rheumatoid arthritis (RA) in modern parlance. Shodhana treatments are advised in Ayurveda whereas anti-inflammatory, analgesics, steroids, and disease-modifying anti-rheumatic drugs are required for its management as per modern medicine, which are not free from side effects. When Ama and Vata get vitiated consecutively and get deposited in the Koshtha, Trik and Sandhi where they produce Shotha, Shoola, and Stabdhata then the term is known as Amavata. Due to impaired Jatharagni, the Aahar rasa formed is Apakva. This Apakva Aahar rasa thus formed is in the Ama stage, which causes Sarvadoshaprakopa. Ancient Acharyas of Ayurveda have described the sequential employment of Deepana, Pachana, Shodhana, and Shamana therapies in the management of Amavata. According to Acharya Sharangdhara, Virechana is indicated in diseases arising from increased Pitta, and Ama in diseases like udara roga, adhman, for clearing kostha. In Amavata, the main causative factor of disease is Ama. Virechana helps to normalise the pratiloma gati of Vata, which produces symptoms like Anaha, Antrakujana, Vibandha, Kukshikathinya, and Kukshi shoola.

AYURVEDIC MANAGEMENT OF RHEUMATOID ARTHRITIS WSR TO AMAVATA- A CASE REPORT

Introduction: The Ayurveda described Mandagni as the root cause of all the diseases. The Acharyas mentioned Amavata as one of the common disorders caused by the impairment of Agni, formation of Ama and vitiation of Vata Dosha. The Ama is carried by the vitiated Vata and deposited in Shleshmasthanas producing symptoms like Angmarda, Aruchi, Alasya, Sandhiruk and Sandhishoth. On the basis of sign and symptoms Amavata can be equated to Rheumatoid Arthritis in modern era. Rheumatoid arthritis is a systemic autoimmune disease characterised by inflammatory arthritis and extra articular involvement. The onset of disease, beginning with prodrome of fatigue, weakness, joint stiffness, vague arthralgias followed by pain and swelling of joints. Aim: To evaluate the efficacy of Oral Ayurvedic drugs in management of Amavata. Method: In the present case, a female patient aged 36 years presented in OPD Of Asthi-SandhirogaVibhaga of RGGPG Ayurvedic College Paprola Distt. Kangra (H.P.) with the complaints of pain in multiple joints since 2 years. She also complained of generalised weakness and morning stiffness. The investigations were advised and oral Ayurvedic formulations like Vishtindukvati, Amavatari Ras and TrikatuChurna were prescribed to the patient. Result: The Ayurvedic management showed desired results in relieving the symptoms of patient. Discussion: The Ayurvedic drugs are effective in treating Amavata equated to RA and better alternative to NSAIDS, DMARDS and steroids in Rheumatoid arthritis management in todays world.

A Comparative Study to assess the Treatment Cost of Ayurvedic Medicine (Ginger and Castor Oil) and Modern Medicine (DMARDs) in Amavata (Rheumatoid Arthritis)

Ama and Vata are the initial elements in the pathophysiology of Tridosha, whereas Amavata is a result of their vitiation. The expense of treatment is a major factor in the economic burden of RA for both the patient and the health and social care systems. Objective: a. To assess the socio-demographic conditions of the patients of Amavata. b. To compare the cost of a one-month treatment of ginger and castor oil with DMARD in the management of Amavata. Methodology: Total 72 patients of RA Fulfilling the inclusion criteria and having symptoms of RA were enrolled for this Interventional study. Patients were treated in two different groups- Group A- 36 clinically diagnosed and registered patients of Amavata were treated by DMARD Group B- 36 clinically diagnosed and registered patients of Amavata were treated with ginger and castor oil. After the completion of the study, total 62 patients came after one month of treatment, so we included 62 patients in this study. 32 patients in group A and 30 patients in group B Results: The average direct cost of treatment of RA patients in 2024 was estimated as Rs. 2669.17 ($31.96)/month in group A (DMARD Group) and Rs. 1386.69 ($16.62) in group B (Ginger and Castor oil). Major part of total direct costs was covered by medicines (Rs. 1583) in group A and Laboratory cost (Rs. 600) in group B. The ratio of one-month cost of DMARD and Ayurvedic medicine (ginger and castor oil) was 12:1. Discussion: The cost of Ayurvedic medicine was very low in comparison to DMARD. Ayurvedic Medicine ginger and castor oil were easily available, safe, effective and cheap.

A Case Study on Bala Amavata w.s.r. to Juvenile Rheumatoid Arthritis

Introduction: Amavata is one of the most difficult to cure (Krichhrasadhya) diseases mentioned in Ayurveda. The main pathological factor in the development of this disease is “Ama”. This Ama is carried by “Vata” and travels throughout the body and gets lodges in the joints, which is the seat of “Kapha”. Accumulation of Ama in all the joints, results in Shotha (edema), Shoola (pain) and Stabdhata (stiffness) in the joints. Clinically, it is closely related to Rheumatoid Arthritis, which is a chronic inflammatory autoimmune disease involving multiple joints of the body. Methodology: A 13years boy with multiple joint pain, diagnosed as Amavata treated with Ayurvedic treatment modalities like Patrapinda Sweda and Virechana. Result: Remarkable improvement was noticed in pain, swelling, morning stiffness and restricted joint movement within first two months. Discussion: In modern medicine, the treatment of this disease includes steroids and Immunomodulator drugs together with non-steroidal anti-inflammatory drugs (NSAIDs), which acts as only Symptomatic treatment, whereas Virechana karma is one of the important bio-purificative methods which is indicated for complete elimination of Dushita Doshas and Ama from the body. Hence this article highlights on the importance of Ayurvedic treatment in the management of Amavata (Rheumatoid Arthritis).

A Review Article on the Role of Ingredients of <i>Kshara Vasti</i> (Medicated Enema) on Gut Microbiota of Rheumatoid Arthritis Patients

Kshara Vasti (medicated enema) is an important treatment in the management of Amavata which is correlated with Rheumatoid Arthritis (RA). The ingredients of Kshara Vasti have the property to act against Ama which is a root cause of the development of the disease. The main aim of this review is to study the role of ingredients of Kshara Vasti on the gut microbiota of RA patients. Jaggery, tamarind and rock salt have been proven to have a positive effect on the gut microbiome by enhancing the abundance of health-promoting species. Cow’s Urine (CU)/Cow Urine Distillate (CUD) enhances the bioavailability and efficacy of a drug with which it is co-administered. Anethum sowa has a significant impact on caecal microbiota. The production of Short-Chain Fatty Acids (SCFAs ) by Gut Microbiota (GM) may be a probable mode of action for the suppression of inflammatory conditions like RA. Each constituent in Kshara Vasti has a positive impact on modulating gut microbiota.

A Randomised Comparative Clinical Study to Evaluate the Efficacy of Sadhyovirechana with Gandharvahastadi Eranda Taila followed by Agnilepa and Dhanyamla Dhara in the Management of Amavata

Amavata is a Kruchrasadya vyadhi caused due to formation of Ama, vitiation of Vata and Agni vaishamya. Madhavakara mentions it as a ‘Sa kashtah sarva roganam’. Amavata is an Ama pradhana vyadhi, it requires Ama pachana as primary management. Hence in the present study, Sadhyovirechana as Abhyantara Shodhana Chikitsa followed by Bahya chikitsa in the form of Agnilepa and Dhanyamla Dhara in two different groups were used to evaluate their efficacy in the management of Amavata. Aims and Objectives: 1. To evaluate the efficacy of Sadhyovirechana with Gandharvahastadi Eranda Taila followed by Agnilepa in Amavata. 2. To evaluate the efficacy of Sadhyovirechana with Gandharvahastadi Eranda Taila followed by Dhanyamla dhara in Amavata. 3. To compare the efficacy of both the groups in Amavata. Methods: This is a comparative clinical study with pre-test & post-test design where in 40 patients diagnosed with Amavata of either sex were randomly assigned into two groups viz., Group A & Group B. Intervention: Group A: Sadhyovirechana on 1st day followed by Agnilepa for next 7 days. Group B: Sadhyovirechana on 1st day followed by Dhanyamla Dhara for next 7 days. Results: The effect of the treatment in both the groups were assessed by applying Wilcoxon’s rank sum test within the groups and Mann-Whitney U test between the groups, it showed that Group A showed better results than Group B. Conclusion: It can be concluded from the study that in the management of Amavata, Sadhyovirechana followed by Agnilepa and Dhanyamala Dhara Chikitsa drugs and procedures of both the groups are highly effective in treating Amavata.

Management of amavata (rheumatoid arthritis) with Virechana karma: A review article

Management of amavata (rheumatoid arthritis) with Virechana karma: A review article

Ayurvedic intervention in the management of Amavata (Rheumatoid Arthritis): A Case Series

The present case series documents the successful management of five cases of confirmed Amavata (Rheumatoid Arthritis). A retrospective analysis of five patients with Rheumatoid Arthritis (RA) symptoms was conducted in this study at the Arogyashala Rugnalaya Panchavati Nashik, Maharashtra. The patients were between the age of 39 to 70 years, were diagnosed as RA positive through a blood investigation, in July-August 2023, and were managed through Ayurveda interventions. The interventions include Anshanrupi Langhana (Fasting), Sunthisiddha Jala (Medicated water) in a dosage of 250-500 ml a day, Ruksha Waluka Pottali Swedana (Dry steam), and Shothahara Lepa (Medicinal paste) were prescribed for five days. Symptomatic assessment was done every day and blood investigations were conducted after 5 days. Significant relief in all the cases was observed as per RA classification criteria 2010 and DAS28-P index scores. However, large-scale randomized controlled trials are required to further validate the same.

A Comparative Clinical Study to Evaluate the Effect of Vatari Guggulu and Shatpushpadi Churna with Simhanada Guggulu in the Management of Amavata w.s.r. to Rheumatoid Arthritis

The disease Amavata described in classical Ayurvedic literature is closely resembles with Rheumatoid Arthritis (RA). Amavata is a crippling condition where simultaneously aggravated Vata and Ama associated with each other settles in Sandhis and produce Sandhishoola, Sandhishotha, Sparshaasahitwa, which is similar to Rheumatoid Arthritis. Amavata is the challenging problem for medical science with different treatment protocol. The objectives of this randomized parallel group Comparative study were to evaluate the effect of Vatari Guggulu and Shatpushpadi Churna with Simhanada Guggulu in the management of Amavata w.s.r. to Rheumatoid Arthritis This Study was conducted on 32 patients selected randomly from OPD and IPD of R.G.G.P.G. Ayurvedic College and Hospital, Paprola, Dist. Kangra (H.P.) and divided into 2 groups. Group I and Group II having 16 patients in each group. Group A were managed with Vatari Guggulu 500mg BD with lukewarm water and Shatpushpadi Churna 3gm BD with lukewarm water while Group B were managed with Simhanada Guggulu 500mg BD with lukewarm water for 6 weeks. Results showed statistically significant difference in effect of Group I and Group II on subjective parameters – Angamarda, Trishna, Apaka, Jadya, Sparsh Ashyata, Vidvibandha, Nidravipraya, ESR, walking time and grip strength. Percent wise Vatari Guggulu and Shatpushpadi Churna are found to be more effective than Simhanada Guggulu for all assessment criteria in the management of Amavata.

Conceptual Study of Shatpushpadi Lepa in Amavata

Amavata is most common disorder affecting the general population. Now a days, people have adopted unhealthy life style eating junk and doing vigorous exercise just after eating. In Ayurveda the causes of Amavata are Virudhha Ahara-Chesta, Mandagni, Nishchalata and doing Vyayama immediately after Snigdha Bhojana. The clinical presentation of Pravridhha Amavata closely resembles the Rheumatoid Arthritis. It is most common inflammatory arthritis and is major cause of disability. In Ayurveda various Deepana-Pachana, Aushadhis Sewana, Panchkarma therapies (Shushka Sweda, Virechana, Basti and Lepa) are mentioned in the treatment of Amavata. Shatpushpadi Lepa is one of the polyherbal compound mentioned by Acharaya Yogaratnakara in the management of Amavata. Almost all the ingredients of Shatpushpadi Lepa are having anti-inflammatory and analgesic properties. So, Lepa by its local application can combat the pathology in Rheumatoid Arthritis.

Management of Amavata with Panchakarma treatment – A case report

Abstract Rheumatoid Arthritis (RA) is an autoimmune systemic disease, resulting in functional decline, disability, and reduced quality of life particularly due to symptoms such as pain, fatigue, and morning stiffness. This manifestation is comparable to Amavata in Ayurveda. A 26-year-old female diagnosed with RA was treated with Ayurveda modalities including Valuka swedana (~sudation therapy using sand), Virechana (~therapeutic purgation), Basti (~therapeutic enema), and Samshamana snehapana (~type of internal oleation for palliative purpose). The patient was assessed both subjectively and objectively before and after completion of the treatment. Before treatment, the values of rheumatoid factor, C-reactive protein, and erythrocyte sedimentation rate were 358.4, 13.7, and 80, respectively, which were reduced to 153.1, 2.74, and 17, respectively, after one month of treatment. In addition, marked improvement in clinical signs and symptoms such as pain, stiffness, and swelling in joints was also observed. The present case report showcases the significant effect of Valuka swedana, Virechana, Yoga basti, and Snehapana in the management of Amavata.

Management of Amavata with Ayurveda

Amavata could be an illness in which vitiation of Vata Dosha & amassing of Ama in joints. In cutting edge science it is compare with Rheumatoid Joint pain which may be a auto-immune clutter. Within the display period Amavata is most common malady influencing a huge matured populace. Amavata is result of Agnidushti, Amotpatti & Sandhivikruti, since of those treatment which normalize Agni, metabolize Ama & controls Vata & keep up sound Sandhi & Sandhistha Shleshma will be best for this disorder. Rheumatoid arthritis (RA) is a symmetric polyarthritis that causes, unfavorable inflammation and deformity associated with systemic involvement. The prevalence of rheumatoid arthritis in India among those mentioned is between 0.5-3.8% in women and 0.15-1.35% in men. In various studies, the treatment helps to relieve the symptoms, but the underlined pathology remains untreated because the treatment is ineffective and also causes many side effects & toxic symptoms. Amavata management concept has Dravya, Katu-Rasa, Dipan Pachana with Langhana, Swedana and Tikta as Shaman Chikitsa. As the first concrete description of Amavata as a disease can be found in Madhav Nidana, this study provides a systematic evaluation of Amavata w.s.r. Rheumatoid arthritis in all the classics of Ayurveda. Amavata is one of the incurable conditions due to its chronic nature, intractable nature, complications of disease.

A comparative clinical study of Erandbeejadi Gutika and Pippalyadi Gana Kashaya with external application of modified Ruksha Pottali Sweda in the management of Amavata

Background: Amavata is a very challenging and burning problem in society. The clinical presentation of Amavata is closely related to the special variety of musculoskeletal disorder rheumatoid arthritis (RA). There is no medical system that is successful in providing a complete cure for the disease, so the Ayurvedic approach toward the treatment of Amavata is needed in the present era. The prevalence of RA is approximately 1% of the total population. For the management of RA in allopathic science, DMARDs & steroids are used frequently. Due to the lack of effective drugs and major problem in society, this disease for the study has been selected. Aim and Objectives: To study the efficacy of Erandbeejadi Gutika and Pippalyadi Gana Kashaya with modified Ruksha Sweda in the management of Amavata (RA). Methodology: It will be a single-center, randomized, open-clinical study. In this study, 60 clinically diagnosed patients of Amavata were selected and randomly divided into two groups by coin method. Erandbeejadi Gutika will be given in the dose of two tablets (each 500 mg) four times in a day with lukewarm water before meal for 90 days along with the modified Ruksha Pottali Sweda, while Pippalyadi Gana Kashaya will be given 50 ml two times in a day before the meal along with the modified Ruksha Pottali Sweda. Statistical analysis will be done using the Wilcoxon matched-pairs signed ranks test for the analysis of nonparametric data, while paired t-test will be used for parametric data analysis, and mann-whitney test and unpaired t-test will be used for intergroup comparison.

Efficacy of Pathyadi Churna and Trikatu Churna in the management of Amavata (rheumatoid arthritis)

BACKGROUND: Rheumatoid arthritis (RA) is a chronic, progressive, systemic autoimmune disease primarily affecting the synovial joints. Clinical symptoms of RA are similar to Amavata- a disease mentioned in Ayurveda. As per the Ayurveda classical texts, the formation and deposition of Ama (biotoxin) play a significant role in the pathogenesis of Amavata (RA). Hence, Deepana (appetite stimulant) & Ama-pachana (interventions that digest the biotoxins) can be first line of treatment for managing RA. Being Deepana and Pachana, Pathyadi Churna and Trikatu Churna can mitigate the Ama, prevent its genesis in the body, and thereby break down the pathogenesis of RA. Both formulations have anti-inflammatory and analgesic action which is supportive while treating RA. The present study will compare the efficacy of Pathyadi Churna and Trikatu Churna in managing RA. MATERIALS AND METHODS: It will be a randomized, parallel-group comparative trial with a sample size of 110 participants. Patients of any gender aged 18 to 65 years diagnosed with Rheumatoid arthritis based on American College of Rheumatology (ACR) 2010 criteria and presenting with Sama clinical features of Amavata will be enrolled in the study. Participants will be divided randomly into two groups. In group I, Pathyadi Churna, and Group II, Trikatu Churna will be administered in 3 gm and 1 gm, respectively, twice daily after food with lukewarm water for four weeks. The efficacy of the study interventions will be assessed through the changes in Disease Activity Score 28 (DAS28) and Ayurvedic disease-specific parameters from baseline. CONCLUSION: The study will help generate evidence regarding the efficacy of Pathyadi Churna and Trikatu Churna in managing RA.

Randomised Controlled Clinical Study of Shatyadi Kwatha in Amavata (Rheumatoid Arthritis)

The disease Amavata simulate with Rheumatoid Arthritis (RA) in modern parlanceis a symmetric, inflammatory, peripheral polyarthritis of unknown etiology with systemic involvement caused by the impairment of Agni (digestive fire), formation of Ama (bio-toxin) and vitiation of Vata Dosha. The disease Amavata (rheumatoid arthritis) still is a challenge to the physician due to its chronicity, incurability, complications, morbidity and crippling nature. A clinical study was conducted for 45 days at V.Y.D.S Ayurved Mahavidyalaya, Khurja, on 30 patients divided them into two groups of 15 each, to compare the efficacy of Shatyadi kwatha with the well-established control drug Maharasnadi Kwatha in the management of Amavata (rheumatoid arthritis). The demographic data of this study reveals that Amavata (rheumatoid arthritis) can begin at any age, but incidence increases with age. It clearly shows the predominance of the disease in females, in housewives, in addiction of tea/coffee and in Samashana group (consuming suitable and unsuitable foods mixed together). The clinical data of this study reveals that, both the drugs were found capable to enforce relief, but based on % of improvement and clinical assessment of result, it can be concluded that control drug (Maharasnadi Kwatha) was more effective than trial drug (Shatyadi kwatha) in most of the sign and symptom of the disease at extremely significant level.

Pharmaceutico-Analytical standardization of amavatari rasa – A herbo-mineral formulation

Introduction: Amavatari Rasa (AR) (mercury-containing herbo-mineral formulation), widely used in the management of Amavata (rheumatoid arthritis) has been being manufactured by many pharmaceutical companies in India for long. However, till today, the standard manufacturing process (SMP) for this formulation is not available, and hence, the present study was carried out to set the SMP of AR along with its quality control parameters. Methods: Pharmaceutical procedures such as Shodhana (pre-processing) of Parada (mercury), Gandhaka (sulfur), Chitraka (Plambago zeylanica Linn.), and Guggulu (Commiphora wightii Arn.); preparation of lime water, Triphla Kwatha (decoction) and AR were carried out at Rasa shastra and Bhaishajya Kalpana Department of ITRA, Jamnagar. Physicochemical parameters, high-performance thin-layer chromatography (HPTLC), and inductively coupled plasma atomic emission spectroscopy (ICP-AES) were carried out at the pharmaceutical chemistry Lab, ITRA, Jamnagar and Sophisticated Analytical Instrument Facility, IIT Powai, Mumbai respectively. Results: Average of 54.33 g of castor oil was required for 354.33g of AR. Mean ± standard deviation (SD) of pH, loss on drying, ash value, acid insoluble ash, water soluble extractive, and alcohol soluble extractive of AR was 3.77 ± 0.20, 6.29 ± 0.41%w/w, 5.46 ± 0.72%w/w, 0.40 ± 0.15%w/w, 23.2 ± 5.15%w/w and 30.13 ± 7.19%w/w, respectively. HPTLC study showed 4 peaks in 254 nm and 5 peaks in 366 nm ultraviolet lights. AR contains 7.38% mercury, 0.0031% arsenic, and 0.0032% lead. Conclusion: The adopted method for preparation of AR was convenient to replicate and hence can be considered SMP. Results of physicochemical parameters, HPTLC, and ICP-AES of this study could be used as quality parameters for Amavatari Rasa prepared by this method.

Management of Aamvata by Ayurvedic Treatment: A Case study

Amavata is a disease caused due to the vitiation or aggravation of Vayu associated with Ama. Vitiated Vayu circulates the Ama all over the body through Dhamanies, takes shelter in the Shleshma Sthana (Amashaya, Sandhi, etc.), producing symptoms such as stiffness, swelling, and tenderness in small and big joints, making a person lame. The symptoms of Amavata are identical to rheumatism, which include rheumatoid arthritis and rheumatic fever. It is observed that rheumatism is an autoimmune disorder, which is among the collagen disorders having strong and significant parlance with Amavata. Various drug trials were already carried out on Amavata, yet there is a lacuna in the management of Amavata. Rheumatoid arthritis (RA), an auto-immune inflammatory disease is one of the challenging conditions for the physicians to handle due to its chronicity, incurability, complications, morbidity, etc. In spite of potent anti-inflammatory agents and powerful immune-suppressive agents, its prognosis is not good, as these drugs have certain limitations including dependency and other side effects restricting quality of life. Considering these inconveniences, alternatives are being searched from traditional systems. Ayurveda through its armamentarium can provide leads in the management of this condition that is similar to Amavata in its clinical presentation. A 42-year-old female with diagnosed history of RA was treated by Ayurvedic medicines then improvement was observed in the overall effect of therapy.

A comparative clinical trial to evaluate the efficacy of Rasnadi Churna Basti with Ardha Matrika Basti in the management of Amavata vis-à-vis Rheumatoid Arthritis

Background: Amavata is one among the pain predominant diseases. The disease Amavata has similarity with Rheumatoid arthritis in clinical presentation. In the present study an attempt was made to compare the efficacy of Rasnadi Churna Basti with Ardha Matrika Basti in the management of Amavata. Objective of the study: To compare the efficacy of Rasnadi Churna Basti with Ardha Matrika Basti in the management of Amavata vis-à-vis Rheumatoid Arthritis. Materials and Methods: A double arm open labeled clinical study with pre-post-test design was carried out at Government Ayurveda Medical College and Hospital, Mysuru. Data was collected as per the proforma prepared for the purpose of the study. Study was completed in 42 subjects with 21 subjects in both the groups. For Group A Rasnadi Churna Basti and for Group B Ardha Matrika Basti in Yoga Basti pattern for 8 consecutive days was administered. The data was analyzed using SPSS descriptive and inferential statistics. Results: The statistical values showed highly significant results in Sandhi Shoola, Sandhi Shotha, Sandhi Stabhdata, functional grading, ESR, and DAS parameters. In CRP parameter, result was statistically significant in Group-A and non significant in Group-B. Hb% parameter showed statistically non-significant results in both the groups. On overall assessment, there was no statistically significant difference in the results between the groups except CRP and DAS parameters. Conclusion: Both Rasnadi Churna Basti and Ardha Matrika Basti are useful in reducing the signs and symptoms of Amavata vis-à-vis Rheumatoid Arthritis.

A randomised comparative clinical study to assess the efficacy of Lavangadi Churna over Ajamodadya Churna in the management of Amavata

Background - Amavata is a disease, where involvement of Ama and Vata can be seen. Here formation of Ama and vitiation of Vata take place simultaneously by their respective causative factors. Acharya Madhavakara has described the Amavata first. This Amavata can be compared with Rheumatoid arthritis showing similarities in clinical features. Objective - To assess the effect of Lavangadi churna over Ajamodadya Churna in the management of Amavata. Materials and Methods - The sample size of the study consists of 40 patients of Amavata. and either sex of age group 20-60years. Patients were randomly selected and grouped into 2 groups namely Group A & Group B. Group A were given Lavangadi churna and Group B were given Ajamodadya Churna. The dosage of both the drug is 3gms twice in a day after food with lukewarm water. Follow up was fixed every 15th day i.e., 1st follow up on 15th day, 2nd follow up on 30th day, after treatment follow up on 45th day and duration of treatment was fixed 1 month. Patients were advised to follow Pathyapathya throughout the study. A special proforma was made to record the observation based on subjective and objective parameters. Results and Conclusion - Overall effect of the trial drug showed good response in both subjective parameters & objective parameters and Overall effect of the control drug showed good response in some parameters like Heaviness, Anorexia, Thirst, Fever. Hence trial dug supported research hypothesis. Intervention was cost effective, adaptable, and safe.