CONTEXTAgriculture-driven land conversion poses a significant threat to global biodiversity conservation. Balancing agricultural expansion with conservation is a critical challenge for governments and development partners. Sustainability-oriented agriculture programs such as conservation agriculture and land intensification aim to reduce land conversion and deforestation; however, evidence of their effectiveness remains complex and elusive, especially regarding the role of smallholders. OBJECTIVEThis study addresses this knowledge gap by systematically mapping the drivers of smallholder land conversion and their interconnections across three focal biodiverse contexts including sub-Saharan Africa, Latin America, and Southeast Asia as well as from a global scale. METHODSUsing literature that focuses on the nexus of smallholder farmers and agricultural intensification, this study systematically identified the potential of distinct factors and dynamic processes to serve as system leverage points toward improved outcomes for biodiversity, food security, and smallholder livelihoods, using a combination of structural factor analysis, centrality analysis, and feedback loop analysis. RESULTS AND CONCLUSIONSThe results highlight the importance of strengthening land tenure systems, providing technical support to farmers, improving market access, and prioritizing smallholder livelihoods in mitigating land conversion. SIGNIFICANCEContextual differences emphasize the need for context-specific interventions and further research to explore factors driving land conversion more deeply within specific contextual boundaries. Future studies should map proposed policy interventions onto local systems driving land conversion and incorporate the diverse perspectives of local stakeholders to guide effective and sustainable agriculture interventions.