A study has been carried out to obtain the solutions for heat and mass transfer from natural convection flow along a vertical surface with temperature-dependent fluid viscosity embedded in a porous medium due to thermal-diffusion (Soret) and diffusion-thermo (Dufour) effects. This paper concerns with a steady two-dimensional flow of incompressible fluid over a vertical stretching sheet. The fluid viscosity is assumed to vary as a linear function of temperature. A scaling group of transformations is applied to the governing equations. The impact of thermophoresis particle deposition with chemical reaction in the presence of thermal-diffusion and diffusion-thermo effects plays an important role on the temperature and concentration boundary layer. The results thus obtained are presented graphically and discussed.