Local Interpretable Model-agnostic Explanations Research Articles

Early knee osteoarthritis classification using distributed explainable convolutional neural network with local interpretable model-agnostic explanations

Abstract Knee Osteoarthritis (KOA) is a type of Knee Arthritis (KA) that causes pain, swelling, and other discomforts to the knee joints, which is quite complicated to classify using previous methods due to its various limitations such as computational cost, over-fitting issues, less reliability and so on. In this research, the classification using a distributed explainable convolutional neural network with local interpretable model-agnostic explanations (LExNN) model is proposed for knee Osteoarthritis. The distributed LExNN model is an ensemble with a distributed mechanism, in which the input vectors are distributed to two explainable CNN which makes quite easier for classification and grading. The distributed concept is blown up with the number of advantages such as high computation speeds with less training time, reliability, and develop an efficient model for classification. In addition, the local interpretable model-agnostic explanations (LIME) technique interprets important information from the image and classifies the severity based on two grades namely high and low. This technique provides significant, simple, and understandable information, which is quite reliable for KOA classification. The supremacy of the model can be determined by measuring several parameters such as accuracy, precision, recall and f1 score that gives 99.25%, 99.25%, 98.42%, and 98.83% compared to other state-of-the-art methods.

Explainable AI for cyber security. Improving transparency and trust in intrusion detection systems

In recent years, the integration of Artificial Intelligence (AI) in cybersecurity has significantly enhanced the capabilities of Intrusion Detection Systems (IDS) to detect and mitigate sophisticated cyber threats. However, the increasing complexity and opaque nature of AI models have led to challenges in understanding, interpreting, and trusting these systems. This paper addresses the critical issue of transparency and trust in IDS by exploring the application of Explainable AI (XAI) techniques. By leveraging XAI, we aim to demystify the decision-making processes of AIdriven IDS, enabling security analysts to comprehend and validate the system's outputs effectively. The proposed framework integrates model-agnostic XAI methods, such as Local Interpretable Model-agnostic Explanations (LIME) and SHapley Additive exPlanations (SHAP), with state-of-the-art IDS algorithms to improve both interpretability and performance. Through comprehensive experiments on benchmark datasets, we demonstrate that our approach not only maintains high detection accuracy but also enhances the explainability of the model's decisions, thereby fostering greater trust among end-users. The findings of this study underscore the potential of XAI to bridge the gap between AI’s advanced capabilities and the human need for understanding, ultimately contributing to more secure and reliable cyber defense systems.

Skin Lesion Classification: A Deep Learning Approach with Local Interpretable Model-Agnostic Explanations (LIME) for Explainable Artificial Intelligence (XAI)

The classification of skin cancer is crucial as the chance of survival increases significantly with timely and accurate treatment. Convolution Neural Networks (CNNs) have proven effective in classifying skin cancer. However, CNN models are often regarded as "black boxes”, due to the lack of transparency in the decision-making. Therefore, explainable artificial intelligence (XAI) has emerged as a tool for understanding AI decisions. This study employed a CNN model, VGG16, to classify five skin lesion classes. The hyperparameters were adjusted to optimize its classification performance. The best hyperparameter settings were 50 epochs, a 0.1 dropout rate, and the Adam optimizer with a 0.001 learning rate. The VGG16 model demonstrated satisfactory classification performance. The Local Interpretable Model-Agnostic Explanations (LIME) method was implemented as the XAI tool to justify the predictions made by VGG16. The LIME explanation revealed that the correct predictions made by VGG16 were owing to its truthful extraction of the cancer or lesion area, especially for the “vascular lesion” class. Meanwhile, inaccurate classifications were attributed to VGG16 extraction of the background and insignificant parts of the skin as core features. In conclusion, The LIME model allowed visual inspection of the features selected by VGG16, paving the way for improving the CNN model for better feature extraction and classification of skin lesions, offering a promising direction for future research.

Explainable AI for News Classification

Abstract: The proliferation of news content across digital platforms necessitates robust and interpretable machine learning models to classify news into predefined categories effectively. This study investigates the integration of Explainable AI (XAI) techniques within the context of traditional machine learning models, including Naive Bayes, Logistic Regression, and Support Vector Machines (SVM), to achieve interpretable and accurate news classification. Utilizing the News Category Dataset, we preprocess the data to focus on the top 15 categories while addressing class imbalance challenges. Models are trained using Term Frequency-Inverse Document Frequency (TF-IDF) vectorization, achieving an acceptable classification accuracy of 67% across all models despite the complexity introduced by the high number of classes. To elucidate the decision-making processes of these models, we employ feature importance visualizations derived from model coefficients and feature log probabilities, complemented by local interpretability techniques such as LIME (Local Interpretable Model-agnostic Explanations). These methodologies enable granular insights into word-level contributions to predictions for each news category. Comparative heatmaps across models reveal significant consistencies and divergences in feature reliance, highlighting nuanced decision-making patterns. The integration of explainability into news classification provides critical interpretive capabilities, offering transparency and mitigating the risks associated with algorithmic opacity. The findings demonstrate how XAI enhances stakeholder trust by aligning model predictions with human interpretability, particularly in ethically sensitive domains. This work emphasizes the role of XAI in fostering responsible AI deployment and paves the way for future advancements, including deep learning integration and multilingual news classification with inherent interpretability frameworks

Improving syngas yield and quality from biomass/coal co-gasification using cooperative game theory and local interpretable model-agnostic explanations

The co-gasification of waste biomass and low-quality coal to produce syngas as fuel is an effective and sustainable approach in the waste-to-energy paradigm. The modeling of this process is however complex and time-consuming. The data-driven machine learning (ML) approaches enhanced with explainable artificial intelligence (XAI) are capable of solving this issue. Hence, in this study, five different ML techniques including Linear Regression (LR), Support Vector Regression (SVR), Gaussian Process Regression (GPR), Extreme Gradient Boosting (XGBoost), and Categorical Boosting (CatBoost) were employed for the model-prediction. The ultimate analysis, proximate analysis, and operation setting data were employed for the control factors syngas yield and lower heating value (LHV) prediction. The prediction results showed that XGBoost was superior to other ML approaches with an R2 value of 0.9786, mean squared error (MSE) of 10.82, and mean absolute percentage error (MAPE) of 9.8% during model testing of the syngas yield model. In the case of the syngas LHV model an R2 value of 0.9992, MSE of 0.03, and MAPE of 0.83% was observed. XGBoost was superior for both syngas yield and LHV models. The analysis of feature importance and its quantification was conducted by Shapley Additive Explanations (SHAP) and Local Interpretable Model-agnostic Explanations (LIME). SHAP and LIME approaches revealed that reaction temperature and biomass mixing ratio were the most important control factors for the syngas yield model.

SkinSage XAI: An explainable deep learning solution for skin lesion diagnosis.

Skin cancer poses a significant global health threat, with early detection being essential for successful treatment. While deep learning algorithms have greatly enhanced the categorization of skin lesions, the black-box nature of many models limits interpretability, posing challenges for dermatologists. To address these limitations, SkinSage XAI utilizes advanced explainable artificial intelligence (XAI) techniques for skin lesion categorization. A data set of around 50,000 images from the Customized HAM10000, selected for diversity, serves as the foundation. The Inception v3 model is used for classification, supported by gradient-weighted class activation mapping and local interpretable model-agnostic explanations algorithms, which provide clear visual explanations for model outputs. SkinSage XAI demonstrated high performance, accurately categorizing seven types of skin lesions-dermatofibroma, benign keratosis, melanocytic nevus, vascular lesion, actinic keratosis, basal cell carcinoma, and melanoma. It achieved an accuracy of 96%, with precision at 96.42%, recall at 96.28%, f 1 score at 96.14%, and an area under the curve of 99.83%. SkinSage XAI represents a significant advancement in dermatology and artificial intelligence by bridging gaps in accuracy and explainability. The system provides transparent, accurate diagnoses, improving decision-making for dermatologists and potentially enhancing patient outcomes.

Exploring the Impact of Image-Based Audio Representations in Classification Tasks Using Vision Transformers and Explainable AI Techniques

An important hurdle in medical diagnostics is the high-quality and interpretable classification of audio signals. In this study, we present an image-based representation of infant crying audio files to predict abnormal infant cries using a vision transformer and also show significant improvements in the performance and interpretability of this computer-aided tool. The use of advanced feature extraction techniques such as Gammatone Frequency Cepstral Coefficients (GFCCs) resulted in a classification accuracy of 96.33%. For other features (spectrogram and mel-spectrogram), the performance was very similar, with an accuracy of 93.17% for the spectrogram and 94.83% accuracy for the mel-spectrogram. We used our vision transformer (ViT) model, which is less complex but more effective than the proposed audio spectrogram transformer (AST). We incorporated explainable AI (XAI) techniques such as Layer-wise Relevance Propagation (LRP), Local Interpretable Model-agnostic Explanations (LIME), and attention mechanisms to ensure transparency and reliability in decision-making, which helped us understand the why of model predictions. The accuracy of detection was higher than previously reported and the results were easy to interpret, demonstrating that this work can potentially serve as a new benchmark for audio classification tasks, especially in medical diagnostics, and providing better prospects for an imminent future of trustworthy AI-based healthcare solutions.

An AI-assisted explainable mTMCNN architecture for detection of mandibular third molar presence from panoramic radiography

ObjectiveThis study aimed to design and systematically evaluate an architecture, proposed as the Explainable Mandibular Third Molar Convolutional Neural Network (E-mTMCNN), for detecting the presence of mandibular third molars (m-M3) in panoramic radiography (PR). The proposed architecture seeks to enhance the accuracy of early detection and improve clinical decision-making and treatment planning in dentistry. MethodsA new dataset, named the Mandibular Third Molar (m-TM) dataset, was developed through expert labeling of raw PR images from the UESB dataset. This dataset was subsequently made publicly accessible to support further research. Several advanced image preprocessing techniques, including Gaussian filtering, gamma correction, and data augmentation, were applied to improve image quality. Various Deep learning (DL) based Convolutional Neural Network (CNN) architectures were trained and validated using Transfer Learning (TL) methodologies. Among these, the E-mTMCNN, leveraging the GoogLeNet architecture, achieved the highest performance metrics. To ensure transparency in the model’s decision-making process, Local Interpretable Model-Agnostic Explanations (LIME) were integrated as an eXplainable Artificial Intelligence (XAI) approach. Clinical reliability and applicability were assessed through an expert survey conducted among specialized dentists using a decision support system based on the E-mTMCNN. ResultsThe E-mTMCNN architecture demonstrated a classification accuracy of 87.02%, with a sensitivity of 75%, specificity of 94.73%, precision of 77.68%, an F1 score of 75.51%, and an area under the curve (AUC) of 87.01%. The integration of LIME provided visual explanations of the model’s decision-making rationale, reinforcing the robustness of the proposed architecture. Results from the expert survey indicated high clinical acceptance and confidence in the reliability of the system. ConclusionThe findings demonstrate that the E-mTMCNN architecture effectively detects the presence of m-M3 in PRs, outperforming current state-of-the-art methodologies. The proposed architecture shows considerable potential for integration into computer-aided diagnostic systems, advancing early detection capabilities and enhancing the precision of treatment planning in dental practice.

Explainable artificial intelligence-machine learning models to estimate overall scores in tertiary preparatory general science course

Educational data mining is valuable for uncovering latent relationships in educational settings, particularly for predicting students' academic performance. This study introduces an interpretable hybrid model, optimised through Tree-structured Parzen Estimation (TPE) and Support Vector Regression (SVR), to predict overall scores (OT) utilising five assignments and one examination mark as predictors. Neural Network-based, Tree-Based, Ensemble-Based, and Boosting-based methods are evaluated against the hybrid TPE-optimised SVR model for forecasting final examination grades among 492 students enrolled in the TPP7155 (General Science) course at the University of Southern Queensland, Australia, during the 2020-2021 academic year. Additionally, Local Interpretable Model-agnostic Explanations (LIME) and SHapley Additive explanations (SHAP) techniques are employed to elucidate the inner workings of these prediction models. The findings highlight the superior performance of the proposed model, exhibiting the lowest Root Mean Squared Error (RMSE) and Relative Root Mean Squared Error (RRMSE), as well as the highest Willmott's index (WI), Legates–McCabe index (LM), and Nash–Sutcliffe Efficiency (NS). With assignment and examination marks identified as pivotal predictors of OT. SHAP and LIME analyses reveal the examination score (ET) as the most influential feature, impacting predicted OT by an average of ±4.93. Conversely, Assignment 1 emerges as the least informative feature, contributing merely ±0.64 to OT predictions. This research underscores the efficacy of the proposed interpretable hybrid TPE-optimised SVR model in discerning relationships among continuous learning variables, thereby empowering educators with early intervention capabilities and enhancing their ability to anticipate student performance prior to course completion.

JointLIME: An interpretation method for machine learning survival models with endogenous time-varying covariates in credit scoring.

In this work, we introduce JointLIME, a novel interpretation method for explaining black-box survival (BBS) models with endogenous time-varying covariates (TVCs). Existing interpretation methods, like SurvLIME, are limited to BBS models only with time-invariant covariates. To fill this gap, JointLIME leverages the Local Interpretable Model-agnostic Explanations (LIME) framework to apply the joint model to approximate the survival functions predicted by the BBS model in a local area around a new individual. To achieve this, JointLIME minimizes the distances between survival functions predicted by the black-box survival model and those derived from the joint model. The outputs of this minimization problem are the coefficient values of each covariate in the joint model, serving as explanations to quantify their impact on survival predictions. JointLIME uniquely incorporates endogenous TVCs using a spline-based model coupled with the Monte Carlo method for precise estimations within any specified prediction period. These estimations are then integrated to formulate the joint model in the optimization problem. We illustrate the explanation results of JointLIME using a US mortgage data set and compare them with those ofSurvLIME.

Explainable Deep Learning Approaches for Risk Screening of Periodontitis

Several pieces of evidence have been reported regarding the association between periodontitis and systemic diseases. Despite the emphasized significance of prevention and early diagnosis of periodontitis, there is still a lack of a clinical tool for early screening of this condition. Therefore, this study aims to use explainable artificial intelligence (XAI) technology to facilitate early screening of periodontitis. This is achieved by analyzing various clinical features and providing individualized risk assessment using XAI. We used 1,012 variables for a total of 30,465 participants data from National Health and Nutrition Examination Survey (NHANES). After preprocessing, 9,632 and 5,601 participants were left for all age groups and the over 50 y age group, respectively. They were used to train deep learning and machine learning models optimized for opportunistic screening and diagnosis analysis of periodontitis based on Centers for Disease Control and Prevention/ American Academy of Pediatrics case definition. Local interpretable model-agnostic explanations (LIME) were applied to evaluate potential associated factors, including demographic, lifestyle, medical, and biochemical factors. The deep learning models showed area under the curve values of 0.858 ± 0.011 for the opportunistic screening and 0.865 ± 0.008 for the diagnostic dataset, outperforming baselines. By using LIME, we elicited important features and assessed the combined impact and interpretation of each feature on individual risk. Associated factors such as age, sex, diabetes status, tissue transglutaminase, and smoking status have emerged as crucial features that are about twice as important than other features, while arthritis, sleep disorders, high blood pressure, cholesterol levels, and overweight have also been identified as contributing factors to periodontitis. The feature contribution rankings generated with XAI offered insights that align well with clinically recognized associated factors for periodontitis. These results highlight the utility of XAI in deep learning–based associated factor analysis for detecting clinically associated factors and the assistance of XAI in developing early detection and prevention strategies for periodontitis in medical checkups.

Machine learning approaches for predicting and diagnosing chronic kidney disease: current trends, challenges, solutions, and future directions.

Chronic Kidney Disease (CKD) represents a significant global health challenge, contributing to increased morbidity and mortality rates. This review paper explores the current landscape of machine learning (ML) techniques employed in CKD prediction and diagnosis, highlighting recent trends, inherent challenges, innovative solutions, and future directions. Through an extensive literature survey, we identified key limitations and challenges, including the use of small datasets, the absence of stage-specific predictions, insufficient focus on model interpretability, and a lack of discussions on safeguarding patient privacy in managing sensitive CKD data. We considered these limitations and challenges as research gaps, and this review paper aims to address them. We emphasize the potential of Generative AI to augment dataset sizes, thereby enhancing model performance and reliability. To address the lack of stage-specific predictions, we highlight the need for effective multi-class models to accurately predict CKD stages, enabling tailored treatments and improved patient outcomes. Furthermore, we discuss the critical importance of model interpretability, utilizing methods such as SHAP (SHapley Additive exPlanations) and LIME (Local Interpretable Model-agnostic Explanations) to ensure transparency and trust among healthcare professionals. Privacy concerns surrounding sensitive patient data are also addressed. We present innovative privacy-preserving solutions using technologies, such as homomorphic encryption, federated learning, and blockchain. These solutions facilitate collaboration across institutions while maintaining patient confidentiality and addressing challenges related to limited generalizability and reproducibility in CKD prediction. This review informs healthcare professionals and researchers about advancements in ML for CKD prediction, to improve patient outcomes and address research gaps.

Machine learning for predicting in-hospital mortality in elderly patients with heart failure combined with hypertension: a multicenter retrospective study

BackgroundHeart failure combined with hypertension is a major contributor for elderly patients (≥ 65 years) to in-hospital mortality. However, there are very few models to predict in-hospital mortality in such elderly patients. We aimed to develop and test an individualized machine learning model to assess risk factors and predict in-hospital mortality in in these patients.MethodsFrom January 2012 to December 2021, this study collected data on elderly patients with heart failure and hypertension from the Chongqing Medical University Medical Data Platform. Least absolute shrinkage and the selection operator was used for recognizing key clinical variables. The optimal predictive model was chosen among eight machine learning algorithms on the basis of area under curve. SHapley Additive exPlanations and Local Interpretable Model-agnostic Explanations was employed to interpret the outcome of the predictive model.ResultsThis study ultimately comprised 4647 elderly individuals with hypertension and heart failure. The Random Forest model was chosen with the highest area under curve for 0.850 (95% CI 0.789–0.897), high accuracy for 0.738, recall 0.837, specificity 0.734 and brier score 0.178. According to SHapley Additive exPlanations results, the most related factors for in-hospital mortality in elderly patients with heart failure and hypertension were urea, length of stay, neutrophils, albumin and high-density lipoprotein cholesterol.ConclusionsThis study developed eight machine learning models to predict in-hospital mortality in elderly patients with hypertension as well as heart failure. Compared to other algorithms, the Random Forest model performed significantly better. Our study successfully predicted in-hospital mortality and identified the factors most associated with in-hospital mortality.

Explainable Pre-Trained Language Models for Sentiment Analysis in Low-Resourced Languages

Sentiment analysis is a crucial tool for measuring public opinion and understanding human communication across digital social media platforms. However, due to linguistic complexities and limited data or computational resources, it is under-represented in many African languages. While state-of-the-art Afrocentric pre-trained language models (PLMs) have been developed for various natural language processing (NLP) tasks, their applications in eXplainable Artificial Intelligence (XAI) remain largely unexplored. In this study, we propose a novel approach that combines Afrocentric PLMs with XAI techniques for sentiment analysis. We demonstrate the effectiveness of incorporating attention mechanisms and visualization techniques in improving the transparency, trustworthiness, and decision-making capabilities of transformer-based models when making sentiment predictions. To validate our approach, we employ the SAfriSenti corpus, a multilingual sentiment dataset for South African under-resourced languages, and perform a series of sentiment analysis experiments. These experiments enable comprehensive evaluations, comparing the performance of Afrocentric models against mainstream PLMs. Our results show that the Afro-XLMR model outperforms all other models, achieving an average F1-score of 71.04% across five tested languages, and the lowest error rate among the evaluated models. Additionally, we enhance the interpretability and explainability of the Afro-XLMR model using Local Interpretable Model-Agnostic Explanations (LIME) and Shapley Additive Explanations (SHAP). These XAI techniques ensure that sentiment predictions are not only accurate and interpretable but also understandable, fostering trust and reliability in AI-driven NLP technologies, particularly in the context of African languages.

Enhancing misogyny detection in bilingual texts using explainable AI and multilingual fine-tuned transformers

Gendered disinformation undermines women’s rights, democratic principles, and national security by worsening societal divisions through authoritarian regimes’ intentional weaponization of social media. Online misogyny represents a harmful societal issue, threatening to transform digital platforms into environments that are hostile and inhospitable to women. Despite the severity of this issue, efforts to persuade digital platforms to strengthen their protections against gendered disinformation are frequently ignored, highlighting the difficult task of countering online misogyny in the face of commercial interests. This growing concern underscores the need for effective measures to create safer online spaces, where respect and equality prevail, ensuring that women can participate fully and freely without the fear of harassment or discrimination. This study addresses the challenge of detecting misogynous content in bilingual (English and Italian) online communications. Utilizing FastText word embeddings and explainable artificial intelligence techniques, we introduce a model that enhances both the interpretability and accuracy in detecting misogynistic language. To conduct an in-depth analysis, we implemented a range of experiments encompassing classic machine learning methodologies and conventional deep learning approaches to the recent transformer-based models incorporating both language-specific and multilingual capabilities. This paper enhances the methodologies for detecting misogyny by incorporating incremental learning for cutting-edge datasets containing tweets and posts from different sources like Facebook, Twitter, and Reddit, with our proposed approach outperforming these datasets in metrics such as accuracy, F1-score, precision, and recall. This process involved refining hyperparameters, employing optimization techniques, and utilizing generative configurations. By implementing Local Interpretable Model-agnostic Explanations (LIME), we further elucidate the rationale behind the model’s predictions, enhancing understanding of its decision-making process.

An Explainable Data-Driven Optimization Method for Unmanned Autonomous System Performance Assessment

Unmanned autonomous systems (UASs), including drones and robotics, are widely employed across various fields. Despite significant advances in AI-enhanced intelligent systems, there remains a notable deficiency in the interpretability and comprehensive quantitative evaluation of these systems. The existing literature has primarily focused on constructing evaluation frameworks and methods, but has often overlooked the rationality and reliability of these methods. To address these challenges, this paper proposes an innovative optimization evaluation method for data-driven unmanned autonomous systems. By optimizing the weights of existing indicators based on data distribution characteristics, this method enhances the stability and reliability of assessment outcomes. Furthermore, interpretability techniques such as Local Interpretable Model-agnostic Explanations (LIMEs) and Partial Dependence Plots (PDPs) were employed to verify the effectiveness of the designed evaluation indicators, thereby ensuring the robustness of the evaluation system. The experimental results validated the effectiveness of the proposed approach.

Utilization of Machine Learning and Explainable Artificial Intelligence (XAI) for Fault Prediction and Diagnosis in Wafer Transfer Robot

Faults in the wafer transfer robots (WTRs) used in semiconductor manufacturing processes can significantly affect productivity. This study defines high-risk components such as bearing motors, ball screws, timing belts, robot hands, and end effectors, and generates fault data for each component based on Fluke’s law. A stacking classifier was applied for fault prediction and severity classification, and logistic regression was used to identify fault components. Additionally, to analyze the frequency bands affecting each failed component and assess the severity of faults involving two mixed components, a hybrid explainable artificial intelligence (XAI) model combining Shapley additive explanations (SHAP) and local interpretable model-agnostic explanations (LIME) was employed to inform the user about the component causing the fault. This approach demonstrated a high prediction accuracy of 95%, and its integration into real-time monitoring systems is expected to reduce maintenance costs, decrease equipment downtime, and ultimately improve productivity.

Explainable machine learning methods to predict postpartum depression risk

Postpartum depression (PPD) is a type of depression that mothers have following childbirth due to hormonal changes, psychological transition to parenting, and exhaustion. This depression strikes either during/or in the first year following childbirth. It is also a frequently disregarded medical condition that must be treated right away as it might have major repercussions. Machine learning (ML) and artificial intelligence (AI) are tools that healthcare professionals can utilize to anticipate this condition more rapidly and correctly. Consequently, we have demonstrated how to use explainable artificial intelligence (XAI) methods and heterogeneous classifiers to predict postpartum depression in mothers who have recently given birth. The K-Nearest Neighbor (KNN) model and the customized stack model outperformed all other classifiers. KNN model obtained 97% accuracy, 98% recall, and 95% precision and the stack model obtained 97% accuracy, 100% recall, and 94% precision, respectively. A set of frameworks and resources known as explainable artificial intelligence (XAI) facilitates the comprehension and interpretation of predictions made by machine learning algorithms. Four distinct XAI techniques: ELI5, Shapley Additive Values (SHAP), Local Interpretable Model-agnostic Explanations (LIME), and Anchor – have been used to interpret the model predictions. Explainability, interpretability, accountability, and transparency are crucial parameters of XAI, ensuring that machine learning models provide understandable and trustworthy results to users and stakeholders. The goal of this interdisciplinary research is to develop an automated diagnosis framework with tools that can transform therapy for postpartum depression leading to suicide attempts and empower medical professionals to offer mothers individualized, high-quality care.

Sequential gated recurrent and self attention explainable deep learning model for predicting hydrogen production: Implications and applicability

To meet the difficulties of the current energy environment, hydrogen has enormous potential as a clean and sustainable energy source. Utilizing hydrogen's potential requires accurate hydrogen production prediction. Due to its capacity to identify intricate patterns in data, Machine learning alongside deep learning models has attracted considerable interest from a variety of industries, including the energy industry. Although these models yield an acceptable performance, there is still a need to improve their prediction results. Also, they are inherently black boxes, which makes it difficult to comprehend and interpret their predictions, particularly in important sectors like hydrogen generation. Sequel to the above, a sequential gated recurrent and self-attention network is proposed in this study to enhance hydrogen production prediction. The framework captures both sequential dependencies and contextual information enabling the model to effectively learn and represent temporal patterns in hydrogen production prediction. The biomass gasification dataset is used for the experiment including the Mean Absolute Error (MAE), Mean Squared Error (MSE), Root Mean Squared Error (RMSE), Coefficient of Determination (R2), Mean Squared Logarithmic Error (MSLE) and Root Mean Squared Logarithmic Error (RMSLE) evaluation metrics. The proposed model recorded an optimal performance with an MAE of 0.102, MSE of 0.027, RMSE of 0.160, R2 of 0.999, MSLE of 0.001, and RMSLE of 0.030 based on K-cross validation. Among the input features, the percentage of plastics in the mixture(wt%) and RSS Particle Size(mm) are identified to be the most influential features in the proposed model prediction as identified by Shapley Additive Explanation (SHAP), Local Interpretable Model-Agnostic Explanations (LIME) and Feature importance plot. With 99.99 % of the data points for H2 production found within the range of reliability, the model demonstrates robust predictive capability with the majority of observations exerting minimal leverage (0 ≤ u ≤ [leverage threshold]) and limited influence (0 ≤ H ≤ [cooks' threshold]) on the predictive outcome using the modified William plot. Furthermore, various visualization approaches like Matthews correlation coefficient and Tarloy charts were adapted for the result explanations. The proposed model results were compared with state-of-the-art models exploring the significance of the proposed model in providing insights into the underlying mechanisms and factors influencing hydrogen production processes hence improving human understanding of the relationships between input factors and hydrogen production outputs as well as bridging the gap between predicted accuracy and interpretability.

Development and Validation of Deep Learning-Based Infectivity Prediction in Pulmonary Tuberculosis Through Chest Radiography: Retrospective Study.

Pulmonary tuberculosis (PTB) poses a global health challenge owing to the time-intensive nature of traditional diagnostic tests such as smear and culture tests, which can require hours to weeks to yield results. This study aimed to use artificial intelligence (AI)-based chest radiography (CXR) to evaluate the infectivity of patients with PTB more quickly and accurately compared with traditional methods such as smear and culture tests. We used DenseNet121 and visualization techniques such as gradient-weighted class activation mapping and local interpretable model-agnostic explanations to demonstrate the decision-making process of the model. We analyzed 36,142 CXR images of 4492 patients with PTB obtained from Severance Hospital, focusing specifically on the lung region through segmentation and cropping with TransUNet. We used data from 2004 to 2020 to train the model, data from 2021 for testing, and data from 2022 to 2023 for internal validation. In addition, we used 1978 CXR images of 299 patients with PTB obtained from Yongin Severance Hospital for external validation. In the internal validation, the model achieved an accuracy of 73.27%, an area under the receiver operating characteristic curve of 0.79, and an area under the precision-recall curve of 0.77. In the external validation, it exhibited an accuracy of 70.29%, an area under the receiver operating characteristic curve of 0.77, and an area under the precision-recall curve of 0.8. In addition, gradient-weighted class activation mapping and local interpretable model-agnostic explanations provided insights into the decision-making process of the AI model. This proposed AI tool offers a rapid and accurate alternative for evaluating PTB infectivity through CXR, with significant implications for enhancing screening efficiency by evaluating infectivity before sputum test results in clinical settings, compared with traditional smear and culture tests.