PurposePrevious studies examined the effect of inter-organizational collaboration relationships on organizational innovation. However, most focused on the configuration of the network from the static network perspective, and few examined the influence of network structure stability on an organization's exploratory innovation from the ego-network perspective. This study addresses this research gap by focusing on ego-network stability and its effect on an organization's exploratory innovation.Design/methodology/approachThe empirical setting is the smartphone collaboration network from 2004 to 2017. We selected one-site schemes and panel data of patents from the Derwent Innovation Database. A negative binomial model with fixed effects was used to test our hypotheses.FindingsThe regression results show that an organization's ego-network stability has an inverted-U-shaped relationship with its exploratory innovation. Global cohesion of the focal organization's knowledge network moderates the process in such a way that when it is at a high level, an organization's exploratory innovation can benefit more from a moderate level of ego-network stability. However, local cohesion moderates in such a way that, at a low level, an organization's exploratory innovation can benefit more from a moderate level of ego-network stability.Originality/valueThis study highlights the importance of ego-network stability and its effect on the focal organization's exploratory innovation. It contributes to the literature on the relationship between ego-network stability and exploratory innovation by investigating the moderating role of global cohesion and local cohesion in knowledge networks.