Library Of Dissertations Research Articles

Research on the use and creation of paradidactic books for teaching statistics in elementary school in Brazil

The objective of this work was to systematically analyze the literature in Brazil, through scientific articles, books or book chapters, monographs and dissertations, and stricto sensu graduate theses, who used or created paradidactic books for teaching statistics in elementary school. The databases searched were: the Brazilian Digital Library of Theses and Dissertations (BDTD), Theses and Dissertations Catalog of the Coordination for the Improvement of Higher Education Personnel (CAPES) and Academic Google, based on the keyword system, Book Didactics as a first option (E) Statistics (E) Elementary School (E) Education. Thirteen studies were considered as results, in the period from 2002 to 2021, and the IRaMuTeQ software was used for the multidimensional analysis from the organization in texts (corpus), each one being defined as “text segment”. Each text was prepared considering what was emphasized in the research, the methodology or methodological approach used, the context in which it was developed, and the types of study and areas involved and the main results and conclusions. In addition, data analysis was organized, based on the identification for each of the texts, of the following variables of interest: type of publication (pubType); year of publication of the text (yearPub); target audience for the work (publicTeaching); and the Brazilian region where the work was carried out (PubRegion). The research is aimed at students and teachers in the early and late years of elementary school and developed in graduate programs and their respective research groups. We emphasize that research on the use and creation of textbooks for teaching statistics in elementary school is still incipient, highlighting the need for more research, but it can be seen that there is the development of new research at the PhD level. In addition, a trend is indicated in the relationships with experiential knowledge and with everyday life, contributing to the formation of citizens aware of the development of statistics.

Reporting guidelines for surgical technique could be improved: a scoping review and a call for action

ObjectivesTo identify reporting guidelines related to surgical technique and propose recommendations for areas that require improvement. Study Design and SettingA protocol-guided scoping review was conducted. A literature search of MEDLINE, the EQUATOR Network Library, Google Scholar, and Networked Digital Library of Theses and Dissertations was conducted to identify surgical technique reporting guidelines published up to December 31, 2021. ResultsWe finally included 55 surgical technique reporting guidelines, vascular surgery (n = 18, 32.7%) was the most common among the clinical specialties covered. The included guidelines generally showed a low degree of international and multidisciplinary cooperation. Few guidelines provided a detailed development process (n = 14, 25.5%), conducted a systematic literature review (n = 13, 23.6%), used the Delphi method (n = 4, 7.3%), or described post-publication strategy (n = 6, 10.9%). The vast majority guidelines focused on the reporting of intraoperative period (n = 50, 90.9%). However, of the guidelines requiring detailed descriptions of surgical technique methodology (n = 43, 78.2%), most failed to provide guidance on what constitutes an adequate description. ConclusionOur study demonstrates significant deficiencies in the development methodology and practicality of reporting guidelines for surgical technique. A standardized reporting guideline that is developed rigorously and focuses on details of surgical technique may serve as a necessary impetus for change.

Analysis of right-to-health litigation involving high-cost medicines in Brazil: a scoping review protocol

Many studies investigating right to health litigation involving medicines mention “high-cost medicines”. However, detailed data on the characteristics of legal claims for these drugs and their share in terms of volume and spending in right to health litigation involving medicines is scarce. This paper presents a protocol for a scoping review that seeks to determine the profile of legal claims for high-cost medicines in Brazil and calculate the volume of purchases and amount spent on these drugs as a share of overall volume and spending related to right to health litigation involving medicines. Structured following the PRISMA-P checklist, this protocol describes the stages of the methodological framework for conducting the review. Guided by the PCC mnemonic (Population, Concept and Context), we searched for articles and other academic research reports published from 2000 to the present date using the MEDLINE, Embase, LILACS, Scopus, and Web of Science databases and the Brazilian Digital Library of Theses and Dissertations, respectively. Study selection will be performed in two stages (reading of titles and abstracts and assessment of the full-text version of the articles) by two independent reviewers. Any disagreements will be resolved by a third reviewer. We will perform a qualitative and quantitative analysis of the results, which will be presented in a descriptive format using figures, tables, and diagrams. The final review report will follow the Preferred Reporting Items for Systematic Reviews and Meta-Analysis for Scoping Reviews (PRISMA-ScR) checklist. This protocol is registered with the Open Science Framework (DOI: 10.17605/OSF.IO/8PXUB).

The effectiveness of compassion-based interventions among cancer patients: A systematic review and meta-analysis.

This study examined the effects of compassion-based intervention on mental health in cancer patients by using systematic review and meta-analysis of randomized controlled trials (RCTs). Eleven bibliographic databases were searched from their earliest data available date up to March 1, 2022. The databases were PubMed, CINAHL, MEDLINE, PsycINFO, WOS, Cochrane, Embase, Scopus, ProQuest Dissertations, Airiti Library, and the National Digital Library of Theses and Dissertations in Taiwan. Ten studies from 2015 to 2021 were included with a total of 771 cancer patients. Most were targeted at women with breast cancer. Brief compassion-based interventions of approximately 30minutes were conducted by audio file, paper, and web-based self-guided writing prompts. Most were conducted after the completion of active treatment. Anxiety was the most measured outcome. Constructive compassion-based interventions with 4- to 12-week sessions were conducted by a trained facilitator. Most were conducted for patients who had undergone treatment, and depression was the most measured outcome. The meta-analysis indicated that compassion-based interventions had a significant effect of reducing depression and increasing self-compassion. Moderation analysis indicated that constructive intervention showed more benefits of increased self-compassion than brief intervention. Both face-to-face and non-face-to-face web-delivered formats had benefits for increasing self-compassion compared with the control condition. Compassion-based interventions might provide an effective strategy for improving self-compassion and depression among patients with breast cancer. Suggestions for further research and health-care providers follow.

Saúde do adolescente na rede federal de ensino brasileira: uma metassíntese

ABSTRACT The institutions of the federal educational network have their own health team and, therefore, have the possibility of developing multiple strategies for the implementation of School Health Program actions. This study aimed to systematize and synthesize the scientific production developed by workers from the federal educational network on adolescent health in the school environment. This is a qualitative meta-synthesis carried out from searches on the Virtual Health Library, Brazilian Digital Library of Theses and Dissertations, and Google. Content analysis was used for data analysis. The sample consisted of 15 publications and 4 thematic units emerged: pedagogical integration of health education in federal institutes; conception of adolescence and adolescent health in the school environment in federal institutes; perspectives of health work in federal institutes with adolescents; and facilities and difficulties in the development of adolescent health in the school environment in federal institutes. It was found that the scientific production on the subject is still incipient. Even in federal institutes, it is necessary to advance in the methodology of activities and in the topics of health education developed. It is necessary to stimulate youth protagonism, transcending the hygienist and fragmented aspects of school health.

The role of the supervising teacher in the curricular internship: what do publications say?

The Curricular Internship (CI) has become an opportunity for research, reflective analysis, observation, and re-signification of the teaching profession. In this sense, the present article is aimed at assessing the publications that address this theme. Thus, we chose to develop this study in the area of teacher education, based on the assumption that the CI can favour the acquisition of knowledge required for the teaching activity and, consequently, the teacher’s professional development. We adopted the bibliographic analysis of scientific papers from 2015 to 2020, retrieved from the Journal of the Coordination for the Improvement of Higher Education Personnel’s Portal (CAPES), Google Scholar, Brazilian Digital Library of Theses and Dissertations (BDTD), Repository of the Graduate Program in Education of the State University of Ceará (PPGE/UECE), and the Education Resources Information Center (ERIC). The analyses pointed out the internship as a moment of articulation between theory and practice, and of knowledge constitution, particularly the knowledge gained through experience. Likewise, they indicated the need for greater articulation between university and school, and some emphasized the urgency of making the supervising teacher aware of his role as co-trainer of the student interns.

Improving the Learning in Life Education for Young Children Aged 3 to 6 Years: A Review on the Research Themes of Early Childhood Life Education in Taiwan

The National Digital Library of Theses and Dissertations and the NCL (National Central Library) Taiwan Periodical Literature database were used to analyze dissertations and journal articles on early childhood life education. The researcher explored the research themes of life education for young children aged 3 to 6 years in Taiwan and offered strategies for improving learning in early childhood life education. Eight categories of themes were examined. In addition, the curriculum development of learning in early childhood life education was identified: (1) life event core curriculum, (2) sympathy core curriculum, (3) example core curriculum, and (4) anima core curriculum. Several teaching approaches of learning in early childhood life education are proposed: (1) teaching through picture books, (2) learning through experience, (3) teaching through instructional media, (4) teaching through concept mapping, (5) teaching through stories, and (6) teaching through parent–teacher collaboration. Developing and implementing the strategies of learning in early childhood life education is crucial for cultivating psychological wellbeing in young children and improving the quality of Taiwan’s early childhood education system.

Is the oral health of visually impaired children and adolescents different compared to their sighted peers?

Data sources The review searched for articles via PubMed, Web of Science, Scopus, and Ovid. OpenGrey and the Brazilian Digital Library of Thesis and Dissertations (BDTD) were used to search for grey literature. As well as a manual searches of the reference lists from the included studies, a Google Scholar search was undertaken and the first 300 hits were screened. There was no restriction on date or language.Study selection Two authors screened initially 10% of the abstracts against the inclusion and exclusion criteria and then a calibration calculation was completed showing excellent agreement (kappa coefficient = 0.93). In phase one, abstracts were screened independently between the same two authors and discrepancies were discussed and resolved. In phase two, the full articles of those abstracts accepted were screened, as well as those whose abstracts were unavailable. Discrepancies were discussed with a third author for the final decision.Data extraction and synthesis Data extracted included: study characteristics (authors, year of publication, study design, country, sampling, the presence of a pilot study, aim, calibration and losses); population (age range and sex, sociodemographics and sample size); exposure (eligibility criteria and type and classification criteria of vision impairment); and outcome (prevalence and mean and standard deviation of oral health issues, such as dental plaque, gingivitis, calculus, periodontitis, oral hygiene [OH], dental caries and traumatic dental injuries [TDI]). Discrepancies were discussed with a third author for the final decision. In total, 15 studies were included in the systematic review and 12 in the meta-analysis. For the meta-analysis, heterogeneity was measured using I2 statistics.Results The meta-analysis found visually impaired children and adolescents had significantly higher levels of plaque (mean difference [MD] = 0.80; 95% confidence interval [CI] = 0.58-1.02; I2= 96%), gingival inflammation (MD = 0.69; 95% CI = 0.02-1.37; I2 = 100%), calculus (MD = 0.04; 95% CI = 0.03-0.06; I2 = 0%), OH indices (MD = 0.71; 95% CI = 0.24-1.18; I2 = 97%) and decayed missing filled surface (DMFS/dmfs) (MD = 0.90; 95% CI = 0.68-1.13; I2 = 26%) compared to sighted peers. TDI were statistically significantly higher (OR = 3.86; 95% CI = 2.63-5.68; I2 = 0%) in visually impaired children and adolescents. There was no significant difference in decayed missing filled teeth and DMFS/dmfs or caries.Conclusions Children and adolescents who are visually impaired are at greater risk of TDI and levels of dental plaque, gingival inflammation, calculus and DMFS and poorer OH. Furthermore, robust homogenous studies are required to strengthen any evidence of association between oral health outcomes and visual impairment in children and adolescents. Future research should also explore the directionality of these relationships.

O USO/ABUSO DE SUBSTÂNCIAS PSICOATIVAS NA COMUNIDADE ACADÊMICA DO ENSINO SUPERIOR: PESQUISA BIBLIOGRÁFICA

This article investigates the use/abuse of psychoactive drugs in academic environments, since research indicates a significant increase in the recurrence of illicit drugs in public and private schools, opening space for reflection on the possible use/abuse in teaching. higher education, especially in the investigation of the effects of a neoliberal society that goes beyond the demands of results, thus inflicting new forms of malaise. To this end, a bibliographic review was carried out using the Scientific Electronic Library Online database, SciELO, Capes Periodicals, Digital Library of Theses and Dissertations, Academic Virtual Library, Academic Google, as well as the theoretical foundation by the psychoanalytic framework. Through these resources, it was possible to verify that in the last ten years the population of working age, highlighting the age group between 19-45 years of age, has been using psychoactive drugs a little more than expected, considering the regulation and prevention policies. Thus, it was possible to build reflection paths about the possible reverberations of the results found, regardless of the agreement with a prohibitionist and legalistic perspective.

Current status of glanders in Brazil: recent advances and challenges.

Glanders is an infectious disease that causes serious damage to the equine production chain in countries where it occurs endemically and poses a risk to public health. This study aimed to conduct an integrative review of the advances in the knowledge of glanders in Brazil over the last three decades since its re-emergence. Documentary research was conducted for the period between the years 2000 and 2022. SCOPUS and PUBMED databases were used to search for scientific articles, dissertations, and thesis, in addition to the Brazilian Digital Library of Thesis and Dissertations (BDTD). A total of 41 documents were retrieved, including 12 dissertations, five theses, and 24 scientific articles. The Federal Rural University of Pernambuco (UFRPE) group provided a noteworthy amount of material on this topic (25 documents, four theses, three dissertations, and 18 scientific articles). During this period, ten dissertations, one thesis, and six scientific articles published by other groups in other states of the Federation were also identified. It was concluded that there was a significant number of scientific publications with relevant data on the clinical, epidemiological, pathological, microbiological, serological, and molecular characteristics of glanders disease in Brazil. Additionally, training of human resources regarding this disease led to an increase in the nucleation of research groups, especially in the northeast region of Brazil. Despite significant advances, new research groups and specific funding are still needed for the development of more accurate diagnostic methods, immunizing production, training of veterinarians to recognize the disease, and more robust programs to control and eradicate the disease in Brazil.

S10-2 Instruments for the analysis of national-level physical activity and sedentary behaviour policies: a systematic review

BackgroundResearchers and policy makers have developed and used a variety of instruments to assess physical activity policies. Data on the available instruments and their properties have never been summarised in a systematic way. In this review we, therefore, aimed to identify and critically assess available instruments for the analysis of national-level physical activity and sedentary behaviour policies and provide recommendations for their future use.MethodsA systematic search of grey and academic literature was conducted in Scopus, SPORTDiscus, PubMed/MEDLINE, Web of Science, Networked Digital Library of Theses and Dissertations, and Open Access Theses and Dissertations, on the websites of three large international organisations for physical activity promotion, and using Google. The Comprehensive Analysis of Policy on Physical Activity (CAPPA) framework was used to assess and classify the instruments, based on their purpose, the policy sectors and scope of analysis they cover, and the policy types and stages of policy cycle they inquire about.ResultsAmong a total of 22,071 screened references, we found 26 publications describing 16 instruments that met the inclusion criteria. All the available instruments are intended for analysing some aspects of physical activity policy. Only two instruments include questions about sedentary behaviour policy. None of the instruments can be used to analyse all the relevant policy components. Only a few instruments refer to the agenda-setting and endorsement/legitimisation stages, the effects of policy, and the research and tourism sectors. The termination and succession stages of the policy cycle and unwritten formal statements and informal policies were not addressed by any of the available instruments.ConclusionOur findings indicated there is a need to design new instruments or adapt the existing ones to facilitate a more comprehensive analysis of national physical activity and sedentary behaviour policy. It would be extremely time-consuming to analyse all important components of physical activity and sedentary behaviour policy in a single analysis; hence the development of complementary instruments, where each one of them inquires about a specific policy component, might be a way forward.

Accuracy and Precision of Consumer-Grade Wearable Activity Monitors for Assessing Time Spent in Sedentary Behavior in Children and Adolescents: Systematic Review.

BackgroundA large number of wearable activity monitor models are released and used each year by consumers and researchers. As more studies are being carried out on children and adolescents in terms of sedentary behavior (SB) assessment, knowledge about accurate and precise monitoring devices becomes increasingly important.ObjectiveThe main aim of this systematic review was to investigate and communicate findings on the accuracy and precision of consumer-grade physical activity monitors in assessing the time spent in SB in children and adolescents.MethodsSearches of PubMed (MEDLINE), Scopus, SPORTDiscus (full text), ProQuest, Open Access Theses and Dissertations, DART Europe E-theses Portal, and Networked Digital Library of Theses and Dissertations electronic databases were performed. All relevant studies that compared different types of consumer-grade monitors using a comparison method in the assessment of SB, published in European languages from 2015 onward were considered for inclusion. The risk of bias was estimated using Consensus-Based Standards for the Selection of Health Status Measurement Instruments. For enabling comparisons of accuracy measures within the studied outcome domain, measurement accuracy interpretation was based on group mean or percentage error values and 90% CI. Acceptable limits were predefined as –10% to +10% error in controlled and free-living settings. For determining the number of studies with group error percentages that fall within or outside one of the sides from previously defined acceptable limits, two 1-sided tests of equivalence were carried out, and the direction of measurement error was examined.ResultsA total of 8 studies complied with the predefined inclusion criteria, and 3 studies provided acceptable data for quantitative analyses. In terms of the presented accuracy comparisons, 14 were subsequently identified, with 6 of these comparisons being acceptable in terms of quantitative analysis. The results of the Cochran Q test indicated that the included studies did not share a common effect size (Q5=82.86; P<.001). I2, which represents the percentage of total variation across studies due to heterogeneity, amounted to 94%. The summary effect size based on the random effects model was not statistically significant (effect size=14.36, SE 12.04, 90% CI −5.45 to 34.17; P=.23). According to the equivalence test results, consumer-grade physical activity monitors did not generate equivalent estimates of SB in relation to the comparison methods. Majority of the studies (3/7, 43%) that reported the mean absolute percentage errors have reported values of <30%.ConclusionsThis is the first study that has attempted to synthesize available evidence on the accuracy and precision of consumer-grade physical activity monitors in measuring SB in children and adolescents. We found very few studies on the accuracy and almost no evidence on the precision of wearable activity monitors. The presented results highlight the large heterogeneity in this area of research.Trial RegistrationPROSPERO CRD42021251922; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=251922

The Effect of Dry Care on the Time of Umbilical Cord Separation in Newborns: A Systematic Review and Meta-Analysis

There are many different approaches to umbilical cord care in clinical practice. Dry care is recommended by the WHO based on its ease of implementation and relatively low cost. However, the effect of dry care on the time of umbilical cord separation and related complications require further study. The aim of this study was to conduct a systematic review and meta-analysis of randomized controlled trials to evaluate the effect of dry care on the time of umbilical cord separation and related adverse events in newborns. A literature search was conducted of articles published before December 2021 in the Cochrane Library, PubMed, Medline, CINAHL, Embase, Airiti Library, and National Digital Library of Theses in Taiwan databases. The research quality of the identified articles was assessed using the Modified Jadad Scale. Statistical analyses were performed using Review Manager, version 5.3, with statistics reported as mean differences with 95% confidence intervals. Seven randomized controlled trials covering a total of 27,037 newborns were identified for analysis. Umbilical cord care in these studies included the following approaches: dry care, alcohol, chlorhexidine (CHX), mother's milk, and salicylic sugar powder (SSP). The results of the meta-analysis showed that umbilical cord separation time was significantly lower for the dry care approach compared to the alcohol approach (MD: -1.78 days, 95% CI: -2.4 to -1.16, three studies, n = 2,102) but not significantly different than the CHX approach (MD: -0.15 days, 95% CI [-1.99, 1.69], two studies, n = 10,519). Notably, the umbilical cord separation time for both mother's milk (MD: 1.19 days, 95% CI [0.82, 1.56], three studies, n = 730) and SSP (MD: 4.9 days, 95% CI [3.71, 6.09], one study, n = 92) approaches were reported as significantly less than the dry care approach. In addition, the CHX approach was associated with significantly fewer cord-related adverse events, while the alcohol, mother's milk, and SSP approaches were associated with rates of cord-related adverse advents similar to dry care. Because using dry care for umbilical cord care shortens the cord separation time compared to the alcohol approach and does not increase the incidence of omphalitis, this approach should be the first choice for cord care. Both mother's milk and SSP approaches are also associated with shorter umbilical cord separation times without adverse effects, and may be used as alternatives to dry care in umbilical cord care.

Effect of buttonhole cannulation versus rope-ladder cannulation in hemodialysis patients with vascular access: A systematic review and meta-analysis of randomized/clinical controlled trials.

Background:Safe and effective arteriovenous fistula (AVF) puncture techniques must be used to reduce harm to hemodialysis patients. The relative benefits of buttonhole (BH) cannulation over those of rope ladder (RL) cannulation for AVF remain unclear and inconsistent.Methods:This systematic review and meta-analysis was conducted in accordance with Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines. Literature searches were conducted in June 2020 in multiple scientific databases including Cochrane library, CINAHL, PubMed/ Medline, Airiti Library, National Digital Library of Theses and Dissertations in Taiwan, Google scholar, Embase, and ProQuest. We included all randomized controlled trials (RCTs) and clinical controlled trials (CCTs) that explored the efficacy of BH cannulation in hemodialysis patients. These included reports published in either English or Chinese that enrolled adults aged 18 years or older who underwent hemodialysis using an autogenous AVF. Studies that showed poor design, such as use of a self-control group or no control group, were excluded from analysis. The critical appraisal skills program checklist for RCTs were used to assess the quality of the evidence and RevMan software were used to perform the meta-analysis.Results:Fifteen studies (11 RCTs and 4 CCTs) met the inclusion criteria and were used for the meta-analysis. Meta-analysis showed that BH cannulation significantly reduced aneurysm formation (RR = 0.18, 95% confidence interval [CI] [0.1, 0.32]), stenosis (RR = 0.44, 95% CI [0.25, 0.77]), thrombosis formation (RR = 0.4, 95% CI [0.2, 0.8]), and hematoma (RR = 0.63, 95% CI [0.40, 0.99]) and showed no differences in AVR infection (≦6 months, RR = 2.17, 95% CI [0.76, 6.23]; >6 months, RR = 2.7, 95% CI [0.92, 7.92]) compared to RL cannulation.Conclusions:Given the benefits of BH, this meta-analysis found that BH cannulation should be recommended as a routine procedure for hemodialysis but that hospitals and hemodialysis clinics should strengthen staff knowledge and skills of BH cannulation to reduce the risk of AVF infection.

Dietary and nutritional interventions in children with cerebral palsy: A systematic literature review.

Cerebral palsy is an extremely severe brain injury associated with multiple nutritional and clinical issues, such as underweight, gastroesophageal reflux, constipation, and nutrient deficiency. Evidence-based dietary and nutritional interventions may improve the quality of life of children with cerebral palsy. Systematically review randomized clinical trials evaluating nutritional and dietary interventions in the clinical, nutritional, and neurodevelopmental aspects of children with cerebral palsy. A search was performed in electronic databases (LILACS, Medline, Web of Science, Embase, Scopus, Cochrane Library, ClinicalTrials.gov, Brazilian Digital Library of Theses and Dissertations, ProQuest Dissertations and Theses Database, OpenGrey) using keywords. The search was firstly performed in May 2020 and updated on June 18th, 2021. Eligible studies were randomized clinical trials, that included children between 2 and 12 years old, and evaluated the effect of nutritional or dietetic interventions on clinical, nutritional or neurodevelopmental outcomes. Risk of bias was investigated using the RoB-2 tool. The study was registered on PROSPERO (CRD42020181284). Fifteen studies were selected. Positive results included the use of whey-based or pectin-enriched enteral formulas for gastroesophageal reflux (n = 6); 25-hydroxy-vitamin D supplementation for hypovitaminosis D (n = 2); supplementation with lipid mixture or diet with high-density energy for improvements in anthropometric measures (n = 2); supplementation with probiotics, prebiotics, symbiotics or magnesium for constipation (n = 2); nutritional support system for gross motor function (n = 1); lactoferrin and iron hydroxide polymaltose for iron deficiency anemia (n = 1); and educational intervention to improve feeding skills (n = 1). The overall risk of bias was high for 60% of the studies, and some concerns were raised for the remaining 40%. Some promising dietary and nutritional interventions may promote important clinical improvements for patients with cerebral palsy. However, evidence is weak, as few clinical trials have been published with many methodological errors, leading to a high risk of bias.

Association between delayed initiation of treatment indications and survival in patients with cervical cancer: A systematic review and meta-analysis protocol.

BackgroundCervical cancer is a growing public health problem globally. Despite the availability of management options, the progression of the disease as a function of waiting time may challenge the effort to attain a desired outcome. There is a conflicting report on the role of waiting time to initiate an appropriate treatment in improving patients’ survival.ObjectiveThis review aims to evaluate the association between delayed time to initiate any treatment indication with survival in patients with cervical cancer.MethodsAn internet-based literature search will be performed using text words, MESH terms and truncated words in databases, namely MEDLINE, Cochrane CENTRAL, EMBASE, Web of Science and Scopus. Grey literature searches in Google Scholar, Networked Digital Library of Theses and Dissertations (NDLTD) and Dissertations and Theses Global will be made. All articles published until 30th of December 2021 on human subjects will be searched without a language restriction. Studies which fulfil the inclusion criteria will be screened in full reading, selected, appraised and assessed for methodological quality by two independent reviewers. Data on participants, study methods, interventions, and outcomes will be abstracted. Included studies will be pooled for meta-analysis. Microsoft-Excel and R packages will be employed to carry out the statistical analysis. Heterogeneity will be assessed using Cochrane Q statistic, Tau2, and I2. Results will be reported as a function of 4-week delay in treatment initiation and the corresponding hazard ratio (HR) at 95% confidence interval. Statistical significance will be considered at P<0.05.Trial registrationPROSPERO registration number: CRD42022299689.

EFFECTIVENESS OF THYMOKINO IN ALZHEIMER’S DISEASE: A SYSTEMATIC REVIEW IN RAT MODELS

This study is a systematic review and was prepared according to the PRISMA checklist and Cochrane guide. Science Direct, Web of Science, SCOPUS, Springer Link, Networked Digital Library of Theses &amp; Dissertations, Ovid, CINAHL, Pubmed, Cochrane Library, using the Proquest database “Alzheimer Disease”, “Alzheimer”, “A.D”., “Thymoquinone” , “TQ”, “Nigella Sativa”, “NS” etc. Search was made using keywords. The abstracts of 251 theses, which were scanned between March and April 2022 and constitute the universe, were systematically examined and 18 articles suitable for the purpose of the research formed the sample of the research.

A Review of Scientific Papers on the (Tele) Work of Postgraduate Professors

Before the implementation of compulsory remote work due to the Covid-19 pandemic, postgraduate professors already exercised telework in their homes, informally. Thus, the objective is to analyze the scientific production of telework or work of postgraduate professors. A systematic review of articles in the SCOPUS, Web of Science, and Scielo databases and of theses and dissertations in the Brazilian Digital Library of Theses and Dissertations was carried out. We sought to classify the research found by themes and identify the content of the results that researchers found. There was a significant amount of work on the evaluation of postgraduate studies or professors, in search of improvements. Problems were noted in the professor's work in relation to the lack of training for teaching, university environment with few resources, complex activities and in a quantity that extrapolates the time of service, evaluation by results that causes negative consequences in the performance of activities as in the personal life of the professor. Telework was found in different contexts, such as ubiquitous work and the digital age, distance education, pleasure and suffering at work, and as a dimension that addresses teaching work. Since professors have already experimented with teleworking and compulsory remote work, they are subject to the positivities and negativities that it can cause, which may or may not facilitate the improvement of the problems pointed out. The research contributes to the human resources management area, by seeking to understand how professors-researchers have used this modality outside universities and potential research gaps, such as identification of control of professors’ telework since it is subjective and complex; more precise identification of the profile of professors who telework and what type; how teleworking affects the issues raised by research on professors' work; and, how was the experience of compulsory remote work during the pandemic.

Transformative Consumer Research: How has the fat body been approached from this perspective in Brazilian research?

Objective: Completing 15 years of Transformative Consumer Research in 2020, this article aims to present an overview of the Brazilian scientific production about how the fat body was approached from this research perspective in this period between 2005 and 2019.Method: To analyze the national scientific production of the fat body in TCR studies from 2005 to 2019, an integrative literature review was carried out according the review steps indicated by Cooper (1984). Thus, a search for the terms "Transformative Research", "Transformative Consumer Research" and "TCR" was carried out in the annals of the main administration events; national journals registered in the SPELL database with Qualis/CAPES 2013-2016 ratings in the strata from B5 to A2 in the area of Administration; and the Brazilian Digital Library of Theses and Dissertations (BDTD).Findings: The results point to a significant growth of publications in TCR in the years 2018 and 2019 but indicate the need to study other groups of vulnerable consumers, in addition to those with some disability, such as consumers of the fat body archetype.Originality: The present study has merit since the results are important to broaden the discussion about the fat body within the theme of consumption, allowing to give visibility to this debate and bringing the theme to the knowledge of managers and market professionals who can contribute to expanding access to consumption by this public; in addition to, specifically, contributing to the propagation of studies from the perspective of transformative research and social marketing, encouraging new researchers and new studies within the aforementioned scopes.

Therapeutic potential of silver nanoparticle-based dressing in the healing process

Introduction: The skin covers the entire surface of the human body, and is considered its largest organ. The resistance of bacteria to antibiotics represents a growing concern in wound infections, this is evidenced by the fact that wounds associated with a heavy bacterial load often present healing failures, increasing healthcare costs for the patient and healing time. Objective: To evidence through national and international literature the therapeutic potential of silver nanoparticle-based dressings in the healing process. Methodology: This is a literature review of a dissertative and explanatory nature. To theoretically support this review, the Brazilian Digital Library of Theses and Dissertations (BDTD) and the Nursing Databases (BDENF) were used. The search period was from February to April 2022, with temporal delimitation from 2017 to 2022, because these were the years that most studies on the topic of interest were obtained. The Boolean searchers (AND and OR) were used: ¬ "Nanoparticle-based dressing OR "Pressure injury" AND "Nanoprene therapy" AND "Multiprofessional team" in BDENF and BDTD, interrelated with the Boolean operators AND and OR. This study included original articles, available in full, case studies, clinical studies, randomized studies, theses and dissertations on the topic in question, published from 2016 to 2022, in English and Portuguese. As exclusion criteria, it was decided not to use articles that were not adjusted to the object of study, which ran away from the theme proposed by the authors, those that were duplicated in electronic databases, incomplete texts, unavailable in full, literature reviews, guides, technical manuals and letters to the reader. A total of 211 articles were found in the BDTD and 17 in the BDENF database, totaling 228 studies found. Of these, after applying the inclusion and exclusion criteria, 211 were excluded and 17 studies were selected because they met the study objective. Results: The AgNP-based dressing, presents great potential in pharmaceutical, therapeutic and biomedical applications, and can be applied in the composition of topical products such as ointments, gels and adhesives.Conclusion: Dressings based on silver nanoparticles (AgNP) are being widely used in biomedical sciences, being relevant to circumvent bacterial resistance to antibiotics, improving the quality of life of affected patients and consequently reducing hospital costs.