The article presents the latest methodology of systematic lexicographic description of the Ukrainian worldview of the second half of the XX – beginning of the XXI centuries, on the basis of which lexicographers of the Institute of Ukrainian Language of the NAS of Ukraine compile a new explanatory dictionary of creative personalities. The dictionary contains a consolidated lexicon and artistic means of language of the leading Ukrainian writers, publicists and translators (Oles Honchar, Yevhen Sverstyuk, Hryhor Tyutyunnyk, Ivan Dziuba, Mykola Lukash, Yuriy Andrukhovych, Oksana Zabuzhko), which provides perspective modeling of the language and conceptual picture of the world, research of idiosyncrasies of creative personalities, elucidation of laws of language and society development. The dictionary is innovative in terms of register and lexicographic methods of systematic vocabulary description. It presents the vocabulary of the era of totalitarianism and the post-totalitarian period, which is not evidenced by explanatory dictionaries. For the lexicographic reproduction of the conceptual dominants of these periods, a system of hyperlinks between dictionary entries compiled from the works of different authors was used. The dictionary combines information about the individual author's worldview and the common understanding of the key concepts of the era by writers. Innovative introduction of culturological and encyclopedic information provides a lexicographic description of the achievements of Ukrainian language creation against the background of universal cultural values. In the future, it is possible to make a systematic lexicographic description of lexical and artistic heritage of the latest Ukrainian writers, the formation of a dictionary of the active type, a common ideographic dictionary. The combined work of the Ukrainian academic lexicographers provides macroscientific research on the development of language and society, deepening the theory of lexicology, lexicography, derivatology, linguoculturology, linguosociology, stylistics, development of the theory of integrated linguistic research.