Drought is one of the natural phenomena influencing many aspects of human activities like water scarcity, food production, agriculture, industry and ecological conditions of the environment. For decades, drought has caused huge financial losses in Europe and around the world. In the area of the Polish Carpathians, there are periods with a deficit of rainwater and increasing frequency of dry months especially in the cold half-year. However, only a limited number of studies exist about the spatial and temporal variability of meteorological drought and the main mechanisms determining its performance in Central Europe. The aim of this work is to perform the spatial and temporal analysis of drought, expressed as SPI, in a heterogenous area of the Polish Carpathian and the highland region in the East-Central part of Europe based on long-term precipitation data. Moreover, for the first time in this work drought characteristics assessed by means of the SPI were discussed considering the atmospheric circulation calendar. In this work monthly precipitation from 55 rainfall stations were analysed from 1961 to 2022. The 3-, 6-, 9-, and 12-month Standardized Precipitation Index (SPI) was used as indicators of meteorological drought. For the 3-month SPI, the main climatic mechanisms determining extreme droughts were defined based on the calendar of synoptic circulations. The Mann-Kendall test was used to detect the trend of extreme droughts. Statistically significant trends of SPI were observed on 52.7% of all analyzed stations and, in most cases, a positive trend was observed, indicating an increase in water resources in the Upper Vistula Basin. Statistically significant trends were more frequently observed in stations located in the western part of the analyzed region. Long-term droughts, represented by the 12-month SPI, occurred in all stations but not in all years. Short-term droughts (3-month SPI) were most frequent in the winter season, 6- and 9-month SPI in winter and spring, and 12-month SPI in winter and autumn. The spatial distribution of droughts was highly diverse. The most intensive drought occurred in 1984, with the 6-month SPI covering 98% of the analyzed region, and the 9- and 12-month SPI covering 90% of the entire region. Droughts exhibit a seasonal pattern, with a dominant 10-year periodicity for all analyzed variants of SPI. Additionally, Fourier analysis revealed a 2-year periodicity for the 3-, 6-, and 9-month SPI and a 31-year periodicity for the 12-month SPI. The results provide insights into the typical climatic conditions in Poland, with strong seasonality in precipitation. The study highlighted that short-term extreme droughts, represented by the 3-month SPI, are often caused by anticyclonic situations with high-pressure wedges Ka and Wa, as observed in 52.3% of cases. These findings are crucial for understanding the spatial and temporal variability of short and long-term extreme droughts in Central Europe, particularly for the agriculture sector which is dominant in the northern part of the analyzed region, where drought frequency is highest.