This letter reports an approach for growing semipolar (11–22) GaN films with significantly reduced defect densities on m-plane sapphire substrates by incorporating a sequence of two in situ SiNx layers. The first SiNx layer is deposited on an initial epitaxial GaN layer and acts as a nanomask for preventing the propagation of extended defects. The second SiNx layer is deposited just after subsequent epitaxial GaN overgrowth begins to form self-organized GaN islands, which encourages further GaN growth to initiate from the exposed island sidewalls while blocking the penetration of the remaining defects. X-ray rocking curve measurements show that our semipolar GaN films provide relatively low full width at half maximum values at 0.119° along both the [11–23] and [10–10] directions. Additionally, transmission electron microscopy analyses confirm that our semipolar GaN films provide a significantly reduced density of threading dislocations down to ∼6 × 108 cm−2, which is two orders of magnitude less than those of conventionally deposited films.