Objectives. Findings from previous studies implied that appropriately controlling load knowledge might help improve the biomechanical performance during lifting tasks. However, only load weight knowledge was often discussed in previous studies. The current study aimed to complement the existing studies and provide improved knowledge about the influence of load knowledge on lifting biomechanics. Methods. Twenty-four healthy male participants were recruited and instructed to perform symmetric lifting tasks with different load weights under different load knowledge conditions. Load weights were set at three levels (40, 80 and 120%) of each participant’s maximum acceptable lifting capacity. The examined load knowledge conditions included ‘no knowledge’ condition, ‘weight known’ condition, ‘fragile material known’ condition and ‘weight and fragile material known’ condition. Results. We found that when knowing fragility information about lifting materials, workers tended to be more cautious by adopting a less dynamic motion pattern during the landing phase, as evidenced by decreases of 6–8% in elbow joint acceleration. The ‘cautious’ lifting pattern when fragility load knowledge was presented could contribute to reduced risk of lower back disorder. Conclusion. This finding could help to develop lower back disorder prevention interventions to improve occupational safety and health.