The effects of Hevea bransiliensis natural rubber on phospholipid concentrations of experimental rats were analyzed. Forty albino wister rats of either sex weighing 140-450g were used. The rats were divided into five equal groups marked A, B, C, D and E of eight rats each, and each group was fed on different dietary regime A, B, C, D and E respectively as indicated in tables 1 and 2. Diet A, (the control) had no rubber seed oil in the diet, whereas diets B, C, D and E (the experimental) had 2% refined rubber seed oil, 2% crude rubber seed oil, 4% refined rubber seed oil and 4% crude rubber seed oil by weight incorporated respectively. The results showed an increase in plasma phosphatide level for groups B and A rats. Little increase in plasma phosphatide levels were found in groups D, C and E rats. The results of liver phospholipids showed an increase in phospholipids concentration of groups C, D and E rats compared to groups B and A (control) for the corresponding weeks. Keywords: Hevea bransiliensis, Natural rubber, Phospholipids concentration and Diets.