Purpose. The purpose of the research is to study the ecological zoning of natural landscapes of the northeastern slope of the Lesser Caucasus. Method. During the writing of the article, historical, cartographic, mathematical-statistical, comparative analysis methods were used. The northeastern slope of the Lesser Caucasus was chosen as the research object Result. In the article, as a result of the research conducted for the ecological zoning of the natural landscapes of the North-Eastern slope of the Lesser Caucasus, the changes in the structural and functional characteristics of the natural landscape units of the area and the areas where they spread due to natural and anthropogenic influences were studied, landscape complexes were grouped according to the degree of anthropogenic transformation, new landscape types formed in the place of natural landscapes were investigated. At the same time, the main natural landscapes of the area, tugay forest-meadow-shrub landscapes, semi-desert landscapes, dry-desert landscapes, have changed their borders as a result of anthropogenic effects, and new areas where they spread have been studied. Opinions were discussed about the important role of determining a number of aspects of landscape-ecological zoning diagnostics, in revealing the future development trends of individual landscape units. Taking into account the relevance and modernity of the topic, a number of scientific-theoretical and methodological issues of landscape-ecological zoning for the region were analyzed in the area where the research was conducted. The basis of the work is that settlements and their functional farm areas are characterized by relatively high density in the immediate flat areas, terraced alluvial plains of river valleys, mountain depressions and smooth surface plains and the approximately equal distribution of settlements in the Ganja-Gazakh sloping plain throughout the territory, since the climate, lithological and hydrological conditions in the south-eastern part of the territory have changed sharply, the relatively low water supply in the location of settlements is a social and ecological problem, and therefore the location of settlements in the area along the river banks. Scientific novelity. Based on the ecological zoning of landscapes in the area, it is analyzed that the correct assessment of their ecological potential, the preparation of appropriate zones and belts, the assessment of geoecological potential by dividing into zones taking into account the ecogeographical potential of the natural landscapes of the region and anthropogenic loading, is of great scientific and theoretical importance.