Left Eyelid Ptosis Research Articles

Oculomotor palsy with cyclic spasms: a case report

Oculomotor palsy with cyclic spasms is a rare, non-progressive disorder in which the muscles innervated by the third cranial nerve undergo alternating rhythmic spasm and paralysis. An 18-year-old male was referred with left upper eyelid ptosis present since birth. On examination we noted cyclic movements of the left eyelid and pupil. The cycle consisted of periods of ptosis and mydriasis alternating with eyelid retraction with miosis. The interpalpebral fissure measured 2 mm in the paralytic phase and 11 mm in the spastic phase. The pupil diameter varied from 3 mm to 6 mm. Six cycles were observed in 5 minutes. The patient had no voluntary control over his left eyelid, nor over the other muscles innervated by the third nerve. The affected eye was deeply amblyopic and exotropic. Systemic evaluation and cranial MRI gave normal results. A therapeutic trial with oral baclofen (30 mg/day), a central muscle relaxant drug, was ineffective in suppressing the cyclic movements.

眼窩尖端部症候群を呈した蝶形骨洞嚢胞例

A 63-year-old man was admitted with left eyelid ptosis, diplopia, bilateral reduced visual acuity and ophthalmoplegia. These clinical symptoms were compatible with a diagnosis of orbital apex syndrome.CT was very helpful in the diagnosis. The cause was thought to be due to a mucocele in the sphenoidal sinus. Intra-nasal operation was performed under local anesthesia. These symptoms mentioned above disappeared rapidly after surgery.

173 A CASE OF PRIMARY OVARIAN FAILURE ASSOCIATED WITH INCONTINENTIA PIGMENTI AND MULTIPLE MINOR ANOMALIES

The causes of primary ovarian failure except for Turner's syndrome are extremely rare. We have experienced a 16 5/12-year-old girl who presented with short stature (137.5 cm, -3 S.D. ) and lack of secondary sexual development. Physical examination revealed immature face, typical skin changes of fading stage of incontinentia pigmenti, hemihypertrophy of extremities, ptosis of left eye lid, low set and asymmetrical ears, low posterior hair lines and atrophic nails. Bone age was 10 6/12 years. Lab data showed low estradiol (E2, 10.0pg/ml ) with high FSH (139 mIU/ml) and LH (105.8 mIU/ml). FSH and LH responded excessively to LH-RH and primary ovarian failure was suspected. Chromosome analysis revealed normal 46,X X karyotype by peripheral lymphocytes and skin fibroblasts. Laparoscopic examination revealed bilateral streak ovaries and a hypoplastic uterus. IVP demonstrated no urinary abnormalities. Bilateral perceptive deafness were found and her IQ was 104. She was placed on estrogen therapy.

Pathogenesis of ophthalmoplegic migraine.

THE PROBLEM of the origin of the ocular paralyses occurring in the course of migraine, referred to as ophthalmoplegic migraine, remains unsolved. Of the several concepts which have been proposed to explain them, that of cerebral aneurysm has received wide acceptance, though there has been little evidence to support it. In order to test the validity of the concept of cerebral aneurysm as a cause of ophthalmoplegic migraine, two patients with this condition were studied by means of arteriography. In neither instance was an aneurysm demonstrated. <h3>REPORT OF CASES</h3><h3>Case 1.</h3> —M. R. (J. H. no. R-54069). Recurrent pain in left side of head and left eye associated with ptosis of left eyelid, diplopia and partial oculomotor paralysis. Normal left internal carotid arteriogram on two occasions (1948 and 1950). No evidence of aneurysm to account for ophthalmoplegic migraine. The patient, a white woman aged 56, first appeared for relief on Oct. 26,

Bacteriological Observations on a Case of Meningo-Encephalitis.

On December 12, 1933, a nurse became suddenly ill and repeatedly vomited bile stained material. The following morning she had a severe chill, a temperature of 101 °F., severe headache, some rigidity of the neck and a doubtful Kernig's sign. A day later her temperature reached 105.3°F. and the meningeal symptoms were more marked. During the first 10 days of her illness the more prominent symptoms were: fever, headache, occipital tenderness, rigidity of the neck, strabismus, ptosis of left eyelid, diplopia, twitching muscle fasciculi and lethargy from which she could be fairly easily roused. There was gradual improvement after about the tenth day. Ten weeks after the onset there remained some speech defect, difficulty in feeding herself, dysmetria, sprawling gait, slight nodding of head, emotional instability and impaired memory.Spinal fluid obtained December 15 was hazy and contained 812 cells per cu. mm. (95% small lymphocytes). The sugar content was 37 mg. per 100 cc. and the gold curve 0023321111. Subse...