This paper presents the first palaeodemographic results of a newly assembled region-wide radiocarbon record of the Arctic regions of northern Norway. The dataset contains a comprehensive collection of radiocarbon dates in the area (N = 1205) and spans the 10,000-year period of hunter-gatherer settlement history from 11500 to 1500 cal BP. Utilizing local, high-resolution palaeoclimate data, the paper performs multi-proxy correlation testing of climate and demographic dynamics, looking for hunter-gatherer responses to climate variability. The paper compares both long-term climate trends and short-term disruptive climate events with the demographic development in the region. The results demonstrate marked demographic fluctuations throughout the period, characterized by a general increase, punctuated by three significant boom and bust-cycles centred on 6000, 3800 and 2200 cal BP, interpreted as instances of climate forcing of human demographic responses. The results strongly suggest the North Cape Current as a primary driver in the local environment and supports the patterns of covariance between coastal climate proxies and the palaeodemographic model. A mechanism of climate forcing mediation through marine trophic webs is proposed as a tentative explanation of the observed demographic fluxes, and a comparison with inter-regional results demonstrate remarkable similarity in demographic trends across mid-Holocene north and west Europe. The results of the north Norwegian radiocarbon record are thus consistent with independent, international efforts, corroborating the existing pan-European results and help further substantiate super-regional climate variability as the primary driver of population dynamics regardless of economic adaptation.