Main Research Hotspots Research Articles

Gold nanoparticles and breast cancer: A bibliometric analysis of the current state of research and future directions

Gold nanoparticles (GNPs) are widely searched for their usage in breast cancer research because of their unique features. For example, these particles can deliver drugs to specific sites, making imaging and photothermal therapy possible, thus rendering them suitable particles for theranostic purposes. Bibliometric research is a statistical analytical technique useful for the data systematically found in the literature. In this bibliometric study, the global research output regarding GNPs in breast cancer (BC) research was analyzed, mapped, and evaluated using bibliometric indicators.All documents related to the application of GNPs applications in BC research that were published in English-language, peer-reviewed journals over the past 20 years were retrieved from the Scopus database. Bibliometric indicators were extracted using VOSviewer and Biblioshiny. Thematic maps, conceptual maps, and visualization graphs were created.A total of 2035 published documents were retrieved. Chinese authors were the most active, having published approximately 27.5% of the total documents, while researchers from the United States (USA) had the most significant scientific impact. The study revealed weak international collaboration in this research area. Keywords mapping identified the main research themes and hotspots in this research field. Multimodal approaches in cancer treatment and diagnostics, targeted and effective cancer treatment, aptamers and biosensors, and green synthesis of GNPs were the four clusters retrieved from theme and hotspot analyses. This study analyzed and mapped the expanding field of GNPs in breast cancer research (GNP-BCR) and identified various applications of GNPs in this field. GNPs were used as drug delivery systems to target specific cancer cells and improve anticancer drug bioavailability. Different treatment and diagnostic modalities were revealed, such as photodynamic therapy (PDT) and photothermal therapy (PTT). Moreover, the development of aptamer-based biosensors using gold nanoparticles was identified as a niche theme in this research, while the green synthesis of GNPs emerged as a new and promising theme. However, clinical research is still warranted to translate this fundamental knowledge into practical and human-useable formulas.

Advances in the innovation of management: a bibliometric review

As the production model transforms from industrial manufacturing to a knowledge-based economy, management innovation becomes a strong driving force for economic growth and social development. This study examines academic findings on management innovation using the latest bibliometric methods and visualization tools based on papers published in top management journals in the Web of Science database from 2008 to 2022. (1) There are three main research hotspots. Through citation orientation, the research hotspots are business model innovation and environmental innovation; through outcome orientation, the research hotspot is knowledge innovation; and through intermediary orientation, the research hotspot is open innovation. (2) Regarding the distribution of major research institutions, seven institutions in the United States focus on innovation research and have a high impact. Six institutions in the United Kingdom focus on innovation research. Meanwhile, nine and three related institutions in Europe and Asia focus on innovation research, respectively. (3) Distribution of innovation articles in journals, Research Policy, Technovation, Journal of Product Innovation Management, and Industrial Marketing Management, contains the largest number of innovation research articles. Furthermore, this study examines new hot topics with time change and digital innovation. This paper provides the latest overview of innovation research in management and discusses the evolution and development of this field.

Visual analysis based on CiteSpace software: a bibliometric study of atrial myxoma.

To use CiteSpace and VOSviewer visual metrology to analyze the research status, frontier hotspots, and trends in research on atrial myxoma. The Web of Science core collection database was used to retrieve relevant literature on atrial myxoma from 2001 to 2022. CiteSpace software was used to analyze keywords with a co-occurrence network, co-polymerization class, and burst terms, and a corresponding visual atlas was drawn for analysis. A total of 893 valid articles were included. The country with the highest number of articles was the United States (n = 186). The organization with the highest number of articles was the Mayo Clinic (n = 15). The author with the highest number of articles was Yuan SM (n = 12). The highest cited author was Reynen K (n = 312). The highest cited journal was Annals of Thoracic Surgery (n = 1,067). The most frequently cited literature was published in the New England Journal of Medicine in 1995, which was cited 233 times. The keywords co-occurrence, copolymerization analysis, and Burst analysis revealed that the main research focuses were surgical methods, case reports, and genetic and molecular level studies on the pathogenesis of myxoma. This bibliometric analysis revealed that the main research topics and hotspots in atrial myxoma included surgical methods, case reports, genetic and molecular studies.

The Application of Blockchain in Supply Chain Management： Knowledge Mapping Analysis Based on Citespace

This study examines the present scholarly research on blockchain technology in supply chain management. The primary purpose of this working paper is to visualize and perform a scientometric review of 468 publications and research published between 2007 and 2021 from the Web of Science database. Co-author analysis, co-word analysis, and co-citation analysis highlight main concepts and research hotspots and provide light on important specializations and developing trends. This study primarily uses Citespace5.8. R1 to conduct a systematic analysis of author collaboration networks, keyword co-occurrence networks, keyword clustering, keyword burstiness, and literature co-citation graph spectrum networks in the domain of blockchain in supply chain management to identify the research state, development trend, hotspots, and frontiers. Research shows that :(1) since 2017, the literature on the application of blockchain in supply chain management has expanded rapidly. China and the United States are particularly advanced in this area compared to other nations. (2) The "blockchain in supply chain management" research mainly focuses on technical framework theory, which uses distributed ledger technology and smart contracts to control supply chain operations. Simultaneously, technical innovation should be combined with artificial intelligence, the Internet of Things, and other technologies to enhance the trust, transparency, traceability, performance index, and security of the supply chain. (3) The horizon of study in this area is the integration of RFID and blockchain technology for technical innovation in Industry 4.0, intending to improve and optimize each supply chain node.

Current status and prospects of diabetes mellitus induced erectile dysfunction: A bibliometric and visualization study.

The prevalence of diabetes mellitus-induced erectile dysfunction (DMED) has recently increased, which has prompted numerous DMED studies. Here, we conduct a bibliometric analysis of relevant literature in the field of DMED and to discuss the research hotspots and future development directions. The Web of Science Core Collection database was searched for literature on DMED, and literature characterization including the number of articles, journals, countries/regions, institutions, authors, keywords, and other information was performed using VOS viewer and CiteSpace software. In addition, Pajek software was used for visual map adjustment, and GraphPad Prism was used to generate line graphs. A total of 804 articles concerning DMED were included in this study. The Journal of Sexual Medicine issued the most documents(92 articles). The United States and China were in the leading position in the field of DMED research, and cross-institutional collaboration on DMED research worldwide needs to be further strengthened. Ryu JK were the authors with the highest number of documents issued (22 articles) while Bivalacqua TJ was the author with the most co-citated(249 co-citated). The keywords analysis shows that the main research hotspots in the field of DMED were mechanism discussions and disease treatment and management. Global research on DMED is expected to increase further. The investigation of the mechanism of DMED and the exploration of new therapeutic means and targets are the focus of future research.

A CiteSpace-based Overview of Hot Topics in Chinese Linguistics Research (2011-2021)

This paper retrieves the keywords of “linguistics and counts the relevant articles of Modern Foreign Languages in the past ten years from the database of China Knowledge Network (CNKI) and analyzes the keywords by using CiteSpace, a visualization software. Based on the visualization analysis, it can be found that linguistics research in China has basically formed a development trend of application-oriented research and interdisciplinary intersectional research in the past ten years, among which applied linguistics, systemic functional linguistics, foreign language teaching and cognitive linguistics are the main research hotspots in the field of linguistics in China in the past ten years.

A Scientometric Visualization of 32 Years of Leukemia Research in India

ABSTRACT A scientometric study examines the publication’s quantitative and qualitative trends in a particular research area. The present study investigates 2,854 leukemia research outputs of India published from 1989 to 2020, indexed in the Web of Science Core Collection database. Software, including bibliometrix Biblioshiny, BibExcel, HistCite and VOSviewer, have been used for data analysis. The Pediatric Blood & Cancer journal has the highest number of published articles. The USA collaborated with the highest number of publications with India. The All India Institute of Medical Sciences had the maximum number of publications. Bakshi S, Sharma A and Varma N were the leading authors of publications about leukemia research in India. Keyword analysis revealed that acute lymphoblastic leukemia, chronic myeloid leukemia, leukemia, acute myeloid leukemia and apoptosis were the main research hotspots in the area in all publications. The Department of Biotechnology (DBT), India and the National Institute of Health (NIH), USA, were the major funders in the leukemia research publications in India. The limitation of the study is that the data used is entirely dependent on the Web of Science (WoS) Core Collection database. So, the quality of the study is entirely dependent on the input information imported from the WoS database.

A bibliometric analysis of chronic obstructive pulmonary disease and COVID-19.

The coronavirus disease 2019 (COVID-19) outbreak became the worst epidemic in decades. Since its inception, COVID-19 has had a dramatic impact on chronic obstructive pulmonary disease (COPD) patients. This study explores explore the current status, hot spots, and research frontiers of COVID-19 and COPD based on a bibliometric approach. The Web of Science Core Collection was used to search the literature related to COPD and COVID-19, and VOSviewer and CiteSpace software were applied to analyze the distribution characteristics, research hotspots, and research frontiers of literature in related fields and to map the scientific knowledge domains. A total of 816 valid publications were included, among which USA, China, and England are the core countries/regions publishing related literature, and the research institutions are concentrated in Huazhong University of Science and Technology (18 papers), University College London (17 papers), and Imperial College London (16 papers). Guan WJ is the most prolific author with the most articles. The journals with the most publications are PLOS ONE, JOURNAL OF CLINICAL MEDICINE, and FRONTIERS IN MEDICINE. The main research hotspots in this field are clinical features, disease management, and mechanism research. By constructing COPD and COVID-19 research network diagrams, we reveal the hot spots, frontiers, and development trends of relevant research fields, which provide a reference for subsequent researchers to quickly grasp the current status of related research fields.

Research Hotspots and Trends of Eco-chemometrics in Lakeside Zone

In this study, the visualization tools CiteSpace and VOSviewer were used to visually analyze the research on ecostoichiometry in the lakeside zone, and the knowledge map of the research hotspots and trends of ecostoichiometry in the lakeside zone was drawn through the main research hotspots, research institutions and authors in the field. The method was to search the relevant journal literature collected in the past 20 years from CNKI and Web of Science databases, and finally retrieved the relevant literature that met the criteria, including 162 Chinese literature and 61 English literature. The retrieved English journals were mapped using VOSviewer software, while Chinese journals were mapped using CiteSpace. The visual results show that the number of publications in the field of ecological chemometrics in the lakeside zone at home and abroad shows a fluctuating upward trend. The most influential institution in China is Fujian Normal University, and abroad it is dominated by Qingdao University of Science & Technology. In the past 20 years, the research hotspots at home and abroad in this field have mainly been wetland restoration, nutrient storage, cultivated land protection, cultivated land ecological compensation and ecosystem service value. Research at home and abroad has roughly gone through two stages from the beginning to the rise of fluctuations. Through the literature analysis of influential authors, important research institutions, keywords and other fields of ecological stoichiometry in the lakeside zone, it can provide reference and reference for further research in this field.

Advances and hotspots of phosphorus form analysis of sediments based on different extraction methods using CiteSpace

Phosphorus (P) forms in sediments can be affected by various environmental factors, and P transformation in the water-sediment interface contributes to the eutrophication of water bodies. Therefore, a series of methods have been proposed to extract P forms in sediments. In order to explore the progress and research hotspots of P form analysis of sediments using different extraction methods, the core collection of Web of Science is taking as data source, and the CiteSpace knowledge map analysis tool is used to carry out visual analysis from the aspects of publication output, country analysis, publishing institution analysis, keyword analysis, literature co-citation analysis, burst terms analysis, and cluster analysis. The literature on the extraction methods for P form analysis of sediments was found to have boomed from 2013 to 2022, with higher contributions from China, France and United States. The cluster analysis of keywords and co-citation clarified the main research frontiers and hotspots. The bioavailability, migration and transformation mechanisms of P forms will become a new hotspot in this field in the future.

Global scientific trends in laparoscopy and gastric cancer in the 21st century: A bibliometric and visual mapping analysis.

To use visual mapping and bibliometrics to analyze and summarize the valuable information on laparoscopic surgery for gastric cancer (GC) obtained in the last 20 years, so as to determine the research hotspots and trends in this field. We screened all literature on laparoscopic surgery for GC in the Web of Science published from 2000 to 2022 and analyzed the research hotspots and trends in this field using VOSviewer. A total of 2796 reports from 61 countries and regions were selected. Japanese researchers published the most papers (n=946), followed by those from China (n=747) and South Korea (n=557). Papers from Japan also had the most citations (n=21,836). Surgical Endoscopy and Other Interventional Techniques published the most reports on laparoscopic surgery for GC (n=386) and also had the highest total number of citations (n=11,076), making this journal the most authoritative in this field. Among the institutions, researchers from Seoul National University in South Korea had the highest numbers of published papers and citations. The keywords of the articles could be divided into five categories: surgical methods for GC, short-term and long-term efficacy of laparoscopic surgery, guiding role of laparoscopy in the treatment of advanced GC, diagnosis and treatment of early gastric cancer (EGC), and lymph node dissection. Keywords such as "laparoscopic proximal gastrectomy", "surgical outcomes", and "esophagogastric junction" have emerged recently, and relevant studies on laparoscopic surgery for adenocarcinoma of esophagogastric junction(AEG)have gradually become a hot topic and trend. This study adopted bibliometric analysis to identify the current research hotspots and research trends in the field of laparoscopic surgery for GC. Five main research hotspots of laparoscopic surgery for GC were also identified. Laparoscopic surgery for AEG may become an important research focus in the future.

The economic impact of climate change: a bibliometric analysis of research hotspots and trends.

Climate change has been a widely concerned issue for decades. As the key policy target, the economic impact caused by climate change has received general attention from scholars and governments around the world. For the number of literatures is huge and the relationships among the literatures are not clear, we aim to clarify the research hotpots and the research trends of current literatures and provide inspiration for the development directions of future research in this paper. Using the bibliometric method, this paper characterizes the literatures on the economic impact of climate change based on the Web of Science (WoS) Core Collection. The results reveal that the USA occupies the leading position of the studies, which publishes most documents, and contains the most productive institutes and well-known scholars. From 2009, the number of documents published by a Chinese scholar started to increase rapidly, which makes China the second most productive country in recent years. The journals both belong to the WoS Categories of economics and environmental sciences and tend to publish more literatures than others. Adaptation, vulnerability, uncertainty, economic growth, climate policy, ecosystem service, energy consumption, renewable energy, food security, and land use are the representative keywords that have both high frequency and high centrality. Potential benefits, fat-tailed risk, social cost, international migration, and sustainable intensification are the top five main research hotspots. Based on the citation network of the top 50 documents with the highest local citation score, four research trends are sorted out: (i) the methodological innovation to monetized estimate the economic impact of climate change, (ii) the effect of current and future adaptive measures on agriculture, (iii) the interactional relationship between induced technological change and carbon tax, and (iv) the effect on labor market caused by climate change.

Au@Ag/ultrathin g-C3N4/graphene composite surface-enhanced Raman scattering film with stable, flexible and self-cleaning capability

Flexibility and self-cleaning are the main research hot-spots in the development of plasma substrates for practical applications in Surface-enhanced Raman scattering (SERS) at present. In this study, a flexible composite Au@Ag/ultrathin g-C3N4/Graphene (AUG) film based on PDMS film was reported and used as a highly sensitive SERS substrate for the detection of rhodamine 6G (R6G) molecules. The Au@Ag nanosphere array formed by self-assembly provided dense hot-spots, the ultrathin g-C3N4 enabled the composite to possess excellent photocatalytic ability, and the graphene enhanced SERS detection and photocatalytic performance while improving the stability of the composite film. The results showed that the AUG flexible composite film had a detection limit of 10−12 M for R6G molecules. After 10 photocatalytic cycles of testing, the composite film maintained 83 % of SERS activity. Benefiting from the graphene covering the surface, the composite films showed only a 5 % decrease in SERS detection performance after 30 days of storage in air. The facile fabrication process of AUG composite film enables it to be an outstanding candidate for the flexible, inexpensive, and stable wearable SERS sensing systems.

The development trends and research fronts in orbital angular momentum technology: A bibliometric analysis

Orbital angular momentum (OAM) technology, refers to Laguerre-Gaussian (LG) beams, twisted beams, vector/vortex beams, acoustic vortex beams and fractional vortex beams. It is an emerging and promising technology to improve the communication capacity, spectral efficiency, and anti-jamming capability due to its helical phase fronts and infinite orthogonal states. Although the OAM research began in the 1990s, the developing trends, current status, issues and characteristics through a systematic observation have not yet been performed. This paper presents a knowledge-based evolution of OAM research published in the Web of Science (WoS) from 2011 to 2021 using bibliometric analysis in Citepspace. The results demonstrate that the bandwidth, efficiency, gain, divergence, phase quantization, bulky and complex feeding structures, misalignment, distortion, interferences atmospheric turbulence and diffraction were the key issues found in the OAM technology. The main research hotspots and categories, influential authors, leading journals, best institutions of OAM show a strong bias in favor of their functions and technology developments. The research on OAM was mainly performed by the counties that have developed the 5G and now moving towards 6G communications like China, USA and South Korea. This study would serve as an inclusive guide on the future research trends and status especially for the OAM researchers.

Data-Driven Evolution Analysis and Trend Prediction of Hotspots in Global PPP Research

Over the past three decades, there have been many comprehensive studies related to public–private partnerships (PPP), but the analysis at the macro level still lacks comprehensiveness and interpretability. Through the application of bibliometric analysis, 2-mode network, and strategic coordinate analysis, we systematically analyzed the derivative characteristics of the literature data and the coupling characteristics of countries and keywords. Moreover, through the frequency and betweenness centrality, etc., this paper determines the evolution path of keywords and the evolution direction of theme words and realizes the prediction of theme words and keywords in the future. The results show that: (1) Through the three-stage biclustering analysis, we determined the hot theme words and hot keywords for each stage and focused the theme direction and main research content of the evolution, which led to great interpretability of the data analysis in the literature characteristics; (2) Through the distribution characteristics of time and space, the USA, China, the UK and other mainstream publishing countries and their main research hotspots were determined. Among them, developing countries have strong willingness in academic cooperation and great potential for academic development; (3) According to the derivative characteristics of the literature data, it is predicted that the future research hotspots are: the integration of business economy and sustainability, the integration of policy support and innovative technology application, and the urbanization promotion of developing countries. Based on the findings, this study makes concrete and targeted research methods and provides reference value and application value for the future research and analysis of PPP.

Co-Word Analysis of First-Authored Publications Written by Top Cited Scholars of Social Work

Purpose: Bibliometric analysis has been widely adopted to measure individual productivity and discipline development. This study aims to advance the application of this method in the social work discipline. Method: Using the knowledge mapping technique in CiteSpace 5.8.R3, this study performed a co-word analysis of 1,007 first-authored articles published from 2000 to 2022 by 60 scholars who are listed among the top 2% most-cited scholars on social work and are holding doctoral degrees in the same field. Results: The cluster analysis identified seven main research hotspots and burst detection results revealed four groups of research frontiers, including spiritual and cultural needs, children's wellbeing, social work practices and development, and social work research, with bullying and peer victimization, particularly among African-American adolescents and youth in Chicago's southside, continuing to attract much research interest. Discussion: This study examines how individual works contribute to the conceptual structure and scientific evolution of social work.

CiteSpace-based global science, technology, engineering, and mathematics education knowledge mapping analysis.

To better understand the latest developments in global science, technology, engineering, and mathematics (STEM) education research, this study collected STEM education research materials to sort out the development of STEM education as a whole, so as to get a clearer path and trend of STEM education development. This study conducted a visualization and quantitative analysis of the literature on STEM education research in Science Citation Index Extended (SCI-E) and Social Science Citation Index (SSCI) using the CiteSpace (5.8.R3) tool. First, the basic information of STEM education was analyzed in terms of annual publication volume, authors, countries, and research institutions. Secondly, the main fields, basic contents and research hotspots of this research were analyzed by keyword co-occurrence and keyword time zone mapping. Finally, the research frontiers and development trends are presented through co-citation clustering and high-frequency keyword bursts. The research hotspots are focused on engineering education, teachers' professional development, and gender differences. The research frontiers are mainly related to teacher professional development, 21st century skills, early childhood creativity, and gender differences. This study systematically analyzes the latest developments in global STEM education research, which is beneficial for readers to understand the full picture of STEM education research so that researchers can conduct more in-depth studies and promote better development of STEM education. The number of analyzed literature is limited. We only analyzed articles from SSCI and SCI-E databases, and the articles were written in English. In addition, we only analyzed the literature and lacked empirical studies on the findings of the literature.

Global research trends in penile cancer: Bibliometric and visualized analysis.

Penile cancer is a malignant tumor of the genitourinary system that mostly occurs in middle-aged and elderly men aged 50-70 years, which can seriously affect physical, psychological, and sexual health. Hundreds of original articles and reviews on penile cancer are published each year. However, a bibliometric analysis of these publications has not been performed. This study aimed to systematically analyze and visualize penile cancer-related publications through bibliometrics and reveal identified topics, hotspots, and knowledge gaps in related fields. Based on the Web of Science core collection database, we first analyzed the quantity and quality of publications in the field of penile cancer. Second, we profiled the publishing groups in terms of country, institution, author's publication, and cooperation network. Then, we systematized and summarized the hot topics of research. This bibliometric analysis was conducted from 2001 to 2022. The analysis identified 1,687 articles and reviews, which were published in 432 journals. The number of publications and citations on penile cancer-related research has steadily increased over the last two decades. Furthermore, academic institutions in Europe and the United States play a leading role in penile cancer research. The country, institution, journal, and author with the most publications were the United States (507), H Lee Moffitt Cancer Research Center (96), Journal of Urology (83), and Spiess P (87), respectively. The most frequently used keywords were penile cancer (743), squamous-cell carcinoma (717), cancer (380), carcinoma (232), lymphadenectomy (229). 16 keyword clustering information was obtained, including #0 male circumcision, #1 lichen sclerosus, #2 chemotherapy, #3 penile neoplasms, #4 targeted therapy, #5 resection margin, #6 cervical cancer, #7 lymph node dissection, #8 prognostic factor, #9 prostate cancer, #10 inguinal lymph node dissection, #11 human papillomavirus DNA, #12 gene, #13 penile intraepithelial neoplasia, #14 male sexual function, and #15 penile cancer. More and more scholars are devoted to the research on penile cancer. This bibliometric analysis revealed that the main research topics and hotspots in penile cancer included risk factors and surgical treatment plans.

Bibliometric Analysis of the Research (2000–2020) on Land-Use Carbon Emissions Based on CiteSpace

Carbon emissions are critical to climate change, and land-use change is an essential source of growth in carbon emissions. Research on land-use carbon emissions has become one of the hotspots in academic research. To explore the research hotspots and development trends of land-use carbon emissions in the last 20 years, CiteSpace software was used to conduct a quantitative analysis of relevant literature. This paper was based on the China National Knowledge Infrastructure (CNKI) and Web of Science (WoS) database literature on land-use carbon emissions from 2001 to 2020. The scientific research cooperation network CiteSpace software, with keyword co-occurrence, clustering, and burst word detection, was used to systematically analyze the main research strengths, hotspots and frontiers and clarify the research progress. The research results are as follows: (1) the amount of literature and the depth of research on land-use carbon emissions have increased yearly. However, there is little cooperation between research institutions and scholars, and there is still a lack of large-scale and stable research teams. (2) At the research hotspot level, the English literature focuses on building models and theoretical frameworks to study the internal mechanisms and driving factors of carbon emissions and climate change. The Chinese literature focuses on achieving regional carbon emissions reductions and carbon cycle goals and optimizing a low-carbon economy, transportation and land-use structure. (3) Research frontiers and trends show that the English literature first explored carbon sequestration, organic carbon, and carbon accounting. In China, the research frontiers are gradually becoming focused on influencing factors, decoupling analysis, and the built environment. The study will strengthen the intensity and depth of global carbon emission research and provide a reference for improving global climate change, protecting ecology and balancing economic development.

How much finance is in climate finance? A bibliometric review, critiques, and future research directions

This study describes and analyses the research hotspots and evolution trends in climate finance research. Seven literature clusters that elucidate how different perspectives constitute the research landscape in climate finance and two main research hotspots that form the climate finance domain are identified. The empirical results also show that the research priorities of climate finance are still less “finance-based”. In the future, finance scholars should pay more attention to the financial dimension of climate finance. Finally, the research gaps within the existing climate finance literature are identified, and 35 research questions for future research are proposed.