In this study, a numerical model of the cable cabin of a comprehensive pipe gallery was established to study the smoke flow diffusion behaviour of a comprehensive pipe gallery fire under a rectangular cross-section. The effects of fire source power (Q = 0.5, 1.0, 1.5, 2.0, 2.5, 3.0 MW) and fire source location (D = 10, 20, 40, 50, 60, 80, 100 m) on the smoke flow characteristics—such as smoke layer height and thickness, longitudinal airflow velocity, and ceiling temperature distribution—were analysed, and the corresponding prediction model was fitted. The results show the following: (1) The height of the smoke layer decreases with increasing fire power, and the predictive model of the smoke layer thickness obtained from the fitting is proportional to the smoke mass flow rate and inversely proportional to the aspect ratio of the pipe gallery. (2) Longitudinal air velocity prediction models of D < 50 m and D ≥ 50 m are fitted, and the average error between them and the numerical simulation values is 9.611%. (3) The temperature decay gradient of the smoke decreases gradually with increasing distance from the fire source, while there is a significant temperature difference between the two sides of the fire source. The average relative errors of the dimensionless temperature rise models fitted upstream and downstream of the fire source in the form of ΔTT0=AeBD−XH+C exponentials with respect to the numerical simulations were 11.688% and 7.296%, respectively. The results of the study can provide a reference for smoke flow and fire prevention and control in comprehensive pipe galleries.
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