Limited research has been conducted on the influences of fiber content on close-in blasting characteristics for ultrahigh-performance fiber-reinforced concrete (UHPFRC) beams. This paper aims to address this knowledge gap through experimental and mesoscale numerical methods. Experiments were conducted on ten UHPFRC beams built with varying steel fiber volumetric fractions subjected to close-in explosive conditions. Additionally, this study considered other parameters, such as the longitudinal reinforcement type and ratio. In the case of UHPFRC beams featuring normal-strength longitudinal reinforcement of diameters Φ12, Φ16, and Φ20, a reduction in maximum displacement by magnitudes of 19.6%, 19.5%, and 17.4% was observed, respectively, as the volumetric fractions of fiber increased from 1.0% to 2.5%. In addition, increasing the longitudinal reinforcement ratio and using high-strength steel longitudinal reinforcement both significantly reduced the deformation characteristics and increase the blasting resistances of UHPFRC beams. However, the effects on the local crushing and spalling damage were not significant. A mesoscale finite element model, which considers the impacts of fiber parameters on UHPFRC beam behaviors, was also established and well correlated with the test findings. Nevertheless, parametric analyses were further conducted to examine the impacts of the steel fiber content and length and the hybrid effects of various types of microfibers and steel fibers on the blasting performance of UHPFRC beams.