Loading Protocol Research Articles

The Effect of Increasing Thread Depth on the Initial Stability of Dental Implants: An In Vitro Study

Background: The long-term success of dental implants largely depends on achieving primary stability, previously described as crucial to obtaining osseointegration and immediate loading protocol requirements. Implant thread depths seem to be one of the key factors influencing primary stability, particularly in low-density bone. Insertion torque (IT) and resonance frequency analysis (RFA) are considered the most reliable tests to assess primary stability. The aim of this work was to evaluate how different thread depths of commercially available dental implants affect primary stability in low-density D3 bone. Materials and Methods: An in vitro study was carried out between February 2024 and March 2024. Twenty-four dental implants were divided into four groups (six implants each) according to their thread depths (Group A: 4 mm, Group B: 4.5 mm, Group C: 5 mm, Group D: 5.5 mm) and were inserted in D3-type artificial bone blocks. The main outcome variables were the IT and the Implant Stability Quotient (ISQ) measured in four different areas of the implant (buccal, lingual, mesial, and distal) with an Osstel® ISQ reader. Descriptive and inferential analyses of the data were performed, and the significance value was set at 5%. Results: A total of 24 implants were analyzed. The highest IT values were obtained in Group D, with a mean of 54.03 Ncm (standard deviation (SD) = 8.99), while the lowest measurements were observed in Group A (mean = 25.12; SD: 2.96 N.cm). The mean ISQ values were consistently higher in Group D for each analyzed area, with a mean of 70.13 N.cm (SD = 1.12). Conclusions: Taking into consideration the limitations of this in vitro study, greater thread depths seem to increase the primary stability of dental implants placed in soft bone. Furthermore, a positive correlation was observed between all IT and ISQ values, regardless of the thread depth.

Abstract MP34: Muscle Sodium Content and Isolevuglandin Formation in Antigen Presenting Cells in Human Salt Sensitive Hypertension

Background: Salt sensitivity of blood pressure (SSBP) is an independent risk factor for cardiovascular mortality. However, the mechanisms by which salt exposure affects blood pressure in SSBP are still unclear. We have shown that under high sodium (Na + ) concentrations, Na + enters antigen-presenting cells (APCs) via epithelial Na + channel (ENaC), which leads to isolevuglandin (IsoLG) production and hypertension. Baseline %IsoLG+ APC correlates with SSBP. While the exact location where APCs are activated by salt and trigger an inflammatory response remains to be elucidated, muscle and skin are proposed as potential sites. We hypothesize that muscle and skin Na + levels are associated with SSBP. Methods: We assessed SSBP in 30 hypertensive subjects using an inpatient salt loading and depletion protocol. Flow cytometry was used to identify IsoLG-containing APCs; dendritic cells (DCs), classic (CD14+16-), non-classic (CD14-16+), and intermediate (CD14+16+) monocytes. Salt loading was achieved through saline infusion and a high-salt diet (460mmol/24 hours), while salt depletion was achieved via diuretic administration (furosemide 40mg x3) and a low-salt diet (10mmol/24hours). Baseline muscle and skin Na + levels were assessed with the 23 Na MRI technique. Spearman's correlation was used to analyze the associations. Demographic data are presented with mean and standard error of the mean. Results: Participants’ age was 53 ± 1.34 years, 53% female, baseline blood pressure was 140.2 ± 2.62 / 87.30 ± 1.77 mmHg, and salt sensitivity index was 3.72 ± 1.4 mmHg. We found an inverse correlation between baseline muscle Na + levels and the decrease in IsoLGs from salt loading to depletion (ΔIsoLGs) in DCs (r=-0.50, p=0.007), intermediate (r=-0.42 p=0.0284) and non-classic monocytes (r=-0.39 p=0.0432), but not in classical monocytes. Skin Na + levels were not correlated with any of these measures. There was a decreasing trend of salt sensitivity index with increasing muscle Na + , although this correlation did not reach statistical significance (r=-0.35 p=0.0686) Conclusion: This highlights the potential importance of muscle Na + in SSBP, such that patients with lower muscle Na + exhibited a higher trend of salt sensitivity index and increased variability in IsoLG+ APCs. Moreover, baseline tissue Na + assessment may emerge as a potential tool for evaluating the degree of salt sensitivity and IsoLG activation in SSBP.

Abstract P177: High salt modulates Antigen Presenting Cell TNF-alpha production in an Isolevuglandin-dependent manner in Hypertensive Humans

Salt intake is a predisposing factor to high blood pressure in people with salt sensitivity, but the mechanisms are not fully understood. Previously, we found that the epithelial sodium channel facilitates sodium entry into antigen-presenting cells (APCs), leading to the production of Isolevuglandins (IsoLGs) and hypertension via proinflammatory cytokines. TNF-alpha is a major proinflammatory cytokine that is produced in response to oxidative stress. We hypothesize that high salt intake-associated increased production of IsoLGs activates TNF-alpha-dependent mechanisms to contribute to salt-sensitive hypertension. To test this hypothesis, we conducted bulk RNA sequencing on isolated human monocytes with and without high salt. We also performed in vivo studies on humans living with hypertension using the rigorous Weinberger salt loading and depletion protocol at baseline (B), salt loading (SL), and salt depletion (SD) timepoints. We found that in vitro high salt treatment increased human monocyte expression of TNF-α, TNFRSF1A and TNFRSF1B (117.09 ± 23.71 vs 357.82 ± 59.62, p=0.001; 4560 ± 430.02 vs 6189 ± 461.11, p=0.0014 and 43824.73 ± 6462.55 vs 54585.64 ± 5383.58, p=0.0336 respectively, [n=11]) when compared to normal salt. In vivo studies on 16 hypertensive subjects reveal mean blood pressures as baseline (SBP: 137.7 ± 3.1, DBP: 85±2.2, MAP 104.7±2.1 [mmHg]), salt-loading (SBP: 141.3 ± 2.9, DBP: 86.1±2.3, MAP 105.6±2.2 [mmHg]), and salt-depletion (SBP: 138.7 ± 2.9, DBP: 87±2.4, MAP 104.7±2.1 [mmHg]). Using flow cytometry, we determined the buildup of Isolevuglandin adducts in APCs as follows: B: 57.6±6.4, SL: 59.8±4.6, SD: 46.0±7.1 (dendritic cells); B: 78.6±5.8, SL: 77.3±5.7, SD: 61.0±6.9 (CD14 + cells); B: 83.2±4.9, SL: 74.0±6.4, SD: 63.3±8.2 (CD14 + 16 + cells) and B: 63.3± 5.7, SL: 54.2±6.1, SD: 46.8±7.9 (CD16+ cells). In response to salt loading, patient plasma levels of TNF-α were B: 13.8±0.5 pg/mL, SL: 14.1±0.6 pg/mL, and SD: 15.3±1.2 pg/mL respectively. Finally, in vivo single-cell transcriptomic analysis in peripheral blood mononuclear cells revealed that in response to high salt treatment, TNF expression changes dynamically with blood pressure in salt-sensitive, but not salt-resistant patients. These preliminary findings suggest that TNF-α plays a role in salt-sensitive hypertension, possibly following IsoLG-driven reactive oxygen species generation. Further studies are needed to delineate specific dependent mechanisms by which this occurs.

Cyclic behavior of cold-formed stainless steel sandwich tubular brace: An experimental investigation

Stainless steel shows promise for application in seismic-active regions. Previous research showed that stainless steel dampers could exhibit good energy dissipation capacity and high post-yield stiffness under cyclic loading. In light of that, a novel type of cold-formed stainless steel sandwich tubular brace (STB) is presented in this study, featuring one stainless steel square hollow section (SHS) tube as the load-carrying component and two additional stainless steel SHS tubes providing a buckling-restraining effect. Six specimens were tested under cyclic loading, varying parameters including the cross-section slenderness of the core tube, restraining ratio and loading histories. Loading protocols encompassed standardized ones following the Chinese specification (CN) and American provision (US), as well as a protocol representing the near-fault earthquakes (NF). Failure modes, hysteretic response and seismic performance indexes were obtained. Results showed that the hysteretic curves could maintain stable. Under the CN loading protocol, the specimen with a slender core cross-section exhibited uniform local buckling. The strain hardening coefficient ω stayed within the range of 1.46–1.58. The specimens exhibited a slow decay rate of tangent stiffness, highlighting their relatively high post-yield stiffness. The cumulative energy dissipation factor could reach 658, signifying good energy dissipation capacity. Additionally, under NF loading, specimens exhibited enhanced cumulative ductility compared to CN or US loading. Furthermore, an evaluation was conducted to assess the suitability of existing design methods for preventing overall buckling and local bulging in stainless steel STBs. It indicated that the current design approaches tended to be overly conservative for both overall and local stability design of stainless steel STBs, primarily due to the lack of consideration for SHS core stiffness and the interactions between flanges and webs, respectively.

Assessment and Rehabilitation Strategies for Sports-Related Musculoskeletal Injuries

This study provides a comprehensive analysis of assessment methods and rehabilitation techniques for sports activities-related musculoskeletal accidents. Understanding the complexity and variety of injuries incurred in sports, this paper synthesizes the modern-day evidence-based practices and protocols used to assess such injuries. Assessment processes embody a multidimensional exam, consisting of physical examination techniques, imaging modalities, and practical checks, aiming to diagnose the extent and nature of the harm precisely. Furthermore, the evaluation examines into rehabilitation strategies tailor-made to precise accidents, emphasizing the importance of a holistic approach that integrates therapeutic physical activities, manual therapy, neuromuscular re-schooling, and modern loading protocols. A minimum of 200 participants, comprising athletes with various types of musculoskeletal injuries, will be recruited to ensure diversity and generalizability of findings. Participants will be randomly assigned to intervention and control groups using computer-generated random numbers to ensure an unbiased allocation process. Stratification based on injury type and severity will be employed as a criteria, ensuring a balanced distribution of participants across different categories. Participants will undergo rehabilitation sessions three times per week for a duration of eight weeks, ensuring a structured and progressive approach to musculoskeletal injury recovery. Special attention is given to individualized rehabilitation plans that consider the athlete's sport-specific needs, biomechanics, and psychological aspects, facilitating the most beneficial restoration and secure return to play. The paper concludes by highlighting the ongoing advancements in generation and treatment modalities that similarly enhance the evaluation accuracy and efficacy of rehabilitation interventions for sports-related musculoskeletal injuries, emphasizing the importance of a comprehensive and customized method in the management of such injuries.

Effect of loading sequence on the ultra-low-cycle fatigue performance of all-steel BRBs

Buckling-restrained braces (BRBs) are intended to protect the primary structure of buildings by absorbing most earthquake input energy through the plastic deformation of the steel cores. The ultra-low-cycle fatigue performance of BRBs is crucial for their seismic performance as energy dissipators. Despite the plenty of research on the ultra-low-cycle fatigue behavior of steel members, it remains susceptible if arbitrary loading paths have a major effect on the ultra-low-cycle fatigue life or cumulative plastic deformation (CPD) capacity of BRBs. This paper introduces an experimental campaign of nine supposedly identical BRB specimens subjected to three different loading protocols of similar average strain amplitudes. For each loading protocol, the test was repeated for three times to account for possible uncertainty. The results show that the effect of loading protocol is trivial given the similar average strain amplitudes throughout the loading. The Miner's assumption that the loading sequence has no effect on the fatigue life of BRBs is supported by the test results, however, the proper choice of the Coffin-Masson model's parameters is crucial. The skeleton ratio, which is derived from decomposing the hysteresis curve into a skeleton part and a Bauschinger part and has been used to account for the loading path effects, is shown to be insensitive to varied loading protocols by the test results.

Advanced cyclic constitutive model and parameter calibration method for austenitic stainless steel

Austenitic stainless steel is recognized for its potential in improving structural seismic resistance due to its exceptional ductility. This study seeks to analyse the material characteristics and cyclic constitutive model of austenitic stainless steel under cyclic loading using a combination of experiments and numerical studies. The primary goal is to enhance the precision of numerical simulations predicting the seismic performance of stainless steel and to minimize the costs associated with calibrating the parameters of the cyclic constitutive model. By conducting cyclic loading experiments on stainless steel with different plate thicknesses, the hysteresis curves under different loading protocols were obtained. The loading protocol significantly influences the cyclic hardening behaviour of stainless steel. To calibrate material parameters in the Chaboche model more effectively, a new parameter calibration method based on genetic algorithm optimization is proposed. Additionally, a method is proposed to calibrate the material parameters of the Hu model by utilizing the monotonic tensile stress-strain curve of austenitic stainless steel, which provides a new material model option for the numerical simulation of stainless steel seismic performance. The applicability of the Chaboche model and the Hu model in numerical simulations of stainless steel members is then verified and compared using existing seismic performance test results. The findings indicate that the Hu model offers more accurate numerical simulations of cyclic loading on austenitic stainless steel members compared to the Chaboche model.

Seismic behavior and resilience assessment of prefabricated beam–column joint with replaceable graded-yielding energy-dissipating connectors

Conventionally assembled monolithic concrete frame structures achieve structural ductility through beam-end failure, which results in structures that are difficult to repair after an earthquake. To improve the seismic and resilience performance, a prefabricated concrete beam–column joint with replaceable graded-yielding energy-dissipating connectors (RGECs) is introduced. The connectors assembled on the upper and lower sides of the beam end dissipate energy and transfer the beam-end load with the steel hinge device. By adjusting the design bearing-capacity coefficient of RGECs to precast beams, the plasticity and damage of the structure can be centered on the core energy-dissipation bending–shear components (BSCs) and buckling segment (BS) of the RGEC, and the structural function can be quickly recovered by replacing only the damaged RGECs after a seismic disaster. Moreover, compared to the conventional joints, the joint with RGEC can achieve target seismic-performance goals at different seismic-risk levels by designing BSCs and BS with graded yielding. Low-cyclic-loading tests were performed on seven full-scale beam–column joint specimens to investigate the effects of different core energy-dissipating member thicknesses, beam reinforcement ratios and loading protocols on the seismic behavior of the proposed joint. Subsequently, the damaged RGECs were replaced, and the structural-function resilience performance was evaluated in terms of the function-recovery efficiency and quality, indicated by the hysteresis response, strain development, and component energy dissipation. The experimental results proved that the beam–column joint exhibited excellent seismic performance and could realize graded-yielding energy dissipation. The damage to the specimens was concentrated in the RGECs, the key members (beams and columns) were in an elastic state, and the energy dissipation ratio of the RGEC was more than 97 %. This enables the rapid recovery of function after earthquakes. After replacing the RGEC, the hysteresis response, strain development, and component energy dissipation of the specimens were consistent with those of the initial specimens. Compared with the original specimen, the difference in each seismic index of the replaced specimen was less than 10 %. Additionally, the structural function recovered quickly, and the resilient performance was good.

Segment test to investigate early age movement in grouted connections of offshore wind turbines

Cementitious grout materials are regularly used in structural – and especially in wind energy engineering – as filler material e.g. when joining metallic building members. During the hardening process, it is crucial to protect the grout material from any mechanical agitation, the so called ‘early age movement’, which is not always possible. Previous research showed indifferent results regarding the impact of early age movement on grouted connections. The occurring damage phenomena were not fully understood. To close this knowledge gap, a novel test setup is developed to investigate, how early age movement influences the material and interface properties of cementitious materials in composite connections using the example of grouted connections. A simplified mechanical model depicting the grout stiffness development during hydration is introduced to analyse load redistributions and realistic loading of the grout at different points in time. Comparing two loading protocols reveals a severe difference in the stress distribution experienced by the grout. Loading and transition boundaries play a decisive role for possible damage phenomena. The results of a test under axial and lateral early age movement are analysed according to load redistributions and hysteresis development, showing that the stiffening grout continuously reduced the movement until an intact bond is reached. However, analyses of samples subjected to early age movement indicate a slight reduction of their compressive strength.

Presoaking hamstring autograft with vancomycin does not jeopardize its biomechanical properties, including graft elongation, after cyclic loading.

Presoaking the graft with vancomycin before implantation has been shown to reduce the risk of postoperative infection after anterior cruciate ligament reconstruction (ACLR). However, the effects of presoaking on the graft biomechanical properties remain unclear. This study aimed to determine whether presoaking the graft with vancomycin affects the graft biomechanical properties and length after cyclic loading. Ten paired (20 specimens) gracilis and semitendinous tendons were harvested from fresh-frozen human cadaveric specimens. Two tendons were folded in half to make four strands, and the grafts were randomized into the vancomycin and control groups. The graft was exposed to the antibiotic solution for 15 min (5 mg/mL) and prepared by mixing 1 g of vancomycin with 200 mL of normal saline (NaCl 0.9%). The control group was soaked in normal saline for 15 min. The prepared grafts were attached to the actuator of a dynamic tensile-testing machine. All grafts were tested with 3000 cycles of cyclic loading followed by a pull-to-failure. The cyclic loading protocol consisted of position and load control blocks to simulate the graft in vivo in the postoperative phase after ACLR. Presoaking in vancomycin did not jeopardize the biomechanical properties of the graft. In addition, presoaking with vancomycin did not elongate the grafts. No significant differences were found in the mean Young's modulus and the mean total elongation of the graft of the specimen between the vancomycin group and the control group. Presoaking the graft with vancomycin jeopardized neither its biomechanical properties nor elongation even after cyclic loading in this in vitro study. It is suggested that vancomycin presoaking could be considered a safe and effective preventive measure for postoperative infections after ACLR. Not applicable.

Homogenized finite element simulations can predict the primary stability of dental implants in human jawbone

Adequate primary stability is a pre-requisite for the osseointegration and long-term success of dental implants. Primary stability depends essentially on the bone mechanical integrity at the implantation site. Clinically, a qualitative evaluation can be made on medical images, but finite element (FE) simulations can assess the primary stability of a bone-implant construct quantitatively based on high-resolution CT images. However, FE models lack experimental validation on clinically relevant bone anatomy. The aim of this study is to validate such an FE model on human jawbones. Forty-seven bone biopsies were extracted from human cadaveric jawbones. Dental implants of two sizes (Ø3.5 mm and Ø4.0 mm) were inserted and the constructs were subjected to a quasi-static bending-compression loading protocol. Those mechanical tests were replicated with sample-specific non-linear homogenized FE models. Bone was modeled with an elastoplastic constitutive law that included damage. Density-based material properties were mapped based on μCT images of the bone samples. The experimental ultimate load was better predicted by FE (R2 = 0.83) than by peri-implant bone density (R2 = 0.54). Unlike bone density, the simulations were also able to capture the effect of implant diameter. The primary stability of a dental implant in human jawbones can be predicted quantitatively with FE simulations. This method may be used for improving the design and insertion protocols of dental implants.

Uniaxial material model with softening for simulating the cyclic behavior of steel tubes in concrete‐filled steel tube beam‐columns

AbstractThis paper presents a new uniaxial constitutive material formulation with softening for simulating the inelastic behavior of steel rectangular tubes in concrete‐filled steel tube (CFST) members. The primary behavioral characteristics of the steel tube in CFST members are isolated and pronounced through a carefully designed experimental campaign with CFST specimens subjected to uniaxial strain‐based loading protocols. The model is expressed in an effective stress–strain domain, where the effective uniaxial strain is defined as the uniaxial displacement within a dissipative zone over a predefined length. In the pre‐peak state, the proposed model can effectively capture the combined kinematic/isotropic hardening and Bauschinger effect—characteristic of mild structural steels—within the framework of rate‐independent plasticity. In the post‐peak state, the proposed model traces strength deterioration due to outward local buckling, which is a characteristic nonlinear geometric instability in CFST members due to the presence of the filled concrete in the steel tube. The proposed constitutive formulation incorporates a softening branch that exponentially decays to trace the stabilization of the outward buckling wave within the buckling region in successive inelastic loading cycles. Cyclic deterioration of the effective stress is explicitly considered via an energy‐based rule. The proposed model is calibrated to a CFST dataset. Regression equations are proposed for predicting the input model parameters. These equations cover a wide range of geometric parameters and structural steel materials in CFST members. Comparisons with prior tests on actual CFST beam‐columns under planar symmetric cyclic loading suggest that conventional 2‐dimensional displacement‐based beam‐column elements can predict the full‐range of the hysteretic behavior of the CFST members with the proposed constitutive formulation including cases where the post‐peak response of CFST members exhibits negative stiffness.

Cryopreserving the intact intervertebral disc without compromising viability.

Tissue cryopreservation requires saturation of the structure with cryoprotectants (CPAs) that are also toxic to cells within a short timeframe unless frozen. The race between CPA delivery and cell death is the main barrier to realizing transplantation banks that can indefinitely preserve tissues and organs. Unrealistic cost and urgency leaves less life-threatening ailments unable to capitalize on traditional organ transplantation systems that immediately match and transport unfrozen organs. For instance, human intervertebral discs (IVD) could be transplanted to treat back pain or used as ex vivo models for studying regenerative therapies, but both face logistical hurdles in organ acquisition and transport. Here we aimed to overcome those challenges by cryopreserving intact IVDs using compressive loading and swelling to accelerate CPA delivery. CPAs were tested on bovine nucleus pulposus cells to determine the least cytotoxic solution. Capitalizing on our CPAs Computed Tomography (CT) contrast enhancement, we imaged and quantified saturation time in intact bovine IVDs under different conditions in a bioreactor. Finally, the entire protocol was tested, including 1 week of frozen storage, to confirm tissue viability in multiple IVD regions after thawing. Results showed cryopreserving medium containing dimethyl sulfoxide and ethylene glycol gave over 7.5 h before cytotoxicity. While non-loaded IVDs required over 3 days to fully saturate, a dynamic loading protocol followed by CPA addition and free-swelling decreased saturation time to <5 h. After cryopreserving IVDs for 1 week with the optimized CPA and permeation method, all IVD regions had 85% cell viability, not significantly different from fresh unfrozen controls. This study created a novel solution to a roadblock in IVD research and development. Using post-compression swelling CPA can be delivered to an intact IVD over 20× more quickly than previous methods, enabling cryopreservation of the IVD with no detectable loss in cell viability.

Force-displacement relation for lumped plasticity model of compact square concrete-filled steel tube columns

Integration of steel and concrete benefits in square concrete-filled tube columns (SCFTs) makes them be utilized extensively worldwide. To evaluate the seismic behavior of special moment frames having SCFT columns, an accurate macro-modeling tool with little complexity is necessary. Although the fiber section can consider both linear and nonlinear behavior of SCFT, it fails to allow for deterioration, which is vital in assessing a seismic resisting system. This study proposes a new deterioration tool based on the Ibarra-Krawinkler model for compact SCFT columns using artificial neural networks (ANNs) through numerical simulation. Initially, 96 specimens with variations in geometry, material, and axial loading conditions were simulated in ABAQUS and then were analyzed using displacement control loading protocol to obtain hysteretic curves, which were used to prepare the data sets for training, testing, and validating the neural networks. Finally, the performance of ANN models was evaluated by statistical relations such as regression and mean square error. Through FEMA 356 and Ibarra-Krawinkler approaches, parameters defining linear and nonlinear phases of SCFTs behavior were derived. By employing efficiently trained neural networks, equations predicting the parameters of the deterioration model were established, and the obtained results show the accuracy and efficiency of the proposed model.

Influence of the Geometric Properties, the Timber–Concrete Interface, and the Load Protocol on the Mechanical Properties of Timber–Concrete Composite Connections

Influence of the Geometric Properties, the Timber–Concrete Interface, and the Load Protocol on the Mechanical Properties of Timber–Concrete Composite Connections

Experimental implementation of the nonstructural element simulator on shake table (NEST) for an archetype tall building

AbstractNonstructural damage, usually predominates in buildings subjected to low to moderate seismic intensities and contributes significantly to business interruption and economic losses. It promotes a rapidly growing need for experimental research and qualification of various types of nonstructural elements in buildings in the recent decades. To provide a novel option of experimentally simulating the realistic boundary conditions for various nonstructural elements in labs, we developed the Nonstructural Element Simulator on Shake Table (NEST), a passively controlled three‐layer substructural testbed driven by existing shake tables. This paper presents the first experimental implementation of NEST on a challenging 42‐story archetype tall building. The dynamic properties of the substructure were tuned to adapt the archetype building and the required shake table motions were solved as a reverse problem by an open‐loop control algorithm. The test results proved the capability of NEST to replicate the history responses of the target floors in the archetype building under either recorded earthquake ground motion or artificial loading protocols for qualification purposes. In all cases, the synthetic relative error in the floor accelerations and the inter‐story drift within the frequency range of interest was less than 5% in the numerical domain and less than 30% in the physical realization. The seismic responses of a variety of nonstructural elements to the substructural motions show that, in the mid‐story of the archetype tall building, the ceiling sustained minimum damage because of the small floor acceleration while the indoor contents slid significantly and even overturned.

Kinetics and Kinematics of the Push Press, Push Jerk, and Split Jerk.

Abstract Soriano, MA, Jiménez-Ormeño, E, Lake, JP, McMahon, JJ, Gallo-Salazar, C, Mundy, P, and Comfort, P. Kinetics and kinematics of the push press, push jerk, and split jerk. J Strength Cond Res 38(8): 1359–1365, 2024—The aim of this study was to explore the kinetics and kinematics across incremental loads with the push press (PP), push jerk (PJ), and split jerk (SJ). Eighteen resistance-trained men performed the 1 repetition maximum (1RM) tests (visit 1) 3–7 days before an incremental loading protocol (60, 75, and 90% 1RM) of the 3 exercises (visit 2). Kinetics and kinematics were derived from force-time data and compared using a repeated-measures analysis of variance with load and exercise as within-subject factors. Dependent variables for the biomechanics assessment were categorized as output (power and impulse), driver (force and work), and strategy (displacement and duration) metrics. The interrepetition reliability was assessed using the intraclass correlation coefficient and coefficient of variation. The PP, PJ, and SJ 1RM performance were 89.7 ± 15.4, 95.6 ± 14.4, and 103.0 ± 16.9 kg, respectively. Driver, strategy, and outcome metrics displayed moderate-to-excellent (intraclass correlation coefficient: 0.58–0.98) reliability with acceptable variability (% coefficient of variation: 2.02–10.00). Increased load resulted in significantly large increases in force, work, displacement, duration, power, and impulse (p &lt; 0.001, = 0.534–0.903). Exercise selection had a significant and large effect on power, impulse, work, and force (p &lt; 0.016, = 0.387–0.534). There was a significant and large effect of load × exercise interaction on work, displacement, and duration (p &lt; 0.019, = 0.158–0.220). Practitioners are encouraged to use heavier loads (90 &gt; 75 &gt; 60% 1RM) during the SJ exercise to maximize output, driver, and strategy kinetics and kinematics.

Unicortical Button Fixation Provide Higher Strength Compared with Transosseous Repair for Subscapularis Tendon in Total Shoulder Arthroplasty

Subscapularis tendon (SSc) dysfunction following total shoulder arthroplasty (TSA) results in poor functional outcomes. There have been numerous SSc repair constructs tested biomechanically and clinically, however, none has been demonstrated as superior. Newer techniques and implants have emerged, but have not been fully tested. We hypothesized that the unicortical button (UB) fixation will provide significantly improved restoration of the anatomic footprint and biomechanical properties when compared to transosseous (TO) repair of the SSc. A digital footprint of SSc humeral insertion was obtained in 6 pairs of fresh-frozen cadaveric shoulders using a three-dimensional (3-D) digitizer. A complete SSc tear was created, and each pair of shoulders was randomized to either SSc repair with UB or TO repair. Each specimen underwent a cyclic loading protocol followed by pull-to-failure. The failure load, elongation at failure, gapping failure, number of cycles until failure, the load at key gapping points (1 mm, 3 mm, 5 mm, and 10 mm) and the failure mode were recorded using high-resolution video recording. 3-D surfaces of the insertion footprint and repair site were obtained, and surface areas were calculated using a custom MATLAB script and laser scanner. Paired t-tests were conducted to compare differences between two repair groups. Failure load was significantly higher in the UB group (382.4 N ± 56.5 N) than in the TO group (253.6 N ± 103.4 N, p=0.005). TO repair provided higher gapping at failure (28.8 mm ± 8.2 mm) than UB repair (10.4 mm ± 6.8 mm, p=0.0017). UB repair had significantly higher load at the 1-mm, 5-mm, and 10-mm gapping compared with TO repair with p=0.042, p=0.033, and p=0.0076, respectively. There were no significant differences between elongation failure, the difference in footprint area from native to repair states, or the percentage of restored footprint area between groups. (p=0.26, p=0.18 and p=0.21 respectively) CONCLUSION: The UB fixation showed a significantly lower gap at failure, higher failure load and number of cycles until failure, and higher gap loads compared with the traditional TO repair for SSc. Although more clinical research is necessary, the UB fixation that utilizes cortical bone presents promising results.

A review on cutting-edge innovations in dental implantology

Dental implantology has advanced significantly with innovations in materials, designs, surgical techniques, and digital technology aimed at enhancing patient outcomes. Applications span specialties like prosthodontics, periodontics, orthodontics, oral surgery, aesthetic dentistry, and pediatric dentistry, with pediatric implants showing a success rate of 90-95% over ten years. 4D printing is emerging as a transformative technology for dynamic implants. This review traces the historical development from ancient attempts to modern titanium-based designs, emphasizing milestones like osseo-integration discovery by Dr. Per-Ingvar Brånemark. Recent progress includes enhanced titanium surfaces, biocompatible zirconia, and composite materials, as well as innovations in implant design such as nanotechnology-enhanced surfaces and personalized implants, all aimed at improving osseointegration and stability, while surgical approaches now prioritize minimally invasive techniques, immediate loading protocols, and computer-guided procedures to minimize patient discomfort and expedite recovery was discussed.

Mandibular overdenture retained by four one-piece titanium-zirconium mini implants: A 2-year RCT on patient-reported outcomes

AimThe positive impact of implant interventions on dental patient-reported outcomes is an essential parameter of treatment effectiveness. This study assessed the 2-year changes in patient satisfaction and oral health-related quality of life (OHRQoL) of edentulous patients treated with a four mini implant mandibular overdenture (IOD) MethodsThe study was planned as a 2 × 2 factorial randomized clinical trial that tested two surgical approaches (flapped or flapless) and two loading protocols (immediate and delayed) using a titanium-zirconium mini implant (Straumann Mini Implant System®) and a PEEK retentive system (Straumann® Optiloc® Retentive System). Outcome measures (OHIP-Edent scores and the McGill Denture Satisfaction questionnaire) were assessed before treatment and at the 3-, 6-, 12-, and 24-month follow-ups. The Friedman test and multiple regression using Generalized Estimating Equations (GEE) were used for data analysis, considering the per-protocol (PP) and intention-to-treat (ITT) approaches ResultsSeventy-four patients were randomized to the study groups. No implant failure occurred during the study period. Marked improvement in all post-treatment periods compared to baseline were observed for the two outcomes. No significant effect of patient's gender, age, and surgical protocol on the study outcomes. The effect of treatment provision was significant for the two outcomes in the PP and ITT approaches (p < 0.001). A barely significant positive effect of the immediate loading was observed for OHIP-Edent in the PP approach (p = 0.020) ConclusionIOD treatment significantly improved patient-reported outcomes measures, with sustained benefits over the two years of overdenture use, and can be considered a promising treatment option in for the edentulous mandible.