Malignant Melanoma Of Female Urethra Research Articles

Primary Malignant Melanoma of the Female Urethra, A Rare Histologic Pathology Subtype and Poor Prognosis: Case Report

Introduction: Primary malignant melanoma of the genitourinary tract is extremely rare. The recommendations for management of this cancer still undefined due to paucity of literature. We report a case of primary malignant urethral melanoma developed in an elderly female patient. Presentation of case: 72 years old Thai female presented with palpable urethral mass with contact bleeding. On physical examination, there were no suspicious lesions on her skin. On external genital examination, a lesion at urethral meatus was observed and biopsied by rural doctor. The pathological diagnosis was malignant melanoma of urethra. Discussion: Despite major surgery, radiotherapy or immunotherapy malignant melanoma usually has a poor prognosis. We performed distal urethrectomy and followed up her clinical closely but unfortunately tumor recurrence in 15 months of the follow up. Conclusion: Primary malignant melanoma of female urethra is an extremely rare and poor prognosis. The histological and immunohistochemical findings can be helpful in making an accurate diagnosis.

Primary malignant melanoma of female urethra: a case report and review of literature

We report an extremely rare case report of primary malignant melanoma of female urethra. A 65 years old diabetic elderly postmenopausal female presented with a history of intermittent blood spots on undergarments for few days. Genital examination revealed a single, tan colored, soft chestnut size and polypoidal non ulcerated mass lesion protruding through the urethral meatus. Mass biopsy revealed poorly differentiated epithelial malignancy and immuno-histological analysis revealed positive with HMB 45 and protein S-100 suggestive of melanoma. Metastatic work up for the malignancy was negative. Complete urethrectomy with Mitrofanoff procedure with inguinal lymph node dissection was performed. Pathological diagnosis was malignant melanoma of urethra. We discuss the clinicopathological features and treatment option possible in this scenario.

S298: Primary malignant melanoma of female urethra: Case report

S298: Primary malignant melanoma of female urethra: Case report

Primary malignant melanoma of female urethra: A rare neoplasm

Primary malignant melanoma of urethra is an extremely rare entity. It has very poor prognosis. A 62-year-old post-menopausal female presented with complaints of voiding difficulty and a mass projecting from external urethral meatus. External genital examination revealed a growth arising from urethral meatus with blood-stained discharge from its surface. Biopsy from lesion confirmed the diagnosis to be malignant melanoma. Metastatic work up for the malignancy was negative. We describe the surgical management of this pathology at our tertiary care center and discuss the various treatment options possible in this scenario.

Primary malignant melanoma of female urethra: Savran, J., Sayer, E. A., and Schradiak, C. E.: Am. J. Surg., page 743, May, 1948

Primary malignant melanoma of female urethra: Savran, J., Sayer, E. A., and Schradiak, C. E.: Am. J. Surg., page 743, May, 1948

Primary malignant melanoma of female urethra

Primary malignant melanoma of female urethra