Background and Objectives: Diabetes mellitus has become representing one of the most challenging publichealth problems of the 21st century. It is a metabolic disease characterized by high blood glucose levels(hyperglycemia) which may arise from defects in the secretion of insulin, defects in insulin action, or both.Diabetic patients suffering from worse quality of life in rural and urban area. Aims of the study were toassess quality of life Type-2- of diabetic patients in rural and urban area , to identify the relationshipbetween some characteristics of diabetic patients and quality of life and comparison of quality of life ofdiabetic patients between urban and rural area in Kirkuk city.Material and Method: The non- experimental approach and descriptive design was used in this study . Thestudy was conducted at Azadi Teaching Hospital in Kirkuk city and Al-Hawija General Hospital at Al-Hawija district during the period from 15th November 2012 to the 20th of June 2013 .Purposive sampleconsists of (110) clients from urban area who visited Azadi Teaching Hospital and (110) clients from ruralarea who visited Al-Hawija General Hospital . In order to collect the study information, a questionnaire wasconstructed depending on the criteria of World Health Organization scale (WHO ) format that modified byresearcher and related literature. It composed of two parts , part one included ( 5 ) items which focused onthe client demographic characteristics such as (age, gender, marital status, residence , occupation , level ofeducation .Diabetes Mellitus Quality of life questionnaire is the instrument that consists of (5) domains. Thedomains are Independence , daily physical activities , Psycho-social , beliefs , environmental andcircumstances. The overall questions includes (80 ) items. The questions were rated on (3) point- likertscale. The score ranges between (0-240), never ( 1), sometimes (2), always (3).content validity wasdetermined by presenting the questionnaire to a panel of (10 ) experts.Results: The data analysis shows that most of the type -2- diabetic patients were male in urban and ruralarea and constituted (75.3% ) and ( 61.8 % ) respectively . In relation to the age , high percentage of thesample were between age (55-64 ) years in urban and rural area and constituted (32.7% ) and (34.5 % )respectively .Also the data analysis showed that there is a significant statistical association between healthrelated quality of life (HRQoL) items that are related to independency, daily physical activities, psychosocialaspects ,beliefs and environmental circumstances. Also the study concluded that health problems ofdiabetic patients related to quality of life differs in sub domains have mild effects on the quality of life ofpatients with diabetic in rural than urban area .Conclusions: The socio demographic characteristic of quality of life of type 2- diabetic clients (age,gender, marital status, level of education, jobs ) are different in effects on independency, daily physicalactivities, psycho-social aspects, beliefs and environment Quality of life of diabetic patients type -2- moreimpact in rural than urban area.Key words: Quality of Life, Diabetic Patients Type -2-, Urban, Rural