Wind effects on a square model and a 90° helical model are investigated by both pressure measurement and aero-elastic model tests in a boundary layer wind tunnel. Based on the pressure measurement results, local wind force coefficients, base moment coefficients, vertical correlation coefficients and power spectral densities for the two models were analyzed and discussed in detail. The aerodynamic damping ratios were calculated by the random decrement technique (RDT) on the basis of the wind-induced acceleration obtained from the aero-elastic tests. Comparisons of wind loads and wind-induced accelerations were made for the square and helical models. The results shown that the aerodynamic damping should not be ignored, especially for across-wind direction. Moreover, the helical model has been proved to yield a better behavior in aerodynamic performance than square model. This study aims to provide useful information for wind-resistant design of helical building.