In this proposed review article analyzes the literary and archive data that devoted to the study of floristic diversity within the territory of Podillya. Research in this region is historicall divided into four stages. From research directions of ecological and coenotic groups of different types of vegetation were allocated ecological, geobotanical, floristic, systematic, phytososological directions. It was determined, that the results of researches of such leading ecological and coenotic groups as forest, meadow, meadow-steppe, steppe, meadow-swamp and water-swamp vegetation were of great scientific importance and reflection of the specifics of species distribution within the region. We have determined, that descriptions of typical flora species appeared in the XIX century within the general characteristics of the region. It was established, that the first knowledge about the floristic diversity of the region was obtained with the activities of educational institutions, academies of sciences and the local lore scientific-research communities, one of their activities was thorough expeditionary research. During this period, were published the results of research of such authors as V. Besser, A. Andrzhievsky, V. Montresor, O. Rogovich, I. Schmalhausen. These works were of a general nature, but on the basis of the acquired knowledge and collected herbarium material, were formed consolidated lists of plant species, which gave a general idea of the specifics of the distribution of species in the region. Further research concerned the study of the genesis of flora, the definition of plant groups, species differentiation, habitats of individual and rare species, which became a prerequisite for floristic and geobotanical zoning. In this area, most famous studies were studies of J. Pachosky, M. Kotov, W. Szafer, Ye. Bradis, A. Barbarych, G. Kukovitsaetс. As a result of long-term expeditions and vegetation research, many well-known nature protection objects have been founded: Medobory Reserve, the national nature parks «Podilski Tovtry», «Karmeliukove Podillia», «Kremenets Mountains», «Dniester Canyon», «Lower Polissia», «Upper Pobuzhia», regional landscape parks «Maliovanka», «Zagrebellia», «Middle Pobuzhia», «Dniester», «Murafa», «Nemyrivske Pobuzhia» etc. At present, ansozological area of research is important and priority way in context of conservation and protection of phytodiversity, the creation of new and expansion of existing protected areas, the formation of the Emerald Network, the implementation of the regional ecological network of the Podillya region.
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