Losses In Brazil Research Articles

Genetic heterogeneity in autosomal recessive hearing loss: a survey of Brazilian families.

Hearing loss is a frequent sensory impairment type in humans, with about 50% of prelingual cases being attributed to genetic factors. Autosomal recessive hearing loss (ARHL) exhibits great locus heterogeneity and is responsible for 70%-80% of hereditary nonsyndromic cases. A total of 90 unrelated Brazilian individuals were selected for having hearing loss of presumably autosomal recessive inheritance, either born from consanguineous marriages or belonging to families with two or more affected individuals in the sibship and most cases were of normal hearing parents. In all cases, common pathogenic variants in GJB2 (c.35delG), GJB6 [del(GJB6-D13S1830) and del(GJB6-D13S1854)] and MT-RNR1 (m.1555A>G) were discarded and most were previously assessed by complete Sanger sequencing of GJB2. Their genetic material was analyzed through next-generation sequencing, targeting 99 hearing loss-related genes and/or whole exome sequencing. In 32 of the 90 probands (36,7%) causative variants were identified, with autosomal recessive inheritance confirmed in all, except for two cases due to dominant variants (SIX1 and P2RX2). Thirty-nine different causative variants were found in 24 different known hearing loss-associated genes, among which 10 variants are novel, indicating wide genetic heterogeneity in the sample, after exclusion of common pathogenic variants. Despite the genetic heterogeneity, some genes showed greater contribution: GJB2, CDH23, MYO15A, OTOF, and USH2A. The present results confirmed that next-generation sequencing is an effective tool for identifying causative variants in autosomal recessive hearing loss. To our knowledge, this is the first report of next-generation sequencing being applied to a large cohort of pedigrees with presumable autosomal recessive hearing loss in Brazil and South America.

Factors Related to Dizziness in Workers With Noise-Induced Hearing Loss in Brazil.

The purpose of this study was to describe the factors related to dizziness in workers with noise-induced hearing loss in Brazil. A cross-sectional study was carried out with a sample from noise-induced hearing loss reports (2007-2019). The dependent variable in this study was dizziness, and the independent variables were sociodemographic characteristics, comorbidities, symptoms, and noise characteristics in the work environment. Logistic regression analysis was performed. A total of 3,824 individuals with noise-induced hearing loss in Brazil were analyzed. The prevalence of dizziness was 23.4% in the sample. Factors associated with dizziness were women (odds ratio [OR]: 2.10; 95% confidence interval [CI] [1.64, 2.69]), hypertension (OR: 1.68; 95% CI [1.38, 2.06]), headache (OR: 6.31; 95% CI [5.26, 7.57]), tinnitus (OR: 3.46; 95% CI [2.82, 4.25]), and continuous noise at the work environment (OR: 1.54; 95% CI [1.22, 1.94]). The factors associated with the outcome-dizziness-were gender (female), systemic arterial hypertension, headache, tinnitus, and continuous exposure to workplace noise. Such findings demonstrate the importance of promoting a multifactorial approach to understanding dizziness among workers exposed to occupational noise.

Pollution-Related Biodiversity Loss in Brazil: More Actions Required

Pollution-Related Biodiversity Loss in Brazil: More Actions Required

The Impact of Land Conversion on Primate Habitats: Refining the Extent of Occurrence Data for Four Capuchin Species in North and Northeastern Brazil

AbstractConversion of primate forest habitat is a global concern with significant implications for primate populations. Although the geospatial Extent of Occurrence (EOO) data provided for primates by the International Union for the Conservation of Nature are widely used, they do not accurately reflect the existing extent of primate species because of ongoing habitat loss. We focused on four capuchin monkey species (Sapajus apella, S. flavius, S, libidinosus, and S. xanthosternos), all native to North and Northeastern Brazil, to prioritize research by the Capuchin Action Network. We refined the EOOs for the four primate species using MapBiomas land cover data. We accounted for areas of agriculture, urban, and mining and updated the EOOs of the four species. Additionally, we evaluated the Conservation Units in each EOO. Conservation Units are protected areas critical to mitigating habitat loss in Brazil. Our results show that S. apella has lost the smallest amount of its EOO (13%), while S. flavius has lost the most (77%). Agriculture was the leading cause of land cover change, followed by urbanization and mining. We provide an updated EOO for the four capuchin species and highlight the need for conservation efforts to address the challenges posed by human activities in the capuchin species’ habitats.

Validation and optimization of the loop-mediated isothermal amplification (LAMP) technique for rapid detection of wheat stripe mosaic virus, a wheat-infecting pathogen

BackgroundWheat stripe mosaic virus (WhSMV) is a significant wheat pathogen that causes substantial yield losses in Brazil and other countries. Although several detection methods are available, reliable and efficient tools for on-site WhSMV detection are currently lacking. In this study, a Loop-Mediated Isothermal Amplification (LAMP) method was developed for rapid and reliable field detection of WhSMV. We designed WhSMV-specific primers for the LAMP assay and optimized reaction conditions for increased sensitivity and specificity using infected plant samples. ResultsWe have developed a diagnostic method utilizing the Loop-Mediated Isothermal Amplification (LAMP) technique capable of rapidly and reliably detecting WhSMV. The LAMP assay has been optimized to enhance sensitivity, specificity, and cost-effectiveness. ConclusionThe LAMP assay described here represents a valuable tool for early WhSMV detection, serving to mitigate the adverse economic and social impacts of this viral pathogen. By enabling swift and accurate identification, this assay can significantly improve the sustainability of cereal production systems, safeguarding crop yields against the detrimental effects of WhSMV.

Efeitos da proteção solar e do manejo de água na fisiologia e produção de pomar de laranja ‘Pêra’ em clima subúmido

Abstract: The risks associated with climate events are the main factors responsible for sweet orange production losses in Brazil. For rainfed citrus cultivation, it is mainly due to soil water deficit, but also to citrus cultivation associated with extreme temperatures. The present study investigated the effects of water management in ‘Pera’ sweet orange orchards under sub-humid climate conditions and application of calcium carbonate-based sunscreen on the plant canopy, aiming to mitigate the effects of abiotic stresses on orchard physiology, production, and irrigation water use efficiency. The experimental design was in randomized blocks in a 3 x 2 factorial scheme. Treatments for water management factor were: full irrigation (100% ETc), irrigation with moderate deficit (65% ETc), and no irrigation; and for sunscreen protection: sunscreen use and no sunscreen. The factors have impacted gas exchange, fruit quality, and orchard yield. There was no isolated effect of soil water management on orchard productivity, but with sunscreen, citrus plants are more resilient based on gas exchange data, mitigating environmental effects (high temperatures and water deficit), resulting in improvements in fruit quality related to total fruit mass in plants grown without irrigation and with 12% increase in orchard productivity, regardless of soil water management. Productivity gains related to sunscreen indicate the need for the use of sunscreen protection regardless of soil water management in the region.

Tradução e validação do instrumento Childhood Hearing Loss Question Prompt List for Parents para a língua portuguesa brasileira

ABSTRACT Purpose This study aimed to translate and validate the Childhood Hearing Loss Question Prompt List (CHLQPL) for Parents into Brazilian Portuguese, supporting communication between healthcare professionals and families of children with hearing loss in Brazil. Methods A methodological approach was employed, comprising the translation and cross-cultural adaptation of the instrument, followed by validation through an iterative process involving experts and the target audience. The translation was conducted by bilingual translators, with subsequent back-translation and review by an expert committee to ensure conceptual and cultural equivalence. Validation involved collecting and analyzing feedback from parents of children with hearing loss and audiologists, using the Content Validity Index (CVI) to assess the instrument’s appropriateness. Results The analysis indicated positive acceptance of the translated instrument, with most items achieving a CVI above the threshold of 0.78, reflecting the instrument’s relevance and comprehensibility in the Brazilian context. One specific item did not reach the desired CVI, highlighting the need for further revision to optimize clarity and relevance. Conclusion The translated and validated CHLQPL proved to be an effective tool for the Brazilian context, facilitating family-centered communication and involvement in pediatric auditory care. This study reinforces the importance of adapting and validating assessment instruments to reflect cultural and linguistic specificities, ensuring applicability and effectiveness in assistingfamilies of children with hearing loss.

Evaluating the effect of temperature on Penaeus vannamei culture in a heterotrophic system and experimentally infected with the infectious myonecrosis virus

Causing economic losses in Brazil and Indonesia between 2002 and 2011 of over US$ 1 billion, infectious myonecrosis (IMN) constitutes a disease of mandatory notification to WHO (World Health Organization) and is responsible for constant damages in the production of the marine shrimp Penaeus vannamei. Although environmental factors such as high thermal amplitude, high concentration of nitrogen compounds and abrupt changes in salinity can alter the infection rate of this disease, there are still no studies. Thus, the present work aimed to evaluate the influence of temperature on the infectivity of IMNV in P. vannamei culture in a heterotrophic system. The experiment lasted 42 days, divided into two stages: (i) subjecting the shrimps to different temperatures (26 °C, 29 °C, 32 °C, and 35 °C) for 21 days; and (ii) viral challenge with IMNV via intramuscular injection (100 μL) also for 21 days, with evaluation of the shrimps by nested-PCR, histopathology and total and differential hemocyte count. The results obtained indicated that shrimps submitted to the highest temperatures evaluated (32 °C and 35 °C) had the highest post-viral challenge survival rates (85.42% and 93.75%, respectively), with less presence of lesions suggestive of IMN, although these shrimps were still positive by nested-PCR. No significant differences were observed in total hemocyte counts between pre- and post-challenge treatments (P > 0.05). In conclusion, the use of a temperature of 35 °C reduced mortality and viral load but altered the feed absorption, generating a reduction in zootechnical performance.

Assessing the impact of governance policies on landslide risk in Brazilian municipalities

Landslides triggered by heavy rainfall cause substantial losses in Brazil. This study investigates the impact of governance policies on landslide occurrences in Brazilian municipalities from 2000 to 2019, employing a Poisson pseudo-maximum likelihood estimator with high-dimensional fixed effects (PPML-HDFE). Panel regression analysis is conducted on environmental, socioeconomic, and policy factors influencing landslide frequency, clustering, and duration. A novel Landslide Risk Index (LRI), grounded in Intensity-Duration parameters, is introduced into the model as a nuanced risk assessment metric. Empirical findings reveal significant effects of specific policy interventions and substantial spatial variability in landslide risks. Precipitation patterns and municipal climate change laws are statistically significant in modulating landslide risks. While disaster warning systems have limited effectiveness, resilience initiatives like the UN Program for Resilient Cities substantially reduce landslide susceptibility in high-risk areas. The results advocate for context-specific policies tuned to local risk profiles rather than one-size-fits-all solutions. By bridging meteorological insights with policy-focused quantitative evaluation, the study makes a novel contribution to strengthening landslide resilience planning in Brazil.

Assessing land, nutrients and monetary value associated with postharvest loss of persimmon in Brazil: pathways toward sustainability in agri-food systems

PurposeThis study estimates the land footprint, nutrients and monetary value of persimmon loss in Brazil, and also consolidated the methodological approach for assessing resources related to food loss.Design/methodology/approachIt uses data on the harvested area, production, production loss and production value of persimmon in Brazil from 2014 to 2019. The persimmon loss in Brazil was converted into macro- and micronutrients, land use and monetary value.FindingsThe average annual production loss, loss production value and land footprint of persimmon are 35,100 tons, US$12m and 1,673 hectares, respectively. Persimmon loss represents the average loss per year of 6.6bn grams of carbohydrates, 1.6bn grams of food fibers, 7.2bn milligrams of vitamin C, 41.8bn micrograms of vitamin A, 4.5bn milligrams of calcium and 54.8bn milligrams of potassium. These nutrients have the potential to meet the nutritional daily needs of approximately 135,000, 176,000 people, 270,000, 164,000, 12,000 and 32m, respectively.Practical implicationsThrough (1) research and innovation; (2) infrastructure development; (3) training and education; (4) collaboration and networking; and (5) market diversification and value addition, people can increase persimmon shelf life, reduce postharvest losses and create a resilient environment for small persimmon farmers. This approach promotes sustainability in the agri-food system and empowers stakeholders.Originality/valueThis investigation helps to understand the value of food loss, considering the use of natural resources, as well as the loss of nutrients and monetary value.

First report of Lasiodiplodia brasiliensis causing crown rot on banana in Brazil.

Postharvest diseases compromise banana quality and cause high economic losses in Brazil. Among them, the crown rot prevails and its causal agents belong to distinct fungal species such as Colletotrichum musae (Berk. & Curt.) von Arx, Fusarium spp., and Lasiodiplodia theobromae (Pat.) Griff. & Maubl. (Griffee and Burden 1976; Ploetz et al. 2003). Symptoms of crown rot were observed on banana fruits of cv. Williams in a commercial area in Assu, Rio Grande do Norte, Brazil (04°54'0.06"S, 37°22'6.02"W) in 2017. The samples were collected, superficially disinfected with NaClO (2%), and incubated in a wet chamber at 25 °C, with a 12 h photoperiod, for approximately 3 days. After the appearance of disease symptoms and pathogen signs, mycelia were transferred from the lesions to obtain pure cultures on a potato dextrose agar (PDA) medium. Thus, a monosporic culture was obtained (isolate BAN82). The fungus produced pycnidia with conidia on potato carrot agar (PCA) culture medium containing pine needles, after four weeks of incubation at 28 °C. The conidia were hyaline when immature and brown with central transverse septum when mature. The presence of conidiogenous cells, paraphyses, and conidiophores also were observed. The conidia present ovoid format measuring 20-28 x 11-14 µm (n=50). The fungal colony produced abundant aerial mycelia of mouse grey coloration, progressing to dark mouse grey (Rayner 1970), on PDA for 15 days to 28 °C. The growth rate was 29.3 mm/day on PDA. The genomic DNA was extracted and amplified PCR with primers TEF1-688F/TEF1-1251R, ITS1/ITS4, and Bt2a/Bt2b and sequenced in both directions. The TEF1 and TUB2 sequences showed 100%, and the ITS showed 93.06% identity with the sequences of Lasiodiplodia brasiliensis (GenBank accession numbers: ON623895, TEF1, ON623896, TUB2, and ON599012, ITS. Multiple alignments of the combined dataset of the isolate and representative sequences obtained from GenBank were submitted phylogenetic analyses to bayesian inference (IB) with posterior probabilities of 10,000,000 generations. The morphological characteristics together with multigenic analysis of the three genomic regions made it possible to identify the BAN82 isolate as Lasiodiplodia brasiliensis, showing bootstrap support of posterior probabilities of 0,98 in the IB analysis. The pathogenicity was evaluated on 16 banana fruits from cv. Prata Catarina, at the point of harvest. For inoculation, the bananas were disinfected with water, soap, and, NaClO (2%). Posteriorly, the fruits were wounded on both ends, followed by the deposition of 5mm diameter mycelial plugs from the fungal culture, within 7 days of the growth. After the inoculation, the fruits were incubated in plastic boxes in a wet chamber at 25 °C, with 12 h photoperiod, for 3 days. To complete Koch's postulates, the isolate was inoculated again into 16 other banana fruits from cv. Prata Catarina. The negative control fruits were not inoculated with the pathogen, only with PDA discs. The BAN82 isolate was pathogenic to the banana cv. Prata Catarina. In the Brazilian Northeast, L. brasiliensis was described in 2014 as being associated with papaya stem rot. Up to the moment, there are no reports of L. brasiliensis as the causal agent of crown rot on bananas from Brazil (Netto et al. 2014; Farr and Rossman 2022). Thus, our work is the first to report L. brasiliensis causing crown rot on banana fruits cv. Prata Catarina in Brazil.

Trends in tropical forest loss and the social value of emission reductions

Reducing global forest losses is essential to mitigate climate change and its associated social costs. Multiple market and non-market factors can enhance or reduce forest loss. Here, to understand the role of non-market factors (for example, policies, climate anomalies or conflicts), we can compare observed trends to a reference (expected) scenario that excludes non-market factors. We define an expected scenario by simulating land-use decisions solely driven by market prices, productivities and presumably plausible decision-making. The land-use allocation model considers economic profits and uncertainties as incentives for forest conversion. We compare reference forest losses in Brazil, the Democratic Republic of Congo and Indonesia (2000–2019) with observed forest losses and assign differences from non-market factors. Our results suggest that non-market factors temporarily lead to lower-than-expected forest losses summing to 11.1 million hectares, but also to phases with higher-than-expected forest losses of 11.3 million hectares. Phases with lower-than-expected forest losses occurred earlier than those with higher-than-expected forest losses. The damages avoided by delaying emissions that would otherwise have occurred represent a social value of US$61.6 billion (as of the year 2000). This result shows the economic importance of forest conservation efforts in the tropics, even if reduced forest loss might be temporary and reverse over time.

EE21 COVID-19 Premature Mortality Productivity Losses: Real World Information Analysis

The aim of this analysis is to compare information regarding COVID-19 premature mortality productivity costs/ losses in Brazil. The states (S1 versus S2) in northern Brazil randomly chosen had criteria of similarity, tropical climate in most of the study period and population number. The study was carried out from March 2020 through November 2021 (20 months ). The reference of salaries to calculate possible losses due to deaths was obtained through accredited institutions, paylab, that study this specific information. Scenario A (Sc. A) = salary R$ 8.613,17 / month , scenario B (Sc. B) R$ 1.281,51 / month. Worker’s age range from 15 to 64 years. The regional gross domestic product (GDP) was not used due to biases. S1, 4,059 million inhabitants, 419,077 cases of confirmed COVID-19 , 8,948 deaths . In the following scenario, salary R$ 8,613.17 / month, (S1, Sc. A) the accumulated losses totaled R$ 1,541,412,903.20 (USD 280,256,891.49 at the rate 1 USD = 5,50 BRL), and (S1, Sc. B) totaled R$ 229,339,029.60 (USD 41,698,005.38). S2, 3,561 million inhabitants, 382,265 cases of confirmed COVID-19, 7,518 deaths . Considering the following scenario, salary R$ 8,613.17 / month, (S2, Sc. A) the accumulated losses totaled R$ 1,295,076,241.20 (USD 235,468,407.49 at the rate 1 USD = 5,50 BRL), and (S2, Sc. B) R$ 192,687,843.60 (USD 35,034,153.38). We estimate premature mortality productivity costs associated with COVID-19 across two states in northern Brazil are high and the conclusion is that the productivity losses based on regional GDP are difficult to detail. Further studies are needed to mitigate this situation.

Expectativa de vida com perda auditiva: estimativas para o Brasil

ABSTRACT Purpose to analyze the prevalence of self-reported hearing loss in relation to age, gender and regions of Brazil and to estimate life expectancy with hearing loss in Brazil, at birth and at age 60, for both sexes. Methods the Sullivan method was used, combining the life table and the prevalence of hearing loss in the period, as well as the adoption of data from the 2013 National Health Survey and Complete Life Tables, by sex, published by the Brazilian Institute of Geography and Statistics. Results in Brazil, in 2013, the prevalence of hearing loss gradually increased from the age of 60, in both genders, with males being more affected by hearing loss. Life expectancy at birth was 71.2 years for men and 78.5 years for women. Of these years of life, 3.4% (for men) and 2.8% (for women) were with hearing loss. At age 60, this difference remains, with an expectation of another 19.9 years for men and 21.7 years for women. In this age group, men had a rate of 2.2 years (11.3%) with hearing loss, while for women the rate was 2.1 years (9.7%). Conclusion in Brazil, based on data from 2013, there was a gradual increase in the prevalence of hearing loss from the age of 60 for both genders. Women had higher life expectancy, greater life expectancy free of hearing loss and live a smaller portion of their lives with hearing loss than men, regardless of age. The assessment of life expectancy with hearing loss at birth and at age 60 can help to understand the needs of the population, which allows for better planning of public policies related to the hearing health of individuals.

Sampling plan for socioeconomic development indicators in Brazil: practical implications when considering precision and cost

Socioeconomic development indicators such as Income, Human Development Index, and Gini Index have explained recent deforestation events in Brazil. These indicators, obtained from the demographic census, are expensive and are released every ten years. Despite being costly, they are important descriptors of the phenomenon of deforestation that occurs in one of the most relevant ecosystems in the world, the Brazilian forests. Therefore, the objective in this study was to detect the most representative and the lowest costly sample in order to obtain the referred indicators, from Brazilian municipalities from 2000 to 2010. The sample mean and confidence interval were obtained to be compared with the population average. The mean and confidence interval estimators come from 1,000 resamples according to simple random sampling and stratified random by geographic region. We evaluated the following sample intensities: 10%, 20%, 30%, 40% and 50% of the Brazilian municipalities. The results indicated that: a) 10% of Brazilian municipalities are sufficient to represent Income, HDI and Gini; b) We recommend both random and stratified sampling when selecting the municipalities that will provide the HDI and Gini values, on the contrary, for Income, the indicated sampling is the stratified one. These results show the importance of applied research in sampling and simulation to optimize the survey of demographic data collection, in a situation of budgetary constraint, in countries of vast dimensions such as Brazil. This study can increase understanding of the importance of socioeconomic development indicators to estimating progressive forest loss in Brazil, the country with the largest rainforest in the world.

Impacts of pests and diseases on the decline of managed bees in Brazil: a beekeeper perspective

Brazilian beekeepers have experienced massive colony losses in recent years. Possible causes include bee pests and diseases, although there have been few relevant studies in the country and no official data are available. The aim of this work was to assess, from a beekeeper's perspective, the incidence of pests and diseases in colonies, and their impact on the decline of bee populations in Brazil. The research used two online questionnaires that included disease symptoms to facilitate participant identification of diseases. A total of 674 valid responses were obtained from beekeepers of Apis mellifera (49% of the total) and stingless bees (51%), distributed among 24 of the 27 Brazilian states. Most beekeepers observed pests (average 78.1%) and disease symptoms (65.5%) in their colonies. Based on beekeepers' responses, pests and diseases affect beehive losses in Brazil. Colony loss percentage for A. mellifera was higher in apiaries with ants (19.8% of colony losses) and wasps (46.7%) than in those without pests (p < 0.001). While for stingless bees, meliponaries with robber bees (15.8% of colony losses), ants (14.7%), and phorid flies (12.5%) had higher colony losses than those without pests (p < 0.001). Apiaries and meliponaries with worker bee deaths had higher losses than those without symptoms. The results also indicate that monitoring can reduce colony losses in apiaries and meliponaries that have some kind of pests and diseases. Using a beekeeper perspective, this study provides information about the impact that pests and pathogens have on bee losses that can be used to guide improved management practices.

Non-technical Losses in Brazil: Overview, Challenges, and Directions for Identification and Mitigation

Non-technical losses directly affect the electricity distribution system's quality and create significant economic problems in developing countries. There has been an advance in Brazil's regulations to combat this kind of loss in the last 15 years. However, the electricity consumed and not billed is still high, impacting the electricity tariff and distributors' investment capacity and creating difficulties in developing public policies to mitigate the problem. Thus, this article seeks to present the panorama of non-technical losses in Brazil and propose legislative, regulatory, business, and academic directions. For this, 28 semi-structured interviews were carried out with specialists, resulting in identifying the main challenges for identifying and mitigating non-technical losses in Brazil and the factors that help overcome this problem. The results demonstrate that coordinated strategic actions among all stakeholders need to be developed to combat non-technical losses. The cultural change in acceptance of electricity theft needs to be one of the country's main focuses. The main contribution is to disseminate information to regulatory and legislative authorities, government, concessionaires, and researchers to develop practical actions for mitigating non-technical losses in Brazil.

Ocurrence enzootic hematuria in buffaloes in Brazil: epidemiological, clinical, and pathological aspects

ABSTRACT: It is reported the occurrence of enzootic hematuria (EH) in buffaloes in Brazil after performing an epidemiological survey and clinicopathological analises. To date, EH caused by ingestion of Pteridium esculentum subsp. arachnoideum, a radiomimetic plant popularly known as “bracken fern”, has not been described in this species in Brazil. Bovine EH is responsible for high economic losses in Brazil’s Southeast Region not only because of the deaths it causes, but also owing to its negative effect on productivity. In São José do Barreiro County, São Paulo, some farmers in areas with a high incidence of bovine EH have been replacing cattle with buffaloes, based on the premise that the latter would be more resistant to poisoning by ingestion of Pteridium spp. However, even though initial observations indicated that buffaloes are indeed less sensitive than cattle to the toxic principle of Pteridium spp., cases of hematuria in this species have been reported. According to preliminary date, EH only occurs in buffaloes over six years of age. Macroscopic examination revealed a thickened urinary vesicle mucosa, along with multiple foci of ulcerated, exophytic, verrucous, and pedunculated lesions. In one of the buffaloes studied, the bladder wall was ruptured and exhibited marked secondary inflammation. Histologically, neoplastic and non-neoplastic changes similar to those described in cattle poisoned by Pteridium spp. were observed. The neoplasms found included papilloma, carcinoma in situ, urothelial carcinoma (low and high grade), inverted, microcystic, and trabecular variants, urothelial carcinoma with divergent differentiation (squamous and glandular), squamous cell carcinoma, lymphangioma, hemangioma, and hemangiosarcoma. There was also coexistence of epithelial and mesenchymal neoplasms. Bovine papillomavirus particles were not detected by polymerase chain reaction in the bladder samples analyzed.

Critérios para a classificação do grau da perda auditiva e proteção social de pessoas com essa deficiência

ABSTRACT Purpose: to identify criteria used nationally and internationally to classify degrees of hearing loss, compare them with what is established in the Brazilian law, and discuss possible consequences of such a law on the social protection of people with hearing loss. Methods: a narrative review was conducted to identify the criteria used in this classification, by searching the platforms VHL and PubMed in April 2020. It included primary human research explicitly mentioning the criteria used to classify the degree of hearing loss, published between 2015 and 2019 in English, Spanish, and Portuguese. Literature Review: there is a preference for the four-frequency mean at 0.5, 1, 2, and 4 kHz. The Brazilian law does not follow these criteria, which may pose a barrier to people with hearing loss, hindering their access to social protection programs. Final Considerations: there is no consensus on the best criteria, although the most encompassing ones in hearing assessment predominate - which are not the ones legally used in Brazil. It is necessary to debate the Brazilian legal criteria to ensure existing social rights to part of people with hearing loss in Brazil.

Perda auditiva induzida por ruído no Brasil: descrição de 14 anos de notificação

ABSTRACT Purpose To describe the notifications of NIHL in Brazil, according to sociodemographic and labor aspects, in the period from 2006 to 2019. Methods Cross-sectional and descriptive study carried out with data from notification forms for noise-induced hearing loss in Brazil, from SINAN. The data were accessed through the page of the Collaborating Center for Surveillance of Workers’ Health Disorders (ISC-UFBA). Absolute and relative frequencies of sociodemographic variables and work characteristics were analyzed. Results During the period, 7,819 cases of NIHL were reported in Brazil. The year 2016 and the state of São Paulo registered the highest number of notifications, with 1,106 and 2,488 cases, respectively. Throughout the period, there was a higher proportion of cases in: individuals with a formal contract (55.0%), male (88.2%), white (59.1%) and aged between 50 and 59 years (33.7%). Continuous noise was predominant in the work environment (41.1%) and 51.1% of the individuals used individual protection measures, while 12.6% were protected collectively. Conclusion A total of 7,819 cases of NIHL were reported in Brazil in the period analyzed, a number that can be considered disproportionate in relation to the prevalence of this condition. The observed underreporting impacts on the understanding of the magnitude of the problem, and, consequently, on the development and implementation of public health actions and programs, aimed at worker health and safety.