Literature Recommendations Research Articles

Ibero-American consensus statement on migraine treatment.

INTRODUCTION AND OBJECTIVES.Migraine is the most common reason for neurology outpatient consultation; more than 80% of patients with migraine suffer some degree of associated disability. Migraine is an underdiagnosed disorder and patients frequently receive inappropriate treatment, which is why it is necessary to establish recommendations to improve patient management. The objective of this document is to establish a consensus position on the pharmacological treatment of migraine, including general measures and detailed analysis of the different options for the treatment of attacks and their prevention, from the perspective of Ibero-American countries. METHODS AND RESULTS.Based on the recommendation documents published by the scientific societies of different Ibero-American countries, 2 surveys were prepared; through the application of the Delphi methodology and discussions in subsequent meetings, a document was developed in consensus format, supported by evidence from the literature and expert recommendations. ConclusionsA series of recommendations were agreed upon for the treatment of episodic migraine and chronic migraine, both for the acute management of attacks and for their prevention. These recommendations are based on the consensus process and a literature review, and are adapted to the regional conditions of the Ibero-American countries.

Lower Extremity Osseointegration Postoperative Rehabilitation Protocols: A Scoping Review.

Lower-extremity transcutaneous osseointegration is a rehabilitation alternative to socket-suspended prostheses. The rehabilitation process, philosophies, and routines remain under-described. This review, primarily, identifies commonalities and differences among protocols. Secondarily, strategies are proposed to streamline future research of post-osseointegration surgery rehabilitation. Two differently phrased queries of Google Scholar, Pubmed, Embase, and Web of Science were performed. First using either "osseointegration" or "osseointegrated" or "bone anchored prosthesis" AND [last name]. Second, replacing author name with "physical therapy" or "rehabilitation." Six hundred eighty-eight articles were identified describing lower-extremity rehabilitation following osseointegration. Following software-based deduplication, manual abstract and full-text review, article reference evaluation, and use of Google Scholar's "Cited by" feature, 35 studies were fully analyzed. First, a consolidated summary was made of protocols focusing on stages, timing, and other descriptions of postoperative rehabilitation. Subsequently, strengths and limitations of protocols were considered to propose potential strategies to investigate and optimize postoperative rehabilitation. All articles describe rehabilitation having this same order of goal progression: from surgery to gradual weight bearing and final goal of independent ambulation. The most impactful difference influencing the stated final goal of independent ambulation was whether 1 or 2 surgical stages were performed. No articles reported patient success rate achieving proposed goals and timing, or challenges during rehabilitation. Therefore, the first research suggestion is to investigate actual success rates achieving proposed goals and timing. Second, to further explore rehabilitation of performance deficits, beyond unaided ambulation. Finally, to incorporate technology such as mobility trackers to more objectively understand prosthesis use and mobility. All lower-extremity osseointegration rehabilitation literature recommends identical goal progression order. No studies evaluate patient challenges or variation. Understanding and addressing such challenges may enhance postoperative rehabilitation. This article consolidates published rehabilitation protocols post-osseointegration surgery. Specific analysis and experimentation of the protocols may enhance the uniformity and potential of patient rehabilitation.

Automatic Processing of Bibliometric Data: Newest Literature Analysis Algorithms

Automated processing of bibliometric data has become an integral element in understanding and measuring the impact of scientific research as well as trends in the academic literature. The purpose of this study was to evaluate and compare current literature analysis algorithms to identify advances in automated processing of bibliometric data. This study explores the use of the latest algorithms in literature analysis which includes identification of research themes, research network analysis, citation impact evaluation, and development of literature recommendation algorithms. This research exposes innovative applications that utilize the latest technologies in text processing and data analysis to assist researchers, libraries, and information professionals in revealing deep insights from the latest scientific literature. The results of this study illustrate that the automated processing of bibliometric data with the latest algorithms paves the way for a deeper understanding of the development of scientific research, its impact in the scientific community as well as improving bibliometric analysis methods and tools by integrating the latest algorithms, so that scientific research and trends can be identified more accurately and relevantly. The study could use more sophisticated multifaceted techniques to analyze simple productivity measures based on article citations. This research is also able to recognize and describe the development of new science and technology.

Integrated assessment of simultaneous threshold exceedance of heat, air pollution and airborne allergenic pollen across Europe

BackgroundClimate change is expected to elevate exposure to several environmental health risk factors, including extreme environmental temperatures, air pollution and airborne allergenic pollen. Given their interconnected effects on respiratory and cardiovascular diseases, it is crucial to evaluate these exposures simultaneously. Yet, comprehensive efforts to do so remain limited. This research aims to develop an approach using modelled data, in conjunction with health-based threshold values, to assess whether, where and when there is simultaneous threshold exceedance of heat, air pollution and airborne allergenic pollen in Europe. MethodsHourly exposure data for the three stressors were sourced from three models (air pollution: LOTOS-EUROS, pollen: Copernicus Atmosphere Monitoring Service, meteorological conditions: ECMWF) for 2021 and 2022. Thresholds for each stressor that indicate the boundary of acceptable limits were based on officially established tresholds or literature recommendations. The result is a 0.1°x0.1° resolution grid (approximately 10 km x 10 km) for each stressor, with each cell representing whether exposure met or exceeded the threshold. FindingsSimultaneous threshold exceedance of air pollution and heat is occurring in various degrees throughout Europe. In the summer of 2022, the exceedances ranged from below 1% in large parts of Northern Europe to as much as 25% of the time in the Mediterranean area. An assessment of monthly threshold exceedance patterns shows a dynamic and changing co-exposure pattern across the year, which differs per region. InterpretationThis work lays out a robust approach to assess simultaneous threshold exceedances of multiple environmental health risk stressors. This approach can guide policy makers in pinpointing high-risk areas particularly vulnerable to simultaneous threshold exceedances, and develop mitigation strategies for those areas. FundingInternal funding from TNO.

Современные принципы и методы оказания первой помощи при утоплении

Summary. The aim of the study — to review and analyze the scientific literature and current recommendations on first aid (FA) for drowning; based on the results of the analysis, to develop a draft universal algorithm for providing FA in drowning. Study materials and methods. The material for the study comprised international and national guidelines on FA in drowning and articles on the topic of FA in drowning published in peer-reviewed scientific journals. The information search was carried out in January 2024 using the Google search engine and bibliographic databases Google Scholar, PubMed, and eLIBRARY.RU. Results of the study and their analysis. Being one of the most common causes of accidental death, drowning is a serious public health problem. Timely and correct provision of FA by incident witnesses significantly reduces the risk of death and disability for the victims. At the same time, the topic of providing FA for drowning has been little touched upon in the domestic scientific literature. There are no uniform guidelines for the Russian Federation on the provision of FA in drowning. Improvement of the organizational basis in Russia for effective provision of FA for drowning requires the development and approval of a unified formal procedure for providing FA for drowning and the establishment of the practice of mass training of the population in modern principles and methods of providing FA for drowning. Based on the results of the analysis of current international guidelines on FA, the proposed universal algorithm for providing FA for drowning, after discussion and agreement by the scientific community, may act as a basic element for creating the formal procedure for providing FA and developing appropriate educational and awareness-raising materials on FA for drowning.

Identification and Analysis of Key Factors Affecting Digital Transformation of Small and Medium-Sized Manufacturing Enterprises

The digital transformation of small and medium-sized manufacturing enterprises is influenced by various factors, and the relationship between them is not yet clear. Studying the factors that affect the digital transformation of small and medium-sized enterprises can promote the digital transformation process of small and medium-sized manufacturing enterprises. On the basis of summarizing literature and expert recommendations, this study identified the influencing factors in the digital transformation process of small and medium-sized manufacturing enterprises, and analyzed the key influencing factors using a combined method of DEMATEL-ISM-MICMAC (Decision-Making Test and Evaluation Laboratory-Interpretive Structural Model-Matrices Impacts Croises-Multiplication Appliance Classement). Research has found that digital policies, market demand, business model innovation, third-party data-driven services, and the digital foundation of enterprises are key factors in the process of digital transformation. In addition, the causal factors in the DEMATEL method, the essential factors in the ISM method analysis, and the independent factors in the MICMAC technique analysis can mutually support and complement each other. This study enriches the methodology for studying the factors of digital transformation and provides reference for the digital transformation of small and medium-sized manufacturing enterprises and government policy formulation.

Higher doses of fluconazole are needed to ensure target attainment in critically ill adults on continuous Veno-venous hemodialysis

BackgroundCritically ill patients undergoing Continuous Renal Replacement Therapy (CRRT) are treated with higher doses of fluconazole based on the literature recommendations. However, clinical follow-up data demonstrating the effectiveness of this approach are lacking. PurposeA retrospective cohort study was conducted to evaluate whether target attainment was achieved with higher doses of fluconazole. Additionally, the study focused on identifying factors that may contribute to variability in fluconazole exposure in these patients. MethodsCritically ill patients undergoing Continuous Veno-Venous Hemodialysis (CVVHD) who received either standard or higher doses of intravenous fluconazole were included. Evaluation of target attainment was conducted for each dose regimen. ResultsAdministering higher doses resulted in target attainment in 100 % of the patients, indicating that starting with at least 400 mg twice daily is an adequate dosing guideline. In this study, only the dose of fluconazole was found to significantly influence target attainment (p < 0.001), with no other predefined factors identified as having a significant impact. ConclusionAccording to the results of the study, increasing the fluconazole dose to at least 400 mg twice daily is sufficient to reach the desired target in critically ill patients undergoing CVVHD.

A Tossed Salad: Heterogeneity of Societal Culture and Preferred Leader Behavior in the Russian Federation

In this study, we examine societal-cultural values and employee preferences for explicit leader behaviors and their relationships in the Russian Federation. Our analyses of data obtained from samples in two large regions (Siberia and Western Russia); indicate the heterogeneity, that is, differences of the traditional, Slavophile-Orthodox, and Western-like characteristics therein. In doing so, we contribute to the literature on culturally contingent business leadership in Russia, by providing a basis for and stimulating research to enlarge and systematize the literature and construct useful practical recommendations.

Liposomal Bupivacaine in Managing Postoperative Pain Following Shoulder Surgery

To optimize postoperative analgesia following shoulder surgery, current literature recommends multimodal approaches, including the use of regional liposomal bupivacaine (LB), a long-acting local anesthetic. The liposomal formulation of bupivacaine affords it a longer duration of action without a substantial peak plasma concentration; this combined with 3% free bupivacaine provides patients with substantial, prolonged postoperative analgesia following shoulder surgery. The use of LB as part of a multimodal approach to postoperative pain results in diminished use of opioids, reduced pain, and decreased length of hospitalization. Current literature supports these effects following a wide variety of shoulder procedures; however, some studies describe no benefit and list drawbacks including higher costs when electing to use LB instead of comparable, more affordable treatment modalities. In the interest of reducing the number of opioid prescriptions following orthopedic procedures, it is imperative to continue investigating the efficacy of LB as an opioid-sparing pain reducer. Recent literature suggests certain patient populations may be less suitable for implementing this treatment modality; namely those with a history of opioid use, prior surgeries, substantial systemic illness, and existing cardiopulmonary compromise. Patient demographics may be an additional consideration when determining the potential utility of LB to optimize analgesia after shoulder surgery.

Recovery Supplementation Strategies Applied to Elite Soccer Players

Purpose of review: During soccer seasons, athletes have canned a 48 number of matches. Therefore, recovery supplementation strategies that optimize recovery and/or reduce the damage caused by the number of matches during a season are important to help elite football players in their state of recovery. This way, the purpose of this review is to provide a holistic view of the mainly recovery supplements and their effects on elite soccer players recovery, based on what the literature recommends decreasing the oxidative stress, muscle damage and help them in the status recovery. Recent findings: Vitamin C e vitamin E in co-administration (500 mg vitamin C with 1200 IU vitamin E per day), 6 g per day of glutamine supplementation, and 60 mL drinks per day of Turmeric Original Shot (1400 mg curcumin combined with 10 mg of piperine), were able to decrease oxidative stress and lower rates of injury. 1000 mg magnesium citrate twice a day and 5000 IU (international units) cholecalciferol supplement daily were improving the recovery status. Coenzyme Q10 100 mg twice daily and omega 3 (550 mg DHA and 550 mg EPA) proven a reduction in the levels of the muscle-damage marker. Summary: Recovery supplements should include the vitamin's C, E, and D, besides that glutamine, magnesium, and turmeric with piperine to be able supplements to help the elite soccer players recovery, decreasing oxidative stress and rates of injury.

Development and implementation of just-in-time curricula for on-shift teaching during times of boarding.

Overcrowded emergency departments (EDs) due to boarding of inpatients can lead to fewer patients seen by residents and may negatively impact their education. The existing literature recommends providing educational resource banks to augment teaching during overcrowding. We aimed to develop and evaluate the use of an educational curriculum during times of boarding. Using Kern's model of curriculum development, we conducted local and national needs assessments to identify existing curricula. The final curriculum consisted of electrocardiogram (ECG) cases, procedural resources, journal articles, and oral boards style cases. The derived curriculum was implemented at the study site, where content was released weekly via email or Slack and via our departmental educational blog. Residents were asked to fill out a survey assessing their satisfaction with the resource, their current patient load, and current National Emergency Department Overcrowding Study score (NEDOCS). We compared clinician educator satisfaction with teaching before implementation and at 3 months after implementation using Wilcoxon rank-sum test. The national needs assessment was sent to the Council of Residency Directors (CORD) listserv. There were 36 unique program responses with only one program with resources for teaching during overcrowding. The derived curriculum was used seven times during the study period. The mean (±SD) NEDOCS at the time of resource use was 238.7 (±23.6). The median (range) number of active patients while using the resource was 4 (0-7). ECG cases were the most used resource. Mean (±SD) satisfaction with teaching before implementation was 2.8 (±0.9; Likert-type item scale 1 to 6 from not at all to a great deal satisfied). Satisfaction with teaching improved after implementation of the curriculum, with the mean (±SD) increasing to 3.5 (±1.0; p = 0.01). We report the development and implementation of a local educational curriculum for use during times of boarding. The curriculum was lightly used during the study period, but the availability of a curriculum may have increased satisfaction with teaching during boarding.

Stability of Hemostasis Parameters in Whole Blood, Plasma, and Frozen Plasma: Literature Review and Recommendations of the SFTH (French Society of Thrombosis and Haemostasis).

Preanalytical sample management is critical for a proper assessment of hemostasis parameters, and may differ depending on prescribed tests or additional tests considered to be necessary after initial results. Although there is quite vast literature on this issue, the Working Group of the French Society of Thrombosis and Haemostasis (SFTH) deemed it necessary to make an in-depth literature review and propose recommendations for the proper handling of samples prior to hemostasis assays. This extensive assessment is accessible on-line in French at the SFTH website. Here, a more synthetic view of these recommendations is proposed, supported by easy-to-use tables. The latter respectively deal with the stability of whole blood or fresh plasma, frozen samples, and proper handling of samples forwarded on dry ice. Procedures are classified as recommended, acceptable, not conformed and lacking data. This work involved the retrieval of 125 references, first screened by a working group of 6 experts, then reviewed by 20 other experts in the field. The highly detailed conditions summarized in these tables will hopefully help hemostasis laboratories to secure the conditions recommended for sample collection and transportation. Moreover, as some conditions clearly lacked recommendations, this review can open new fields of investigation for hemostasis preanalytics.

The Role of Family and Friends to Broaden and Diversify Participation in Educational Research

This study examined critical factors in a mentoring system within a federally-funded Pathways to the Education Sciences Research Training Program to prepare undergraduates at a Hispanic-serving institution (HSI) for graduate studies in educational research. Our conceptual framework integrates an inclusive model of family engagement consistent with the literature recommendations for diverse families of college students. We considered the following question: what is the role of family and friends within an orchestrated network of mentors who provide support to undergraduate fellows from minoritized groups in their pathways toward graduate studies in educational sciences? We analyzed quantitative and qualitative responses from an end-of-program survey administered to one cohort of this program. Within their mentoring network, fellows reported that family and friends provided important support in socio-emotional, cognitive, and identity development, but not as strong as that provided by distributed faculty and academic mentors. This study furthers our understanding of the role of family and friends within an orchestrated network of mentors within our Pathways Training Program. However, we still need to extend our knowledge of how research training programs at HSIs can be more intentional in emphasizing the important contributions family and friends provide to promote the success of diverse students in their pathways toward graduate studies.

A New Discovery on the Potential Stability of Ion-Selective Membranes: The Poison from Tetrahydrofuran.

Ion-selective electrodes (ISEs) have widespread use in the fields of clinical and environmental analyses. Tetrahydrofuran (THF) is the most used solvent for the preparation of modern ISEs, equipped with ion-selective membranes (ISMs). Until now, the influence of impurities in THF toward potentiometric instability of ion-selective membrane based ISEs was probably associated with the presence of either residual water or peroxide. To address this issue, most literature recommends redistilling THF prior to use in the preparation of the potentiometric membranes. Current study reveals that the actual THF impurity that is responsible for potential instability in the ISM includes products from the oxidation of THF, which contains the hydroxyl group and possibly carbonyl group with a boiling point of above 200 °C. The density functional theory calculation supported pathway of the chemical reaction of THF oxidation, hence, the chemical structure of the uncertain impurities was predicted. The underlying reason for the deteriorating potential stability of the ISEs is proposed as the significant hydrophilicity of these impurities that affect the partitioning of the ion sensing components in the membrane, thus enhancing the leaching of the membrane components from the membrane phase. This finding explains why redistillation of aged THF is advised.

Antimicrobial infusion practices within intensive care units: Carbapenem infusion preparation and administration process errors

ObjectiveTo describe nurse preparation and administration of intermittent carbapenem infusions. Research methodology/designThis observational study documented the carbapenem infusion process to adult patients in three general intensive care units. Main outcome measuresTiming and duration of infusions were observed. Volumetric analysis of infusion items was conducted to determine loss of reconstituted carbapenem during preparation and administration phases. ResultsCarbapenem infusions (n = 223) administered to twenty adult patients were observed. Infusion duration guidance was variable, with two ICUs following current literature recommendations, and one ICU referring to medication package insert information. Within these parameters, only 60 % of infusions complied with infusion duration. Non-compliance with planned time of administration impacted on desired dosing intervals. Incomplete delivery of intended dose was found during: sub-optimal reconstitution of vials, incorrect number of vials reconstituted, failure to administer a dose (missed dose), and discarding antibiotic residue in infusion items. Volumetric analysis of infusion items showed mean dose losses of 4.9 % and 1.2 % in discarded vials and syringes. Mean drug losses of 6.3 % and 30.8 % occurred in discarded infusion bags and infusion lines respectively. No flushing guidance or practice was observed. ConclusionIncorrect nurse administration of antibiotics resulted in varying durations of infusions and the non-delivery of prescribed dose. Under-dosing has the potential to contribute to selection pressure for bacterial antibiotic resistance. The increasing frequency of intravenous delivery of antimicrobial agents through infusions requires an understanding of the required duration of administration and how to manage residual drug remaining in the intravenous line once the infusion is completed. Implications for clinical practiceFlushing of administration lines is not common practice following intermittent antimicrobial infusions. Although there are multi-factorial risk factors for antimicrobial resistance in the critical care arena, nurse infusion practice must ensure that patients receive intended antimicrobial treatment. Attention must be given to the potential for antimicrobial resistance from environmental contamination with the disposal of infusion items containing undelivered antimicrobial medication.

Non-parametric systematic review of the literature and future recommendations on the efficiency of the National Innovation System

non-parametric systematic review of the literature and future recommendations on the efficiency of the National Innovation System

The trend and ripple effects of retractions in primary health care: A bibliometric analysis.

In primary health care, the dissemination of retracted publications through literature reviews, guidelines, and recommendations can have a significant and lasting impact. Despite this potential threat, the retraction consequences and patterns in this domain have not been extensively explored. Therefore, this study investigates the characteristics and ripple effects of retracted papers in primary health care literature. Retracted publications indexed in PubMed from 1984 to 2022 in primary health care journals underwent bibliometric analysis. The dataset included detailed publication information, from which we derived annual retraction rates and examined trends by journal, authorship, and geographic origin. We further evaluated the extent of influence exerted by retracted papers through postretraction citation analysis. In 44 primary health care journals, 13 articles were retracted over the study period, representing a retraction rate of 0.01%-notably lower than the aggregate rate for all PubMed journals. Despite this, we observed a recent surge in retraction frequency, especially in the last decade. The median interval to retraction was 15 months, with scientific misconduct, specifically fabrication, and plagiarism, as the predominant reasons. After retraction, the articles continued to exert considerable influence, averaging 25 citations per article with a 78.1% postretraction citation prevalence. Retractions resulting from scientific misconduct in primary health care are increasing, with a substantial portion of such work continuing to be cited. This trend underscores the urgent need to improve research ethics and develop mechanisms that help primary care physicians discern reliable information, thereby reducing the reliance on compromised literature.

Multicenter survey about leg length discrepancy and total hip arthroplasty: postoperative management.

We created a Multicenter Survey for Italian orthopedics surgeons on how they approach leg length discrepancy when dealing with primary total hip arthroplasty. Aim of the study was to show how surgeons manage LLD and follow literature recommendations during clinical practice. The Survey was composed of 25 questions divided in 4 sections: surgeon's profile, preoperative and intraoperative evaluation, postoperative management. In this paper, we report the absolute and relative frequencies of answers to section on "postoperative management." Then, regarding the treatment of residual LLD, we reported whether trauma surgeons and experts in replacement surgery had higher odds ratios for providing "literature-based" answers compared to orthopedics physicians. Only four questions received more than 70% agreement on one of the answers. The OR for giving the "literature-based" answer, taking OP as the reference group was 1.57 for TR and 1.72 for RS for 10mm LLD at first follow-up (FU) and 1.23 TR and 1.32 RS when 20mm. When 10mm LLD at 3months FU the OR was 0.88 TR and 1.15 RS. The OR for treatment of LLD after the first examination of a new patient was 2.16 TR and 1.85 RS. LLD is a debated topic with no definitive recommendations. Many decisions still depend on tradition. Treatment of LLD during clinical practice often differs from literature recommendations.

Tracing Inclusive Leadership: A Systematic Literature Review and Recommendations for Future Research

Tracing Inclusive Leadership: A Systematic Literature Review and Recommendations for Future Research

Customized Integrated Management for Non-Insulin Dependent Diabetes Mellitus (NIDDM) and its Complications: Literature Review and Recommendations for the Future Policy Decisions

Customized Integrated Management for Non-Insulin Dependent Diabetes Mellitus (NIDDM) and its Complications: Literature Review and Recommendations for the Future Policy Decisions