The safety of Unmanned Surface Vehicle during the autonomous phase of navigation relies heavily on the onboard navigation equipment. However, in the face of changing and diverse navigation environments, global satellite navigation systems utilizing radio communication often face signal occlusions. This significantly reduces the positioning accuracy of navigation systems. To ensure the navigation accuracy of vehicles in various harsh environments, a Global Navigation Satellite Systems and Inertial Navigation System (GNSS/INS) integrated navigation system structure based on cascaded vector-tracking loop is proposed in this paper. The integrated navigation scheme not only improved the positioning accuracy of the navigation system but also effectively improved the robustness of the system. Compared with the traditional scalar-tracking loop and vector-tracking loop methods, it exhibits better performance. The experimental results show that the proposed method can reduce the horizontal position positioning error by 73.7% compared with the traditional vector-tracking loop method in the case of signal occlusion. Simultaneously, it can continuously output reliable and high-precision positioning information in the case of serious signal occlusion. The integrated navigation scheme proposed in this paper can be used as a research direction for the development of Unmanned Surface Vehicle navigation applications and provides solutions for the development of related navigation systems.