Logical localism is a thesis within philosophy of logic according to which the correct logic is dependent on the topic, domain or subject matter of its application. There is a very straightforward problem for anyone defending a localist thesis, a problem that follows from the fact that we reason across domains. This challenge is known as the problem of mixed inferences. The problem is, very roughly, the following: suppose that there are at least two components, within the premises or conclusion of an argument, belonging to domains governed by different logics. Then, which is the criterion of validity for the mixed argument? Our aim is to offer an answer to this question and, more concretely, a way out to the dilemma that Chase Wrenn has raised in his analysis of the problem of mixed inferences. We will use Joshua Schechter’s method of combining logics, juxtaposition, as the criterion of validity for mixed inferences. After exploring its virtues and possible shortcomings, we argue that juxtaposition is a first step towards a fully-fledged solution, but already a promising way out of the dilemma posed by Wrenn.