Low Expansion Research Articles

Enhanced interface bonding of hydrophobic encapsulated hydrogel fibers by mechanical interlocking structure: Toward anti-drying and anti-swelling strain sensors

Conductive hydrogel fibers with superior mechanical and electrical performance have been developed for flexible wearable electronics, but the inherent properties of hydrogels for dehydration in the atmosphere and underwater swelling limit its widespread application. In this work, a silicone rubber encapsulated hydrogel fiber with enhanced interface bonding, excellent mechanical and electrical properties was successfully developed, in which the core polyvinyl alcohol/sodium alginate hydrogel fiber was prepared by a continuous wet-spinning and the following freeze-thawing. The interlocking dual-network structure and the improved ion transport by negatively charged sodium alginate gave the core hydrogel fiber excellent strength of 4.15 MPa, elongation-at-break of 1531 % and electrical conductivity of 17.01 S·m−1. After encapsulation using a silicone rubber, the composite hydrogel fiber showed a low expansion rate underwater for 7 days of 1.00 ± 0.21 % and low weight loss in the air over 36 h of 38.67 ± 0.38 %. And the interface bonding of the core hydrogel fiber and silicone layer was enhanced by the bridging effect of amphiphilic stearic acid. Therefore, the composite hydrogel fiber demonstrated a great potential as a strain sensor for underwater communication to ensure the safety of individuals in an underwater environment.

Enhanced molecular stability of ApxII antigen during secretion in Corynebacterium glutamicum by rational design

ApxII is a vaccine antigen used to protect against porcine contagious pleuropneumonia, which is a significant threat to the pig industry. Here, we aimed to improve the proteolytic degradation stability of ApxII during its secretion by establishing a complete screening process of stable variants through bioinformatics and site-directed mutagenesis. We employed a combination of semi-rational and rational design strategies to create 34 single-point variants of ApxII. Among them, R114E and T115D variants exhibited better stability without compromising antigen activity. Furthermore, we constructed a multi-site variant, R114E/T115D, which demonstrated the best stability, activity, and yield. Protein stability and molecular dynamic analysis indicated that the greater solubility and lower structural expansion coefficient might explain the increased stability of R114E/T115D. Additionally, site T115 was identified as a key point of truncated ApxII stability. The R114E/T115D variant, with its proven stability and intact antigenic activity, holds promising prospects for industrial-scale applications in the prevention of porcine contagious pleuropneumonia.

Hydrothermal synthesis of SnO2/MoO3-x/rGO ternary nanocomposites as a high-performance anode for lithium ion batteries

The theoretical specific capacity of tin dioxide (SnO2) as a lithium-ion batteries (LIBs) anode material is up to 1494 mAh·g−1, far exceeding that of graphite. However, the low conductivity, volume expansion, crushing failure and particles agglomeration during charge/discharge cycles limit its application in LIBs. In this work, the SnO2/MoO3-x/rGO composite material was synthesized by one-step hydrothermal method, with SnO2 and amorphous MoO3-x tightly and uniformly anchored at the surface of reduced graphene oxide (rGO). The results of structural characterization and electrochemical performance evaluation show that amorphous MoO3-x can increase the reactive active sites, inhibit Sn particles aggregation, and promote the reversible reaction of SnO2. rGO effectively improves the electrical conductivity of the composite and buffers the volume change of Li-Sn alloying/dealloying during cycles. In addition, due to introduction of MoO3-x and rGO a stable SEI film can be formed at the material's surface to improve the cycle stability. SnO2/MoO3-x/rGO exhibits excellent rate performance and cycle performance. When the rGO content is 10.9 wt%, the reversible capacity of the composite reach 813 mAh·g−1 after 800 cycles at current density of 1.0 A·g−1, and 450.6 mAh·g−1 after 1000 cycles at current density of 5.0 A·g−1, with the capacity retention rate of 96.9%.

Expansions for semiclassical conformal blocks

We propose a relation the expansions of regular and irregular semiclassical conformal blocks at different branch points making use of the connection between the accessory parameters of the BPZ decoupling equations to the logarithm derivative of isomonodromic tau functions. We give support for these relations by considering two eigenvalue problems for the confluent Heun equations obtained from the linearized perturbation theory of black holes. We first derive the large frequency expansion of the spheroidal equations, and then compare numerically the excited quasi-normal mode spectrum for the Schwarzschild case obtained from the large frequency expansion to the one obtained from the low frequency expansion and with the literature, indicating that the relations hold generically in the complex modulus plane.

Noncovalent Interactions and Transverse Vibration Induced Restricted Thermal Expansion of Organic Salts Derived from Imidazole and Carboxylic Acids.

Design of material showing contraction upon heating is highly challenging due to varying mechanism. However, imidazole is found to be a potential molecule that may provide low CTE materials when incorporated in the matrix. Here we have reported thermal expansion property of imidazolium salts of five aliphatic α, ω-alkane dicarboxylic acids and three aromatic acids. Either uniaxial or biaxial negative thermal expansion (NTE) has been observed in most of the salts. In some cases, axial zero thermal expansion (ZTE) has been observed. The role of imidazolium moiety for the anomalous thermal expansion behaviour of the salts has been analyzed in this study. The controlled TE behaviour of the salts is attributed to the hydrogen bonding and transverse vibration in all imidazolium salts. Owing to the high transverse vibration observed in imidazolium ion as well as the heavier oxygen atoms of acids in each case, the distance between hydrogen bonded atoms decreases-which provides either low expansion or contraction along one of the principal axes.

Preparation of low thermal expansion, transparent LAS glass-ceramics via simplified heat-treatment method

Li2O–Al2O3–SiO2 (LAS) glass-ceramics are commercially significant due to their unique microstructure and exceptional properties, including near-zero thermal expansion coefficient, making them suitable for a wide range of applications. However, the content of SiO2 and Al2O3 in the composition of LAS glass is very high, which leads to high viscosity and very difficult melting of this type of glasses. In order to reduce the melting temperature of the glass, use of relatively high Na2O in the basic glass composition allows high-quality glass to melt. Employing a simplified heat-treatment method, LAS glass-ceramics are prepared with Australian spodumene as the primary material. By exploring the effect of crystallization temperature on the structures and properties of the resulting LAS glass-ceramics, samples with excellent comprehensive properties are achieved. The prepared glass-ceramics are thoroughly characterized using DSC, XRD, FTIR, SEM, and TEM, along with assessments of their viscosity, thermal, optical, and mechanical properties. Relatively more Na2O is introduced into the glass compositions, which can lower the melting temperature of the glass to below 1600 °C. The basic glass is annealed at 700 °C for 2 h, nucleation phenomenon Nucleation phenomenon can be generated in the LAS glasses. When the microcrystalline temperature of glasses increases from 835 °C to 910 °C, the main crystalline phase of glass-ceramics changes from β-quartz solid solution to β-spodumene solid solution. The change in the main crystal phase has significantly affected the properties of glass-ceramics. When the crystallization temperature is below 860 °C, the glass-ceramics exhibit a low negative expansion coefficient (<-0.5 × 10−6 K−1), high visible light transmittance (>85 %), and excellent average flexural strength (173.3 MPa).

Sequencing-Dependent Impact of Carbon Coating on Microstructure Evolution and Electrochemical Performance of Pre-lithiated SiO Anodes: Enhanced Efficiency and Stability via Pre-Coating Strategy.

Silicon monoxide (SiO) has attracted considerable interest as anode material for lithium-ion batteries (LIBs). However, their poor initial Coulombic efficiency (ICE) and conductivity limit large-scale applications. Prelithiation and carbon-coating are common and effective strategies in industry for enhancing the electrochemical performance of SiO. However, the involved heat-treatment processes inevitably lead to coarsening of active silicon phases, posing a significant challenge in industrial applications. Herein, the differences in microstructures and electrochemical performances between prelithiated SiO with a pre-coated carbon layer (SiO@C@PLi) and SiO subjected to carbon-coating after prelithiation (SiO@PLi@C) are investigated. A preliminary carbon layer on the surface of SiO before prelithiation is found that can suppress active Si phase coarsening effectively and regulate the post-prelithiation phase content. The strategic optimization of the sequence whereprelithiation and carbon-coating processes of SiO exert a critical influence on its regulation of microstructure and electrochemical performances. As a result, SiO@C@PLi exhibits a higher ICE of 88.0%, better cycling performance and lower electrode expansion than SiO@PLi@C. The pouch-type full-cell tests demonstrate that SiO@C@PLi/Graphite||NCM811 delivers a superior capacity retention of 91% after 500 cycles. This work provides invaluable insights into industrial productions of SiO anodes through optimizing the microstructure of SiO in prelithiation and carbon-coating processes.

Synergetic interface engineering and space-confined effect in CoSe2@Ti3C2Tx heterostructure for high power and long life sodium ion capacitors

The intriguing characteristics of two-dimensional (2D) heterostructures stem from their unique interfaces, which can improve ion storage capability and rate performance. However, there are still challenges in increasing the proportion of heterogeneous interfaces in materials and understanding the complex interaction mechanisms at these interfaces. Here, we have successfully synthesized confined CoSe2 within the interlayer space of Ti3C2Tx through a simple solvothermal method, resulting in the formation of a superlattice-like heterostructures of CoSe2@Ti3C2Tx. Both density functional theory (DFT) calculations and experimental results show that compared with CoSe2 and Ti3C2Tx, CoSe2@Ti3C2Tx can significantly improve adsorption of Na+ ions, while maintaining low volume expansion and high Na+ ions migration rate. The heterostructure formed by MXene and CoSe2 is a Schottky heterostructure, and its interfacial charge transfer induces a built-in electric field that promotes rapid ion transport. When CoSe2@Ti3C2Tx was used as an anode material, it exhibits a high specific capacity of up to 600.1 mAh/g and an excellent rate performance of 206.3 mAh/g at 20 A/g. By utilizing CoSe2@Ti3C2Tx as the anode and activated carbon (AC) as the cathode, the sodium-ion capacitor of CoSe2@Ti3C2Tx//AC exhibits excellent energy and power density (125.0 Wh kg−1 and 22.5 kW kg−1 at 300.0 W kg−1 and 37.5 Wh kg−1, respectively), as well as a long service life (86.3 % capacity retention over 15,300 cycles at 5 A/g), demonstrating its potential for practical applications.

Theoretical prediction of high temperature mechanical, thermodynamic and surface O adsorption properties of W-Cu alloys: Advanced high temperature super strength alloy materials

This paper constructs four alloy structural models of W15Cu1, W14Cu2, W13Cu3 and W12Cu4 as research objects. Based on phonon spectra analysis, the structure of W12Cu4 is unstable. Thus, the mechanical and thermodynamic properties for pure W, W15Cu1, W14Cu2 and W13Cu3 are studied using first-principles methods. The results show that the bulk modulus of W-Cu alloys exhibits the characteristics of high-temperature strength alloys. In particular, the bulk modulus of W14Cu2 and W13Cu3 increases rapidly with temperature increasing; Meanwhile, The W-Cu alloys at high temperatures exhibit low expansion behavior. The coefficient of thermal expansion of W14Cu2 at 1290 K starts to be lower than that ofW, and decreases with temperature increasing. At 1370 K, the coefficient of thermal expansion of W13Cu3 begins to be lower than that of W14Cu2, which also decreases with temperature increasing. The W-Cu alloys at high temperatures exhibit excellent phonon thermal conductivity. The phonon thermal conductivity of W14Cu2 at 2230 K transcends pure W and then maintains a thermal conductivity of about 5.55Wm-1K−1. The phonon thermal conductivity of W13Cu3 at 2140 K begins to transcend W14Cu2, and also exceeds pure W at 2180 K, and increases rapidly with temperature increasing. At 0 K, the addition of Cu to W reduces the mechanical strength but increases the ductility.

Large-N integrated correlators in N\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{upgreek} \\setlength{\\oddsidemargin}{-69pt} \\begin{document}$$ \\mathcal{N} $$\\end{document} = 4 SYM: when resurgence meets modularity

Exact expressions for certain integrated correlators of four half-BPS operators in N\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{upgreek} \\setlength{\\oddsidemargin}{-69pt} \\begin{document}$$ \\mathcal{N} $$\\end{document} = 4 supersymmetric Yang-Mills theory with gauge group SU(N) have been recently obtained thanks to a beautiful interplay between supersymmetric localisation and modular invariance. The large-N expansion at fixed Yang-Mills coupling of such integrated correlators produces an asymptotic series of perturbative terms, holographically related to higher derivative interactions in the low energy expansion of the type IIB effective action, as well as exponentially suppressed corrections at large N, interpreted as contributions from coincident (p, q)-string world-sheet instantons. In this work we define a manifestly modular invariant Borel resummation of the perturbative large-N expansion of these integrated correlators, from which we extract the exact non-perturbative large-N sectors via resurgence analysis. Furthermore, we show that in the ’t Hooft limit such modular invariant non-perturbative completions reduce to known resurgent genus expansions. Finally, we clarify how the same non-perturbative data is encoded in the decomposition of the integrated correlators based on SL(2, ℤ) spectral theory.

Circular Economy of Construction and Demolition Waste for Nanocomposite Cement: XRD, NMR, Vickers, Voltammetric and EIS Characterization.

In this paper, we present the structural, mechanical and electrical properties of composite cement materials that can be widely used as substituent for cement. We start with the characterization of a composite cement sample using an analysis of X-ray diffraction (XRD) and nuclear magnetic resonance (NMR) spectra. The measurements of the Vickers hardness, cyclic and sweep linear voltammetry and electrochemical impedance spectroscopy (EIS) of composite cement materials were also recorded. This study compared the effect of the different nanocomposites added to cement on the mitigation of the alkali-silica reaction, which is responsible for the swelling, cracking and deleterious behavior of the material. The enhancement in Vickers hardness was more pronounced for composite cement materials. In contrast, the values of Vickers hardness decreased for the composite cement containing mortar and the control sample, suggesting that the long-term performance of cement was compromised. In order to obtain information about the bulk resistance of the composite cement material, electrochemical impedance spectroscopy (EIS) data were employed. The results suggest that for composite cement materials, there is an improvement in bulk electrical resistance, which can be attributed to the lower amounts of cracks and swelling due to lower expansion. In the control sample, a reduction in the bulk resistance suggests the formation of microcracks, which cause the aging and degradation of the material. The intersection of arcs in the EIS spectrum of the mixed composite cement sample gradually increased by an alkaline exposure of up to 21 days and finally shifted towards a low value of high frequency with an increase in alkaline exposure of up to 28 days.

Experimental and theoretical investigation of silicon-based carbon composite electrode for high performance Li-ion capacitors

Lithium-ion capacitors (LICs) have garnered significant attention in recent years due to their ability to overcome the shortcomings of lithium-ion batteries (LIBs) and supercapacitors (SCs). Silicon (Si) stands out as a superior anode material for LICs due to its compelling attributes, including a high theoretical specific capacity (4200 mAh/g) and a low de-lithiation potential. Nevertheless, the inherent challenges of Si, such as low electrical conductivity and significant volume expansion (300 %), contribute to low electrochemical performance. To address this issue, a conductive carbon layer is introduced on Si using a simple and scalable approach. The resulting architecture, known as carbon-encapsulated Si (Si/C), not only improves electrical properties by enhancing Li+ diffusion but also mitigates volume expansion, leading to enhanced capacity and cyclic stability. Theoretical findings based on density functional theory (DFT) support these enhancements, confirming improved interactive properties at an atomic scale, including low binding energy and accelerated charge transfer kinetics (higher valence charge transfer) between the Si/C electrode and Li ions. As a result, the ‘binder-free’ and flexible Si/C electrode exhibits a notable initial discharge capacity (3450 mAh/g at 0.05 C) with improved rate capability (3010 mAh/g at 0.1 C). When employed as an anode in LICs, the Si/C electrode exhibits outstanding performance, boasting a large energy density (222.29 Wh/kg), high power density (25 kW/kg), and superior cyclic stability (81.3 % over 10,000 cycles). These findings highlight the potential of the Si/C electrode as a formidable candidate for advanced energy storage applications.

Extremal Higgs couplings

We critically assess to what extent it makes sense to bound the Wilson coefficients of dimension-six operators. In the context of Higgs physics, we establish that a closely related observable, cH, is well defined and satisfies a two-sided bound. cH is derived from the low momentum expansion of the scattering amplitude, or the derivative of the amplitude at the origin with respect to the Mandelstam variable s, expressed as M(HiHi→HjHj)=cHs+O(gSM,s−2) where gSM represents all Standard Model couplings. This observable is and, as a result, not sign-definite. We also determine the conditions under which the bound on cH is equivalent to a bound on the dimension-six operator OH=∂|H|2∂|H|2. Published by the American Physical Society 2024

Robust silicon/carbon composite anode materials with high tap density and excellent cycling performance for lithium-ion batteries

Achieving high density while ensuring structural stability and low volume expansion during cycling remains challenging for Si-based anode materials in lithium-ion batteries (LIBs). Herein, we introduce a novel approach to address this issue by developing high tap-density carbon-coated sub-nano-Si-embedded activated carbon (ACSC) anode materials. The resulting ACSC exhibits an ultra-high true density exceeding 0.99 g cm−3 and a Si content of 48 % (abbreviated as ACS0.48C), leading to an impressive volumetric capacity of 2182 mA h cm−3. Despite the high tap density and Si content of ACS0.48C, the ACS0.48C/artificial graphite (ACS0.48C/AG) mixture demonstrates a remarkable capacity retention rate of 97.9 % after 200 cycles at 0.5 C, with a modest volume expansion rate of 7.3 % after 50 cycles. The outstanding electrochemical performance can be attributed to the structural stability of ACS0.48C throughout cycling. The AC scaffold provides a robust mechanical framework to prevent volume expansion and agglomeration of sub-nano-sized Si particles. Furthermore, the homogeneous mixing of amorphous Si and carbon at the atomic level ensures isotropic expansion, thereby enhancing structural stability. The unique structure of ACS0.48C, combining high tap density and superior cycling performance, offers a solution to the low tap density issue in nanostructures and introduces innovative concepts for the morphology and structural design of Si/C secondary particles.

IoT Privacy Protection: JPEG-TPE With Lower File Size Expansion and Lossless Decryption

IoT Privacy Protection: JPEG-TPE With Lower File Size Expansion and Lossless Decryption

The aspherical explosions of the 03fg-like Type Ia supernovae 2021zny and 2022ilv revealed by polarimetry

Context. A peculiar subtype of Type Ia supernovae (SNe), 03fg-like (super-Chandrasekhar) SNe, show different observational properties from prototypical Type Ia SNe: they typically have high luminosities at the light-curve peak, low expansion velocities, and strong carbon features. The origin of this class of Type Ia SNe has been actively debated. Recent nebular-phase infrared observations of the 03fg-like Type Ia SN 2022pul using the James Webb Space Telescope revealed large-scale asymmetries in the ejecta and the presence of the strong [Ne II] line at 12.81 μm, suggesting a violent merger of two white dwarfs as its origin. Aims. Polarimetry is another powerful tool for studying the overall ejecta asymmetries of spatially unresolved SNe. Here, we aim to check the universality of the violent merger scenario as the origin of 03fg-like Type Ia SNe, by studying their explosion geometries using polarimetry. Methods. In this Letter we present imaging-polarimetric observations of the two 03fg-like Type Ia SNe 2021zny and 2022ilv. Results. SNe 2021zny and 2022ilv show high intrinsic polarization (∼1%–∼2%), which might be composed of multiple components with different polarization angles. This indicates that they have complex aspherical structures in their ejecta, supporting the violent merger scenario for their origin. Our observations provide the first clear evidence from polarimetry for such aspherical structures.

A Study on the Observation Status and Monitoring of Large Ocean Observation Buoys

More than half of the world's population is lives in coastal areas, and the effects of climate change are increasing. In particular, the prediction, forecasting, prevention and mitigation of disasters in coastal regions underscore the importance of real-time environmental information. This paper addresses the deployment and status of Large Ocean Observation Buoys installed by KIOST in the Yellow Sea/East China Sea in 2021. The buoys provide real-time time-series information not only for ocean physical and meteorological variables, but also for biogeochemical variables. In addition, the installed smart autonomous profiling system enables remote acquisition of vertical profiles of seawater. The data collected by the buoys will be visualized and displayed in real time on a web page. This study demonstrates the role of the buoys in monitoring ocean disasters and hazards using data collected during Typhoon Hinnamnor in 2022 and the low salinity water expansion of the Yangtze River. The use of the buoys for ocean monitoring is expected to be an effective means of responding to dynamic and abrupt environmental changes in the field, thus supporting rapid and effective responses to ocean disasters and hazards.

Optimization of Extrusion Parameters and Feed Composition for Enhanced Quality of Millet Extrudates

Extrudates prepared from cereal grains, such as corn, wheat, rice, and other starch-rich grains, are the second largest contributors to the global ready-to-eat snack market. These cereals contain optimal characteristics, like amount, type and particle size of starch/protein which are important for starch gelatinisation, viscosity and flow characteristics. These factors contribute to the rheology and organoleptic characteristics of the extrudates. In recent years, there has been a significant push in the utilization of the millets for development of extrusion products as they are ready-to-eat and considered as healthier. Major issues with 100% millet incorporation are dark colour, lower expansion, harder and denser extrudates and lower shelf life. In case of millets feed moisture (9-12%), barrel temperature (120-150°C) and screw (123-460 rpm) speed have favorable impact on expansion ratio and bulk density. Addition of starch containing cereals, legumes and hydrocolloids like sodium alginate and carboxymethylcellulose enhances expansion, lighten color and increases nutritional and health benefits. The aim of this review is to highlight the potential of extrusion technology for development of millet products, role of extrusion operating conditions and their effect on product parameters. The review also provides detailed insights about application of extrusion based 3-D printing, hot melt extrusion, hydrogel forming extrusion, centrifugal co-extrusion and extrusion-based encapsulation for the development of innovative millet based novel product development.

Physicochemical, functional, pasting, and amino acid compositions of milled rice, and extrusion behavior of milled rice from basmati and nonbasmati varieties

AbstractBackground and ObjectivesThis study was carried out to evaluate the difference in physiochemical, functional, cooking, textural, and pasting properties along with amino acid profile of nine basmati and nine nonbasmati rice varieties. Principle component statistical analysis was done to analyse the relationships among different properties of these varieties. Some verities containing high amylose content and good amino acid profile were selected for further development of extruded products (rice extrudates).FindingsVariations were observed in the physicochemical and functional properties of basmati and nonbasmati varieties. Low amylose rice varieties had higher cooking time, firmness, pasting temperature, and lower pasting viscosity. Selected high amylose‐containing varieties were showed higher bulk density but lower expansion ratio and hardness of rice extrudates. Result of this study will help industry for selection of rice for development of gluten‐free rice‐based breakfast cereals, puffed rice snacks, and so forth.ConclusionsAmong all varieties, PR122, PR128, PB3, PB4, and PB1121 exhibited higher levels of ash content, amylose content and protein content. Consequently, these varieties demonstrated longer CT, greater GSL, higher cooked grain firmness, and higher pasting PT, although they exhibited lower PV. PB1637, PB1509, PB1121, and PB4 displayed higher levels of essential AAs and sweet taste attributing amino acids, such as serine, glycine, and alanine, when compared to the other varieties. The results showed that rice containing higher amylose had lower expansion ratio of the extrudates, while higher bulk density and hardness. PR126 and CSR30 had the highest expansion ratio among the varieties that have been evaluated. Based on these results, PR126 and CSR30 could be used to make gluten‐free rice‐based breakfast cereals, rice snacks, and instant products.Significance and NoveltyPhysiochemical, functional, cooking, texture, pasting properties as well as amino acid profile were evaluated of different basmati and non‐basmati Indian (Punjab) varieties. Principle component (Relationship) analysis between various properties and different rice varieties was carried out. Extrusion is the most versatile processing technology used in the food industry to develop the product having better functional and sensory characteristics. The findings highlight the necessity of taking amylose content and amino acid composition into account when selecting rice types for preparation of extruded rice food.

MB2033, an anti-PD-L1 × IL-2 variant fusion protein, demonstrates robust anti-tumor efficacy with minimal peripheral toxicity

Interleukin-2 (IL-2), a cytokine with pleiotropic immune effects, was the first approved cancer immunotherapy agent. However, IL-2 is associated with systemic toxicity due to binding with its ligand IL-2Rα, such as vascular leakage syndrome, limiting its clinical applications. Despite efforts to extend the half-life of IL-2 and abolish IL-2Rα interactions, the risk of toxicity remains unresolved. In this study, we developed the bispecific fusion protein MB2033, comprising a novel IL-2 variant (IL-2v) connected to anti-programmed death ligand 1 (PD-L1) via a silenced Fc domain. The IL-2v of MB2033 exhibits attenuated affinity for IL-2Rβγ without binding to IL-2Rα. The binding affinity of MB2033 for PD-L1 is greater than that for IL-2Rβγ, indicating its preferential targeting of PD-L1+ tumor cells to induce tumor-specific immune activation. Accordingly, MB2033 exhibited significantly reduced regulatory T cell activation, while inducing comparable CD8+ T cell activation to recombinant human IL-2 (rhIL-2). MB2033 induced lower immune cell expansion and reduced cytokine levels compared with rhIL-2 in human peripheral blood mononuclear cells, indicating a decreased risk of peripheral toxicity. MB2033 exhibited superior anti-tumor efficacy, including tumor growth inhibition and complete responses, compared with avelumab monotherapy in an MC38 syngeneic mouse model. In normal mice, MB2033 was safer than non-α IL-2v and tolerable up to 30 mg/kg. These preclinical results provide evidence of the dual advantages of MB2033 with an enhanced safety and potent clinical efficacy for cancer treatment.